Most cited papers in Microbial metabolism and enzyme function
What are the most cited papers in Microbial metabolism and enzyme function?
The most cited paper in Microbial metabolism and enzyme function is "Alpha-lipoic acid as a biological antioxidant" (Lester Packer, Eric H. Witt, Hans Tritschler, 1995), with 1,981 citations. Next come "Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial" (1,861) and "Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: new metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes" (1,780).
Showing 50 of 97 papers. Every paper with more than 502 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Alpha-lipoic acid as a biological antioxidant Lester Packer, Eric H. Witt, Hans Tritschler · Free Radical Biology and Medicine | Aug 1995 | 1,981 |
| 2 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial Brian I. Rini et al. · The Lancet | 4 Nov 2011 | 1,861 |
| 3 | Growth of Rhodococcus sp. strain BCP1 on gaseous n-alkanes: new metabolic insights and transcriptional analysis of two soluble di-iron monooxygenase genes Martina Cappelletti, Alessandro Presentato, Giorgio Milazzo et al. · Frontiers in Microbiology | 12 May 2015 | 1,780 |
| 4 | Methanotrophic bacteria R S Hanson, Timothy Hanson · Microbiological Reviews | Jun 1996 | 1,723 |
| 5 | Enrichment, Isolation and Some Properties of Methane-utilizing Bacteria Roger Whittenbury, K. C. Phillips, JOHN FREDERICK WILKINSON · Journal of General Microbiology | May 1970 | 1,483 |
| 6 | Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. Abraham Abuchowski, Theo Van Es, Nicholas C. Palczuk et al. · Journal of Biological Chemistry | Jun 1977 | 1,363 |
| 7 | Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation Stephen W. Ragsdale, Elizabeth A. Pierce · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 7 Sep 2008 | 1,352 |
| 8 | Structure and Spectroscopy of Copper−Dioxygen Complexes Liviu M. Mirica, Xavier Ottenwaelder, T. Daniel P. Stack · Chemical Reviews | 29 Jan 2004 | 1,339 |
| 9 | Oxidative Stress in Atherosclerosis Ajoe John Kattoor, Naga Venkata K. Pothineni, Deepak R. Palagiri et al. · Current Atherosclerosis Reports | 18 Sep 2017 | 1,271 |
| 10 | Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche Janine Terra Erler, Kevin L. Bennewith, Thomas R. Cox et al. · Cancer Cell | 2009 | 1,242 |
| 11 | Proline Mechanisms of Stress Survival Xinwen Liang, Lu Zhang, Sathish Kumar Natarajan et al. · Antioxidants and Redox Signaling | 15 Apr 2013 | 1,227 |
| 12 | The roles of acetotrophic and hydrogenotrophic methanogens during anaerobic conversion of biomass to methane: a review Burak Demirel, Paul Scherer · Reviews in Environmental Science and Bio/Technology | 30 Jan 2008 | 1,199 |
| 13 | Biochemistry of methanogenesis: a tribute to Marjory Stephenson:1998 Marjory Stephenson Prize Lecture Rudolf Kurt Thauer · Microbiology | Sep 1998 | 1,133 |
| 14 | Applications of the acetylene-ethylene assay for measurement of nitrogen fixation Ralph W. F. Hardy, Richard C. Burns, R. D. Holsten · Soil Biology and Biochemistry | 1973 | 1,055 |
| 15 | The role of collagen in bone strength S. Viguet‐Carrin, Patrick Garnero, Pierre Dominique Delmas · Osteoporosis International | 8 Dec 2005 | 1,039 |
| 16 | An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR) Jennifer L. Reed, Thuy D. Vo, Christophe H. Schilling et al. · Genome biology | 28 Aug 2003 | 1,032 |
| 17 | Non-Heme Fe(IV)–Oxo Intermediates Carsten Krebs, Danica Galonić Fujimori, Christopher T. Walsh et al. · Accounts of Chemical Research | 2 Jun 2007 | 1,012 |
| 18 | Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell Herbert M. Kagan, Wande Li · Journal of Cellular Biochemistry | 27 Nov 2002 | 956 |
| 19 | Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane Amy C. Rosenzweig, Christin Frederick, Stephen J. Lippard et al. · Nature | Dec 1993 | 935 |
| 20 | Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation. Niels Borregaard, Jeanne M. Heiple, Elizabeth Radin Simons et al. · The Journal of Cell Biology | Jul 1983 | 926 |
| 21 | Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. Douglass M. Bradham, Atsuyuki Igarashi, Robert Lyman Potter et al. · The Journal of Cell Biology | 15 Sep 1991 | 893 |
| 22 | Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment Vivian Barry-Hamilton et al. · Nature Medicine | Sep 2010 | 872 |
| 23 | Anaerobic oxidation of ammonium is a biologically mediated process Astrid A. van de Graaf, A. Mulder, Peter de Bruijn et al. · Applied and Environmental Microbiology | Apr 1995 | 853 |
