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Most cited papers in Plant-Derived Bioactive Compounds

What are the most cited papers in Plant-Derived Bioactive Compounds?

The most cited paper in Plant-Derived Bioactive Compounds is "Determination of protein: A modification of the lowry method that gives a linear photometric response" (Edward F. Hartree, 1972), with 5,552 citations. Next come "Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization" (3,322) and "A general method for isolation of high molecular weight DNA from eukaryotes" (2,814).

Showing 50 of 100 papers. Every paper with more than 184 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Determination of protein: A modification of the lowry method that gives a linear photometric response Edward F. Hartree · Analytical Biochemistry Aug 1972 5,552
2 Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization Zoltán Takáts, Justin M. Wiseman, Bogdan Gologan et al. · Science 14 Oct 2004 3,322
3 A general method for isolation of high molecular weight DNA from eukaryotes Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research Open access Sep 1976 2,814
4 Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes Johanna R. Rochester, Ashley L. Bolden · Environmental Health Perspectives ReviewOpen access 16 Mar 2015 1,536
5 Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol. Abraham Abuchowski, Theo Van Es, Nicholas C. Palczuk et al. · Journal of Biological Chemistry Open access Jun 1977 1,363
6 Gravimetric determination of tannins and their correlations with chemical and protein precipitation methods Harinder P. S. Makkar, Michael Blümmel, Norbert K. Borowy et al. · Journal of the Science of Food and Agriculture 1993 1,222
7 Polyphenolic Substance of Mytilus edulis : Novel Adhesive Containing L-Dopa and Hydroxyproline J. Herbert Waite, Marvin L. Tanzer · Science 29 May 1981 1,058
8 The colorimetric micro-determination of long-chain fatty acids W. G. Duncombe · Biochemical Journal Open access Jul 1963 978
9 Uptake and Cytotoxicity of Chitosan Molecules and Nanoparticles: Effects of Molecular Weight and Degree of Deacetylation Min Huang, Eugene Khor, Lee Yong Lim · Pharmaceutical Research Feb 2004 854
10 THE CHROMATOGRAPHIC IDENTIFICATION OF SOME BIOLOGICALLY IMPORTANT PHOSPHATE ESTERS Robert S. Bandurski, Bernard Axelrod · Journal of Biological Chemistry Open access Nov 1951 738
11 Role of l -3,4-Dihydroxyphenylalanine in Mussel Adhesive Proteins Miaoer Yu, Jungyeon Hwang, Timothy J. Deming · Journal of the American Chemical Society Jun 1999 633
12 Tannic Acid with Antiviral and Antibacterial Activity as A Promising Component of Biomaterials—A Minireview Beata Kaczmarek · Materials Open access 20 Jul 2020 627
13 A new colorimetric technique for the estimation of vitamin C using Folin phenol reagent S.K. Jagota, H. M. Dani · Analytical Biochemistry Nov 1982 622
14 Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil Katherine A. Hammer, Christine F Carson, Thomas Victor Riley · Journal of Applied Microbiology 9 Sep 2003 512
15 Coumarins and Coumarin-Related Compounds in Pharmacotherapy of Cancer Esra Küpeli Akkol, Yasin Genç, Büşra Karpuz et al. · Cancers Open access 19 Jul 2020 492
16 Contact urticaria to rubber A.F. NUTTER · British Journal of Dermatology Nov 1979 472
17 THE QUANTITATIVE HISTOCHEMISTRY OF THE BRAIN Oliver H. Lowry · Journal of Histochemistry & Cytochemistry Nov 1953 467
18 NEW PHOTOLABELING AND CROSSLINKING METHODS Josef Brunner · Annual Review of Biochemistry Jun 1993 451
19 Dietary polyphenol intake in Europe: the European Prospective Investigation into Cancer and Nutrition (EPIC) study Raúl Zamora‐Ros et al. · European Journal of Nutrition Open access 16 Jun 2015 447
20 The formation of fibrils from collagen solutions 1. The effect of experimental conditions: kinetic and electron-microscope studies Geoffrey C. Wood, Madeline K. Keech · Biochemical Journal Open access Jun 1960 442
21 Phthalate Exposure and Human Semen Parameters Susan M. Duty, Manori J. Silva, Dana Boyd Barr et al. · Epidemiology May 2003 436
22 Incidence of Cancer and Mortality Following α-Tocopherol and β-Carotene Supplementation Jarmo R. K. Virtamo, Pirjo Pietinen, Jussi K. Huttunen et al. · JAMA 23 Jul 2003 428
23 Estrogen Receptor in a Human Cell Line (MCF-7) from Breast Carcinoma Samuel Carroll Brooks, Elizabeth R. Locke, Herbert D. Soule · Journal of Biological Chemistry Open access Sep 1973 415
24 A method using 3-O-methyl-D-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture Rolf F. Kletzien, Michael W. Pariza, Joyce E. Becker et al. · Analytical Biochemistry Oct 1975 407
