Most cited papers in Metabolomics and Mass Spectrometry Studies
What are the most cited papers in Metabolomics and Mass Spectrometry Studies?
The most cited paper in Metabolomics and Mass Spectrometry Studies is "Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction" (Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi, 1979), with 29,425 citations. Next come "Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2" (25,165) and "Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents" (24,756).
Showing 50 of 98 papers. Every paper with more than 2,568 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi · Analytical Biochemistry | Jun 1979 | 29,425 |
| 2 | Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 Evan K Bolyen et al. · Nature Biotechnology | 24 Jul 2019 | 25,165 |
| 3 | Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents Vernon L. Singleton, Joseph A. Rossi · American Journal of Enology and Viticulture | 1965 | 24,756 |
| 4 | Metagenomic biomarker discovery and explanation Nicola Segata, Jacques Izard, Levi D. Waldron et al. · Genome biology | 24 Jun 2011 | 17,136 |
| 5 | NMRPipe: A multidimensional spectral processing system based on UNIX pipes Frank Delaglio, Stephan Grzesiek, Geerten W. Vuister et al. · Journal of Biomolecular NMR | Nov 1995 | 16,465 |
| 6 | MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification Jürgen Cox, Matthias Mann · Nature Biotechnology | 23 Nov 2008 | 15,998 |
| 7 | Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. Laurent Excoffier, Peter E. Smouse, Joseph M. Quattro · Genetics | Jun 1992 | 14,110 |
| 8 | clusterProfiler 4.0: A universal enrichment tool for interpreting omics data Tianzhi Wu, Erqiang Hu, Shuangbin Xu et al. · The Innovation | Jul 2021 | 13,194 |
| 9 | The Perseus computational platform for comprehensive analysis of (prote)omics data Stefka Tyanova, Tikira Temu, Pavel G. Sinitcyn et al. · Nature Methods | 27 Jun 2016 | 9,121 |
| 10 | Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels Andrej Shevchenko, Matthias S. Wilm, Ole Vorm et al. · Analytical Chemistry | Mar 1996 | 9,120 |
| 11 | DrugBank 5.0: a major update to the DrugBank database for 2018 David Scott Wishart et al. · Nucleic Acids Research | 4 Nov 2017 | 9,014 |
| 12 | Protein Identification and Analysis Tools on the ExPASy Server Elisabeth Gasteiger, Christine Hoogland, Alexandre Gattiker et al. · Humana Press eBooks | 2005 | 8,916 |
| 13 | Universal sample preparation method for proteome analysis Jacek R. Wiśniewski, Alexandre Zougman, Nagarjuna Nagaraj et al. · Nature Methods | 19 Apr 2009 | 8,878 |
| 14 | THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM Richard J. Havel, Howard A. Eder, Joseph H. Bragdon · Journal of Clinical Investigation | Sep 1955 | 8,822 |
| 15 | A simplification of the protein assay method of Lowry et al. which is more generally applicable Gary L. Peterson · Analytical Biochemistry | Dec 1977 | 8,575 |
| 16 | Probability-based protein identification by searching sequence databases using mass spectrometry data David N. Perkins, Darryl Pappin, David M. Creasy et al. · Electrophoresis | Dec 1999 | 8,335 |
| 17 | The PRIDE database and related tools and resources in 2019: improving support for quantification data Yasset Pérez‐Riverol et al. · Nucleic Acids Research | 22 Oct 2018 | 7,481 |
| 18 | A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY | Apr 1999 | 7,022 |
| 19 | PICRUSt2 for prediction of metagenome functions Gavin M. Douglas, Vincent J. Maffei, Jesse Zaneveld et al. · Nature Biotechnology | Jun 2020 | 7,006 |
| 20 | A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples Mary Ann K. Markwell, Suzanne M. Haas, LORAN L. BIEBER et al. · Analytical Biochemistry | Jun 1978 | 6,504 |
| 21 | The Human Microbiome Project Peter James Turnbaugh, Ruth E. Ley, Micah Hamady et al. · Nature | 17 Oct 2007 | 6,235 |
| 22 | Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease Zeneng Wang, Elizabeth Klipfell, Brian J. Bennett et al. · Nature | Apr 2011 | 5,702 |
| 23 | PubChem Substance and Compound databases Sunghwan Kim, Paul A Thiessen, Evan Bolton et al. · Nucleic Acids Research | 22 Sep 2015 | 5,614 |
| 24 | Quality control and preprocessing of metagenomic datasets Robert Schmieder, Robert Alan Edwards · Bioinformatics | 28 Jan 2011 | 5,477 |
