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Most cited papers in Saffron Plant Research Studies

What are the most cited papers in Saffron Plant Research Studies?

The most cited paper in Saffron Plant Research Studies is "Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms" (Kumiko Ishige, David A. Schubert, Yutaka Sagara, 2001), with 843 citations. Next come "Carotenoids: biochemistry, pharmacology and treatment" (793) and "Genipin-crosslinked chitosan hydrogels as biomedical and pharmaceutical aids" (725).

Showing 50 of 100 papers. Every paper with more than 236 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms Kumiko Ishige, David A. Schubert, Yutaka Sagara · Free Radical Biology and Medicine Feb 2001 843
2 Carotenoids: biochemistry, pharmacology and treatment Alireza Milani, Marzieh Basirnejad, Sepideh Shahbazi et al. · British Journal of Pharmacology Open access 17 Sep 2016 793
3 Genipin-crosslinked chitosan hydrogels as biomedical and pharmaceutical aids Riccardo A.A. Müzzarelli · Carbohydrate Polymers 30 Jan 2009 725
4 C-Phycocyanin: A Biliprotein with Antioxidant, Anti-Inflammatory and Neuroprotective Effects Ch. Romay, Ricardo González, Nuris Ledón et al. · Current Protein and Peptide Science Jun 2003 718
5 Effects of Long-Term Selenium Supplementation on the Incidence of Type 2 Diabetes Saverio Stranges, James R. Marshall, Raj Natarajan et al. · Annals of Internal Medicine 21 Aug 2007 715
6 Advances in ultrasound assisted extraction of bioactive compounds from cash crops – A review Chaoting Wen, Jixian Zhang, Haihui Zhang et al. · Ultrasonics Sonochemistry Open access 18 Jul 2018 714
7 Antimicrobial and Chemopreventive Properties of Herbs and Spices Pengxiang Lai, Jiben Roy · Current Medicinal Chemistry Jun 2004 615
8 Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice Hossein Hosseinzadeh, Hani M Younesi · BMC Pharmacology Open access 15 Mar 2002 606
9 A review of the worldwide prevalence of vitiligo in children/adolescents and adults Christian Krüger, Karin Uta Schallreuter · International Journal of Dermatology 27 Mar 2012 581
10 Studies on the antioxidant activity of Indian Laburnum (Cassia fistula L.): a preliminary assessment of crude extracts from stem bark, leaves, flowers and fruit pulp Perumal Siddhuraju · Food Chemistry Oct 2002 526
11 Fisetin: A Dietary Antioxidant for Health Promotion Naghma Khan, Deeba N. Syed, Nihal Ahmad et al. · Antioxidants and Redox Signaling Open access 2 Nov 2012 516
12 An Update Review of Saffron and its Active Constituents José Luis Rı́os, M. Carmen Recio, Rosa María Giner et al. · Phytotherapy Research May 1996 500
13 C-Phycocyanin: A Potent Peroxyl Radical Scavenger in Vivo and in Vitro Vadiraja B. Bhat, K. Madhava Madyastha · Biochemical and Biophysical Research Communications Aug 2000 479
14 Curcumin, the Golden Spice From Indian Saffron, Is a Chemosensitizer and Radiosensitizer for Tumors and Chemoprotector and Radioprotector for Normal Organs Ajay Goel, Bharat Bhushan Aggarwal · Nutrition and Cancer 23 Sep 2010 466
15 A review on plant-based rutin extraction methods and its pharmacological activities Lee Suan Chua · Journal of Ethnopharmacology 30 Oct 2013 465
16 Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials Fikrat I. Abdullaev, Jesús Javier Espinosa-Aguirre · Cancer Detection and Prevention 2004 434
17 Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells Kyong Nyon Nam, Young-Min Park, Hoon-Ji Jung et al. · European Journal of Pharmacology 19 Sep 2010 432
18 Radical scavenging activity ofCrocus sativus L. extract and its bioactive constituents Andreana N. Assimopoulou, Z Sinakos, Vassilios P. Papageorgiou · Phytotherapy Research 2005 429
