Most cited papers in Nosocomial Infections in ICU

Nosocomial Infections in ICU

What are the most cited papers in Nosocomial Infections in ICU?

The most cited paper in Nosocomial Infections in ICU is "Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care" (Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey R. Lidicker et al., 2001), with 8,644 citations. Next come "Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012" (7,373) and "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016" (6,868).

Published TypeAccessAuthorsCitations

Showing 50 of 98 papers. Every paper with more than 1,209 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey R. Lidicker et al. · Critical Care Medicine	Jul 2001	8,644
2	Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012 Richard P. Dellinger et al. · Intensive Care Medicine Open access	29 Jan 2013	7,373
3	Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes et al. · Intensive Care Medicine Open access	18 Jan 2017	6,868
4	CDC/NHSN surveillance definition of health care–associated infection and criteria for specific types of infections in the acute care setting Teresa C Horan, Mary L. Andrus, Margaret A. Dudeck · American Journal of Infection Control	Jun 2008	6,712
5	Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries Giacomo Bellani, John Gerard Laffey, Tài Pham et al. · JAMA Open access	22 Feb 2016	6,014
6	The Epidemiology of Sepsis in the United States from 1979 through 2000 Greg S. Martin, David M. Mannino, Stephanie Eaton et al. · New England Journal of Medicine Open access	16 Apr 2003	5,909
7	Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 Laura Evans et al. · Intensive Care Medicine Open access	2 Oct 2021	5,314
8	A Prediction Rule to Identify Low-Risk Patients with Community-Acquired Pneumonia Michael J. Fine, Thomas E. Auble, Donald M. Yealy et al. · New England Journal of Medicine Open access	23 Jan 1997	4,685
9	Nosocomial Bloodstream Infections in US Hospitals: Analysis of 24,179 Cases from a Prospective Nationwide Surveillance Study Hilmar Wisplinghoff, Thomas Bischoff, Sandra M. Tallent et al. · Clinical Infectious Diseases Open access	22 Jul 2004	4,559
10	An Intervention to Decrease Catheter-Related Bloodstream Infections in the ICU Peter J. Pronovost, Dale M. Needham, Sean M. Berenholtz et al. · New England Journal of Medicine	27 Dec 2006	4,420
11	Multistate Point-Prevalence Survey of Health Care–Associated Infections Shelley S. Magill, Jonathan R. Edwards, Wendy Bamberg et al. · New England Journal of Medicine Open access	26 Mar 2014	4,028
12	Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society André C. Kalil, Mark L. Metersky, Michael Klompas et al. · Clinical Infectious Diseases Open access	14 Jul 2016	4,027
13	Assessment of Clinical Criteria for Sepsis Christopher W. Seymour, Vincent X. Liu, Theodore John Iwashyna et al. · JAMA Open access	22 Feb 2016	3,936
14	CDC definitions for nosocomial infections B. Yangco · American Journal of Infection Control	Feb 1989	3,787
15	Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007 Alicia Hidrón, Jonathan R. Edwards, Jean Baldus Patel et al. · Infection Control and Hospital Epidemiology Open access	23 Oct 2008	3,768
16	Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome Marcelo B. P. Amato, Carmen Sílvia Valente Barbas, Denise Machado Medeiros et al. · New England Journal of Medicine Open access	5 Feb 1998	3,691
17	International Study of the Prevalence and Outcomes of Infection in Intensive Care Units Jean‐Louis Vincent · JAMA Open access	Dec 2009	3,682
18	Assessment of Global Incidence and Mortality of Hospital-treated Sepsis: Current Estimates and Limitations Carolin Fleischmann-Struzek, André Scherag, Neill K. J. Adhikari et al. · American Journal of Respiratory and Critical Care Medicine	28 Sep 2015	3,667
19	Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America Leonard A. Mermel, Michael Allon, Emilio Bouza et al. · Clinical Infectious Diseases Open access	2 Jun 2009	3,661
20	Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial Giles J. Peek, Miranda Mugford, Ravindranath Tiruvoipati et al. · The Lancet	16 Sep 2009	3,434
21	Delirium in Mechanically Ventilated Patients Eugene Wesley Ely, Sharon K. Inouye, Gordon R. Bernard et al. · JAMA Open access	5 Dec 2001	3,249
22	Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study Wei Shen Lim · Thorax Open access	May 2003	3,175
23	Delirium as a Predictor of Mortality in Mechanically Ventilated Patients in the Intensive Care Unit E. Wesley Ely · JAMA Open access	14 Apr 2004	3,100
24	Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Tamar F. Barlam et al. · Clinical Infectious Diseases Open access	13 Apr 2016	3,087
