Most cited papers in Organic Chemistry Cycloaddition Reactions
What are the most cited papers in Organic Chemistry Cycloaddition Reactions?
The most cited paper in Organic Chemistry Cycloaddition Reactions is "Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes" (Hermann Esterbauer, Rudolf Jörg Schaur, Helmward Zöllner, 1991), with 6,700 citations. Next come "Using redundant internal coordinates to optimize equilibrium geometries and transition states" (2,751) and "A Molecular Orbital Theory of Reactivity in Aromatic Hydrocarbons" (2,333).
Showing 50 of 100 papers. Every paper with more than 401 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes Hermann Esterbauer, Rudolf Jörg Schaur, Helmward Zöllner · Free Radical Biology and Medicine | 1991 | 6,700 |
| 2 | Using redundant internal coordinates to optimize equilibrium geometries and transition states Chunyang Peng, Philippe Y. Ayala, H. Bernhard Schlegel et al. · Journal of Computational Chemistry | 15 Jan 1996 | 2,751 |
| 3 | A Molecular Orbital Theory of Reactivity in Aromatic Hydrocarbons Kenichi Fukui, Teijiro Yonezawa, Haruo Shingu · The Journal of Chemical Physics | Apr 1952 | 2,333 |
| 4 | Asymmetric 1,3-Dipolar Cycloaddition Reactions Kurt V. Gothelf, Karl Anker Jørgensen · Chemical Reviews | 14 Mar 1998 | 1,913 |
| 5 | Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization Yun Liang Gao, Janice M. Klunder, Robert Mark Hanson et al. · Journal of the American Chemical Society | Sep 1987 | 1,877 |
| 6 | Behavior of Ylides Containing N, O, and C Atoms as Hydrogen Bond Acceptors Isabel Rozas, Ibón Alkorta, José Elguero · Journal of the American Chemical Society | Nov 2000 | 1,739 |
| 7 | IMOMM: A new integrated ab initio + molecular mechanics geometry optimization scheme of equilibrium structures and transition states Feliu Maseras, Keiji Morokuma · Journal of Computational Chemistry | Sep 1995 | 1,721 |
| 8 | New Dual Descriptor for Chemical Reactivity Christophe Morell, André Grand, Alejandro Toro‐Labbé · The Journal of Physical Chemistry A | 13 Dec 2004 | 1,375 |
| 9 | Neuroactive steroids Steven M. Paul, Robert H. Purdy · The FASEB Journal | Mar 1992 | 1,329 |
| 10 | Applications of the Conceptual Density Functional Theory Indices to Organic Chemistry Reactivity Luis Ramon Domingo, Mar Ríos‐Gutiérrez, Patricia Pérez · Molecules | 9 Jun 2016 | 1,327 |
| 11 | Biomedical Importance of Indoles Nagendra Kumar Kaushik, Neha Kaushik, Pankaj Attri et al. · Molecules | 6 Jun 2013 | 1,245 |
| 12 | Quantitative characterization of the global electrophilicity power of common diene/dienophile pairs in Diels–Alder reactions Luis Ramon Domingo, María José Aurell, Patricia Pérez et al. · Tetrahedron | May 2002 | 1,085 |
| 13 | Understanding the Reactivity of Captodative Ethylenes in Polar Cycloaddition Reactions. A Theoretical Study Luis Ramon Domingo, Eduardo E. Chamorro, Patricia Pérez · The Journal of Organic Chemistry | 17 May 2008 | 1,073 |
| 14 | Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms Hui Fan, Jiangnan Peng, Mark T. Hamann et al. · Chemical Reviews | 21 Dec 2007 | 1,063 |
| 15 | Intramolecular Dipolar Cycloaddition Reactions of Azomethine Ylides Iain Coldham, Richard Hufton · Chemical Reviews | 25 Jun 2005 | 1,017 |
| 16 | π-Nucleophilicity in Carbon−Carbon Bond-Forming Reactions Herbert Mayr, Bernhard Kempf, Armin R. Ofial · Accounts of Chemical Research | 30 Aug 2002 | 1,014 |
| 17 | Distortion/Interaction Energy Control of 1,3-Dipolar Cycloaddition Reactivity Daniel H. Ess, Kendall N. Houk · Journal of the American Chemical Society | 9 Aug 2007 | 1,012 |
| 18 | Halogen Bonding: A Paradigm in Supramolecular Chemistry Pierangelo Metrangolo, Giuseppe Resnati · Chemistry - A European Journal | 18 Jun 2001 | 999 |
| 19 | Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution Jeremy R. Greenwood, David R. Calkins, Arron P. Sullivan et al. · Journal of Computer-Aided Molecular Design | 30 Mar 2010 | 993 |
| 20 | Catalytic Enantioselective Diels-Alder Reactions: Methods, Mechanistic Fundamentals, Pathways, and Applications Elias James Corey · Angewandte Chemie International Edition | 17 May 2002 | 982 |
| 21 | Mechanistic Aspects of Diels‐Alder Reactions: A Critical Survey Jürgen Sauer, Reiner Sustmann · Angewandte Chemie International Edition in English | Oct 1980 | 952 |
| 22 | Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction Justin B. Siegel, Alexandre Zanghellini, Helena M. Lovick et al. · Science | 15 Jul 2010 | 944 |
