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Most cited papers in Pain Management and Treatment

What are the most cited papers in Pain Management and Treatment?

The most cited paper in Pain Management and Treatment is "Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity" (Alban Latrémolière, Clifford J. Woolf, 2009), with 3,917 citations. Next come "Human brain mechanisms of pain perception and regulation in health and disease" (3,160) and "Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee" (2,859).

Showing 50 of 100 papers. Every paper with more than 622 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity Alban Latrémolière, Clifford J. Woolf · Journal of Pain Open access 26 Aug 2009 3,917
2 Human brain mechanisms of pain perception and regulation in health and disease A. Vania Apkarian, M. Catherine Bushnell, Rolf‐Detlef Treede et al. · European Journal of Pain Open access 25 Jan 2005 3,160
3 Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee Paolo Maria Rossini et al. · Clinical Neurophysiology Open access 10 Feb 2015 2,859
4 Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014–2018) Jean‐Pascal Lefaucheur et al. · Clinical Neurophysiology Open access 31 Dec 2019 2,413
5 pain DETECT : a new screening questionnaire to identify neuropathic components in patients with back pain Rainer Freynhagen, Ralf Baron, Ulrich Gockel et al. · Current Medical Research and Opinion Open access 29 Aug 2006 2,304
6 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria Frederick Wolfe, Daniel Joseph Clauw, Mary‐Ann Fitzcharles et al. · Seminars in Arthritis and Rheumatism 6 Sep 2016 2,223
7 The Stabilizing System of the Spine. Part I. Function, Dysfunction, Adaptation, and Enhancement Manohar M. Panjabi · Journal of Spinal Disorders Dec 1992 2,187
8 Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial John P. O’Reardon, H. Brent Solvason, Philip G. Janicak et al. · Biological Psychiatry 31 Jul 2007 1,941
9 Transcranial Magnetic Stimulation: A Primer Mark Hallett · Neuron Open access Jul 2007 1,940
10 Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS) Jean‐Pascal Lefaucheur et al. · Clinical Neurophysiology Open access 28 Oct 2016 1,878
11 'Vascular Depression' Hypothesis George S. Alexopoulos · Archives of General Psychiatry Oct 1997 1,858
12 Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation Herta Flor, Thomas R. Elbert, Stefan Knecht et al. · Nature Open access Jun 1995 1,849
13 Optimal Medical Therapy With or Without Percutaneous Coronary Intervention to Reduce Ischemic Burden Leslee J. Shaw et al. · Circulation 11 Feb 2008 1,609
14 Pathways to Diabetic Limb Amputation: Basis for Prevention Roger E. Pecoraro, Gayle E. Reiber, Ernest M. Burgess · Diabetes Care May 1990 1,591
15 Comparison of the Short-Term Survival Benefit Associated With Revascularization Compared With Medical Therapy in Patients With No Prior Coronary Artery Disease Undergoing Stress Myocardial Perfusion Single Photon Emission Computed Tomography Rory Hachamovitch, Sean W. Hayes, John D. Friedman et al. · Circulation 4 Jun 2003 1,574
16 Responsiveness of the Numeric Pain Rating Scale in Patients with Low Back Pain John D. Childs, Sara Regina Piva, Julie M. Fritz · Spine 26 May 2005 1,487
17 Clinical research with transcranial direct current stimulation (tDCS): Challenges and future directions ANDRÉ RUSSOWSKY BRUNONI, Michael Andreas Nitsche, Nadia Bolognini et al. · Brain stimulation Open access Apr 2011 1,476
18 Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016 Marom Bikson et al. · Brain stimulation Open access 17 Jun 2016 1,438
19 The IASP classification of chronic pain for ICD-11: chronic primary pain Michael K. Nicholas, Johan W.S. Vlaeyen, Winfried Rief et al. · Pain Open access 22 Dec 2018 1,433
20 Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion. Karin Przyklenk, Barbara Bauer, Michel Ovize et al. · Circulation Open access Mar 1993 1,385
21 Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial Daniel M. Blumberger, Fidel Vila‐Rodriguez, Kevin E. Thorpe et al. · The Lancet Apr 2018 1,365
22 Validation of proposed diagnostic criteria (the “Budapest Criteria”) for Complex Regional Pain Syndrome Norman R. Harden, Stephen P. Bruehl, Roberto S.G.M. Perez et al. · Pain Open access 21 May 2010 1,325
23 Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression Alvaro Pascual-Leone, Belén Rubio, Federico Vicente Pallardó et al. · The Lancet Jul 1996 1,251
24 Spinal cord stimulation versus conventional medical management for neuropathic pain: A multicentre randomised controlled trial in patients with failed back surgery syndrome Krishna Kumar, Rod Stephen Taylor, Line G Jacques et al. · Pain 13 Sep 2007 1,192
