Most cited papers in Renal and related cancers
What are the most cited papers in Renal and related cancers?
The most cited paper in Renal and related cancers is "Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors" (Kazutoshi Takahashi, Shinya Yamanaka, 2006), with 26,957 citations. Next come "Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (10,385) and "Specific Association of Human Telomerase Activity with Immortal Cells and Cancer" (7,190).
Showing 50 of 99 papers. Every paper with more than 1,262 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Kazutoshi Takahashi, Shinya Yamanaka · Cell | Aug 2006 | 26,957 |
| 2 | Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science | 20 Nov 2007 | 10,385 |
| 3 | Specific Association of Human Telomerase Activity with Immortal Cells and Cancer Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science | 23 Dec 1994 | 7,190 |
| 4 | Analysis of nanoparticle delivery to tumours Stefan Wilhelm, Anthony J. Tavares, Qin Dai et al. · Nature Reviews Materials | 26 Apr 2016 | 5,120 |
| 5 | Viable offspring derived from fetal and adult mammalian cells I. Wilmut, Angelika Schnieke, J. McWhir et al. · Nature | Feb 1997 | 4,968 |
| 6 | Generation of germline-competent induced pluripotent stem cells Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka · Nature | 6 Jun 2007 | 4,268 |
| 7 | Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia Sharon E. Maynard, Jiang-Yong Min, Jaime Rafael Merchan et al. · Journal of Clinical Investigation | Mar 2003 | 4,020 |
| 8 | TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell | Nov 2003 | 3,949 |
| 9 | Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells Hitoshi Niwa, Jun‐ichi Miyazaki, Austin G Smith · Nature Genetics | Apr 2000 | 3,640 |
| 10 | Comprehensive molecular characterization of clear cell renal cell carcinoma Chad J. Creighton et al. · Nature | 23 Jun 2013 | 3,603 |
| 11 | TGF-β: the master regulator of fibrosis Xiao‐Ming Meng, David J. Nikolic‐Paterson, Hui Y. Lan · Nature Reviews Nephrology | 25 Apr 2016 | 3,595 |
| 12 | Organoid Models and Applications in Biomedical Research Christodoulos Xinaris, Valerio Brizi, Giuseppe Remuzzi · The Nephron journals/Nephron journals | 2015 | 3,519 |
| 13 | Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 Jennifer Nichols, Branko Zevnik, Konstantinos Anastassiadis et al. · Cell | Oct 1998 | 3,421 |
| 14 | Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells Ian Chambers, Douglas Colby, Morag Robertson et al. · Cell | May 2003 | 3,286 |
| 15 | Modeling Development and Disease with Organoids Hans C. Clevers · Cell | Jun 2016 | 3,282 |
| 16 | Glypican-1 identifies cancer exosomes and detects early pancreatic cancer Sónia A. Melo, Linda B. Luecke, Christoph Kahlert et al. · Nature | 24 Jun 2015 | 2,923 |
| 17 | Reprogramming of human somatic cells to pluripotency with defined factors In‐Hyun Park, Rui Zhao, Jason A. West et al. · Nature | 23 Dec 2007 | 2,890 |
| 18 | Renal cell carcinoma James J.-D. Hsieh, Mark P. Purdue, Sabina Signoretti et al. · Nature Reviews Disease Primers | 9 Mar 2017 | 2,857 |
| 19 | Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe et al. · Nature Biotechnology | 30 Nov 2007 | 2,802 |
| 20 | The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells Eduard Batlle, Elena Lanchares Sancho, Clara Francı́ et al. · Nature Cell Biology | 13 Jan 2000 | 2,690 |
| 21 | In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state Marius Wernig, Alexander Meissner, Ruth K. Foreman et al. · Nature | 6 Jun 2007 | 2,682 |
| 22 | The R.E.N.A.L. Nephrometry Score: A Comprehensive Standardized System for Quantitating Renal Tumor Size, Location and Depth Alexander Kutikov, Robert G. Uzzo · The Journal of Urology | 18 Jul 2009 | 2,426 |
| 23 | A molecular mechanism for the effect of lithium on development. Peter S. Klein, Douglas A. Melton · Proceedings of the National Academy of Sciences | 6 Aug 1996 | 2,309 |
