Most cited papers in melanin and skin pigmentation
What are the most cited papers in melanin and skin pigmentation?
The most cited paper in melanin and skin pigmentation is "A biomarker that identifies senescent human cells in culture and in aging skin in vivo." (Goberdhan P. Dimri, X Lee, George Basile et al., 1995), with 7,565 citations. Next come "Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains" (3,039) and "Distinct Sets of Genetic Alterations in Melanoma" (2,732).
Showing 50 of 100 papers. Every paper with more than 728 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences | 26 Sep 1995 | 7,565 |
| 2 | Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains Patrick L. McGeer, Shigeru Itagaki, Barry E. Boyes et al. · Neurology | Aug 1988 | 3,039 |
| 3 | Distinct Sets of Genetic Alterations in Melanoma John A. Curtin, Jane Fridlyand, Toshiro Kageshita et al. · New England Journal of Medicine | 16 Nov 2005 | 2,732 |
| 4 | Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal Stanley Cohen · Journal of Biological Chemistry | May 1962 | 2,204 |
| 5 | BRAFE600-associated senescence-like cell cycle arrest of human naevi Chrysiis Michaloglou, Liesbeth C.W. Vredeveld, Marı́a S. Soengas et al. · Nature | Aug 2005 | 2,159 |
| 6 | Tyrosine Hydroxylase Toshiharu Nagatsu, Morton H. Levitt, Sidney Udenfriend · Journal of Biological Chemistry | Sep 1964 | 2,062 |
| 7 | Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation Andrzej T. Slominski, Desmond John Tobin, Shigeki Shibahara et al. · Physiological Reviews | 21 Sep 2004 | 2,030 |
| 8 | UV Radiation and the Skin John August D'Orazio, Stuart Gordon Jarrett, Alexandra Amaro-Ortiz et al. · International Journal of Molecular Sciences | 7 Jun 2013 | 1,979 |
| 9 | Role of melanocortinergic neurons in feeding and the agouti obesity syndrome Wei Fan, Bruce A. Boston, Robert A. Kesterson et al. · Nature | 1997 | 1,922 |
| 10 | Highly Recurrent TERT Promoter Mutations in Human Melanoma Franklin W. Huang, Eran Hodis, Mary Jue Xu et al. · Science | 24 Jan 2013 | 1,867 |
| 11 | Calcium regulation of growth and differentiation of mouse epidermal cells in culture Henry Hennings, Delores Michael, Christina Cheng et al. · Cell | 1980 | 1,822 |
| 12 | Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans Heiko Krude, Heike Biebermann, Werner A. P. Luck et al. · Nature Genetics | Jun 1998 | 1,741 |
| 13 | The Protective Role of Melanin Against UV Damage in Human Skin † Michaela Brenner, Vincent J. Hearing · Photochemistry and Photobiology | 16 Nov 2007 | 1,722 |
| 14 | Kinetic studies of pigment synthesis by non‐sulfur purple bacteria Germaine Cohen-Bazire, William R. Sistrom, Roger Y. Stanier · Journal of Cellular and Comparative Physiology | Feb 1957 | 1,622 |
| 15 | Anatomy and regulation of the central melanocortin system Roger D. Cone · Nature Neuroscience | 26 Apr 2005 | 1,586 |
| 16 | Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma Levi A. Garraway, Hans R. Widlund, Mark Andrew Rubin et al. · Nature | Jul 2005 | 1,560 |
| 17 | An Updated Review of Tyrosinase Inhibitors Te‐Sheng Chang · International Journal of Molecular Sciences | 26 May 2009 | 1,555 |
| 18 | Aromatic Amino Acids and Modification of Parkinsonism George C. Cotzias, Melvin H. Van Woert, Lewis M. Schiffer · New England Journal of Medicine | 16 Feb 1967 | 1,499 |
| 19 | Melanoma biology and new targeted therapy Vanessa C. Gray‐Schopfer, Claudia Wellbrock, Richard Marais · Nature | 21 Feb 2007 | 1,397 |
| 20 | Melanocyte biology and skin pigmentation Jennifer Y. Lin, David E. Fisher · Nature | Feb 2007 | 1,391 |
| 21 | Melanoma Arlo J. Miller, Martín C. Mihm · New England Journal of Medicine | 6 Jul 2006 | 1,347 |
| 22 | The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene E N Geissler, Melanie A. Ryan, David E. Housman · Cell | Oct 1988 | 1,326 |
| 23 | Toxic effects of ultraviolet radiation on the skin Yasuhiro Matsumura, Honnavara N. Ananthaswamy · Toxicology and Applied Pharmacology | 11 Dec 2003 | 1,274 |
| 24 | Tyrosinase: a comprehensive review of its mechanism Álvaro Sánchez‐Ferrer, José Neptuno Rodríguez‐López, Francisco Garcı́a-Cánovas et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology | Feb 1995 | 1,245 |
