Most cited papers in Medicinal Plant Pharmacodynamics Research
What are the most cited papers in Medicinal Plant Pharmacodynamics Research?
The most cited paper in Medicinal Plant Pharmacodynamics Research is "Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs" (C. A. Winter, Edwin A. Risley, George W. Nuss, 1962), with 5,701 citations. Next come "Differential oestrogen receptor binding is associated with clinical outcome in breast cancer" (2,434) and "The JAK/STAT signaling pathway" (1,908).
Showing 50 of 100 papers. Every paper with more than 277 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs C. A. Winter, Edwin A. Risley, George W. Nuss · Experimental Biology and Medicine | Dec 1962 | 5,701 |
| 2 | Differential oestrogen receptor binding is associated with clinical outcome in breast cancer Caryn S. Ross-Innes, Rory Stark, Andrew Erich Teschendorff et al. · Nature | 2012 | 2,434 |
| 3 | The JAK/STAT signaling pathway Jason S Rawlings, Kristin M. Morey-Rosler, Douglas A. Harrison · Journal of Cell Science | 12 Mar 2004 | 1,908 |
| 4 | Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma Gentao Liu, Xiangpeng Yuan, Zhaohui Zeng et al. · Molecular Cancer | Dec 2006 | 1,802 |
| 5 | Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway Marco Antonio Meraz‐Ríos, J. Michael White, Kathleen C. F. Sheehan et al. · Cell | Feb 1996 | 1,672 |
| 6 | Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity | 1999 | 1,655 |
| 7 | Aromatase Cytochrome P450, The Enzyme Responsible for Estrogen Biosynthesis* EVAN R. SIMPSON, Mala Mahendroo, Gary Means et al. · Endocrine Reviews | Jun 1994 | 1,470 |
| 8 | Biology and biochemistry of proteinases in tumor invasion Paolo Mignatti, D. B. Rifkin · Physiological Reviews | 1993 | 1,256 |
| 9 | Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors Evan Parganas, Demin Wang, Dimitrios J. Stravopodis et al. · Cell | May 1998 | 1,164 |
| 10 | Cytokine Signaling in 2002 John J. O’Shea, Massimo Gadina, Robert D. Schreiber · Cell | Apr 2002 | 1,130 |
| 11 | Specific Inhibition of Stat3 Signal Transduction by PIAS3 Chan D. Chung, Jiayu Liao, Bin Liu et al. · Science | 5 Dec 1997 | 983 |
| 12 | Jaks and Stats in signaling by the cytokine receptor superfamily James N. Ihle, Ian Macpherson Kerr · Trends in Genetics | Feb 1995 | 907 |
| 13 | Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses Scott J. Rodig, Marco Antonio Meraz‐Ríos, J. Michael White et al. · Cell | May 1998 | 861 |
| 14 | SOCS Proteins: Negative Regulators of Cytokine Signaling Danielle L. Krebs, Douglas J. Hilton · Stem Cells | Sep 2001 | 831 |
| 15 | What does Stat3 do? David E. Levy, Chien‐Kuo Lee · Journal of Clinical Investigation | May 2002 | 816 |
| 16 | The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat Nicole Gerwin, Alison M. Bendele, S. Glasson et al. · Osteoarthritis and Cartilage | 22 Sep 2010 | 745 |
| 17 | Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation Zhe Yang, Lin Zhou, Liming Wu et al. · Annals of Surgical Oncology | 14 Feb 2011 | 722 |
| 18 | Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases Tadatsugu Taniguchi · Science | 14 Apr 1995 | 711 |
| 19 | Osteoclast differentiation by RANKL and OPG signaling pathways Nobuyuki Udagawa, Masanori Koide, Midori Nakamura et al. · Journal of Bone and Mineral Metabolism | 20 Oct 2020 | 707 |
| 20 | Signaling by the cytokine receptor superfamily: JAKs and STATs James N. Ihle, Bruce A. Witthuhn, Frederick W. Quelle et al. · Trends in Biochemical Sciences | May 1994 | 665 |
| 21 | Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis Toshiyuki Fukada, Masahiko Hibi, Yojiro Yamanaka et al. · Immunity | Nov 1996 | 665 |
| 22 | Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer Bharat Bhushan Aggarwal, Ajaikumar Bahulayan Kunnumakkara, Kuzhuvelil B. Harikumar et al. · Annals of the New York Academy of Sciences | Aug 2009 | 650 |
| 23 | Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony Lingling Zhang, Wei Wei · Pharmacology & Therapeutics | 10 Dec 2019 | 645 |
| 24 | Constitutive activation of STAT 3 in breast cancer cells: A review Kasturi Banerjee, Haluk Resat · International Journal of Cancer | 11 Nov 2015 | 635 |
| 25 | Extraction of Flavonoids From Natural Sources Using Modern Techniques Jaísa Oliveira Chaves, Mariana Corrêa de Souza, Laíse Capelasso da Silva et al. · Frontiers in Chemistry | 25 Sep 2020 | 624 |