| 24 | Epithelial-mesenchymal transition and its implications for fibrosis Raghu K. Kalluri, Eric G. Neilson · Journal of Clinical Investigation | 15 Dec 2003 | 2,297 |
| 25 | Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei Teruhiko Wakayama, Anthony C.F. Perry, Maurizio Zuccotti et al. · Nature | Jul 1998 | 2,270 |
| 26 | Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Bernard J. Escudier, Camillo Porta, Manuela Schmidinger et al. · Annals of Oncology | Sep 2014 | 2,263 |
| 27 | Renal-Cell Carcinoma Robert John Motzer, Neil Harrison Bander, David M. Nanus · New England Journal of Medicine | 19 Sep 1996 | 2,251 |
| 28 | Human organoids: model systems for human biology and medicine Jihoon Kim, Bon‐Kyoung Koo, Juergen A. Knoblich · Nature Reviews Molecular Cell Biology | 7 Jul 2020 | 2,211 |
| 29 | DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Sabine Jahr, Hannes Hentze, Susanne Englisch et al. · PubMed | 15 Feb 2001 | 2,211 |
| 30 | New cell lines from mouse epiblast share defining features with human embryonic stem cells Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook et al. · Nature | 27 Jun 2007 | 2,195 |
| 31 | BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3 Qi-Long Ying, Jennifer Nichols, Ian Chambers et al. · Cell | Oct 2003 | 2,129 |
| 32 | Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics | 6 Jan 2003 | 2,064 |
| 33 | The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Em et al. · Human Reproduction | 18 Apr 2011 | 2,058 |
| 34 | WT-1 is required for early kidney development Jordan A. Kreidberg, Hannu V. Sariola, Janet M. Loring et al. · Cell | Aug 1993 | 2,019 |
| 35 | Targeting cancer stem cell pathways for cancer therapy Liqun Yang, Pengfei Shi, Gaichao Zhao et al. · Signal Transduction and Targeted Therapy | 6 Feb 2020 | 1,971 |
| 36 | The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium Thomas Doetschman, Harald R. Eistetter, Margot Katz et al. · Development | Jun 1985 | 1,964 |
| 37 | Naive and Primed Pluripotent States Jennifer Nichols, Austin G Smith · Cell stem cell | Jun 2009 | 1,936 |
| 38 | The primary cilium: a signalling centre during vertebrate development Sarah C. Goetz, Kathryn V. Anderson · Nature Reviews Genetics | 16 Apr 2010 | 1,905 |
| 39 | Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus Katherine M. Call, Tom M. Glaser, Caryn Y. Ito et al. · Cell | Feb 1990 | 1,895 |
| 40 | Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome Marjo Kestilä, Ulla Lenkkeri, Minna Männikkö et al. · Molecular Cell | Mar 1998 | 1,890 |
| 41 | Generation of cerebral organoids from human pluripotent stem cells Madeline A. Lancaster, Juergen A. Knoblich · Nature Protocols | 4 Sep 2014 | 1,889 |
| 42 | Guideline for Management of the Clinical T1 Renal Mass Steven C. Campbell, Andrew C. Novick, Arie S. Belldegrun et al. · The Journal of Urology | 27 Aug 2009 | 1,844 |
| 43 | Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature | Oct 1997 | 1,817 |
| 44 | Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Glenn E. Winnier, M Blessing, Patricia Ann Labosky et al. · Genes & Development | Sep 1995 | 1,807 |
| 45 | Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas Gang Wu et al. · Nature Genetics | 29 Jan 2012 | 1,783 |
| 46 | AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells Amy H. Yin, Sheri J. Miraglia, Esmail D. Zanjani et al. · Blood | 15 Dec 1997 | 1,770 |
| 47 | Mutations of the VHL tumour suppressor gene in renal carcinoma James R. Gnarra et al. · Nature Genetics | May 1994 | 1,752 |
| 48 | Genes and molecular pathways underpinning ciliopathies Jeremy F. Reiter, Michel R. Leroux · Nature Reviews Molecular Cell Biology | 12 Jul 2017 | 1,751 |
| 49 | Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution Nimet Maherali, Rupa Sridharan, Wei Xie et al. · Cell stem cell | Jun 2007 | 1,739 |
| 50 | Induced Pluripotent Stem Cells Generated Without Viral Integration Matthias Stadtfeld, Masaki Nagaya, Jochen Sven Utikal et al. · Science | 25 Sep 2008 | 1,675 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.