Most cited papers in Lipid Membrane Structure and Behavior
What are the most cited papers in Lipid Membrane Structure and Behavior?
The most cited paper in Lipid Membrane Structure and Behavior is "A simple method for displaying the hydropathic character of a protein" (Jack Kyte, Russell F. Doolittle, 1982), with 23,233 citations. Next come "Functional rafts in cell membranes" (9,793) and "The Fluid Mosaic Model of the Structure of Cell Membranes" (9,137).
Showing 50 of 100 papers. Every paper with more than 1,836 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A simple method for displaying the hydropathic character of a protein Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology | May 1982 | 23,233 |
| 2 | Functional rafts in cell membranes Kai Simons, Elina Ikonen · Nature | Jun 1997 | 9,793 |
| 3 | The Fluid Mosaic Model of the Structure of Cell Membranes Sherwin J. Singer, Garth L. Nicolson · Science | 18 Feb 1972 | 9,137 |
| 4 | CHARMM general force field: A force field for drug‐like molecules compatible with the CHARMM all‐atom additive biological force fields Kenno Vanommeslaeghe, Elizabeth Hatcher, Chitrangada Acharya et al. · Journal of Computational Chemistry | 2 Jul 2009 | 7,826 |
| 5 | Membrane lipids: where they are and how they behave Gerrit van Meer, Dennis R. Voelker, Gerald W. Feigenson · Nature Reviews Molecular Cell Biology | 23 Jan 2008 | 7,319 |
| 6 | Elastic Properties of Lipid Bilayers: Theory and Possible Experiments W. Helfrich · Zeitschrift für Naturforschung C | Dec 1973 | 6,290 |
| 7 | Lipid rafts and signal transduction Kai Simons, Derek K. Toomre · Nature Reviews Molecular Cell Biology | Oct 2000 | 6,284 |
| 8 | The MARTINI Force Field: Coarse Grained Model for Biomolecular Simulations Siewert J. Marrink, Herre Jelger Risselada, Serge Yefimov et al. · The Journal of Physical Chemistry B | 15 Jun 2007 | 5,844 |
| 9 | An integrated procedure for the extraction of bacterial isoprenoid quinones and polar lipids David E. Minnikin, Anthony G. O’Donnell, Michael Goodfellow et al. · Journal of Microbiological Methods | Jul 1984 | 5,534 |
| 10 | Recent advances with liposomes as pharmaceutical carriers Vladimir P. Torchilin · Nature Reviews Drug Discovery | Feb 2005 | 5,273 |
| 11 | Short-Term Synaptic Plasticity Robert S. Zucker, Wade G. Regehr · Annual Review of Physiology | Mar 2002 | 5,135 |
| 12 | Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems M. Danaei, M. Dehghankhold, Shahla Ataei et al. · Pharmaceutics | 18 May 2018 | 4,847 |
| 13 | Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types Jeffery B. Klauda, Richard M. Venable, J. Alfredo Freites et al. · The Journal of Physical Chemistry B | 24 May 2010 | 4,838 |
| 14 | Liposomal drug delivery systems: From concept to clinical applications Theresa M. Allen, Pieter R. Cullis · Advanced Drug Delivery Reviews | Oct 2012 | 4,816 |
| 15 | Diffusion of univalent ions across the lamellae of swollen phospholipids A. D. Bangham, M. M. Standish, J.C. Watkins · Journal of Molecular Biology | Aug 1965 | 4,635 |
| 16 | CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field Jumin Lee, Xi Cheng, Jason Swails et al. · Journal of Chemical Theory and Computation | 12 Nov 2015 | 4,508 |
| 17 | Lipid Rafts As a Membrane-Organizing Principle Daniel Lingwood, Kai Simons · Science | 31 Dec 2009 | 4,485 |
| 18 | Models for the Specific Adhesion of Cells to Cells George I. Bell · Science | 12 May 1978 | 4,445 |
| 19 | Cell Migration: A Physically Integrated Molecular Process Douglas A. Lauffenburger, Alan F. Horwitz · Cell | Feb 1996 | 4,009 |
| 20 | Evidence for the Formation of Symmetric and Asymmetric DLPC-DAPC Lipid Bilayer Domains Markus Ritter, Sabine Schmidt, Martin Jakab et al. · Cellular Physiology and Biochemistry | 2013 | 3,933 |
| 21 | PERIODATE-LYSINE-PARAFORMALDEHYDE FIXATIVE A NEW FIXATIVE FOR IMMUNOELECTRON MICROSCOPY Ian W. McLean, Paul K. Nakane · Journal of Histochemistry & Cytochemistry | Dec 1974 | 3,826 |
| 22 | Identification of two related pentapeptides from the brain with potent opiate agonist activity Joel W. Hughes, Terry Smith, Hans Walter Kosterlitz et al. · Nature | Dec 1975 | 3,808 |
