Science Explorer Back to mapMap

Most cited papers in Renal and related cancers

What are the most cited papers in Renal and related cancers?

The most cited paper in Renal and related cancers is "Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors" (Kazutoshi Takahashi, Shinya Yamanaka, 2006), with 26,957 citations. Next come "Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells" (10,385) and "Specific Association of Human Telomerase Activity with Immortal Cells and Cancer" (7,190).

Showing 50 of 99 papers. Every paper with more than 1,262 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Kazutoshi Takahashi, Shinya Yamanaka · Cell Open access Aug 2006 26,957
2 Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science 20 Nov 2007 10,385
3 Specific Association of Human Telomerase Activity with Immortal Cells and Cancer Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science 23 Dec 1994 7,190
4 Analysis of nanoparticle delivery to tumours Stefan Wilhelm, Anthony J. Tavares, Qin Dai et al. · Nature Reviews Materials ReviewOpen access 26 Apr 2016 5,120
5 Viable offspring derived from fetal and adult mammalian cells I. Wilmut, Angelika Schnieke, J. McWhir et al. · Nature Feb 1997 4,968
6 Generation of germline-competent induced pluripotent stem cells Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka · Nature 6 Jun 2007 4,268
7 Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia Sharon E. Maynard, Jiang-Yong Min, Jaime Rafael Merchan et al. · Journal of Clinical Investigation Open access Mar 2003 4,020
8 TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell Open access Nov 2003 3,949
9 Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells Hitoshi Niwa, Jun‐ichi Miyazaki, Austin G Smith · Nature Genetics Apr 2000 3,640
10 Comprehensive molecular characterization of clear cell renal cell carcinoma Chad J. Creighton et al. · Nature Open access292 authors 23 Jun 2013 3,603
11 TGF-β: the master regulator of fibrosis Xiao‐Ming Meng, David J. Nikolic‐Paterson, Hui Y. Lan · Nature Reviews Nephrology Review 25 Apr 2016 3,595
12 Organoid Models and Applications in Biomedical Research Christodoulos Xinaris, Valerio Brizi, Giuseppe Remuzzi · ˜The œNephron journals/Nephron journals Open access 2015 3,519
13 Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 Jennifer Nichols, Branko Zevnik, Konstantinos Anastassiadis et al. · Cell Open access Oct 1998 3,421
14 Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells Ian Chambers, Douglas Colby, Morag Robertson et al. · Cell Open access May 2003 3,286
15 Modeling Development and Disease with Organoids Hans C. Clevers · Cell Open access Jun 2016 3,282
16 Glypican-1 identifies cancer exosomes and detects early pancreatic cancer Sónia A. Melo, Linda B. Luecke, Christoph Kahlert et al. · Nature Open access 24 Jun 2015 2,923
17 Reprogramming of human somatic cells to pluripotency with defined factors In‐Hyun Park, Rui Zhao, Jason A. West et al. · Nature 23 Dec 2007 2,890
18 Renal cell carcinoma James J.-D. Hsieh, Mark P. Purdue, Sabina Signoretti et al. · Nature Reviews Disease Primers ReviewOpen access 9 Mar 2017 2,857
19 Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe et al. · Nature Biotechnology 30 Nov 2007 2,802
20 The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells Eduard Batlle, Elena Lanchares Sancho, Clara Francı́ et al. · Nature Cell Biology 13 Jan 2000 2,690
21 In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state Marius Wernig, Alexander Meissner, Ruth K. Foreman et al. · Nature 6 Jun 2007 2,682
22 The R.E.N.A.L. Nephrometry Score: A Comprehensive Standardized System for Quantitating Renal Tumor Size, Location and Depth Alexander Kutikov, Robert G. Uzzo · The Journal of Urology 18 Jul 2009 2,426
23 A molecular mechanism for the effect of lithium on development. Peter S. Klein, Douglas A. Melton · Proceedings of the National Academy of Sciences Open access 6 Aug 1996 2,309
24 Epithelial-mesenchymal transition and its implications for fibrosis Raghu K. Kalluri, Eric G. Neilson · Journal of Clinical Investigation Open access 15 Dec 2003 2,297
