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Most cited papers in Platelet Disorders and Treatments

What are the most cited papers in Platelet Disorders and Treatments?

The most cited paper in Platelet Disorders and Treatments is "Integrins: Versatility, modulation, and signaling in cell adhesion" (Richard O. Hynes, 1992), with 9,972 citations. Next come "International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)" (7,231) and "Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen" (5,034).

Showing 50 of 100 papers. Every paper with more than 1,043 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Integrins: Versatility, modulation, and signaling in cell adhesion Richard O. Hynes · Cell Apr 1992 9,972
2 International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) Spiros Miyakis, Michael D. Lockshin, Tatsuya Atsumi et al. · Journal of Thrombosis and Haemostasis Open access 13 Jan 2006 7,231
3 Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen David W. M. Leung, George Cachianes, Wun-Jing Kuang et al. · Science 8 Dec 1989 5,034
4 Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal G. V. R. Born · Nature Jun 1962 4,308
5 Hematological Problems in Pediatric Intensive Care Shoshana Revel‐Vilk, Peter N. Cox, Nancy Robitaille et al. · Pediatric and adolescent medicine Book chapter 28 Nov 2013 3,516
6 A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders Róbert Královics, Francesco Passamonti, Andreas S. Buser et al. · New England Journal of Medicine Open access 27 Apr 2005 3,491
7 Requirement of Vascular Integrin α v β 3 for Angiogenesis Peter C. Brooks, Richard A.F. Clark, David A. Cheresh · Science 22 Apr 1994 3,025
8 Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity Eugene C. Butcher · Cell Dec 1991 2,793
9 Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group Francesco Rodeghiero, Roberto Stasi, Terry Gernsheimer et al. · Blood Open access 12 Nov 2008 2,707
10 Use of a Monoclonal Antibody Directed against the Platelet Glycoprotein IIb/IIIa Receptor in High-Risk Coronary Angioplasty The EPIC Investigators · New England Journal of Medicine Open access 7 Apr 1994 2,610
11 Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 Mehrdad Matloubian, Charles G. Lo, Guy Cinamon et al. · Nature 2004 2,592
12 Extracellular DNA traps promote thrombosis Tobias A. Fuchs, Alexander G. Brill, Daniel Duerschmied et al. · Proceedings of the National Academy of Sciences Open access 23 Aug 2010 2,500
13 Genomic atlas of the human plasma proteome Benjamin B. Sun et al. · Nature Open access 29 May 2018 2,496
14 Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination Andreas Greinacher, Thomas Thiele, Theodore Earl Warkentin et al. · New England Journal of Medicine Open access 9 Apr 2021 2,300
15 International consensus report on the investigation and management of primary immune thrombocytopenia Drew Provan et al. · Blood Open access 21 Oct 2009 2,283
16 Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice Per Erik Lindahl, Bengt R. Johansson, Per Levéen et al. · Science Open access 11 Jul 1997 2,232
17 Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins Michael Brandeau Lawrence, Timothy A. Springer · Cell May 1991 2,162
18 A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis Srđan Verstovšek et al. · New England Journal of Medicine Open access 29 Feb 2012 2,106
19 CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells Volker Henn, Joseph R. Slupsky, Michael Gräfe et al. · Nature Feb 1998 2,088
20 WFH Guidelines for the Management of Hemophilia, 3rd edition Alok Srivastava, Elena Santagostino, Alison Dougall et al. · Haemophilia Open access Aug 2020 2,029
21 Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms Thorsten Klampfl et al. · New England Journal of Medicine Open access 10 Dec 2013 2,021
22 Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF) David M. Dohan Ehrenfest, Lars Rasmusson, Tomas O. Albrektsson · Trends in biotechnology Review Feb 2009 2,013
23 Disseminated Intravascular Coagulation Marcel M Levi, Hugo Ten Cate · New England Journal of Medicine 19 Aug 1999 2,005
24 Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning Samuel H. Davis, Thomas H. Aldrich, Pamela F. Jones et al. · Cell Open access Dec 1996 1,998
