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Most cited papers in Neonatal Health and Biochemistry

What are the most cited papers in Neonatal Health and Biochemistry?

The most cited paper in Neonatal Health and Biochemistry is "Bilirubin Is an Antioxidant of Possible Physiological Importance" (Roland Stocker, Yorihiro Yamamoto, Antony F. McDonagh et al., 1987), with 3,543 citations. Next come "Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death" (3,370) and "A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates" (3,129).

Showing 50 of 100 papers. Every paper with more than 714 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Bilirubin Is an Antioxidant of Possible Physiological Importance Roland Stocker, Yorihiro Yamamoto, Antony F. McDonagh et al. · Science 27 Feb 1987 3,543
2 Mortality In Sickle Cell Disease -- Life Expectancy and Risk Factors for Early Death Orah S. Platt, Donald J. Brambilla, Wendell F. Rosse et al. · New England Journal of Medicine Open access 9 Jun 1994 3,370
3 A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates Nicholas J. Miller, Catherine A Rice-Evans, Michael J. Davies et al. · Clinical Science Apr 1993 3,129
4 Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Veit Hornung, Franz Georg Bauernfeind, Annett Halle et al. · Nature Immunology Open access 6 Jul 2008 3,083
5 Comments on ‘KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease’ K. Andrássy · Kidney International Open access 30 Aug 2013 2,520
6 AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIA Gian Luigi Sottocasa, Bo Kuylenstierna, Lars Ernster et al. · The Journal of Cell Biology Open access Feb 1967 2,322
7 Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications Stefan W. Ryter, Jawed Alam, Augustine M.K. Choi · Physiological Reviews Review Apr 2006 2,315
8 A SIMPLE PHENYLALANINE METHOD FOR DETECTING PHENYLKETONURIA IN LARGE POPULATIONS OF NEWBORN INFANTS Robert W. Guthrie, Ada Susi · PEDIATRICS Sep 1963 2,243
9 Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway Leo Edmond Otterbein, Fritz H. Bach, Jawed Alam et al. · Nature Medicine Apr 2000 2,159
10 Adenosine 3‘,5‘-Phosphate in Biological Materials Reginald W. Butcher, Earl W. Sutherland · Journal of Biological Chemistry Open access Apr 1962 2,090
11 Physiological concentrations of purines and pyrimidines Thomas W. Traut · Molecular and Cellular Biochemistry 1994 1,917
12 NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Jürg Tschopp, Kate Schroder · Nature reviews. Immunology Review 19 Feb 2010 1,855
13 Review and meta‐analysis of the epidemiology of congenital cytomegalovirus (CMV) infection Aileen Kenneson, Michael J. Cannon · Reviews in Medical Virology 20 Jun 2007 1,751
14 Identification of the haemoglobin scavenger receptor Mette Kristiansen, Jonas Heilskov Graversen, Christian Borch Jacobsen et al. · Nature 2001 1,728
15 Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications Mahin D. Maines · The FASEB Journal Jul 1988 1,718
16 The therapeutic potential of carbon monoxide Roberto Motterlini, Leo Edmond Otterbein · Nature Reviews Drug Discovery Review Sep 2010 1,643
17 The return of metabolism: biochemistry and physiology of the pentose phosphate pathway Anna Stincone, Alessandro Prigione, Thorsten Cramer et al. · Biological reviews/Biological reviews of the Cambridge Philosophical Society ReviewOpen access 22 Sep 2014 1,621
18 Glucose-6-phosphate dehydrogenase deficiency Maria Domenica Cappellini, Gabriel Amin Fiorelli · The Lancet 2008 1,594
19 Carbon Monoxide: a Putative Neural Messenger Ajay Mark Verma, David Jay Hirsch, Charles E. Glatt et al. · Science 15 Jan 1993 1,567
20 Pain in Sickle Cell Disease Orah S. Platt, Bruce D. Thorington, Donald J. Brambilla et al. · New England Journal of Medicine Open access 4 Jul 1991 1,559
21 The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin Russell P. Rother, Leonard B. Bell, Peter Hillmen et al. · JAMA 6 Apr 2005 1,555
22 Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease Robert H. Tukey, Christian Peer Strassburg · The Annual Review of Pharmacology and Toxicology Review Apr 2000 1,528
23 The interaction of a naphthalene dye with apomyoglobin and apohemoglobin Lubert Stryer · Journal of Molecular Biology Sep 1965 1,504
