Topic · Nuclear Structure and Function
Most cited papers in Nuclear Structure and Function
What are the most cited papers in Nuclear Structure and Function?
The most cited paper in Nuclear Structure and Function is "Liquid phase condensation in cell physiology and disease" (Yongdae Shin, Clifford P. Brangwynne, 2017), with 4,580 citations. Next come "Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17" (3,560) and "Liquid-Liquid Phase Separation in Biology" (3,414).
Showing 50 of 98 papers. Every paper with more than 856 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Liquid phase condensation in cell physiology and disease Yongdae Shin, Clifford P. Brangwynne · Science | 21 Sep 2017 | 4,580 |
| 2 | Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 Mike Hutton et al. · Nature | Jun 1998 | 3,560 |
| 3 | Liquid-Liquid Phase Separation in Biology Anthony A. Hyman, Christoph Andreas Weber, Frank Jülicher · Annual Review of Cell and Developmental Biology | 6 Oct 2014 | 3,414 |
| 4 | Shelterin: the protein complex that shapes and safeguards human telomeres Titia de Lange · Genes & Development | 15 Sep 2005 | 3,078 |
| 5 | Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs Rui Yi, Yi Qin, Ian G. Macara et al. · Genes & Development | 2003 | 3,016 |
| 6 | Phase transitions in the assembly of multivalent signalling proteins Pilong Li, Sudeep Banjade, Hui-Chun Cheng et al. · Nature | Mar 2012 | 2,797 |
| 7 | Nuclear Export of MicroRNA Precursors Elsebet Lund, Stephan Güttinger, Ângelo Calado et al. · Science | 24 Nov 2003 | 2,721 |
| 8 | A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells Kyle J. Roux, Dae In Kim, Manfred Raida et al. · The Journal of Cell Biology | 12 Mar 2012 | 2,636 |
| 9 | A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors Andrew Carr, Katherine Samaras, Samantha Burton et al. · AIDS | May 1998 | 2,409 |
| 10 | Dynamic regulation of genome-wide pre-mRNA splicing and stress tolerance by the Sm-like protein LSm5 in Arabidopsis Peng Cui, Shoudong Zhang, Feng Hua Ding et al. · Genome biology | 6 Jan 2014 | 2,339 |
| 11 | Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation Richard Maury Stone et al. · New England Journal of Medicine | 23 Jun 2017 | 2,258 |
| 12 | Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome Maria J Eriksson, William Ted Brown, Leslie B. Gordon et al. · Nature | 25 Apr 2003 | 2,252 |
| 13 | Data on the distribution of fibre types in thirty-six human muscles Mark A. Johnson, József Péter Polgár, Andrew Weightman et al. · Journal of the Neurological Sciences | 1973 | 2,214 |
| 14 | A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage Tanya T. Paull, Emmy P. Rogakou, Vikky Yamazaki et al. · Current Biology | Aug 2000 | 2,107 |
| 15 | CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals Maarten W.J. Fornerod, Mutsuhito Ohno, Minoru Yoshida et al. · Cell | Sep 1997 | 2,106 |
| 16 | Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation Joe Swift, Irena Lambrova Ivanovska, Amnon Buxboim et al. · Science | 29 Aug 2013 | 2,080 |
| 17 | Transport Between the Cell Nucleus and the Cytoplasm Dirk Görlich, Ulrike Kutay · Annual Review of Cell and Developmental Biology | Nov 1999 | 2,054 |
| 18 | Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements Wes Lee, Pamela J. Mitchell, Robert Tjian · Cell | Jun 1987 | 2,047 |
| 19 | Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions Lars Guelen, Ludo Pagie, Émilie Brasset et al. · Nature | 7 May 2008 | 2,045 |
| 20 | Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes Alexander L. Klibanov, Kazuo Maruyama, Vladimir P. Torchilin et al. · FEBS Letters | 30 Jul 1990 | 2,026 |
| 21 | Cytoplasmic Nucleophosmin in Acute Myelogenous Leukemia with a Normal Karyotype Brunangelo Falini et al. · New England Journal of Medicine | 19 Jan 2005 | 1,923 |
| 22 | How Shelterin Protects Mammalian Telomeres Wilhelm Palm, Titia de Lange · Annual Review of Genetics | 4 Aug 2008 | 1,815 |
| 23 | Polymer physics of intracellular phase transitions Clifford P. Brangwynne, Péter Tompa, Rohit V. Pappu · Nature Physics | Nov 2015 | 1,716 |
| 24 | Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Z D Cao, Robert M. Umek, Steven Lanier McKnight · Genes & Development | Sep 1991 | 1,694 |
