Most cited papers in Phytochemical Studies and Bioactivities
What are the most cited papers in Phytochemical Studies and Bioactivities?
The most cited paper in Phytochemical Studies and Bioactivities is "NMR Spectroscopy in the structural elucidation of oligosaccharides and glycosides" (Pawan Kumar Agrawal, 1992), with 1,450 citations. Next come "Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d‐tubocurarine" (1,146) and "Fatty Acid and Polar Lipid Composition in the Classification of Cellulomonas, Oerskovia and Related Taxa" (942).
Showing 50 of 100 papers. Every paper with more than 218 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | NMR Spectroscopy in the structural elucidation of oligosaccharides and glycosides Pawan Kumar Agrawal · Phytochemistry | Oct 1992 | 1,450 |
| 2 | Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d‐tubocurarine Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics | Mar 1979 | 1,146 |
| 3 | Fatty Acid and Polar Lipid Composition in the Classification of Cellulomonas, Oerskovia and Related Taxa David E. Minnikin, M.D. Collins, Michael Goodfellow · Journal of Applied Bacteriology | Aug 1979 | 942 |
| 4 | Saponins, classification and occurrence in the plant kingdom Jean‐Paul Vincken, Lynn Heng, C.P.G.M. de Groot et al. · Phytochemistry | 5 Dec 2006 | 799 |
| 5 | Reduction of Serum Cholesterol with Sitostanol-Ester Margarine in a Mildly Hypercholesterolemic Population Tatu A. Miettinen, Pekka Puska, Helena K. Gylling et al. · New England Journal of Medicine | 16 Nov 1995 | 745 |
| 6 | Saponins as cytotoxic agents: a review Irma Podolak, Agnieszka Galanty, Danuta Sobolewska · Phytochemistry Reviews | 24 Jun 2010 | 706 |
| 7 | STUDIES ON THE GRAM-NEGATIVE CELL WALL, I. EVIDENCE FOR THE ROLE OF 2-KETO-3-DEOXYOCTONATE IN THE LIPOPOLYSACCHARIDE OF SALMONELLA TYPHIMURIUM Mary Osborn · Proceedings of the National Academy of Sciences | Sep 1963 | 694 |
| 8 | Goji (Lycium barbarumandL. chinense): Phytochemistry, Pharmacology and Safety in the Perspective of Traditional Uses and Recent Popularity Olivier Potterat · Planta Medica | 20 Oct 2009 | 652 |
| 9 | Glycosaminoglycans and their proteoglycans: host‐associated molecular patterns for initiation and modulation of inflammation Kristen R. Taylor, Richard L. Gallo · The FASEB Journal | 2006 | 643 |
| 10 | The chemistry and biological significance of saponins in foods and feedingstuffs KEITH R. PRICE, Ian T. Johnson, G. R. Fenwick et al. · C R C Critical Reviews in Food Science and Nutrition | 1987 | 621 |
| 11 | Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors Aviv Gazit, Pnina Yaish, Chaim Gilon et al. · Journal of Medicinal Chemistry | Oct 1989 | 606 |
| 12 | Prokaryotic Hopanoids and other Polyterpenoid Sterol Surrogates Guy Ourisson, Michel Rohmer, Karl Poralla · Annual Review of Microbiology | Oct 1987 | 579 |
| 13 | Carbon-13 NMR spectroscopy of steroidal sapogenins and steroidal saponins Pawan Kumar Agrawal, D. C. Jain, Rajesh Kashi Prakash Gupta et al. · Phytochemistry | Oct 1985 | 577 |
| 14 | A Rice Brassinosteroid-Deficient Mutant, ebisu dwarf ( d2 ), Is Caused by a Loss of Function of a New Member of Cytochrome P450 Zhi Hong, Miyako Ueguchi‐Tanaka, Kazuto Umemura et al. · The Plant Cell | 13 Nov 2003 | 575 |