25 In Situ Estrogen Production via the Estrone Sulfatase Pathway in Breast Tumors: Relative Importance versus the Aromatase Pathway* Steven J. Santner, Peter D. Feil, Richard J. Santen · The Journal of Clinical Endocrinology & Metabolism Jul 1984 407
26 Adsorption of chromium from aqueous solutions by maple sawdust Li Yu, Shyam S. Shukla, Kenneth L. Dorris et al. · Journal of Hazardous Materials 19 May 2003 406
27 A comparison between two brine shrimp assays to detect in vitrocytotoxicity in marine natural products José Luís Carballo, Zaira L Hernández-Inda, Pilar Pérez et al. · BMC Biotechnology Open access 23 Sep 2002 403
28 Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development Robert Verpoorte · Drug Discovery Today May 1998 396
29 (−)-Epigallocatechin Gallate and Polyphenon E Inhibit Growth and Activation of the Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor-2 Signaling Pathways in Human Colon Cancer Cells Masahito Shimizu, Atsuko Deguchi, Jin T. E. Lim et al. · Clinical Cancer Research Open access Apr 2005 348
30 Oestrogen-responsive human breast cancer in long term tissue culture Marc E. Lippman, GAIL A. BOLAN · Nature Aug 1975 336
31 Leaf Size, Sapling Allometry, and Corner's Rules: Phylogeny and Correlated Evolution in Maples (Acer) David D. Ackerly, Michael J. Donoghue · The American Naturalist Dec 1998 332
32 Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Lillian Barros, Eliana Pereira, Ricardo Costa Calhelha et al. · Journal of Functional Foods Open access 12 Aug 2013 330
33 Diagnosis and Treatment of Maple Syrup Disease: A Study of 36 Patients D. Holmes Morton, Kevin A. Strauss, Donna L. Robinson et al. · PEDIATRICS Jun 2002 326
34 Choosing appropriate methods and standards for assaying tannin Ann E Hagerman, Larry G. Butler · Journal of Chemical Ecology Jun 1989 326
35 Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis Xiaoqian Liu, Gustavo C Machado, Jillian Peta Eyles et al. · British Journal of Sports Medicine Review 10 Oct 2017 315
36 In vitro anticancer screening of South African plants Gerda Fouché, GM Cragg, Priyen Pillay et al. · Journal of Ethnopharmacology 17 Jul 2008 315
37 Phthalate Concentrations and Dietary Exposure from Food Purchased in New York State Arnold J. Schecter, Matthew Lorber, Ying Guo et al. · Environmental Health Perspectives Open access 6 Mar 2013 314
38 Different extraction methods of biologically active components from propolis: a preliminary study Boryana Trusheva, Dorina Trunkova, Vassya Stefanova Bankova · Chemistry Central Journal Open access 7 Jun 2007 305
39 A STUDY OF THE METABOLISM OF THEOBROMINE, THEOPHYLLINE, AND CAFFEINE IN MAN Herbert H. Cornish, Adam A. Christman · Journal of Biological Chemistry Open access Sep 1957 304
40 Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol Regina Cencic, Marilyn Carrier, Gabriela Galicia-Vázquez et al. · PLoS ONE Open access 28 Apr 2009 297
41 Treatment of advanced breast cancer with sterically stabilized liposomal doxorubicin: results of a multicenter phase II trial. Malcolm Ranson, J. DONALD CARMICHAEL, Kenneth John O'Byrne et al. · Journal of Clinical Oncology Oct 1997 297
42 Selective removal of albumin from plasma by affinity chromatography James W. Travis, Ralph Pannell · Clinica Chimica Acta Nov 1973 296
43 Homing of liposomes to target cells E. Gregory Gregoriadis, Diane Neerunjun · Biochemical and Biophysical Research Communications Jul 1975 294
44 Solvent effects on phytochemical constituent profiles and antioxidant activities, using four different extraction formulations for analysis of Bucida buceras L. and Phoradendron californicum Simon Bernard Iloki Assanga, Lidianys María Lewis Luján, Claudia Lara-Espinoza et al. · BMC Research Notes Open access 31 Aug 2015 290
45 Structural Characterization of Natural Polyisoprenes: Solve the Mystery of Natural Rubber Based on Structural Study Yasuyuki Tanaka · Rubber Chemistry and Technology Open access Jul 2001 288
46 Selective cytotoxic activities of two novel synthetic drugs on human breast carcinoma MCF-7 cells. Ramesh Babu Badisa, Selina Darling‐Reed, Patrick Joseph et al. · PubMed Open access Aug 2009 284
47 Prostate-Specific Antigen-Activated Thapsigargin Prodrug as Targeted Therapy for Prostate Cancer Samuel Ray Denmeade, Carsten M. Jakobsen, Stefan Janssen et al. · JNCI Journal of the National Cancer Institute Jul 2003 282
48 Guide to the Preparation, Use and Quality Assurance of Blood Components Kaaron Benson · Transfusion May 1999 279
49 Bufadienolides of plant and animal origin Pieter S. Steyn, Fanie R. van Heerden · Natural Product Reports 1998 274
50 Antimicrobial gallic acid from Caesalpinia mimosoides Lamk. Anchana Chanwitheesuk, Aphiwat Teerawutgulrag, Jeremy Kilburn et al. · Food Chemistry 28 Dec 2005 262

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.