| 23 | Highly potent and selective ligands for histamine H3-receptors J.M. Arrang, Monique Garbarg, J.-C. Lancelo et al. · Nature | May 1987 | 907 |
| 24 | Understanding the local reactivity in polar organic reactions through electrophilic and nucleophilic Parr functions Luis Ramon Domingo, Patricia Pérez, Jose Antonio De Saja Saez · RSC Advances | 14 Nov 2012 | 853 |
| 25 | Theory of 1,3-Dipolar Cycloadditions: Distortion/Interaction and Frontier Molecular Orbital Models Daniel H. Ess, Kendall N. Houk · Journal of the American Chemical Society | 10 Jul 2008 | 853 |
| 26 | Hexafluoroisopropanol as a highly versatile solvent Ignacio Colomer, Anna E. R. Chamberlain, Maxwell B. Haughey et al. · Nature Reviews Chemistry | 8 Nov 2017 | 830 |
| 27 | Philicity: A Unified Treatment of Chemical Reactivity and Selectivity Pratim Kumar Chattaraj, Buddhadev Maiti, Utpal Sarkar · The Journal of Physical Chemistry A | 30 May 2003 | 827 |
| 28 | Synthetically Useful Reactions of Epoxides Janice Gorzynski Smith · Synthesis | 1984 | 795 |
| 29 | A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design Brett R. Beno, Kap‐Sun Yeung, Michael D. Bartberger et al. · Journal of Medicinal Chemistry | 3 Mar 2015 | 785 |
| 30 | Improved algorithms for reaction path following: Higher-order implicit algorithms Carlos Alberto Gonzalez, H. Bernhard Schlegel · The Journal of Chemical Physics | 15 Oct 1991 | 778 |
| 31 | Approaches for Optimizing the First Electronic Hyperpolarizability of Conjugated Organic Molecules Seth R. Marder, David N. Beratan, Lu Cheng · Science | 5 Apr 1991 | 752 |
| 32 | Scales of Nucleophilicity and Electrophilicity: A System for Ordering Polar Organic and Organometallic Reactions Herbert Mayr, Matthias Patz · Angewandte Chemie International Edition in English | 18 May 1994 | 744 |
| 33 | Transition metal complexes of o-benzoquinone, o-semiquinone, and catecholate ligands Cortlandt G. Pierpont, Robert M. Buchanan · Coordination Chemistry Reviews | Aug 1981 | 742 |
| 34 | On finding transition states C. Cerjan, William Hughes Miller · The Journal of Chemical Physics | 15 Sep 1981 | 738 |
| 35 | Molecular Orbital Theory of Orientation in Aromatic, Heteroaromatic, and Other Conjugated Molecules Kenichi Fukui, Teijiro Yonezawa, Chikayoshi Nagata et al. · The Journal of Chemical Physics | Aug 1954 | 734 |
| 36 | Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics Varun Bhardwaj, Divya Gumber, Vikrant Abbot et al. · RSC Advances | 2015 | 696 |
| 37 | Tandem [4+2]/[3+2] Cycloadditions of Nitroalkenes Scott E. Denmark, Atli Thorarensen · Chemical Reviews | 1996 | 691 |
| 38 | [2+2+2] Cycloaddition Reactions Catalyzed by Transition Metal Complexes Pramod R. Chopade, Janis Louie · Advanced Synthesis & Catalysis | Nov 2006 | 690 |
| 39 | Asymmetric organocatalysis Hélène Pellissier · Tetrahedron | 6 Jul 2007 | 682 |
| 40 | Photoremovable protecting groups: reaction mechanisms and applications Anna Paola Pelliccioli, Jakob Wirz · Photochemical & Photobiological Sciences | 6 Jun 2002 | 671 |
| 41 | Thienothiophenes, Dithienothiophenes, and Thienoacenes: Syntheses, Oligomers, Polymers, and Properties Mehmet Emin Cinar, Turan Öztürk · Chemical Reviews | Apr 2015 | 667 |
| 42 | Recent Advances in the Friedländer Reaction Jose Luis Marco-Contelles, Elena Pérez‐Mayoral, Abdelouahid Samadi et al. · Chemical Reviews | 10 Apr 2009 | 663 |
| 43 | Difluoromethyl Bioisostere: Examining the “Lipophilic Hydrogen Bond Donor” Concept Yossi Zafrani, Dina Yeffet, Gali Sod‐Moriah et al. · Journal of Medicinal Chemistry | 4 Jan 2017 | 656 |
| 44 | Catalytic asymmetric epoxidation of unfunctionalized olefins Ryo Irie, Keiko Noda, Yoshio Ito et al. · Tetrahedron Letters | 1990 | 654 |
| 45 | A new C–C bond formation model based on the quantum chemical topology of electron density Luis Ramon Domingo · RSC Advances | 2014 | 640 |
| 46 | Saturated bioisosteres of benzene: where to go next? Pavel K. Mykhailiuk · Organic & Biomolecular Chemistry | 2019 | 634 |
| 47 | The nucleophilicity N index in organic chemistry Luis Ramon Domingo, Patricia Pérez · Organic & Biomolecular Chemistry | 2011 | 629 |
| 48 | An Efficient Catalytic Asymmetric Epoxidation Method Zhixian Wang, Yong Qiang Tu, Michael J. Frohn et al. · Journal of the American Chemical Society | Nov 1997 | 627 |
| 49 | Heterocycles in Medicinal Chemistry Josef Jampílek · Molecules | 25 Oct 2019 | 620 |
| 50 | Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions Fabio Bellina, Renzo Rossi · Tetrahedron | 16 Jun 2006 | 606 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.