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Most cited papers in Microfluidic and Capillary Electrophoresis Applications

Microfluidic and Capillary Electrophoresis Applications

What are the most cited papers in Microfluidic and Capillary Electrophoresis Applications?

The most cited paper in Microfluidic and Capillary Electrophoresis Applications is "High resolution two-dimensional electrophoresis of proteins." (Patrick H. O’Farrell, 1975), with 19,391 citations. Next come "DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*" (18,971) and "NMRPipe: A multidimensional spectral processing system based on UNIX pipes" (16,465).

Showing 50 of 99 papers. Every paper with more than 1,225 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 High resolution two-dimensional electrophoresis of proteins. Patrick H. O’Farrell · Journal of Biological Chemistry Open access May 1975 19,391
2 DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS* Baruch J. Davis · Annals of the New York Academy of Sciences Dec 1964 18,971
3 NMRPipe: A multidimensional spectral processing system based on UNIX pipes Frank Delaglio, Stephan Grzesiek, Geerten W. Vuister et al. · Journal of Biomolecular NMR Nov 1995 16,465
4 Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa Hermann Schägger, Gebhard von Jagow · Analytical Biochemistry Nov 1987 11,542
5 The origins and the future of microfluidics George M. Whitesides · Nature Jul 2006 9,641
6 Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities Brent Ewing, Phil Green · Genome Research Open access Mar 1998 5,578
7 Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane) David C. Duffy, J. Cooper McDonald, Olivier J. A. Schueller et al. · Analytical Chemistry 24 Oct 1998 5,316
8 SOFT LITHOGRAPHY Younan Xia, George M. Whitesides · Annual Review of Materials Science Aug 1998 4,610
9 Microfluidics: Fluid physics at the nanoliter scale Todd M. Squires, Stephen R. Quake · Reviews of Modern Physics 6 Oct 2005 4,383
10 Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography Marc Unger, Hou-Pu Chou, Todd Thorsen et al. · Science 7 Apr 2000 4,036
11 A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs Philip L. Ritger, Nikolaos A. Peppas · Journal of Controlled Release Jun 1987 3,824
12 Engineering Flows in Small Devices: Microfluidics Toward a Lab-on-a-Chip Howard A. Stone, Abraham Duncan Stroock, Armand Ajdari · Annual Review of Fluid Mechanics Review 7 Apr 2003 3,655
13 Isolation of rare circulating tumour cells in cancer patients by microchip technology Sunitha Nagrath, Lecia Van Dam Sequist, Shyamala Maheswaran et al. · Nature Open access Dec 2007 3,572
14 High resolution two-dimensional electrophoresis of basic as well as acidic proteins Patricia Z. O’Farrell, Howard M. Goodman, Patrick H. O’Farrell · Cell Dec 1977 3,541
15 Chaotic Mixer for Microchannels Abraham Duncan Stroock, Stephan K. W. Dertinger, Armand Ajdari et al. · Science 25 Jan 2002 3,431
16 Characterization of individual polynucleotide molecules using a membrane channel John J. Kasianowicz, Eric Brandin, Daniel Branton et al. · Proceedings of the National Academy of Sciences Open access 26 Nov 1996 3,401
17 Fluorometric Deoxyribonucleic Acid-Deoxyribonucleic Acid Hybridization in Microdilution Wells as an Alternative to Membrane Filter Hybridization in which Radioisotopes Are Used To Determine Genetic Relatedness among Bacterial Strains T. EZAKI, Yohey Hashimoto, Eiko Yabuuchi · International Journal of Systematic Bacteriology Jul 1989 3,269
18 Fabrication of microfluidic systems in poly(dimethylsiloxane) J. Cooper McDonald, David Cameron Duffy, Janelle R. Anderson et al. · Electrophoresis 2000 3,231
19 Bacterial Persistence as a Phenotypic Switch Nathalie Q. Balaban, Jack Merrin, Remy Chait et al. · Science 12 Aug 2004 3,114
20 Miniaturized total chemical analysis systems: A novel concept for chemical sensing A. Manz, N. Graber, H. Michael. Widmer · Sensors and Actuators B Chemical 1990 3,107
21 The present and future role of microfluidics in biomedical research Eric K. Sackmann, Anna L. Fulton, David J. Beebe · Nature Mar 2014 3,003
22 Enhancements and modifications of primer design program Primer3 Triinu Kõressaar, Maido Remm · Bioinformatics Open access 22 Mar 2007 2,721