| 25 | XCMS: Processing Mass Spectrometry Data for Metabolite Profiling Using Nonlinear Peak Alignment, Matching, and Identification Colin A. Smith, Elizabeth J. Want, Grace O’Maille et al. · Analytical Chemistry | 7 Jan 2006 | 5,419 |
| 26 | An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea Daniel T. McDonald, Morgan N. Price, Julia K. Goodrich et al. · The ISME Journal | Dec 2011 | 5,371 |
| 27 | Proposed minimum reporting standards for chemical analysis Lloyd W. Sumner et al. · Metabolomics | 11 Sep 2007 | 5,359 |
| 28 | The MaxQuant computational platform for mass spectrometry-based shotgun proteomics Stefka Tyanova, Tikira Temu, Jüergen Cox · Nature Protocols | 27 Oct 2016 | 5,351 |
| 29 | In-gel digestion for mass spectrometric characterization of proteins and proteomes Andrej Shevchenko, Henrik Tomas, J. Havli et al. · Nature Protocols | Dec 2006 | 5,186 |
| 30 | How good are my data and what is the resolution? Philip Rainsford Evans, Garib N. Murshudov · Acta Crystallographica Section D Biological Crystallography | 12 Jun 2013 | 5,147 |
| 31 | Skyline: an open source document editor for creating and analyzing targeted proteomics experiments Brendan MacLean, Daniela M. Tomazela, Nicholas Shulman et al. · Bioinformatics | 9 Feb 2010 | 5,063 |
| 32 | A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry Alexey I. Nesvizhskii, Andrew Keller, Eugene Kolker et al. · Analytical Chemistry | 15 Jul 2003 | 5,023 |
| 33 | Empirical Statistical Model To Estimate the Accuracy of Peptide Identifications Made by MS/MS and Database Search Andrew Keller, Alexey I. Nesvizhskii, Eugene Kolker et al. · Analytical Chemistry | 12 Sep 2002 | 5,013 |
| 34 | Why do cancers have high aerobic glycolysis? Robert A. Gatenby, Robert J. Gillies · Nature reviews. Cancer | Nov 2004 | 4,841 |
| 35 | Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking Mingxun Wang et al. · Nature Biotechnology | Aug 2016 | 4,812 |
| 36 | Metagenomic Analysis of the Human Distal Gut Microbiome Steven R. Gill, Mihai Pop, Robert T. DeBoy et al. · Science | Jun 2006 | 4,702 |
| 37 | A cross-platform toolkit for mass spectrometry and proteomics Matthew Chambers et al. · Nature Biotechnology | Oct 2012 | 4,457 |
| 38 | Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis Robert Koeth et al. · Nature Medicine | 7 Apr 2013 | 4,454 |
| 39 | MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights Zhiqiang Pang, Jasmine Chong, Guangyan Zhou et al. · Nucleic Acids Research | 28 Apr 2021 | 4,235 |
| 40 | Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry Joshua Eric Elias, Steven P. Gygi · Nature Methods | 27 Feb 2007 | 4,142 |
| 41 | PubChem in 2021: new data content and improved web interfaces Sunghwan Kim, Jie Chen, Tiejun Cheng et al. · Nucleic Acids Research | 12 Oct 2020 | 4,131 |
| 42 | Functional cartography of complex metabolic networks Roger Guimerà, Luı́s A. Nunes Amaral · Nature | Feb 2005 | 4,113 |
| 43 | mixOmics: An R package for ‘omics feature selection and multiple data integration Florian Rohart, Benoît Gautier, Amrit Singh et al. · PLoS Computational Biology | 3 Nov 2017 | 4,107 |
| 44 | ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap Tauno Metsalu, Jaak Vilo · Nucleic Acids Research | 12 May 2015 | 4,030 |
| 45 | MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data Tomáš Pluskal, Sandra D. Castillo, Alejandro Villar‐Briones et al. · BMC Bioinformatics | 23 Jul 2010 | 4,019 |
| 46 | 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data Jeremy Kirk Nicholson, John C. Lindon, Elaine C. Holmes · Xenobiotica | 1999 | 3,918 |
| 47 | MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis Jasmine Chong, Othman Soufan, Carin Li et al. · Nucleic Acids Research | 13 Apr 2018 | 3,876 |
| 48 | Estimation of metabolite concentrations from localized in vivo proton NMR spectra Stephen W. Provencher · Magnetic Resonance in Medicine | Dec 1993 | 3,732 |
| 49 | 2016 update of the PRIDE database and its related tools Juan Antonio Vizcaíno, Attila Csordás, Noemí del‐Toro et al. · Nucleic Acids Research | 2 Nov 2015 | 3,695 |
| 50 | HMDB 4.0: the human metabolome database for 2018 David Scott Wishart et al. · Nucleic Acids Research | 23 Oct 2017 | 3,621 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.