Most cited papers in Natural Products and Biological Research
What are the most cited papers in Natural Products and Biological Research?
The most cited paper in Natural Products and Biological Research is "Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels" (John R. Downs, Michael B. Clearfield, Stephen E. Weis et al., 1998), with 5,297 citations. Next come "Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis" (4,053) and "Pro-resolving lipid mediators are leads for resolution physiology" (3,047).
Showing 50 of 100 papers. Every paper with more than 232 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels John R. Downs, Michael B. Clearfield, Stephen E. Weis et al. · JAMA | 27 May 1998 | 5,297 |
| 2 | Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis Claire Bombardier, Loren Laine, Alise S. Reicin et al. · New England Journal of Medicine | 23 Nov 2000 | 4,053 |
| 3 | Pro-resolving lipid mediators are leads for resolution physiology Charles Nicholas Serhan · Nature | 3 Jun 2014 | 3,047 |
| 4 | A MODIFIED COLORIMETRIC METHOD FOR THE ESTIMATION OF N-ACETYLAMINO SUGARS José L. Reissig, Jack L. Strominger, Luis Federico Leloir · Journal of Biological Chemistry | Dec 1955 | 2,591 |
| 5 | Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials N Bhala · The Lancet | 29 May 2013 | 1,809 |
| 6 | Trans Fatty Acids and Cardiovascular Disease Dariush Mozaffarian, Mira Katan, Alberto Ascherio et al. · New England Journal of Medicine | 12 Apr 2006 | 1,774 |
| 7 | Rosmarinic acid Maike Petersen · Phytochemistry | 27 Dec 2002 | 1,239 |
| 8 | New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre? Anthony Fardet · Nutrition Research Reviews | Jun 2010 | 1,035 |
| 9 | Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk Stephen James Nicholls et al. · JAMA | 15 Nov 2020 | 1,028 |
| 10 | The Lipid Treatment Assessment Project (L-TAP) Thomas A. Pearson, Irene Laurora, Henry Chu et al. · Archives of Internal Medicine | 28 Feb 2000 | 1,016 |
| 11 | Sorghum phytochemicals and their potential impact on human health Joseph M. Awika, Lloyd W. Rooney · Phytochemistry | May 2004 | 979 |
| 12 | ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum. Akira Endo, Masao Kuroda, Yoshio Tsujita · The Journal of Antibiotics | 1976 | 957 |
| 13 | n–3 Fatty Acids and Cardiovascular Events after Myocardial Infarction Daan Kromhout, Erik J. Giltay, Johanna Marianne Geleijnse · New England Journal of Medicine | 7 Oct 2010 | 937 |
| 14 | Metabolism of highly unsaturated n-3 and n-6 fatty acids Howard W. Sprecher · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | Jul 2000 | 870 |
| 15 | Cyclooxygenase-1 and Cyclooxygenase-2 Selectivity of Widely Used Nonsteroidal Anti-Inflammatory Drugs Byron Cryer, Mark L. Feldman · The American Journal of Medicine | May 1998 | 770 |
| 16 | Reduction of Serum Cholesterol with Sitostanol-Ester Margarine in a Mildly Hypercholesterolemic Population Tatu A. Miettinen, Pekka Puska, Helena K. Gylling et al. · New England Journal of Medicine | 16 Nov 1995 | 745 |
| 17 | Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial Thomas J. Schnitzer, Gerd Rüdiger Burmester, Eduardo Mysler et al. · The Lancet | Aug 2004 | 704 |
| 18 | Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus The ASCEND Study Collaborative Group · New England Journal of Medicine | 26 Aug 2018 | 703 |
| 19 | Polyunsaturated fatty acids, hyperlipidemia, and thrombosis. Scott H. Goodnight, William Stephen Harris, Connor We et al. · Arteriosclerosis An Official Journal of the American Heart Association Inc | Mar 1982 | 684 |
| 20 | Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Diseases Carl J. Lavie, Richard V. Milani, Mandeep R. Mehra et al. · Journal of the American College of Cardiology | Aug 2009 | 641 |
| 21 | Novel food and non-food uses for sorghum and millets JOHN R. N. TAYLOR, Tilman J. Schober, Scott R. Bean · Journal of Cereal Science | 7 Sep 2006 | 607 |
| 22 | Beneficial effects of docosahexaenoic acid on cognition in age‐related cognitive decline Karin Yurko‐Mauro, Deanna McCarthy, Dror Rom et al. · Alzheimer s & Dementia | May 2010 | 575 |
| 23 | Antidiabetic Agents from Medicinal Plants Mankil Jung, Moonsoo Park, Hyun Lee et al. · Current Medicinal Chemistry | 28 Mar 2006 | 572 |
| 24 | Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hypercholesterolaemic subjects JA Weststrate, Gert W. Meijer · European Journal of Clinical Nutrition | May 1998 | 540 |
| 25 | Metabolism of polyunsaturated fatty acids and their toxicity to the microflora of the rumen Margarida R. G. Maia, L.C. Chaudhary, Lauren Figueres et al. · Antonie van Leeuwenhoek | 27 Oct 2006 | 532 |
| 26 | Characterisation of the double genome structure of modern sugarcane cultivars (Saccharum spp.) by molecular cytogenetics Angélique D’Hont, L. Grivet, Philippe Feldmann et al. · Molecular and General Genetics MGG | Mar 1996 | 510 |