23 Imprint of sub-25 nm vias and trenches in polymers Stephen Y. Chou, Peter R. Krauss, Preston J. Renstrom · Applied Physics Letters 20 Nov 1995 2,715
24 Droplet microfluidics Shia‐Yen Teh, Robert E. Lin, Lung-Hsin Hung et al. · Lab on a Chip 2008 2,704
25 Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices Jessamine Ng Lee, Cheolmin Park, George M. Whitesides · Analytical Chemistry 11 Oct 2003 2,619
26 The potential and challenges of nanopore sequencing Daniel Branton et al. · Nature Biotechnology Open access Oct 2008 2,585
27 Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose Jan Kyhse‐Andersen · Journal of Biochemical and Biophysical Methods Dec 1984 2,521
28 A pharmacokinetic analysis program (multi) for microcomputer. Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics Open access 1981 2,459
29 Poly(dimethylsiloxane) as a Material for Fabricating Microfluidic Devices J. Cooper McDonald, George M. Whitesides · Accounts of Chemical Research 24 Apr 2002 2,453
30 Soft lithography for micro- and nanoscale patterning Dong Qin, Younan Xia, George M. Whitesides · Nature Protocols Open access 18 Feb 2010 2,368
31 Molecular Imprinting in Cross‐Linked Materials with the Aid of Molecular Templates— A Way towards Artificial Antibodies Günter Wulff · Angewandte Chemie International Edition in English 15 Sep 1995 2,365
32 Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up Piotr Garstecki, Michael J. Fuerstman, Howard A. Stone et al. · Lab on a Chip 2006 2,325
33 Formation of dispersions using “flow focusing” in microchannels Shelley L. Anna, Nathalie Bontoux, Howard A. Stone · Applied Physics Letters 16 Jan 2003 2,286
34 Imprint Lithography with 25-Nanometer Resolution Stephen Y. Chou, Peter R. Krauss, Preston J. Renstrom · Science 5 Apr 1996 2,272
35 Molecularly Imprinted Polymers and Their Use in Biomimetic Sensors Karsten Haupt, Klaus Mosbach · Chemical Reviews Review 21 Jun 2000 2,270
36 Microfluidic Large-Scale Integration Todd Thorsen, Sebastian J. Maerkl, Stephen R. Quake · Science Open access 17 Oct 2002 2,245
37 Micro Total Analysis Systems. 1. Introduction, Theory, and Technology Darwin R. Reyes, Dimitri Iossifidis, Pierre-Alain Auroux et al. · Analytical Chemistry 17 May 2002 2,196
38 The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis UE Loening · Biochemical Journal Open access 1967 2,108
39 Cells on chips J. El-Ali, Peter Karl Sorger, Klavs F. Jensen · Nature 26 Jul 2006 2,095
40 Electrospray ion source. Another variation on the free-jet theme Masamichi Yamashita, John B. Fenn · The Journal of Physical Chemistry Sep 1984 2,071
41 Molecular Weight Determination of Protein-Dodecyl Sulfate Complexes by Gel Electrophoresis in a Discontinuous Buffer System David M. Neville · Journal of Biological Chemistry Open access Oct 1971 1,999
42 The Hitchhiker’s Guide to Flow Chemistry Matthew B. Plutschack, Bartholomäus Pieber, Kerry M. Gilmore et al. · Chemical Reviews Review Jun 2017 1,996
43 Transport phenomena in nanofluidics Reto B. Schoch, Jongyoon Han, Philippe Renaud · Reviews of Modern Physics Open access 17 Jul 2008 1,936
44 Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process Roman A. Zubarev, Neil L. Kelleher, Fred W. McLafferty · Journal of the American Chemical Society 24 Mar 1998 1,888
45 Analytical Properties of the Nanoelectrospray Ion Source Matthias S. Wilm, Matthias Mann · Analytical Chemistry 1996 1,877
46 Lab-on-a-chip: microfluidics in drug discovery Petra Stephanie Dittrich, A. Manz · Nature Reviews Drug Discovery Review Mar 2006 1,850
47 Reactions in Droplets in Microfluidic Channels Helen Song, Delai L. Chen, Rustem F. Ismagilov · Angewandte Chemie International Edition Open access 6 Nov 2006 1,848
48 A review of micropumps Daniel J. Laser, Juan Gabriel Santiago · Journal of Micromechanics and Microengineering 20 Apr 2004 1,841
49 Inkjet Printing for Materials and Devices Paul Calvert · Chemistry of Materials 12 Sep 2001 1,822
50 Studies in Newtonian Flow. II. The Dependence of the Viscosity of Liquids on Free-Space Arthur K. Doolittle · Journal of Applied Physics Dec 1951 1,822

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.