Most cited papers in Phagocytosis and Immune Regulation
What are the most cited papers in Phagocytosis and Immune Regulation?
The most cited paper in Phagocytosis and Immune Regulation is "The biochemistry of apoptosis" (Michael Otmar Hengartner, 2000), with 7,357 citations. Next come "Cell Death: The Significance of Apoptosis" (7,243) and "Caspases: Enemies Within" (6,945).
Showing 50 of 99 papers. Every paper with more than 1,454 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The biochemistry of apoptosis Michael Otmar Hengartner · Nature | Oct 2000 | 7,357 |
| 2 | Cell Death: The Significance of Apoptosis A H Wyllie, John F. R. Kerr, Richard A. Currie · International review of cytology | 1980 | 7,243 |
| 3 | Caspases: Enemies Within Nancy A. Thornberry, Yuri A. Lazebnik · Science | 28 Aug 1998 | 6,945 |
| 4 | Apoptosis in the Pathogenesis and Treatment of Disease Craig B. Thompson · Science | 10 Mar 1995 | 6,597 |
| 5 | Macrophage plasticity and polarization: in vivo veritas Antonio Sica, Alberto Mantovani · Journal of Clinical Investigation | Mar 2012 | 6,482 |
| 6 | The Inflammasome Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell | Aug 2002 | 6,126 |
| 7 | Death Receptors: Signaling and Modulation Avi Ashkenazi, Vishva M. Dixit · Science | 28 Aug 1998 | 5,896 |
| 8 | A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V István Vermes, C. Haanen, Helga M. Steffens-nakken et al. · Journal of Immunological Methods | Jul 1995 | 5,471 |
| 9 | Protective and pathogenic functions of macrophage subsets Peter J. Murray, Thomas A. Wynn · Nature reviews. Immunology | 14 Oct 2011 | 5,326 |
| 10 | Macrophage plasticity, polarization, and function in health and disease Abbas Shapouri Moghaddam, Saeed Mohammadian Haftcheshmeh, Hossein Vazini et al. · Journal of Cellular Physiology | 10 Jan 2018 | 5,011 |
| 11 | Macrophage biology in development, homeostasis and disease Thomas A. Wynn, Ajay Chawla, Jeffrey W. Pollard · Nature | Apr 2013 | 4,816 |
| 12 | The M1 and M2 paradigm of macrophage activation: time for reassessment Fernando O. Martínez, Siamon Gordon · F1000Prime Reports | 28 Feb 2014 | 4,795 |
| 13 | Tumour-associated macrophages as treatment targets in oncology Alberto Mantovani, Federica Marchesi, Alberto Malesci et al. · Nature Reviews Clinical Oncology | 24 Jan 2017 | 4,183 |
| 14 | Tumor-Associated Macrophages: From Mechanisms to Therapy Roy Noy, Jeffrey W. Pollard · Immunity | Jul 2014 | 4,165 |
| 15 | Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm Subhra Kumar Biswas, Alberto Mantovani · Nature Immunology | 20 Sep 2010 | 3,880 |
| 16 | BCL-2 family members and the mitochondria in apoptosis Atan Gross, James M. McDonnell, S J Korsmeyer · Genes & Development | Aug 1999 | 3,664 |
| 17 | The Tumor Microenvironment Innately Modulates Cancer Progression Dominique C. Hinshaw, Lalita A. Shevde · Cancer Research | 26 Jul 2019 | 3,497 |
| 18 | Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 Guido Kroemer et al. · Cell Death and Differentiation | 10 Oct 2008 | 3,386 |
| 19 | Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis Simon Yona, Ki-Wook Kim, Yochai Wolf et al. · Immunity | 27 Dec 2012 | 3,364 |
| 20 | Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages Valerie A. Fadok, Dennis R. Voelker, Pearl A. Campbell et al. · The Journal of Immunology | Apr 1992 | 3,358 |
| 21 | A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes Philipp E. Scherer, Suzanne P. Williams, Michael Fogliano et al. · Journal of Biological Chemistry | Nov 1995 | 3,253 |
| 22 | Immunogenic cell death and DAMPs in cancer therapy Dmitri V. Krysko, Abhishek Dinkarnath Garg, Agnieszka Kaczmarek et al. · Nature reviews. Cancer | 15 Nov 2012 | 3,231 |
| 23 | Calreticulin exposure dictates the immunogenicity of cancer cell death Michel Obéid, Antoine Tesnière, François Ghiringhelli et al. · Nature Medicine | 24 Dec 2006 | 3,191 |
| 24 | Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. Valerie A. Fadok, Donna L. Bratton, Anatole Konowal et al. · Journal of Clinical Investigation | 15 Feb 1998 | 3,183 |