| 23 | Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art R Müller · European Journal of Pharmaceutics and Biopharmaceutics | 3 Jul 2000 | 3,758 |
| 24 | Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes Katarina Trajković, Chieh Hsu, Salvatore Chiantia et al. · Science | 28 Feb 2008 | 3,678 |
| 25 | Polymer Vesicles Dennis E. Discher, Adi Eisenberg · Science | 9 Aug 2002 | 3,538 |
| 26 | Long-Circulating and Target-Specific Nanoparticles: Theory to Practice Seyed Moein Moghimi, Alan Christy Hunter, J. Clifford Murray · Pharmacological Reviews | Jun 2001 | 3,514 |
| 27 | Rab proteins as membrane organizers Marino Zerial, Heidi May McBride · Nature Reviews Molecular Cell Biology | Feb 2001 | 3,410 |
| 28 | Principles of bioactive lipid signalling: lessons from sphingolipids Yusuf Awni Hannun, Lina Marie Obeid · Nature Reviews Molecular Cell Biology | 23 Jan 2008 | 3,378 |
| 29 | A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants Rudy L. Juliano, Victor Wei Teik Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes | Nov 1976 | 3,310 |
| 30 | Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots George Rouser, Sidney Fleischer, Akira Yamamoto · Lipids | May 1970 | 3,301 |
| 31 | SNAP receptors implicated in vesicle targeting and fusion Thomas H. Söllner, Sidney W. Whiteheart, Michael A. Brunner et al. · Nature | 25 Mar 1993 | 3,278 |
| 32 | Complexation Thermodynamics of Cyclodextrins M.V. Rekharsky, Yoshihisa Inoue · Chemical Reviews | 14 Jul 1998 | 3,197 |
| 33 | Solid lipid nanoparticles Production, characterization and applications W. Mehnert · Advanced Drug Delivery Reviews | 25 Apr 2001 | 3,147 |
| 34 | Mechanisms of Endocytosis Gary Joseph Doherty, Harvey T. McMahon · Annual Review of Biochemistry | 24 Mar 2009 | 3,094 |
| 35 | Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy Richard A. Henderson, Joyce M Baldwin, Thomas A. Ceska et al. · Journal of Molecular Biology | Jun 1990 | 2,994 |
| 36 | FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES Deborah A. Brown, Erwin London · Annual Review of Cell and Developmental Biology | Nov 1998 | 2,963 |
| 37 | Solubilization of membranes by detergents Ari Helenius, Kai Simons · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes | Mar 1975 | 2,948 |
| 38 | Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface Deborah A. Brown, John K. Rose · Cell | Feb 1992 | 2,930 |
| 39 | Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). Rose M. Johnstone, Mohammed Adam, James R. Hammond et al. · Journal of Biological Chemistry | Jul 1987 | 2,926 |
| 40 | The effect of particle design on cellular internalization pathways Stephanie E. A. Gratton, Patricia A. Ropp, Patrick D. Pohlhaus et al. · Proceedings of the National Academy of Sciences | 12 Aug 2008 | 2,911 |
| 41 | Classical Electrostatics in Biology and Chemistry Barry H. Honig, Anthony O. Nicholls · Science | 26 May 1995 | 2,905 |
| 42 | CHARMM-GUI Membrane Builder toward realistic biological membrane simulations Emilia L. Wu, Xi Cheng, Sunhwan Jo et al. · Journal of Computational Chemistry | 7 Aug 2014 | 2,893 |
| 43 | Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis Joanna Rejman, Volker Oberle, Inge S. Zuhorn et al. · Biochemical Journal | 2004 | 2,876 |
| 44 | Phosphoinositides in cell regulation and membrane dynamics Gilbert Di Paolo, Pietro V. De Camilli · Nature | Oct 2006 | 2,811 |
| 45 | Structure of lipid bilayers John F. Nagle, Stephanie Tristram‐Nagle · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes | Nov 2000 | 2,694 |
| 46 | Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics Vitali Matyash, Gerhard Liebisch, Teymuras V. Kurzchalia et al. · Journal of Lipid Research | 16 Feb 2008 | 2,690 |
| 47 | SNAREs — engines for membrane fusion Reinhard Jahn, Richard H. Scheller · Nature Reviews Molecular Cell Biology | 16 Aug 2006 | 2,675 |
| 48 | Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins Gero Miesenböck, Dino A. De Angelis, James Edward Rothman · Nature | Jul 1998 | 2,661 |
| 49 | Secretory products of macrophages. Carl Nathan · Journal of Clinical Investigation | Feb 1987 | 2,651 |
| 50 | Effect of Surface Properties on Nanoparticle–Cell Interactions Ayush Verma, Francesco Stellacci · Small | 20 Oct 2009 | 2,638 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.