Science Explorer Back to mapMap

Most cited papers in Kruppel-like factors research

What are the most cited papers in Kruppel-like factors research?

The most cited paper in Kruppel-like factors research is "Angiogenesis in cancer, vascular, rheumatoid and other disease" (Judah Folkman, 1995), with 7,691 citations. Next come "Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus" (5,907) and "Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases" (5,663).

Showing 50 of 100 papers. Every paper with more than 873 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Angiogenesis in cancer, vascular, rheumatoid and other disease Judah Folkman · Nature Medicine 1995 7,691
2 Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus Yigong Shi, Joan Massagué · Cell Open access Jun 2003 5,907
3 Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases Bryan T. MacDonald, Keiko Tamai, Xi He · Developmental Cell Open access Jul 2009 5,663
4 Wnt/β-Catenin Signaling and Disease Hans C. Clevers, Roel Nusse · Cell Open access Jun 2012 5,649
5 Wnt/β-Catenin Signaling in Development and Disease Hans C. Clevers · Cell Open access Nov 2006 5,617
6 Angiogenesis in health and disease Peter Carmeliet · Nature Medicine 30 May 2003 4,294
7 TGFβ in Cancer Joan Massagué · Cell Open access Jul 2008 3,950
8 TGF-β signalling from cell membrane to nucleus through SMAD proteins Carl‐Henrik Heldin, Kohei Miyazono, Peter ten Dijke · Nature Dec 1997 3,705
9 TGFβ signalling in context Joan Massagué · Nature Reviews Molecular Cell Biology ReviewOpen access 20 Sep 2012 3,213
10 VEGF receptor signalling ? in control of vascular function Anna‐Karin Olsson, Anna Dimberg, Johan Kreuger et al. · Nature Reviews Molecular Cell Biology Review 21 Apr 2006 3,138
11 p21 in cancer: intricate networks and multiple activities Tarek Abbas, Anindya Dutta · Nature reviews. Cancer ReviewOpen access 14 May 2009 2,790
12 Fibroblast growth factor signalling: from development to cancer Nicholas C. Turner, Richard Philip Grose · Nature reviews. Cancer Review 22 Jan 2010 2,724
13 Notch signalling: a simple pathway becomes complex Sarah J. Bray · Nature Reviews Molecular Cell Biology Review 21 Aug 2006 2,644
14 Convergence of Wnt, ß-Catenin, and Cadherin Pathways William James Nelson, Roel Nusse · Science Open access 4 Mar 2004 2,531
15 Role of platelet-derived growth factors in physiology and medicine Johanna Andræ, Radiosa Gallini, Christer Betsholtz · Genes & Development Open access 15 May 2008 2,479
16 Smad transcription factors Joan Massagué, Joan Seoane, David Wotton · Genes & Development Open access Dec 2005 2,466
17 The Fibroblast Growth Factor signaling pathway David M. Ornitz, Nobuyuki Itoh · Wiley Interdisciplinary Reviews Developmental Biology ReviewOpen access 13 Mar 2015 2,129
18 FGF-21 as a novel metabolic regulator Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Köester et al. · Journal of Clinical Investigation Open access 3 May 2005 2,126
19 Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism Chunming Liu, Yiming Li, Mikhail A. Semenov et al. · Cell Open access Mar 2002 2,095
20 Genomewide Association Analysis of Coronary Artery Disease Nilesh J. Samani et al. · New England Journal of Medicine Open access 18 Jul 2007 2,062
21 Neurofilaments as biomarkers in neurological disorders Michael Khalil, Charlotte Elisabeth Teunissen, Markus Otto et al. · Nature Reviews Neurology ReviewOpen access 31 Aug 2018 2,042
22 The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells Marc van de Wetering, Elena Lanchares Sancho, Cornelis L. Verweij et al. · Cell Open access Oct 2002 2,026
23 How cells read TGF-β signals Joan Massagué · Nature Reviews Molecular Cell Biology Review Dec 2000 1,910