| 27 | High‐throughput micro plate assays for screening flavonoid content and DPPH‐scavenging activity in sorghum bran and flour Thomas J. Herald, Priyadarshini Gadgil, Michael Tilley · Journal of the Science of Food and Agriculture | 14 Mar 2012 | 467 |
| 28 | Conjugated Linoleic Acid Content of Milk from Cows Fed Different Diets T.R. Dhiman, G.R. Anand, Larry D. Satter et al. · Journal of Dairy Science | Oct 1999 | 464 |
| 29 | Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo Hatice Hastürk, Alpdoğan Kantarcı, Emilie Goguet et al. · The Journal of Immunology | Nov 2007 | 462 |
| 30 | Pravastatin limitation of atherosclerosis in the coronary arteries (PLAC I): Reduction in atherosclerosis progression and clinical events Bertram Pitt, G.B.John Mancini, Stephen G. Ellis et al. · Journal of the American College of Cardiology | Nov 1995 | 429 |
| 31 | Tinospora cordifolia: One plant, many roles Shyamasree Ghosh, Soham Saha · Ancient Science of Life | 2012 | 409 |
| 32 | Eicosapentaenoic Acid Prevents LPS-Induced TNF-α Expression by Preventing NF-κB Activation Yan Zhao, Swati Joshi‐Barve, Shirish Barve et al. · Journal of the American College of Nutrition | Feb 2004 | 405 |
| 33 | A review on phytochemistry and therapeutic uses of Hibiscus sabdariffa L. Ghazala Riaz, Rajni Chopra · Biomedicine & Pharmacotherapy | 6 Apr 2018 | 392 |
| 34 | Sorghum ( Sorghum bicolor L.): Nutrients, bioactive compounds, and potential impact on human health Leandro de Morais Cardoso, Soraia Silva Pinheiro, Hércia Stampini Duarte Martino et al. · Critical Reviews in Food Science and Nutrition | 15 Apr 2015 | 381 |
| 35 | Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: Visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum Anthony H.M. Terpstra, Christopher J. H. Woodward, Francisco José Sánchez-Muniz · Analytical Biochemistry | Feb 1981 | 372 |
| 36 | Nonsteroidal Anti-Inflammatory Drugs: Adverse Effects and Their Prevention Harald E. Vonkeman, Mart A F J van de Laar · Seminars in Arthritis and Rheumatism | 28 Sep 2008 | 370 |
| 37 | Prevention of Fatal Arrhythmias in High-Risk Subjects by Fish Oil n-3 Fatty Acid Intake Alexander Leaf, Christine M. Albert, Mark E. Josephson et al. · Circulation | Nov 2005 | 367 |
| 38 | Heterogeneity of serum low density lipoproteins in normal human subjects. Mengyuan Shen, R.M. Krauss, F. T. Lindgren et al. · Journal of Lipid Research | Feb 1981 | 362 |
| 39 | The structure of an inhibitor of cholesterol biosynthesis isolated from barley. Asaf A. Qureshi, W. C. Burger, David M. Peterson et al. · Journal of Biological Chemistry | Aug 1986 | 360 |
| 40 | Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity John Lawrence Wallace, Adrian William Bak, Webb McKnight et al. · Gastroenterology | Jul 1998 | 348 |
| 41 | Resolvins, docosatrienes, and neuroprotectins, novel omega‐3‐derived mediators, and their endogenous aspirin‐triggered epimers Charles Nicholas Serhan, Makoto Arita, Song Hong et al. · Lipids | Nov 2004 | 347 |
| 42 | Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells Mark Bouwens, Ondine van de Rest, Neele S. Dellschaft et al. · American Journal of Clinical Nutrition | 11 Jun 2009 | 340 |
| 43 | A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases Chunxu Luo, Lin Zou, Huijun Sun et al. · Frontiers in Pharmacology | 28 Feb 2020 | 335 |
| 44 | Carbon Dioxide Fixation in Sugarcane Leaves Hugo P. Kortschak, Constance Endicott Hartt, George Oswald Burr · PLANT PHYSIOLOGY | Mar 1965 | 329 |
| 45 | Trans fats—sources, health risks and alternative approach - A review Vandana Dhaka, Neelam Gulia, Kulveer Singh Ahlawat et al. · Journal of Food Science and Technology | 27 Jan 2011 | 308 |
| 46 | In vitro and in vivo α-amylase and α-glucosidase inhibiting activities of the protein extracts from two varieties of bitter gourd (Momordica charantia L.) Sundar Poovitha, Madasamy Parani · BMC Complementary and Alternative Medicine | Jul 2016 | 305 |
| 47 | Anti-inflammatory effects of a low arachidonic acid diet and fish oil in patients with rheumatoid arthritis O. Adam, Corinna Beringer, Thomas Kless et al. · Rheumatology International | 2003 | 304 |
| 48 | Ulcer Prevention in Long-term Users of Nonsteroidal Anti-inflammatory Drugs David Yates Graham, Naurang M. Agrawal, Donald R. Campbell et al. · Archives of Internal Medicine | 28 Jan 2002 | 303 |
| 49 | Deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells by promoting ROS production Ruifen Kang, Ruonan Li, Pengyuan Dai et al. · Environmental Pollution | 10 May 2019 | 299 |
| 50 | Possible regeneration of the islets of langerhans in streptozotocin-diabetic rats given gymnema sylvestre leaf extracts E. R. B. Shanmugasundaram, K.Leela Gopinath, K. Radha Shanmugasundaram et al. · Journal of Ethnopharmacology | Oct 1990 | 295 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.