Science Explorer Back to mapMap

Most cited papers in Plant biochemistry and biosynthesis

Plant biochemistry and biosynthesis

What are the most cited papers in Plant biochemistry and biosynthesis?

The most cited paper in Plant biochemistry and biosynthesis is "Extended-Connectivity Fingerprints" (David O. Williams Rogers, Mathew Hahn, 2010), with 7,989 citations. Next come "An integrated procedure for the extraction of bacterial isoprenoid quinones and polar lipids" (5,534) and "Regulation of the mevalonate pathway" (5,449).

Showing 50 of 100 papers. Every paper with more than 1,189 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Extended-Connectivity Fingerprints David O. Williams Rogers, Mathew Hahn · Journal of Chemical Information and Modeling 28 Apr 2010 7,989
2 An integrated procedure for the extraction of bacterial isoprenoid quinones and polar lipids David E. Minnikin, Anthony G. O’Donnell, Michael Goodfellow et al. · Journal of Microbiological Methods Jul 1984 5,534
3 Regulation of the mevalonate pathway Joseph L. Goldstein, Michael S. Brown · Nature Feb 1990 5,449
4 Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. Marco T. Castagna, Yoshimi Takai, Kozo Kaibuchi et al. · Journal of Biological Chemistry Open access Jul 1982 4,765
5 ChEMBL: a large-scale bioactivity database for drug discovery Anna Gaulton, Louisa J. Bellis, A. Patrícia Bento et al. · Nucleic Acids Research Open access 23 Sep 2011 4,581
6 wannier90: A tool for obtaining maximally-localised Wannier functions Arash A. Mostofi, Jonathan R. Yates, Young‐Su Lee et al. · Computer Physics Communications Open access 28 Dec 2007 4,306
7 The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla Olivier Jaillon et al. · Nature Open access 26 Aug 2007 3,997
8 Antioxidant Activity of Plant Extracts Containing Phenolic Compounds Marja P. Kähkönen, Anu Hopia, Heikki J. Vuorela et al. · Journal of Agricultural and Food Chemistry 24 Sep 1999 3,862
9 Stress-Induced Phenylpropanoid Metabolism. Richard Arthur Dixon, Nancy L. Paiva · The Plant Cell Open access Jul 1995 3,827
10 Flavonoid Biosynthesis. A Colorful Model for Genetics, Biochemistry, Cell Biology, and Biotechnology A. Winkel · PLANT PHYSIOLOGY Jun 2001 3,789
11 A simple and efficient method for isolating RNA from pine trees Shujun Chang, Jeff Puryear, John W. G. CAIRNEY · Plant Molecular Biology Reporter Jun 1993 3,633
12 Improved protein structure prediction using potentials from deep learning Andrew Senior, Richard Evans, John Jumper et al. · Nature Open access 15 Jan 2020 3,622
13 The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins William H. Landschulz, Peter F. Johnson, Steven Lanier McKnight · Science 24 Jun 1988 3,521
14 Metabolomics — the link between genotypes and phenotypes Oliver Fiehn Book chapter 2002 3,177
15 Phenylpropanoid Biosynthesis Thomas Vogt · Molecular Plant Open access 24 Dec 2009 3,163
16 Discovery and resupply of pharmacologically active plant-derived natural products: A review Atanas G. Atanasov, Birgit Waltenberger, Eva‐Maria Pferschy‐Wenzig et al. · Biotechnology Advances Open access 15 Aug 2015 2,927
17 Production of the antimalarial drug precursor artemisinic acid in engineered yeast Dae‐Kyun Ro, Eric M. Paradise, Mario Ouellet et al. · Nature 13 Apr 2006 2,875
18 BRANCH SUPPORT AND TREE STABILITY Ka ̊re Bremer · Cladistics Sep 1994 2,841
19 JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling Bryan C. Thines, Leron Katsir, Maeli Melotto et al. · Nature 18 Jul 2007 2,597
20 Insect Fat Body: Energy, Metabolism, and Regulation Estela L. Arrese, José L. Soulages · Annual Review of Entomology ReviewOpen access 2 Sep 2009 2,589
21 Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications Mar 1986 2,475
22 Chemistry and Biochemistry of Dietary Polyphenols Rong Tsao · Nutrients Open access 10 Dec 2010 2,419
23 Isochorismate synthase is required to synthesize salicylic acid for plant defence Mary C. Wildermuth, Julia Dewdney, Gang Wu et al. · Nature 29 Nov 2001 2,410
24 Gas chromatography mass spectrometry–based metabolite profiling in plants Jan Lisec, Nicolas Schauer, Joachim Kopka et al. · Nature Protocols Jun 2006 2,237