25	Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation John Paul Kress, Anne S. Pohlman, Michael F. O’Connor et al. · New England Journal of Medicine Open access	18 May 2000	2,996
26	Estimating Health Care-Associated Infections and Deaths in U.S. Hospitals, 2002 R. Monina Klevens, Jonathan R. Edwards, Chesley L. Richards et al. · Public Health Reports Open access	Mar 2007	2,977
27	Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) Stuart H. Cohen, Dale N. Gerding, Stuart Johnson et al. · Infection Control and Hospital Epidemiology	22 Mar 2010	2,955
28	National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2003, issued August 2003 A report from the NNIS System · American Journal of Infection Control	Dec 2003	2,924
29	2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference for the International Sepsis Definitions Conference, Mitchell M. Levy, Mitchell P. Fink et al. · Intensive Care Medicine	28 Mar 2003	2,908
30	Sepsis in European intensive care units: Results of the SOAP study* Jean‐Louis Vincent, Yasser L. Sakr, Charles L. Sprung et al. · Critical Care Medicine	17 Jan 2006	2,893
31	Ventilator-associated Pneumonia Jean E. Chastre, Jean-Yves Fagon · American Journal of Respiratory and Critical Care Medicine	Apr 2002	2,838
32	Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) L. Clifford McDonald, Dale N. Gerding, Stuart Johnson et al. · Clinical Infectious Diseases Open access	14 Dec 2017	2,699
33	Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis Benedetta Allegranzi, Sepideh Bagheri Nejad, Christophe Combescure et al. · The Lancet ReviewOpen access	10 Dec 2010	2,590
34	How long do nosocomial pathogens persist on inanimate surfaces? A systematic review Axel Krämer, Ingeborg Schwebke, Günter Kampf · BMC Infectious Diseases ReviewOpen access	16 Aug 2006	2,546
35	Effectiveness of a hospital-wide programme to improve compliance with hand hygiene Didier Pittet, Stéphane Hugonnet, Stephan Harbarth et al. · The Lancet	Oct 2000	2,541
36	Evaluation of delirium in critically ill patients: Validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) Eugene Wesley Ely, Richard A. Margolin, Joseph Francis et al. · Critical Care Medicine	Jul 2001	2,493
37	High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure J. P. Frat et al. · New England Journal of Medicine Open access	17 May 2015	2,419
38	National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004 A report from the NNIS System · American Journal of Infection Control Open access	Dec 2004	2,355
39	Time to Treatment and Mortality during Mandated Emergency Care for Sepsis Christopher W. Seymour, Foster C. Gesten, Hallie C. Prescott et al. · New England Journal of Medicine Open access	21 May 2017	2,302
40	Sepsis and septic shock Maurizio Cecconi, Laura Evans, Mitchell M. Levy et al. · The Lancet	21 Jun 2018	2,297
41	Klebsiella pneumoniae: Going on the Offense with a Strong Defense Michelle K. Paczosa, Joan C. Mecsas · Microbiology and Molecular Biology Reviews ReviewOpen access	16 Jun 2016	2,062
42	Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease Laurent Brochard, Jordi Mancebo, Marc Wysocki et al. · New England Journal of Medicine Open access	28 Sep 1995	2,060
43	A Predominantly Clonal Multi-Institutional Outbreak ofClostridium difficile–Associated Diarrhea with High Morbidity and Mortality Vivian G. Loo, Louise Poirier, Mark A. Miller et al. · New England Journal of Medicine	2 Dec 2005	1,955
44	Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014 Chanu Rhee, Raymund Dantes, Lauren H. Epstein et al. · JAMA Open access	13 Sep 2017	1,941
45	Treatment of stage I–III periodontitis—The EFP S3 level clinical practice guideline Mariano Sanz, David Herrera, Moritz Kebschull et al. · Journal Of Clinical Periodontology Open access	8 May 2020	1,879
46	Health Care–Associated Infections Eyal Zimlichman, Daniel Henderson, Orly Tamir et al. · JAMA Internal Medicine	2 Sep 2013	1,879
47	Characteristics and Outcomes in Adult Patients Receiving Mechanical Ventilation A 28-Day International Study Andrés Esteban · JAMA	16 Jan 2002	1,828
48	Inadequate Antimicrobial Treatment of Infections Marin H. Kollef, Glenda Sherman, Suzanne M. Ward et al. · CHEST Journal	Feb 1999	1,824
49	The Influence of Inadequate Antimicrobial Treatment of Bloodstream Infections on Patient Outcomes in the ICU Setting Emad H. Ibrahim, Glenda Sherman, Suzanne M. Ward et al. · CHEST Journal	Jul 2000	1,806
50	Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012 Kirsi‐Maija Kaukonen, Michael Bailey, Satoshi Suzuki et al. · JAMA	18 Mar 2014	1,741

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.