Most cited papers in Physiological and biochemical adaptations
What are the most cited papers in Physiological and biochemical adaptations?
The most cited paper in Physiological and biochemical adaptations is "Oxidants, oxidative stress and the biology of ageing" (Toren Finkel, Nikki J. Holbrook, 2000), with 9,446 citations. Next come "TOWARD A METABOLIC THEORY OF ECOLOGY" (7,970) and "Exaptation—a Missing Term in the Science of Form" (5,178).
Showing 50 of 100 papers. Every paper with more than 1,048 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Oxidants, oxidative stress and the biology of ageing Toren Finkel, Nikki J. Holbrook · Nature | Nov 2000 | 9,446 |
| 2 | TOWARD A METABOLIC THEORY OF ECOLOGY James H. Brown, James F. Gillooly, Andrew P. Allen et al. · Ecology | Jul 2004 | 7,970 |
| 3 | Exaptation—a Missing Term in the Science of Form Stephen Jay Gould, Elisabeth S. Vrba · Paleobiology | 1982 | 5,178 |
| 4 | A General Model for the Origin of Allometric Scaling Laws in Biology Geoffrey B. West, James H. Brown, Brian Joseph Enquist · Science | 4 Apr 1997 | 5,083 |
| 5 | HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology Martin E. Feder, Gretchen E. Hofmann · Annual Review of Physiology | Mar 1999 | 4,360 |
| 6 | The stress response in fish Sjoerd E. Wendelaar Bonga · Physiological Reviews | Jul 1997 | 4,180 |
| 7 | Impacts of climate warming on terrestrial ectotherms across latitude Curtis Anthony Deutsch, Joshua J. Tewksbury, Raymond B. Huey et al. · Proceedings of the National Academy of Sciences | 5 May 2008 | 3,891 |
| 8 | Effects of Size and Temperature on Metabolic Rate James F. Gillooly, James H. Brown, Geoffrey B. West et al. · Science | 21 Sep 2001 | 3,887 |
| 9 | Climate change and evolutionary adaptation Ary A. Hoffmann, Carla M. Sgrò · Nature | Feb 2011 | 3,371 |
| 10 | Nitric oxide synthases: Roles, tolls, and controls Carl Nathan, Q W Xie · Cell | Sep 1994 | 2,947 |
| 11 | The Multifunctional Fish Gill: Dominant Site of Gas Exchange, Osmoregulation, Acid-Base Regulation, and Excretion of Nitrogenous Waste David H. Evans, Peter M. Piermarini, Keith Patrick Choe · Physiological Reviews | 23 Dec 2004 | 2,938 |
| 12 | Herbivory in global climate change research: direct effects of rising temperature on insect herbivores Jeffery S. Bale, Gregory J. Masters, I. D. Hodkinson et al. · Global Change Biology | 2002 | 2,786 |
| 13 | Environmentally induced oxidative stress in aquatic animals Volodymyr I. Lushchak · Aquatic Toxicology | 26 Oct 2010 | 2,711 |
| 14 | Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate Hanspeter Streb, R.F. Irvine, Michael John Berridge et al. · Nature | Nov 1983 | 2,611 |
| 15 | Cloning and expression of a cDNA encoding an endothelin receptor Hiroshi Arai, Seiji Hori, Ichiro Aramori et al. · Nature | Dec 1990 | 2,597 |
| 16 | Physiology and Climate Change Hans‐Otto Pörtner, Anthony P. Farrell · Science | 30 Oct 2008 | 2,554 |
| 17 | Stress in Fishes: A Diversity of Responses with Particular Reference to Changes in Circulating Corticosteroids BRUCE A. BARTON · Integrative and Comparative Biology | Jul 2002 | 2,511 |
| 18 | Heatmapper: web-enabled heat mapping for all Sasha Babicki, David Arndt, Ana Marcu et al. · Nucleic Acids Research | 17 May 2016 | 2,475 |
| 19 | Hsp90 as a capacitor for morphological evolution Suzanne L. Rutherford, Susan Lee Lindquist · Nature | Nov 1998 | 2,347 |
| 20 | Cortisol in teleosts: dynamics, mechanisms of action, and metabolic regulation Thomas P. Mommsen, Mathilakath M. Vijayan, Thomas W. Moon · Reviews in Fish Biology and Fisheries | Sep 1999 | 2,332 |
| 21 | A new puffing pattern induced by temperature shock and DNP in drosophila Ferruccio Ritossa · Cellular and Molecular Life Sciences | Dec 1962 | 2,082 |
| 22 | Appearance of Water Channels in Xenopus Oocytes Expressing Red Cell CHIP28 Protein Gregory M. Preston, Tiziana Piazza Carroll, William B. Guggino et al. · Science | 17 Apr 1992 | 2,078 |
| 23 | Climate Change Affects Marine Fishes Through the Oxygen Limitation of Thermal Tolerance Hans‐Otto Pörtner, Rainer Knust · Science | 5 Jan 2007 | 2,052 |
| 24 | Thermal Adaptation: A Theoretical and Empirical Synthesis Michael J. Angilletta | 2009 | 2,048 |
| 25 | Cellular energy utilization and molecular origin of standard metabolic rate in mammals David F. S. Rolfe, Guy Charles Brown · Physiological Reviews | Jul 1997 | 2,037 |