| 25 | The evolution of human skin coloration Nina G. Jablonski, George Chaplin · Journal of Human Evolution | Jul 2000 | 1,237 |
| 26 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma Michael O. Krauthammer et al. · Nature Genetics | 29 Jul 2012 | 1,221 |
| 27 | Molecular regulation of stem cell quiescence Tom H. Cheung, Thomas A. Rando · Nature Reviews Molecular Cell Biology | 23 May 2013 | 1,188 |
| 28 | MITF: master regulator of melanocyte development and melanoma oncogene Carmit Levy, Mehdi Khaled, David E. Fisher · Trends in Molecular Medicine | 9 Aug 2006 | 1,182 |
| 29 | Review: Ultraviolet radiation and skin cancer Deevya L. Narayanan, Rao N. Saladi, JOSHUA L. FOX · International Journal of Dermatology | 30 Aug 2010 | 1,182 |
| 30 | Human Keratinocytes That Express hTERT and Also Bypass a p16 INK4a -Enforced Mechanism That Limits Life Span Become Immortal yet Retain Normal Growth and Differentiation Characteristics Mark Andrew Dickson, William C. Hahn, Yasushi Ino et al. · Molecular and Cellular Biology | Feb 2000 | 1,122 |
| 31 | Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein Colin A. Hodgkinson, Karen J. Moore, Atsuo Nakayama et al. · Cell | Jul 1993 | 1,111 |
| 32 | Role of Matrix Metalloproteinases in Photoaging and Photocarcinogenesis Pavida Pittayapruek, Jitlada Meephansan, Ornicha Prapapan et al. · International Journal of Molecular Sciences | 2 Jun 2016 | 1,103 |
| 33 | Oxidative Pathways for Catecholamines in the Genesis of Neuromelanin and Cytotoxic Quinones Doyle G. Graham · Molecular Pharmacology | Jul 1978 | 1,102 |
| 34 | Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms Joi A. Nichols, Santosh K. Katiyar · Archives of Dermatological Research | 6 Nov 2009 | 1,100 |
| 35 | Acne vulgaris Hywel C Williams, Robert Paul Dellavalle, Sarah E. Garner · The Lancet | 31 Aug 2011 | 1,098 |
| 36 | Oxidative Stress in the Pathogenesis of Skin Disease David R. Bickers, Mohammad S. Athar · Journal of Investigative Dermatology | 16 Nov 2006 | 1,093 |
| 37 | The Genetic Evolution of Melanoma from Precursor Lesions Alan Hunter Shain, Iwei Yeh, Ivanka Kovalyshyn et al. · New England Journal of Medicine | 11 Nov 2015 | 1,091 |
| 38 | Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor Dongsi Lu, Derril H. Willard, Indravadan R. Patel et al. · Nature | Oct 1994 | 1,086 |
| 39 | A comprehensive review on tyrosinase inhibitors Samaneh Zolghadri, Asieh Bahrami, Mahmud Tareq Hassan Khan et al. · Journal of Enzyme Inhibition and Medicinal Chemistry | 2019 | 1,081 |
| 40 | Signaling Pathways in Melanogenesis Stacey Ann N. D’mello, Graeme J. Finlay, Bruce C. Baguley et al. · International Journal of Molecular Sciences | 15 Jul 2016 | 1,080 |
| 41 | SLC24A5, a Putative Cation Exchanger, Affects Pigmentation in Zebrafish and Humans Rebecca L. Lamason et al. · Science | 15 Dec 2005 | 1,076 |
| 42 | Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future Y.-J. Kim, Hiroshi Uyama · Cellular and Molecular Life Sciences | 15 May 2005 | 1,067 |
| 43 | Oxidative Stress in Aging Human Skin Mark Rinnerthaler, Johannes Bischof, Maria Karolin Streubel et al. · Biomolecules | 21 Apr 2015 | 1,054 |
| 44 | Structure of Polydopamine: A Never-Ending Story? Jürgen Liebscher, Radosław Mrówczyński, Holger A. Scheidt et al. · Langmuir | 22 Jul 2013 | 1,054 |
| 45 | The physical and chemical properties of eumelanin Paul Meredith, Tadeusz Sarna · Pigment Cell Research | 20 Oct 2006 | 1,041 |
| 46 | Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin Linda R. Yaswen, Nicole L. Diehl, Miles B. Brennan et al. · Nature Medicine | Sep 1999 | 1,028 |
| 47 | Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Sven‐Erik Dahlén, J Björk, Per Hedqvist et al. · Proceedings of the National Academy of Sciences | Jun 1981 | 1,027 |
| 48 | Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice Kiminori Hosoda, Robert E. Hammer, James A. Richardson et al. · Cell | Dec 1994 | 1,016 |
| 49 | Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans Paloma Valverde, Eugene Healy, Ian J. Jackson et al. · Nature Genetics | Nov 1995 | 1,013 |
| 50 | Laccases: a never-ending story Paola Giardina, Vincenza Faraco, Cinzia Pezzella et al. · Cellular and Molecular Life Sciences | 21 Oct 2009 | 1,005 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.