25 Signs and symptoms of reflex sympathetic dystrophy: prospective study of 829 patients Peter H.J.M. Veldman, Han Reynen, I.E. Arntz et al. · The Lancet Oct 1993 1,151
26 Serious Complications Related to Regional Anesthesia Yves Auroy, P. Narchi, Antoine Messiah et al. · Anesthesiology Sep 1997 1,120
27 Reflex sympathetic dystrophy: changing concepts and taxonomy Michael D. Stanton-Hicks, Wilfrid Jänig, Samuel J. Hassenbusch et al. · Pain Oct 1995 1,104
28 Daily Left Prefrontal Transcranial Magnetic Stimulation Therapy for Major Depressive Disorder Mark S. George, Sarah Hollingsworth Lisanby, David Avery et al. · Archives of General Psychiatry May 2010 1,097
29 Morphine, Gabapentin, or Their Combination for Neuropathic Pain Ian Gilron, Joan M. Bailey, Dongsheng Tu et al. · New England Journal of Medicine Open access 30 Mar 2005 1,095
30 The perception of phantom limbs. The D. O. Hebb lecture V. Ramachandran · Brain Open access Sep 1998 1,058
31 The VIVA Trial Timothy D. Henry, Brian Herb Annex, George R. McKendall et al. · Circulation 18 Mar 2003 1,030
32 Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes Claudia S. Maier et al. · Pain 8 Jun 2010 1,029
33 Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial Rasha Kadem Al-Lamee et al. · The Lancet Open access 2 Nov 2017 1,026
34 Prophylactic Use of Implanted Cardiac Defibrillators in Patients at High Risk for Ventricular Arrhythmias after Coronary-Artery Bypass Graft Surgery J. Thomas Bigger · New England Journal of Medicine Open access 27 Nov 1997 1,020
35 Gene Therapy for Myocardial Angiogenesis Douglas W. Losordo, Peter R. Vale, James F. Symes et al. · Circulation Open access 22 Dec 1998 996
36 The incidence of complex regional pain syndrome: A population-based study Marissa de Mos, Anke G. J. de Bruijn, Frank J.P.M. Huygen et al. · Pain 8 Nov 2006 982
37 Temporary Abolition of Pain in Man Patrick David Wall, William H. Sweet · Science 6 Jan 1967 973
38 Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression Mark S. George, Eric M. Wassermann, Wendol A Williams et al. · Neuroreport Oct 1995 970
39 Fear-Avoidance Model of Chronic Pain Geert Crombez, Christopher Eccleston, Stefaan Van Damme et al. · Clinical Journal of Pain Open access 6 Jun 2012 966
40 Do we need a third mechanistic descriptor for chronic pain states? Eva Kosek, Milton L Cohen, Ralf Baron et al. · Pain 30 Jan 2016 961
41 Proposed New Diagnostic Criteria for Complex Regional Pain Syndrome Robert Norman Harden, Stephen P. Bruehl, Michael D. Stanton-Hicks et al. · Pain Medicine 12 Feb 2007 958
42 Multidisciplinary rehabilitation for chronic low back pain: systematic review Jaime Guzmán, Rosmin Esmail, Kaija Karjalainen et al. · BMJ ReviewOpen access 23 Jun 2001 944
43 Spinal Cord Stimulation versus Repeated Lumbosacral Spine Surgery for Chronic Pain: A Randomized, Controlled Trial Richard B. North, David H. Kidd, Farrokh Farrokhi et al. · Neurosurgery 2005 933
44 The vascular depression hypothesis: mechanisms linking vascular disease with depression Warren D. Taylor, Howard Jay Aizenstein, George S. Alexopoulos · Molecular Psychiatry Open access 26 Feb 2013 922
45 Temporary scaffolding of coronary arteries with bioabsorbable magnesium stents: a prospective, non-randomised multicentre trial Raimund Erbel, Carlo Di Mario, Jozef Bartúnek et al. · The Lancet Jun 2007 911
46 Phantom limb pain: a case of maladaptive CNS plasticity? Herta Flor, Lone Nikolajsen, Troels Staehelin Jensen · Nature reviews. Neuroscience Review 20 Oct 2006 911
47 Regional Cerebral Blood Flow Measured During Symptom Provocation in Obsessive-Compulsive Disorder Using Oxygen 15—Labeled Carbon Dioxide and Positron Emission Tomography Scott L. Rauch · Archives of General Psychiatry 1994 893
48 Spinal Cord Stimulation in Patients with Chronic Reflex Sympathetic Dystrophy Marius A. Kemler, Gerard A.M. Barendse, Maarten van Kleef et al. · New England Journal of Medicine Open access 31 Aug 2000 886
49 Complications after cardiac implantable electronic device implantations: an analysis of a complete, nationwide cohort in Denmark Rikke Esberg Kirkfeldt, Jens Brock Johansen, Ellen Aagaard Nohr et al. · European Heart Journal Open access 17 Dec 2013 877
50 International standardization of diagnostic criteria for microvascular angina Peter Ong, Paolo Guido Camici, John Francis Beltrame et al. · International Journal of Cardiology 8 Sep 2017 856

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.