| 25 | Immunogenic cell death in cancer and infectious disease Lorenzo Galluzzi, Aitziber Buqué, Oliver Kepp et al. · Nature reviews. Immunology | 17 Oct 2016 | 3,145 |
| 26 | bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death Lawrence Boise, Maribel González‐García, C E Postema et al. · Cell | Aug 1993 | 3,130 |
| 27 | Macrophage Polarization Peter J. Murray · Annual Review of Physiology | 4 Nov 2016 | 3,090 |
| 28 | Two CD95 (APO‐1/Fas) signaling pathways Carsten Scaffidi, Simone Fulda, Anu Srinivasan et al. · The EMBO Journal | 16 Mar 1998 | 3,024 |
| 29 | MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES Alan A. Aderem, David M. Underhill · Annual Review of Immunology | Apr 1999 | 2,872 |
| 30 | Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. Séamus J. Martin, Chris P.M. Reutelingsperger, Anne J. McGahon et al. · The Journal of Experimental Medicine | Nov 1995 | 2,869 |
| 31 | Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis John S. Condeelis, Jeffrey W. Pollard · Cell | 2006 | 2,717 |
| 32 | Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto et al. · Nature | Jun 2017 | 2,668 |
| 33 | Macrophages as regulators of tumour immunity and immunotherapy David Glenn DeNardo, Brian Ruffell · Nature reviews. Immunology | 4 Feb 2019 | 2,661 |
| 34 | Apoptosis: controlled demolition at the cellular level Rebecca C. Taylor, Sean P. Cullen, Séamus J. Martin · Nature Reviews Molecular Cell Biology | 12 Dec 2007 | 2,623 |
| 35 | Met, metastasis, motility and more Carmen Birchmeier, Walter Birchmeier, Ermanno Gherardi et al. · Nature Reviews Molecular Cell Biology | Dec 2003 | 2,620 |
| 36 | Inhibition of death receptor signals by cellular FLIP Martin Irmler, Margot Thome, Michael Hahne et al. · Nature | 10 Jul 1997 | 2,581 |
| 37 | Non-canonical inflammasome activation targets caspase-11 Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi et al. · Nature | 16 Oct 2011 | 2,573 |
| 38 | Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis Gerrit Koopman, CP Reutelingsperger, GA Kuijten et al. · Blood | Sep 1994 | 2,466 |
| 39 | The Inflammasomes: Guardians of the Body Fabio Martinon, Annick Mayor, Jürg Tschopp · Annual Review of Immunology | 20 Mar 2009 | 2,450 |
| 40 | Caspases: killer proteases Donald W. Nicholson, Nancy A. Thornberry · Trends in Biochemical Sciences | Aug 1997 | 2,431 |
| 41 | Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma Ghassan K. Abou‐Alfa et al. · New England Journal of Medicine | 4 Jul 2018 | 2,386 |
| 42 | Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors Elisa Gomez Perdiguero, Kay Klapproth, Christian Schulz et al. · Nature | 2 Dec 2014 | 2,369 |
| 43 | Bcl-2 and the regulation of programmed cell death JC Reed · The Journal of Cell Biology | 1994 | 2,336 |
| 44 | PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity Sydney R. Gordon, Roy L. Maute, Ben W. Dulken et al. · Nature | May 2017 | 2,324 |
| 45 | Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia John C. Byrd et al. · New England Journal of Medicine | 19 Jun 2013 | 2,283 |
| 46 | Diversity, Mechanisms, and Significance of Macrophage Plasticity Massimo Locati, Graziella Curtale, Alberto Mantovani · Annual Review of Pathology Mechanisms of Disease | 17 Sep 2019 | 2,266 |
| 47 | mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity Shih‐Chin Cheng et al. · Science | 25 Sep 2014 | 2,266 |
| 48 | Macrophages in immunoregulation and therapeutics Shanze Chen, Abdullah F. U. H. Saeed, Quan Liu et al. · Signal Transduction and Targeted Therapy | 21 May 2023 | 2,233 |
| 49 | Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor. Frank Christian Kischkel, Stefan Hellbardt, Iris Behrmann et al. · The EMBO Journal | Nov 1995 | 2,188 |
| 50 | Targeting macrophages: therapeutic approaches in cancer Luca Cassetta, Jeffrey W. Pollard · Nature Reviews Drug Discovery | 26 Oct 2018 | 2,181 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.