| 15 | Action of Saponin on Biological Cell Membranes A. D. Bangham, Robert W. Horne · Nature | Dec 1962 | 511 |
| 16 | Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial Uwe R. Juergens, Uwe Dethlefsen, Gratiana Steinkamp et al. · Respiratory Medicine | Mar 2003 | 484 |
| 17 | Review of the mechanism of cell death resulting from streptozotocin challenge in experimental animals, its practical use and potential risk to humans Chinedum Ogbonnaya Eleazu, Kate Chinedum Eleazu, S Chukwuma et al. · Journal of Diabetes & Metabolic Disorders | 23 Dec 2013 | 460 |
| 18 | Simple indole alkaloids and those with a nonrearranged monoterpenoid unit Minoru Ishikura, Koji Yamada, Takumi Abe · Natural Product Reports | 2010 | 457 |
| 19 | Further characterization of the antithrombin-binding sequence in heparin L Thunberg, Gudrun Bäckström, Ulf Lindahl · Carbohydrate Research | 1982 | 454 |
| 20 | Constituents from Salvia Species and Their Biological Activities Yibing Wu, Zhi‐Yu Ni, Qing‐Wen Shi et al. · Chemical Reviews | 11 Sep 2012 | 441 |
| 21 | Chemical study and medical application of saponins as anti-cancer agents Shuli Man, Wenyuan Gao, Yanjun Zhang et al. · Fitoterapia | 14 Jun 2010 | 438 |
| 22 | Isolation and identification Vladimir A. Khripach, Vladimir N. Zhabinskii, Annemarie Groot · Elsevier eBooks | 1999 | 423 |
| 23 | Antioxidant activity of Smilax excelsa L. leaf extracts Nurten Özsoy, Ayşe Can, Refiye Yanardağ et al. · Food Chemistry | 21 Feb 2008 | 407 |
| 24 | Insight into the evolution of the Solanaceae from the parental genomes of Petunia hybrida Aureliano Bombarely et al. · Nature Plants | 27 May 2016 | 404 |
| 25 | Flavanones: Citrus phytochemical with health‐promoting properties Davide Barreca, Giuseppe Gattuso, Ersilia Bellocco et al. · BioFactors | 12 May 2017 | 387 |
| 26 | The genus Polygonatum : A review of ethnopharmacology, phytochemistry and pharmacology Ping Zhao, Chengcheng Zhao, Xia Li et al. · Journal of Ethnopharmacology | 12 Dec 2017 | 386 |
| 27 | Dragon's blood: Botany, chemistry and therapeutic uses Deepika Gupta, Bruce H. Bleakley, Rajinder Kumar Gupta · Journal of Ethnopharmacology | 4 Dec 2007 | 386 |
| 28 | Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: A review Longfei Lin, Boran Ni, Hongmei Lin et al. · Journal of Ethnopharmacology | 18 Nov 2014 | 383 |
| 29 | Direct Catalytic Asymmetric Aldol Reaction Naoki Yoshikawa, Yoichi M. A. Yamada, Jagattaran Das et al. · Journal of the American Chemical Society | 17 Apr 1999 | 374 |
| 30 | Hawkinsin A. M. Gressner, O. A. Gressner · Springer Reference Medizin | 2019 | 368 |
| 31 | Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats Kalamegam Gauthaman, P. Ganesan Adaikan, R. N. V. Prasad · Life Sciences | Aug 2002 | 365 |
| 32 | Cardiovascular actions and therapeutic potential of tanshinone IIA Si Gao, Zhiping Liu, Hong Li et al. · Atherosclerosis | 5 Jul 2011 | 363 |
| 33 | Phytopharmacological overview of Tribulus terrestris Saurabh P. Chhatre, Tanuja Manoj Nesari, Divya M. Kanchan et al. · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review | 2014 | 356 |
| 34 | Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells Sudheer Kumar Mantena, Som Datta Sharma, Santosh K. Katiyar · Molecular Cancer Therapeutics | Feb 2006 | 351 |