25 Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei Teruhiko Wakayama, Anthony C.F. Perry, Maurizio Zuccotti et al. · Nature Jul 1998 2,270
26 Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Bernard J. Escudier, Camillo Porta, Manuela Schmidinger et al. · Annals of Oncology Open access Sep 2014 2,263
27 Renal-Cell Carcinoma Robert John Motzer, Neil Harrison Bander, David M. Nanus · New England Journal of Medicine 19 Sep 1996 2,251
28 Human organoids: model systems for human biology and medicine Jihoon Kim, Bon‐Kyoung Koo, Juergen A. Knoblich · Nature Reviews Molecular Cell Biology ReviewOpen access 7 Jul 2020 2,211
29 DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Sabine Jahr, Hannes Hentze, Susanne Englisch et al. · PubMed 15 Feb 2001 2,211
30 New cell lines from mouse epiblast share defining features with human embryonic stem cells Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook et al. · Nature 27 Jun 2007 2,195
31 BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3 Qi-Long Ying, Jennifer Nichols, Ian Chambers et al. · Cell Open access Oct 2003 2,129
32 Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells Surya M. Nauli, Francis J. Alenghat, Ying Luo et al. · Nature Genetics 6 Jan 2003 2,064
33 The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Em et al. · Human Reproduction Open access 18 Apr 2011 2,058
34 WT-1 is required for early kidney development Jordan A. Kreidberg, Hannu V. Sariola, Janet M. Loring et al. · Cell Aug 1993 2,019
35 Targeting cancer stem cell pathways for cancer therapy Liqun Yang, Pengfei Shi, Gaichao Zhao et al. · Signal Transduction and Targeted Therapy Open access 6 Feb 2020 1,971
36 The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium Thomas Doetschman, Harald R. Eistetter, Margot Katz et al. · Development Jun 1985 1,964
37 Naive and Primed Pluripotent States Jennifer Nichols, Austin G Smith · Cell stem cell Open access Jun 2009 1,936
38 The primary cilium: a signalling centre during vertebrate development Sarah C. Goetz, Kathryn V. Anderson · Nature Reviews Genetics ReviewOpen access 16 Apr 2010 1,905
39 Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus Katherine M. Call, Tom M. Glaser, Caryn Y. Ito et al. · Cell Feb 1990 1,895
40 Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome Marjo Kestilä, Ulla Lenkkeri, Minna Männikkö et al. · Molecular Cell Open access Mar 1998 1,890
41 Generation of cerebral organoids from human pluripotent stem cells Madeline A. Lancaster, Juergen A. Knoblich · Nature Protocols Open access 4 Sep 2014 1,889
42 Guideline for Management of the Clinical T1 Renal Mass Steven C. Campbell, Andrew C. Novick, Arie S. Belldegrun et al. · The Journal of Urology 27 Aug 2009 1,844
43 Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling Atsuhito Nakao, Mozhgan Afrakhte, Anita Morn et al. · Nature Oct 1997 1,817
44 Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Glenn E. Winnier, M Blessing, Patricia Ann Labosky et al. · Genes & Development Open access Sep 1995 1,807
45 Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas Gang Wu et al. · Nature Genetics Open access 29 Jan 2012 1,783
46 AC133, a Novel Marker for Human Hematopoietic Stem and Progenitor Cells Amy H. Yin, Sheri J. Miraglia, Esmail D. Zanjani et al. · Blood Open access 15 Dec 1997 1,770
47 Mutations of the VHL tumour suppressor gene in renal carcinoma James R. Gnarra et al. · Nature Genetics May 1994 1,752
48 Genes and molecular pathways underpinning ciliopathies Jeremy F. Reiter, Michel R. Leroux · Nature Reviews Molecular Cell Biology ReviewOpen access 12 Jul 2017 1,751
49 Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution Nimet Maherali, Rupa Sridharan, Wei Xie et al. · Cell stem cell Open access Jun 2007 1,739
50 Induced Pluripotent Stem Cells Generated Without Viral Integration Matthias Stadtfeld, Masaki Nagaya, Jochen Sven Utikal et al. · Science Open access 25 Sep 2008 1,675

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.