| 26 | SOCS regulation of the JAK/STAT signalling pathway Ben A. Croker, Hiu Kiu, Sandra E. Nicholson · Seminars in Cell and Developmental Biology | 31 Jul 2008 | 621 |
| 27 | The Jak-STAT pathway Kazunori Imada, Warren J. Leonard · Molecular Immunology | 2000 | 616 |
| 28 | Negative Regulation of Cytokine Signaling Pathways Hideo Yasukawa, Atsuo T. Sasaki, Akihiko Yoshimura · Annual Review of Immunology | Apr 2000 | 610 |
| 29 | Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice Maciej Kujawski, Marcin T. Kortylewski, Heehyoung Lee et al. · Journal of Clinical Investigation | 4 Sep 2008 | 588 |
| 30 | Prognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysis Jiaxing Zhang, Song Wu, Zhenhua Chen et al. · The Lancet Oncology | 12 Nov 2013 | 575 |
| 31 | Mouse Chimæras Developed from Fused Eggs ANDRZEJ K. TARKOWSKI · Nature | Jun 1961 | 568 |
| 32 | Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Linda B. Mora, Ralf Buettner, John D. Seigne et al. · PubMed | 15 Nov 2002 | 535 |
| 33 | B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes. Martin Lotz, Frank Robert Jirik, Panagiotis S. Kabouridis et al. · The Journal of Experimental Medicine | Mar 1988 | 534 |
| 34 | Serotonin Content of Some Mammalian Tissues and Urine and a Method for Its Determination Betty M. Twarog, Irvine H. Page · American Journal of Physiology-Legacy Content | 30 Sep 1953 | 524 |
| 35 | Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro. Jennifer Rubin Grandis, Stephanie D. Drenning, Anutosh Chakraborty et al. · Journal of Clinical Investigation | Oct 1998 | 510 |
| 36 | Gigantism in mice lacking suppressor of cytokine signalling-2 Donald Metcalf, Christopher J. Greenhalgh, Elizabeth M. Viney et al. · Nature | Jun 2000 | 510 |
| 37 | Cloning and Characterization of IL-10-Related T Cell-Derived Inducible Factor (IL-TIF), a Novel Cytokine Structurally Related to IL-10 and Inducible by IL-9 Laure Dumoutier, Jamila Louahed, Jean‐Christophe Renauld · The Journal of Immunology | Feb 2000 | 503 |
| 38 | Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens. D. P. McDonnell, David L. Clemm, Thomas W. Hermann et al. · Molecular Endocrinology | Jun 1995 | 503 |
| 39 | Serum Osteoprotegerin Levels Are Associated With the Presence and Severity of Coronary Artery Disease Shuichi Jono, Yuji Ikari, Atsushi Shioi et al. · Circulation | 3 Sep 2002 | 492 |
| 40 | IL-10 inhibits human T cell proliferation and IL-2 production K Taga, Giovanna Tosato · The Journal of Immunology | Feb 1992 | 489 |
| 41 | The genus Epimedium: An ethnopharmacological and phytochemical review Huiping Ma, Xirui He, Yan Hui Yang et al. · Journal of Ethnopharmacology | 6 Jan 2011 | 488 |
| 42 | Interleukin-6 (IL-6)—A molecule with both beneficial and destructive potentials Reto A. Gadient, U. Otten · Progress in Neurobiology | Aug 1997 | 484 |
| 43 | Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling Robert C. Clarke, Minetta C. Liu, Kerrie B. Bouker et al. · Oncogene | 20 Oct 2003 | 481 |
| 44 | Scutellaria baicalensis Georgi. (Lamiaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology Tian-Tian Zhao, Hailong Tang, Long Xie et al. · Journal of Pharmacy and Pharmacology | 25 Jun 2019 | 480 |
| 45 | Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130 Sandra E. Nicholson, David Peter De Souza, Louis Fabri et al. · Proceedings of the National Academy of Sciences | 30 May 2000 | 466 |
| 46 | Hyperactivation of STAT3 Is Involved in Abnormal Differentiation of Dendritic Cells in Cancer Yulia Nefedova, Mei Huang, Sergei A. Kusmartsev et al. · The Journal of Immunology | 2004 | 463 |
| 47 | SOCS: physiological suppressors of cytokine signaling Danielle L. Krebs, Douglas J. Hilton · Journal of Cell Science | 15 Aug 2000 | 461 |
| 48 | LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer Xiangyang Xue, Yeqing Angela Yang, Aihua Zhang et al. · Oncogene | 14 Sep 2015 | 453 |
| 49 | Phosphotyrosyl Peptides Block Stat3-mediated DNA Binding Activity, Gene Regulation, and Cell Transformation James Turkson, Declan Ryan, Joon S. Kim et al. · Journal of Biological Chemistry | Nov 2001 | 448 |
| 50 | Inhibitors of Cytokine Signal Transduction Samuel Wormald, Douglas J. Hilton · Journal of Biological Chemistry | 2004 | 442 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.