24 SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS Xin‐Hua Feng, Rik Derynck · Annual Review of Cell and Developmental Biology Review Jul 2005 1,881
25 Vascular Endothelial Growth Factor and Angiogenesis Ann Hoeben, Bart Landuyt, Martin Highley et al. · Pharmacological Reviews Dec 2004 1,852
26 Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation Thomas N. Sato, Yuzuru Tozawa, Urban Deutsch et al. · Nature Jul 1995 1,833
27 Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis Mats Hellström, Li‐Kun Phng, Jennifer J. Hofmann et al. · Nature 28 Jan 2007 1,801
28 Controlling TGF-beta signaling. Joan Massagué, Ye-Guang Chen · PubMed 15 Mar 2000 1,796
29 Non-Smad pathways in TGF-β signaling Ying E. Zhang · Cell Research Open access 30 Dec 2008 1,741
30 Signaling Mechanisms Regulating Endothelial Permeability Dolly Mehta, Asrar B. Malik · Physiological Reviews Review 21 Dec 2005 1,732
31 Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway Eek‐hoon Jho, Tong Zhang, Claire Domon–Dell et al. · Molecular and Cellular Biology Open access Feb 2002 1,710
32 Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases Peter Carmeliet, Rakesh K. Jain · Nature Reviews Drug Discovery Review Jun 2011 1,705
33 Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions Peter Carmeliet et al. · Nature Medicine Open access May 2001 1,688
34 Large-scale association analysis identifies new risk loci for coronary artery disease Panos Deloukas et al. · Nature Genetics Open access183 authors 2 Dec 2012 1,681
35 Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature May 1998 1,645
36 Secreted antagonists of the Wnt signalling pathway Yoshiaki Kawano, Robert M. Kypta · Journal of Cell Science 29 May 2003 1,590
37 Controlling TGF-β signaling Joan Massagué, Ye‐Guang Chen · Genes & Development Open access 15 Mar 2000 1,576
38 Wnt signal transduction pathways Yuko Komiya, Raymond Habas · Organogenesis Open access Apr 2008 1,544
39 The glamour and gloom of glycogen synthase kinase-3 Richard Scott Jope, Gail V.W. Johnson · Trends in Biochemical Sciences Review 15 Jan 2004 1,527
40 Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States Michael K. Badman, Pavlos Pissios, Adam Richard Kennedy et al. · Cell Metabolism Open access Jun 2007 1,501
41 A causal role for E-cadherin in the transition from adenoma to carcinoma Anne‐Karina T. Perl, Petra Wilgenbus, Ulf Dahl et al. · Nature Mar 1998 1,421
42 Regulation of bone mass by Wnt signaling Venkatesh Krishnan · Journal of Clinical Investigation Open access May 2006 1,402
43 Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors Michael David Gordon, Roel Nusse · Journal of Biological Chemistry Open access 23 Jun 2006 1,340
44 Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs Eduard Hergenreider, Susanne Heydt, Karine Tréguer et al. · Nature Cell Biology 10 Feb 2012 1,313
45 Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis Peter Carmeliet et al. · Cell Open access Jul 1999 1,295
46 Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets Sandrine Boyault, David S. Rickman, Aurélien de Reyniès et al. · Hepatology Open access 22 Dec 2006 1,288
47 Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2 Marion Trommsdorff, Michael Gotthardt, Thomas Hiesberger et al. · Cell Open access Jun 1999 1,271
48 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease Pim van der Harst, Niek Verweij · Circulation Research Open access 6 Dec 2017 1,269
49 KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis Laura S. Shankman, Delphine Gomez, Olga A. Cherepanova et al. · Nature Medicine Open access 18 May 2015 1,253
50 HES and HERP families: Multiple effectors of the notch signaling pathway Tatsuya Iso, Larry Kedes, Yasuo Hamamori · Journal of Cellular Physiology 23 Jan 2003 1,250

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.