| 25 | The muscular dystrophies Alan E H Emery · The Lancet | Feb 2002 | 1,674 |
| 26 | Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: acohort study Andrew D Carr, Katherine Samaras, Anna Sesselja Þórisdóttir et al. · The Lancet | Jun 1999 | 1,520 |
| 27 | Truncations of Titin Causing Dilated Cardiomyopathy Daniel S. Herman et al. · New England Journal of Medicine | 15 Feb 2012 | 1,514 |
| 28 | Phosphorylation of c-jun mediated by MAP kinases Bernd Pulverer, John M. Kyriakis, Joseph Avruch et al. · Nature | Oct 1991 | 1,493 |
| 29 | Lamin A Truncation in Hutchinson-Gilford Progeria Annachiara De Sandre‐Giovannoli, Rafaëlle Bernard, Pierre Cau et al. · Science | 21 Apr 2003 | 1,488 |
| 30 | Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs Markus T. Bohnsack, Kevin Czaplinski, Dirk Görlich · RNA | 16 Jan 2004 | 1,428 |
| 31 | The Yeast Nuclear Pore Complex Michael P. Rout, John D. Aitchison, Adisetyantari Suprapto et al. · The Journal of Cell Biology | 21 Feb 2000 | 1,417 |
| 32 | Nuclear envelope rupture and repair during cancer cell migration Céline Denais, Rachel M. Gilbert, Philipp Isermann et al. · Science | 25 Mar 2016 | 1,410 |
| 33 | The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics Shana Elbaum‐Garfinkle, Younghoon Kim, Krzysztof Szczepaniak et al. · Proceedings of the National Academy of Sciences | 26 May 2015 | 1,408 |
| 34 | Coupling of the nucleus and cytoplasm: Role of the LINC complex Melissa Crisp, Qian Liu, Kyle J. Roux et al. · The Journal of Cell Biology | 27 Dec 2005 | 1,394 |
| 35 | Missense Mutations in the Rod Domain of the Lamin A/C Gene as Causes of Dilated Cardiomyopathy and Conduction-System Disease Diane Fatkin, Calum A. MacRae, Takeshi Sasaki et al. · New England Journal of Medicine | 2 Dec 1999 | 1,371 |
| 36 | Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy Gisèle Bonne, Marina Raffaele di Barletta, Shaïda Varnous et al. · Nature Genetics | Mar 1999 | 1,362 |
| 37 | Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs Shunichi Kosugi, Masako Hasebe, Masaru Tomita et al. · Proceedings of the National Academy of Sciences | 11 Jun 2009 | 1,346 |
| 38 | Hypertrophic Cardiomyopathy Pascale Richard, Philippe Charron, Lucie Carrier et al. · Circulation | 5 May 2003 | 1,287 |
| 39 | Acute Phase Proteins with Special Reference to C-Reactive Protein and Related Proteins (Pentaxins) and Serum Amyloid A Protein Mark B. Pepys, M L Baltz · Advances in immunology | 1983 | 1,285 |
| 40 | Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression Bas van Steensel, Andrew S. Belmont · Cell | May 2017 | 1,258 |
| 41 | Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing Simon Alberti, Anthony A. Hyman · Nature Reviews Molecular Cell Biology | 28 Jan 2021 | 1,256 |
| 42 | A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2 Rohit K. Mahajan, Christian Delphin, Tinglu Guan et al. · Cell | 1997 | 1,255 |
| 43 | Lamin A-Dependent Nuclear Defects in Human Aging Paola Scaffidi, Tom Misteli · Science | 27 Apr 2006 | 1,254 |
| 44 | Leptin-Replacement Therapy for Lipodystrophy Elif Arioglu Oral, Vinaya Simha, Elaine Ruiz et al. · New England Journal of Medicine | 21 Feb 2002 | 1,243 |
| 45 | Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy Teresa L. Sullivan, Diana Escalante‐Alcalde, Harshida Bhatt et al. · The Journal of Cell Biology | 29 Nov 1999 | 1,230 |
| 46 | CRM1 is responsible for intracellular transport mediated by the nuclear export signal Makoto Fukuda, Shiro Asano, Takahiro Nakamura et al. · Nature | Nov 1997 | 1,224 |
| 47 | High mobility of proteins in the mammalian cell nucleus Robert D. Phair, Tom Misteli · Nature | Apr 2000 | 1,222 |
| 48 | Identification of a signal for rapid export of proteins from the nucleus Wei Wen, Judy L Meinkotht, Roger Y. Tsien et al. · Cell | Aug 1995 | 1,206 |
| 49 | A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. Michael J. Matunis, Elias E. Coutavas, Gerd A. Blobel · The Journal of Cell Biology | 15 Dec 1996 | 1,199 |
| 50 | NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase Iain W. Mattaj, Ludwig Englmeier · Annual Review of Biochemistry | Jun 1998 | 1,182 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.