| 35 | Hepatocyte Nuclear Factor 1α Plays a Critical Role in PCSK9 Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine Hai Li, Bin Dong, Sahng Wook Park et al. · Journal of Biological Chemistry | 17 Aug 2009 | 348 |
| 36 | Citri Reticulatae Pericarpium (Chenpi): Botany, ethnopharmacology, phytochemistry, and pharmacology of a frequently used traditional Chinese medicine Xin Yu, Shuang Sun, Yuyan Guo et al. · Journal of Ethnopharmacology | 6 Apr 2018 | 344 |
| 37 | Astragalus polysaccharide: a review of its immunomodulatory effect Chunxiao Li, Ying Liu, Yuzhen Zhang et al. · Archives of Pharmacal Research | Jun 2022 | 336 |
| 38 | Bioavailability Is Improved by Enzymatic Modification of the Citrus Flavonoid Hesperidin in Humans: A Randomized, Double-Blind, Crossover Trial Inge Lise F. Nielsen, Winnie Siew Swee Chee, Lea Poulsen et al. · Journal of Nutrition | Feb 2006 | 332 |
| 39 | Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors Ian E. Krop, Tim Demuth, Tina Guthrie et al. · Journal of Clinical Oncology | May 2012 | 320 |
| 40 | Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies Angela Pirillo, Alberico Luigi Catapano · Atherosclerosis | 2 Oct 2015 | 309 |
| 41 | Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection Jennifer Hui‐Chun Ho, Chuang-Ye Hong · Journal of Biomedical Science | 2011 | 300 |
| 42 | Steroids and Squalene in Methylococcus capsulatus grown on Methane C. W. BIRD, James M. Lynch, F. J. PIRT et al. · Nature | Apr 1971 | 293 |
| 43 | Countercurrent Separation of Natural Products: An Update J. Brent Friesen, James B. McAlpine, Shao‐Nong Chen et al. · Journal of Natural Products | 15 Jul 2015 | 293 |
| 44 | Determination of anthocyanins, flavonoids and phenolic acids in potatoes. I: Coloured cultivars ofSolanum tuberosum L Christine E Lewis, John Roger Walker, Jane E. Lancaster et al. · Journal of the Science of Food and Agriculture | May 1998 | 292 |
| 45 | Plant profile, phytochemistry and pharmacology of Asparagus racemosus (Shatavari): A review Shashi Alok, Sanjay Jain, Amita Verma et al. · Asian Pacific Journal of Tropical Disease | 26 Mar 2013 | 292 |
| 46 | Diosgenin, a Steroid Saponin of Trigonella foenum graecum (Fenugreek), Inhibits Azoxymethane-Induced Aberrant Crypt Foci Formation in F344 Rats and Induces Apoptosis in HT-29 Human Colon Cancer Cells Jayadev Raju, Jagan M.R. Patlolla, Malisetty Venkat Swamy et al. · Cancer Epidemiology Biomarkers & Prevention | Aug 2004 | 291 |
| 47 | The Dioscorea Genus (Yam)—An Appraisal of Nutritional and Therapeutic Potentials Jude Ejikeme Obidiegwu, Jessica B. Lyons, Cynthia Adaku Chilaka · Foods | 16 Sep 2020 | 288 |
| 48 | The sacred lotus (Nelumbo nucifera)– phytochemical and therapeutic profile Pulok Kumar Mukherjee, Debajyoti Mukherjee, Amal K. Maji et al. · Journal of Pharmacy and Pharmacology | Apr 2009 | 285 |
| 49 | Salvia divinorum and salvinorin A: new pharmacologic findings Daniel J. Siebert · Journal of Ethnopharmacology | Jun 1994 | 282 |
| 50 | N-containing sugars fromMorus alba and their glycosidase inhibitory activities Naoki Asano, Kengo Oseki, Emiko Tomioka et al. · Carbohydrate Research | Jun 1994 | 276 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.