Most cited papers in Polyamine Metabolism and Applications
What are the most cited papers in Polyamine Metabolism and Applications?
The most cited paper in Polyamine Metabolism and Applications is "mTOR Signaling in Growth, Metabolism, and Disease" (Robert A. Saxton, David M. Sabatini, 2017), with 7,763 citations. Next come "Development by Self-Digestion" (3,681) and "Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?" (3,123).
Showing 50 of 100 papers. Every paper with more than 943 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | mTOR Signaling in Growth, Metabolism, and Disease Robert A. Saxton, David M. Sabatini · Cell | Mar 2017 | 7,763 |
| 2 | Development by Self-Digestion Beth Levine, Daniel J. Klionsky · Developmental Cell | Apr 2004 | 3,681 |
| 3 | Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Héctor Peinado, David Olmeda, Amparo Martínez Cano · Nature reviews. Cancer | 17 May 2007 | 3,123 |
| 4 | TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology | 12 Aug 2002 | 3,104 |
| 5 | Amino acids: metabolism, functions, and nutrition Guoyao Wu · Amino Acids | 19 Mar 2009 | 3,027 |
| 6 | mTOR at the nexus of nutrition, growth, ageing and disease Grace Y. Liu, David M. Sabatini · Nature Reviews Molecular Cell Biology | 14 Jan 2020 | 2,873 |
| 7 | The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1 Yasemin Sancak, Timothy R. Peterson, Yoav David Shaul et al. · Science | 22 May 2008 | 2,842 |
| 8 | Defining the Role of mTOR in Cancer David A. Guertin, David M. Sabatini · Cancer Cell | Jul 2007 | 2,838 |
| 9 | Arginine metabolism: nitric oxide and beyond Guoyao Wu, Sidney M. Morris · Biochemical Journal | 15 Nov 1998 | 2,830 |
| 10 | Molecular mechanisms of mTOR-mediated translational control Xiaoju Max Ma, John Blenis · Nature Reviews Molecular Cell Biology | 2 Apr 2009 | 2,595 |
| 11 | The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid Bruce N. Ames, Donald T. Dubin · Journal of Biological Chemistry | Mar 1960 | 2,583 |
| 12 | Molecular Anatomy of a Trafficking Organelle Shigeo Takamori et al. · Cell | Nov 2006 | 2,442 |
| 13 | Carbohydrate analysis by a phenol–sulfuric acid method in microplate format Tatsuya Masuko, Akio Minami, Norimasa Iwasaki et al. · Analytical Biochemistry | 29 Dec 2004 | 2,303 |
| 14 | Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method Irfan Rahman, Aruna Kode, Saibal K. Biswas · Nature Protocols | Dec 2006 | 2,277 |
| 15 | mTOR regulation of autophagy Chang Hwa Jung, Seung‐Hyun Ro, Jing Cao et al. · FEBS Letters | 18 Jan 2010 | 2,118 |
| 16 | Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling Shih-Min A. Huang et al. · Nature | 16 Sep 2009 | 2,105 |
| 17 | Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome Danny Liaw, Debbie J. Marsh, Jing Li et al. · Nature Genetics | May 1997 | 2,102 |
| 18 | Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy Nao Hosokawa, Taichi Hara, Takeshi Kaizuka et al. · Molecular Biology of the Cell | 11 Feb 2009 | 2,071 |
| 19 | New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway Lewis C. Cantley, Benjamin G. Neel · Proceedings of the National Academy of Sciences | 13 Apr 1999 | 2,041 |
| 20 | Mammalian autophagy: core molecular machinery and signaling regulation Zhifen Yang, Daniel J. Klionsky · Current Opinion in Cell Biology | 24 Dec 2009 | 1,979 |
| 21 | Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses Paul H. Yancey · Journal of Experimental Biology | 25 Jul 2005 | 1,878 |
| 22 | An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1 Carson C. Thoreen, Seong Anthony Woo Kang, Jae Won Chang et al. · Journal of Biological Chemistry | 16 Jan 2009 | 1,844 |
| 23 | Role of Pseudomonas putida Indoleacetic Acid in Development of the Host Plant Root System Cheryl L. Patten, Bernard R. Glick · Applied and Environmental Microbiology | Aug 2002 | 1,814 |
| 24 | Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy Paul L. Nicklin, Philip J. Bergman, Bailin Zhang et al. · Cell | Feb 2009 | 1,810 |
| 25 | Induction of autophagy by spermidine promotes longevity Tobias Eisenberg et al. · Nature Cell Biology | 4 Oct 2009 | 1,699 |