25 The function of terpene natural products in the natural world Jonathan Gershenzon, Natalia Dudareva · Nature Chemical Biology 18 Jun 2007 2,211
26 Flavonoids as antioxidants in plants: Location and functional significance Giovanni Agati, Elisa Azzarello, Susanna Pollastri et al. · Plant Science 11 Aug 2012 2,171
27 The genome of the domesticated apple (Malus × domestica Borkh.) Riccardo Velasco et al. · Nature Genetics 27 Aug 2010 2,158
28 Metabolite profiling for plant functional genomics Oliver Fiehn, Joachim Kopka, Peter Dörmann et al. · Nature Biotechnology Nov 2000 2,147
29 High-level semi-synthetic production of the potent antimalarial artemisinin Christopher J. Paddon et al. · Nature Open access Apr 2013 2,122
30 Regulation of the anthocyanin biosynthetic pathway by the TTG1/bHLH/Myb transcriptional complex in Arabidopsis seedlings Antonio G. González, Mingzhe Zhao, John M. Leavitt et al. · The Plant Journal Open access 23 Nov 2007 2,055
31 Recent advances in extraction of nutraceuticals from plants Lijun Wang, Curtis L. Weller · Trends in Food Science & Technology 27 Jan 2006 2,033
32 Elicitor signal transduction leading to production of plant secondary metabolites Jian Hua Zhao, Lawrence C. Davis, Robert Verpoorte · Biotechnology Advances 15 Mar 2005 1,956
33 Phytochemicals: Extraction, Isolation, and Identification of Bioactive Compounds from Plant Extracts Ammar B. Altemimi, Naoufal Lakhssassi, Azam Baharlouei et al. · Plants Open access 22 Sep 2017 1,954
34 antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters Tilmann Weber, Kai Blin, Srikanth Duddela et al. · Nucleic Acids Research Open access 6 May 2015 1,937
35 Flavonoids: biosynthesis, biological functions, and biotechnological applications Marı́a Lorena Falcone Ferreyra, Sebastián Pablo Rius, Paula Casati · Frontiers in Plant Science Open access 2012 1,896
36 Jasmonates: An Update on Biosynthesis, Signal Transduction and Action in Plant Stress Response, Growth and Development Claus H. Wasternack · Annals of Botany Open access 18 May 2007 1,851
37 Natural products in drug discovery Alan L. Harvey · Drug Discovery Today 23 Aug 2008 1,843
38 SwissTargetPrediction: a web server for target prediction of bioactive small molecules David Gfeller, Aurélien Grosdidier, Matthias Wirth et al. · Nucleic Acids Research Open access 3 May 2014 1,839
39 All ras proteins are polyisoprenylated but only some are palmitoylated John F. Hancock, Anthony I. Magee, Julie E. Childs et al. · Cell Jun 1989 1,825
40 Natural products and plant disease resistance Richard Arthur Dixon · Nature Jun 2001 1,807
41 Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions Nai‐Qian Dong, Hong‐Xuan Lin · Journal of Integrative Plant Biology Open access 16 Dec 2020 1,793
42 Response of Plant Secondary Metabolites to Environmental Factors Yang Li, Kuishan Wen, Xiao Ruan et al. · Molecules Open access 27 Mar 2018 1,762
43 Engineering a mevalonate pathway in Escherichia coli for production of terpenoids Vincent J. J. Martin, Douglas J. Pitera, Sydnor T. Withers et al. · Nature Biotechnology 30 May 2003 1,762
44 Biosynthesis, function and metabolic engineering of plant volatile organic compounds Natalia Dudareva, Antje Klempien, Joëlle K. Mühlemann et al. · New Phytologist 6 Feb 2013 1,734
45 Crystal structure of spinach major light-harvesting complex at 2.72 Å resolution Zhenfeng Liu, Hanchi Yan, Kebin Wang et al. · Nature Mar 2004 1,725
46 Flavonoids: a colorful model for the regulation and evolution of biochemical pathways Ronald E. Koes, Walter Verweij, Francesca M. Quattrocchio · Trends in Plant Science Review 29 Mar 2005 1,689
47 Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli Parayil Kumaran Ajikumar, Wenhai Xiao, Keith E. J. Tyo et al. · Science 30 Sep 2010 1,666
48 Structural Mechanism for Statin Inhibition of HMG-CoA Reductase Eva S. Istvan, J. Deisenhofer · Science 11 May 2001 1,666
49 Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences Open access Jul 1980 1,638
50 Control of Chemical Reactions by Feedback-Optimized Phase-Shaped Femtosecond Laser Pulses Andreas Assion, Thomas Baumert, Michael Bergt et al. · Science 30 Oct 1998 1,636

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.