| 24 | Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates Judith Pollock Klinman · Chemical Reviews | 1996 | 840 |
| 25 | Notch signaling mediates hypoxia-induced tumor cell migration and invasion Cecilia Sahlgren, Maria V. Gustafsson, Shaobo Jin et al. · Proceedings of the National Academy of Sciences | 22 Apr 2008 | 838 |
| 26 | The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. Barry M. Gumbiner, Bruce R. Stevenson, Ashley D Grimaldi · The Journal of Cell Biology | Oct 1988 | 807 |
| 27 | Influence of nitrogen fertilization on methane uptake in temperate forest soils Paul A. Steudler, Richard D. Bowden, Jerry M. Melillo et al. · Nature | Sep 1989 | 799 |
| 28 | Evidence that participate methane monooxygenase and ammonia monooxygenase may be evolutionarily related Andrew J. Holmes, Andria M. Costello, Mary E. Lidstrom et al. · FEMS Microbiology Letters | Oct 1995 | 798 |
| 29 | Methanotrophs and copper Jeremy D. Semrau, Alan A. DiSpirito, Sukhwan Yoon · FEMS Microbiology Reviews | 30 Jan 2010 | 773 |
| 30 | Quinone chemistry and toxicity Terrence J. Monks, Robert P. Hanzlik, Gerald M. Cohen et al. · Toxicology and Applied Pharmacology | 1992 | 764 |
| 31 | Microbial Ecology of Methanogens and Methanotrophs Ralf Conrad · Advances in agronomy | 2007 | 763 |
| 32 | Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Masayuki Ozawa, Martin Ringwald, Rolf Kemler · Proceedings of the National Academy of Sciences | Jun 1990 | 752 |
| 33 | Carrageenan-Induced Paw Edema in the Rat and Mouse Christopher J. Morris · Humana Press eBooks | 15 Nov 2003 | 742 |
| 34 | The First Direct Characterization of a High-Valent Iron Intermediate in the Reaction of an α-Ketoglutarate-Dependent Dioxygenase: A High-Spin Fe(IV) Complex in Taurine/α-Ketoglutarate Dioxygenase (TauD) from Escherichia coli John C. Price, Eric W. Barr, Bhramara Tirupati et al. · Biochemistry | 28 May 2003 | 739 |
| 35 | cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Allan W. Bach, N C Lan, Dana L. Johnson et al. · Proceedings of the National Academy of Sciences | Jul 1988 | 729 |
| 36 | Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Volkhard Lindner, Michael A. Reidy · Proceedings of the National Academy of Sciences | May 1991 | 719 |
| 37 | Single Cell Protein—State-of-the-Art, Industrial Landscape and Patents 2001–2016 Anneli Ritala, Suvi Tuulikki Häkkinen, Mervi H. Toivari et al. · Frontiers in Microbiology | 13 Oct 2017 | 716 |
| 38 | A new acid-tolerant nitrogen-fixing bacterium associated with sugarcane V. A. Cavalcante, Johanna Döbereiner · Plant and Soil | May 1988 | 713 |
| 39 | Diversity and Structure of the Methanogenic Community in Anoxic Rice Paddy Soil Microcosms as Examined by Cultivation and Direct 16S rRNA Gene Sequence Retrieval Regine Großkopf, Peter H. Janssen, Werner Liesack · Applied and Environmental Microbiology | Mar 1998 | 709 |
| 40 | Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts Paul John Thornalley · Archives of Biochemistry and Biophysics | 16 Sep 2003 | 681 |
| 41 | Functions of amine oxidases in plant development and defence Alessandra Cona, Giuseppina Rea, Riccardo Angelini et al. · Trends in Plant Science | 10 Jan 2006 | 671 |
| 42 | Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane Raquel L. Lieberman, Amy C. Rosenzweig · Nature | 26 Jan 2005 | 670 |
| 43 | Elastic fiber homeostasis requires lysyl oxidase–like 1 protein Xiaoqing Liu, Yun Fu Zhao, Jiangang Gao et al. · Nature Genetics | 25 Jan 2004 | 663 |
| 44 | A New Redox Cofactor in Eukaryotic Enzymes: 6-Hydroxydopa at the Active Site of Bovine Serum Amine Oxidase Susan M. Janes, David Mu, David E. Wemmer et al. · Science | 25 May 1990 | 660 |
| 45 | Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins Maarten Merkx, Daniel A. Kopp, Matthew Howard Sazinsky et al. · Angewandte Chemie International Edition | 3 Aug 2001 | 648 |
| 46 | Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities Lynn M. Boyden et al. · Nature | 20 Jan 2012 | 644 |
| 47 | Novel Mechanism for Endothelial Dysfunction Akira Ito, Philip S. Tsao, Shanthi Adimoolam et al. · Circulation | 22 Jun 1999 | 641 |
| 48 | Microbial Production of Hydrogen: An Overview Rabindranath Nandi, Souvik Sengupta · Critical Reviews in Microbiology | 1998 | 639 |
| 49 | Toluene Degradation by Pseudomonas putida F1 Gerben J. Zylstra, D T Gibson · Journal of Biological Chemistry | Sep 1989 | 633 |
| 50 | An evolving view of methane metabolism in the Archaea Paul N. Evans, Joel A. Boyd, Andy O Leu et al. · Nature Reviews Microbiology | 21 Jan 2019 | 631 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.