25 Thrombosis as an intravascular effector of innate immunity Bernd Engelmann, Steffen Maßberg · Nature reviews. Immunology ReviewOpen access 7 Dec 2012 1,969
26 Comparison of Plasma Exchange with Plasma Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura G. A. Rock, Kenneth H. Shumak, Noel A. Buskard et al. · New England Journal of Medicine Open access 8 Aug 1991 1,940
27 Guidelines for the management of hemophilia Alok Srivastava, A. Brewer, Evelien P. Mauser‐Bunschoten et al. · Haemophilia Open access 6 Jul 2012 1,938
28 Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence Cornelis Murre, Patrick Page-McCaw, Harald Vaessin et al. · Cell Aug 1989 1,895
29 The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia Cindy E. Neunert, Wendy Lim, Mark Andrew Crowther et al. · Blood 16 Feb 2011 1,869
30 Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation Oliver Borst, Britta Walker, Patrick Münzer et al. · Cellular Physiology and Biochemistry Open access 2013 1,863
31 VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site Mariano J. Elices, Laurelee Osborn, Yoshikazu Takada et al. · Cell Feb 1990 1,832
32 JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis Claire N. Harrison, Jean‐Jacques Kiladjian, Haifa Kathrin Al‐Ali et al. · New England Journal of Medicine Open access 29 Feb 2012 1,830
33 Nanoparticle biointerfacing by platelet membrane cloaking Che‐Ming Jack Hu et al. · Nature Open access 16 Sep 2015 1,814
34 Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis Giuseppe Lippi, Mario Plebani, Brandon Michael Henry · Clinica Chimica Acta ReviewOpen access 13 Mar 2020 1,800
35 Antibodies to von Willebrand Factor–Cleaving Protease in Acute Thrombotic Thrombocytopenic Purpura Han‐Mou Tsai, Eric Chun‐Yet Lian · New England Journal of Medicine Open access 26 Nov 1998 1,781
36 Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand Beate Heissig, Koichi Hattori, Sérgio Dias et al. · Cell Open access May 2002 1,753
37 Genetic Determinants of Response to Clopidogrel and Cardiovascular Events Tabassome Simon, Céline Verstuyft, Murielle Mary‐Krause et al. · New England Journal of Medicine Open access 22 Dec 2008 1,732
38 Platelets and the immune continuum John W. Semple, Joseph E. Italiano, John J Freedman · Nature reviews. Immunology Review 25 Mar 2011 1,710
39 The Nature and Significance of Platelet Products in Human Plasma Peter L. Wolf · British Journal of Haematology May 1967 1,702
40 von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome Miha Furlan, Rodolfo Robles, Miriam Galbusera et al. · New England Journal of Medicine Open access 26 Nov 1998 1,676
41 HIGH-DOSE INTRAVENOUS GAMMAGLOBULIN FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA IN CHILDHOOD Paul A. Imbach, Vincenzo D’Apuzzo, Andreas Hirt et al. · The Lancet Jun 1981 1,672
42 Evidence for Circulating Bone Marrow-Derived Endothelial Cells Qun Shi, Shahin Rafii, Moses Hong-De Wu et al. · Blood 15 Jul 1998 1,670
43 Platelets in atherothrombosis Zaverio M. Ruggeri · Nature Medicine Nov 2002 1,593
44 The Antiphospholipid Syndrome Jerrold S. Levine, David Ware Branch, Joyce Rauch · New England Journal of Medicine 7 Mar 2002 1,549
45 A Cell-based Model of Hemostasis Dougald M. Monroe, Maureane Hoffman · Thrombosis and Haemostasis 2001 1,542
46 Quantitative Determination of Serum Immunoglobulins in Antibody-Agar Plates John L. Fahey, Eugene M. McKelvey · The Journal of Immunology 1965 1,535
47 Heparan Sulfate Proteoglycans Sandrine Sarrazin, William C. Lamanna, Jeffrey D. Esko · Cold Spring Harbor Perspectives in Biology Open access 20 Jun 2011 1,534
48 Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination Nina Haagenrud Schultz, Ingvild Hausberg Sørvoll, Annika Elisabeth Michelsen et al. · New England Journal of Medicine Open access 9 Apr 2021 1,515
49 Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy Alan R. Shuldiner · JAMA Open access 25 Aug 2009 1,514
50 Autologous platelets as a source of proteins for healing and tissue regeneration Eduardo Anitua, Isabel Andı́a, Bruno Ardanza et al. · Thrombosis and Haemostasis 6 Nov 2003 1,499

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.