| 26 | Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose David A. Johnson, James W. Gautsch, J. Richard Sportsman et al. · Gene Analysis Techniques | 1984 | 1,686 |
| 27 | Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role Kris Vleminckx, Luc C. Vakaet, M. Mareel et al. · Cell | Jul 1991 | 1,677 |
| 28 | Acrylamide from Maillard reaction products Richard H. Stadler, Imre Blank, Natalia Varga et al. · Nature | Oct 2002 | 1,675 |
| 29 | Polyamine metabolism and function Anthony E. Pegg, Peter P. McCann · American Journal of Physiology-Cell Physiology | Nov 1982 | 1,664 |
| 30 | Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus Michael Derek Waterfield, Geoffrey T. Scrace, Nigel Whittle et al. · Nature | Jul 1983 | 1,638 |
| 31 | Recent advances in the biochemistry of polyamines in eukaryotes Anthony E. Pegg · Biochemical Journal | Mar 1986 | 1,586 |
| 32 | ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy Ian G. Ganley, Du Lam, Junru Wang et al. · Journal of Biological Chemistry | 3 Mar 2009 | 1,574 |
| 33 | Identification of the Tuberous Sclerosis Complex-2 Tumor Suppressor Gene Product Tuberin as a Target of the Phosphoinositide 3-Kinase/Akt Pathway Brendan D. Manning, Andrew R. Tee, M. Nicole Logsdon et al. · Molecular Cell | Jul 2002 | 1,568 |
| 34 | Growing roles for the mTOR pathway Dos D. Sarbassov, Siraj Mahamed Ali, David M. Sabatini · Current Opinion in Cell Biology | 14 Oct 2005 | 1,565 |
| 35 | Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals Peter Setlow · Journal of Applied Microbiology | 5 Apr 2006 | 1,557 |
| 36 | Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Chantale T. Guy, Robert D. Cardiff, William J. Muller · Molecular and Cellular Biology | Mar 1992 | 1,554 |
| 37 | METHOD FOR THE DETERMINATION OF HEXOSAMINES IN TISSUES Norman F. Boas · Journal of Biological Chemistry | Oct 1953 | 1,533 |
| 38 | Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. Anthony E. Pegg · PubMed | 15 Feb 1988 | 1,526 |
| 39 | Biogenic amines: their importance in foods M.H.Silla Santos · International Journal of Food Microbiology | Apr 1996 | 1,521 |
| 40 | p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription Ashish Jain, Trond Lamark, Eva Sjøttem et al. · Journal of Biological Chemistry | 7 May 2010 | 1,511 |
| 41 | Microbiological spoilage of fish and fish products Lone Gram, Hans Henrik Huss · International Journal of Food Microbiology | Nov 1996 | 1,484 |
| 42 | Carbonic anhydrase inhibitors Claudiu Trandafir Supuran, Andrea Scozzafava, Angela Casini · Medicinal Research Reviews | 13 Dec 2002 | 1,450 |
| 43 | Nucleic acid-based approaches to investigate microbial-related cheese quality defects Daniel J. O’Sullivan, Linda M. Giblin, Paul L.H. McSweeney et al. · Frontiers in Microbiology | 2013 | 1,420 |
| 44 | A Selected Core Microbiome Drives the Early Stages of Three Popular Italian Cheese Manufactures Francesca De Filippis, Antonietta La Storia, Giuseppina Stellato et al. · PLoS ONE | 24 Feb 2014 | 1,414 |
| 45 | Ethylene biosynthesis: Identification of 1-aminocyclopropane-1-carboxylic acid as an intermediate in the conversion of methionine to ethylene Douglas O. Adams, Shang Fa Yang · Proceedings of the National Academy of Sciences | 1979 | 1,392 |
| 46 | Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism Kenta Hara, Kazuyoshi Yonezawa, Qing-Ping Weng et al. · Journal of Biological Chemistry | Jun 1998 | 1,382 |
| 47 | New Methods for the Synthesis of Glycosides and Oligosaccharides—Are There Alternatives to the Koenigs‐Knorr Method? [New Synthetic Methods (56)] Richard R. Schmidt · Angewandte Chemie International Edition in English | Mar 1986 | 1,381 |
| 48 | Polyamines in rapid growth and cancer J Jänne · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | Apr 1978 | 1,349 |
| 49 | p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling Andrei V. Budanov, Michael Karin · Cell | Aug 2008 | 1,340 |
| 50 | Sestrin2 is a leucine sensor for the mTORC1 pathway Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton et al. · Science | 8 Oct 2015 | 1,322 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.