| 26 | IMMUNIZATION OF DISSOCIATED SPLEEN CELL CULTURES FROM NORMAL MICE Robert I. Mishell, Richard W Dutton · The Journal of Experimental Medicine | Sep 1967 | 2,036 |
| 27 | Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators Richard I. Morimoto · Genes & Development | 15 Dec 1998 | 1,938 |
| 28 | The physiology of climate change: how potentials for acclimatization and genetic adaptation will determine ‘winners’ and ‘losers’ George N. Somero · Journal of Experimental Biology | 26 Feb 2010 | 1,919 |
| 29 | Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals James N. Dumont · Journal of Morphology | Feb 1972 | 1,856 |
| 30 | Angiotensin-converting enzyme 2 is an essential regulator of heart function Michael A. Crackower, Renu Sarao, Gavin Y. Oudit et al. · Nature | Jun 2002 | 1,775 |
| 31 | The Fourth Dimension of Life: Fractal Geometry and Allometric Scaling of Organisms Geoffrey B. West, James H. Brown, Brian Joseph Enquist · Science | 4 Jun 1999 | 1,751 |
| 32 | Global warming benefits the small in aquatic ecosystems Martín Daufresne, Kathrin Lengfellner, Ulrich Sommer · Proceedings of the National Academy of Sciences | 21 Jul 2009 | 1,706 |
| 33 | EFFECTS OF SIZE AND CONCENTRATION OF FOOD PARTICLES ON THE FEEDING BEHAVIOR OF THE MARINE PLANKTONIC COPEPOD CALANUS PACIFICUS 1 Bruch W. Frost · Limnology and Oceanography | Nov 1972 | 1,672 |
| 34 | Thermal tolerance and the global redistribution of animals Jennifer M. Sunday, Amanda E. Bates, Nicholas K. Dulvy · Nature Climate Change | 25 May 2012 | 1,624 |
| 35 | The physiology/life-history nexus Robert E. Ricklefs, Martin C. Wikelski · Trends in Ecology & Evolution | Oct 2002 | 1,621 |
| 36 | The Physiology of Life History Trade-Offs in Animals Anthony J. Zera, Lawrence G. Harshman · Annual Review of Ecology and Systematics | Nov 2001 | 1,600 |
| 37 | Integrating Thermal Physiology and Ecology of Ectotherms: A Discussion of Approaches Raymond B. Huey, R. D. Stevenson · American Zoologist | Feb 1979 | 1,572 |
| 38 | Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing Robert D. Guzy, Beatrice E. Hoyos, Emmanuel Robin et al. · Cell Metabolism | Jun 2005 | 1,547 |
| 39 | Energy homeostasis as an integrative tool for assessing limits of environmental stress tolerance in aquatic invertebrates Inna M. Sokolova, Markus Frederich, Rita Bagwe et al. · Marine Environmental Research | 30 Apr 2012 | 1,492 |
| 40 | S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds. Jonathan S. Stamler, Daniel I. Simon, John A. Osborne et al. · Proceedings of the National Academy of Sciences | 1992 | 1,488 |
| 41 | Physiology of Cell Volume Regulation in Vertebrates Else Kay Hoffmann, Ian Henry Lambert, Stine F. Pedersen · Physiological Reviews | 2009 | 1,476 |
| 42 | Oxygen- and capacity-limitation of thermal tolerance: a matrix for integrating climate-related stressor effects in marine ecosystems Hans‐Otto Pörtner · Journal of Experimental Biology | 26 Feb 2010 | 1,475 |
| 43 | Predicting organismal vulnerability to climate warming: roles of behaviour, physiology and adaptation Raymond B. Huey, Michael Kearney, Andrew K. Krockenberger et al. · Philosophical Transactions of the Royal Society B Biological Sciences | 7 May 2012 | 1,469 |
| 44 | Invited Review: Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance K. C. Kregel · Journal of Applied Physiology | May 2002 | 1,461 |
| 45 | Climate variations and the physiological basis of temperature dependent biogeography: systemic to molecular hierarchy of thermal tolerance in animals Hans‐Otto Pörtner · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology | Aug 2002 | 1,445 |
| 46 | Control of Aragonite or Calcite Polymorphism by Mollusk Shell Macromolecules Giuseppe Falini, Shira Albeck, Steve Weiner et al. · Science | 5 Jan 1996 | 1,436 |
| 47 | Scaling of metabolic rate with body mass and temperature in teleost fish Andrew Clarke, Nadine M. Johnston · Journal of Animal Ecology | Sep 1999 | 1,431 |
| 48 | The evolutionary and ecological role of heat shock proteins Jesper Givskov Sørensen, Torsten Nygaard Kristensen, Volker Loeschcke · Ecology Letters | 30 Sep 2003 | 1,430 |
| 49 | Hsp90 as a capacitor of phenotypic variation Christine Queitsch, Todd A. Sangster, Susan Lee Lindquist · Nature | 12 May 2002 | 1,428 |
| 50 | The evolution of thermal physiology in ectotherms Michael J. Angilletta, Peter H. Niewiarowski, Carlos A. Navas · Journal of Thermal Biology | Aug 2002 | 1,425 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.