24 Efficacy of Intravitreal Bevacizumab for Stage 3+ Retinopathy of Prematurity Helen A. Mintz-Hittner, Kathleen A. Kennedy, Alice Z. Chuang · New England Journal of Medicine Open access 16 Feb 2011 1,470
25 The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome Piter J. Bosma, Jayanta Roy Chowdhury, Conny Bakker et al. · New England Journal of Medicine 2 Nov 1995 1,462
26 The Fetal Alcohol Syndrome Sterling K. Clarren, David W. Smith · New England Journal of Medicine 11 May 1978 1,362
27 Microsomal Heme Oxygenase R Tenhunen, Harvey S. Marver, Rudi Schmid · Journal of Biological Chemistry Open access Dec 1969 1,362
28 Structure of Hæmoglobin: A Three-Dimensional Fourier Synthesis at 5.5-Å. Resolution, Obtained by X-Ray Analysis Max Ferdinand Perutz, Michael George Rossmann, Ann F. Cullis et al. · Nature Feb 1960 1,357
29 Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion Lydia Aguilar‐Bryan, Colin G. Nichols, Sérgio Wechsler et al. · Science 21 Apr 1995 1,331
30 Reduced stress defense in heme oxygenase 1-deficient cells Kenneth D. Poss, Susumu Tonegawa · Proceedings of the National Academy of Sciences Open access 30 Sep 1997 1,313
31 Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides George Dubyak, Chakib El-Moatassim · American Journal of Physiology-Cell Physiology Sep 1993 1,249
32 Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates Frédéric B. Piel, Anand P. Patil, Rosalind E. Howes et al. · The Lancet Open access 24 Oct 2012 1,200
33 Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade Gennady G. Yegutkin · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Open access 13 Feb 2008 1,170
34 Heme oxygenase-1: unleashing the protective properties of heme Leo Edmond Otterbein, Miguel Parreira Soares, Kenichiro Yamashita et al. · Trends in Immunology Review 16 Jul 2003 1,167
35 Inherited haemoglobin disorders: an increasing global health problem. David John Weatherall, J. B. Clegg · PubMed Open access 2001 1,165
36 Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Caterina Borgna‐Pignatti, Simone Rugolotto, Piero De Stefano et al. · PubMed Oct 2004 1,127
37 Pharmacological and Clinical Aspects of Heme Oxygenase Nader G. Abraham, Attallah Kappas · Pharmacological Reviews Mar 2008 1,115
38 Iron-Chelating Therapy and the Treatment of Thalassemia Nancy F. Olivieri, Gary M. Brittenham · Blood Feb 1997 1,109
39 Biliverdin reductase: A major physiologic cytoprotectant David E. Barañano, Mahil Rao, Christopher D. Ferris et al. · Proceedings of the National Academy of Sciences Open access 27 Nov 2002 1,101
40 Red cell membrane: past, present, and future Narla Mohandas, Patrick G. Gallagher · Blood Open access 6 Nov 2008 1,089
41 Tumour lysis syndrome: new therapeutic strategies and classification Mitchell Stuart Cairo, Michael Russell Bishop · British Journal of Haematology 22 Jul 2004 1,078
42 Iodine Deficiency Michael Bruce Zimmermann · Endocrine Reviews Open access Jun 2009 1,075
43 Carbon Monoxide Poisoning Armin Ernst, Joseph D. Zibrak · New England Journal of Medicine 26 Nov 1998 1,075
44 Gases as biological messengers: nitric oxide and carbon monoxide in the brain T. Renee Dawson, SH Snyder · Journal of Neuroscience Open access Sep 1994 1,050
45 Iodine-deficiency disorders Michael Bruce Zimmermann, Pieter L. Jooste, Chandrakant S Pandav · The Lancet Open access 4 Aug 2008 1,047
46 Treatment of the Crigler–Najjar Syndrome Type I with Hepatocyte Transplantation Ira J. Fox, Jayanta Roy Chowdhury, Stuart S. Kaufman et al. · New England Journal of Medicine Open access 14 May 1998 1,041
47 A vertebrate globin expressed in the brain Thorsten Burmester, Bettina Weich, Sigrid Reinhardt et al. · Nature Sep 2000 1,028
48 Heme oxygenase 1 is required for mammalian iron reutilization Kenneth D. Poss, Susumu Tonegawa · Proceedings of the National Academy of Sciences Open access 30 Sep 1997 1,025
49 Estimation of Small Percentages of Fœtal Hæmoglobin Klaus Betke, Hanna Marti, Irmgard Schlicht · Nature Dec 1959 1,017
50 The Tumor Lysis Syndrome Scott C. Howard, Deborah P. Jones, Ching‐Hon Pui · New England Journal of Medicine Open access 11 May 2011 1,012

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.