19 The genus Scutellaria an ethnopharmacological and phytochemical review Xiaofei Shang, Xirui He, Xiaoying He et al. · Journal of Ethnopharmacology Open access 12 Jan 2010 412
20 Anti-inflammatory evaluation of gardenia extract, geniposide and genipin Hye-Jin Koo, Kyung-Hwa Lim, Hyun‐Joo Jung et al. · Journal of Ethnopharmacology 20 Sep 2005 404
21 Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin J. Renugadevi, Selvaraj Milton Prabu · Experimental and Toxicologic Pathology 6 May 2009 393
22 Distinctive Antioxidant and Antiinflammatory Effects of Flavonols Lisu Wang, Yi-Chen Tu, Tzi-Wei Lian et al. · Journal of Agricultural and Food Chemistry 22 Nov 2006 391
23 Crocin, safranal and picrocrocin from saffron (Crocus sativus L.) inhibit the growth of human cancer cells in vitro Julio Escribano, Gonzalo L. Alonso, Miguel Coca‐Prados et al. · Cancer Letters Open access Feb 1996 386
24 Herbal Medicine as Inducers of Apoptosis in Cancer Treatment Elham Safarzadeh, Siamak Sandoghchian Shotorbani, Behzad Baradaran · PubMed Open access 2014 383
25 Bioactivity assessment and toxicity of crocin: A comprehensive review Seyedeh Hoda Alavizadeh, Hossein Hosseinzadeh · Food and Chemical Toxicology 22 Nov 2013 383
26 Chemical and biological properties of the world's most expensive spice: Saffron John P. Melnyk, Sunan Wang, Massimo F. Marcone · Food Research International 4 Aug 2010 377
27 Quercetin Induces Apoptosis via Caspase Activation, Regulation of Bcl-2, and Inhibition of PI-3-Kinase/Akt and ERK Pathways in a Human Hepatoma Cell Line (HepG2) Ana Beleén Granado-Serrano, Mariía Angeles Martiín, Laura Bravo et al. · Journal of Nutrition Open access Nov 2006 377
28 Chemical Composition of the Fixed and Volatile Oils of Nigella sativa L. from Iran Bahman Nickavar, Faraz Mojab, Katayoun Javidnia et al. · Zeitschrift für Naturforschung C Open access Oct 2003 361
29 Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type Hayate Javed, Mohammad Moshahid Khan, Ajmal Ahmad et al. · Neuroscience 6 Mar 2012 356
30 Low cost biosorbent “banana peel” for the removal of phenolic compounds from olive mill wastewater: Kinetic and equilibrium studies Mounia Achak, Abdellatif Hafidi, Naaila Ouazzani et al. · Journal of Hazardous Materials 22 Nov 2008 354
31 Determination of saffron (Crocus sativus L.) components in crude plant extract using high-performance liquid chromatography-UV-visible photodiode-array detection-mass spectrometry Petros A. Tarantilis, G. Tsoupras, Moschos G. Polissiou · Journal of Chromatography A May 1995 350
32 Moroccan Medicinal plants as inhibitors against SARS-CoV-2 main protease: Computational investigations Ilham Aanouz, Assia Belhassan, K. El-Khatabi et al. · Journal of Biomolecular Structure and Dynamics Open access 20 Apr 2020 348
33 Inhibitory Activity on Amyloid-β Aggregation and Antioxidant Properties ofCrocus sativusStigmas Extract and Its Crocin Constituents Magdalini A. Papandreou, Charalabos D. Kanakis, Moschos G. Polissiou et al. · Journal of Agricultural and Food Chemistry 20 Oct 2006 342
34 Medicinal plants and food medicines in the folk traditions of the upper Lucca Province, Italy Andréa Pieroni · Journal of Ethnopharmacology Jul 2000 341
35 Drug release from chitosan–alginate complex beads reinforced by a naturally occurring cross-linking agent Fwu‐Long Mi, Hsing‐Wen Sung, Shin-Shing Shyu · Carbohydrate Polymers Apr 2002 331
36 SAFFRON—RENEWED INTEREST IN AN ANCIENT SPICE Peter Winterhalter, Markus Straubinger · Food Reviews International 2 Sep 2000 328
37 Crocus sativus L.: A comprehensive review Rajani Srivastava, Hiwa M. Ahmed, RK Dixit et al. · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review Open access 2010 325
38 Cadmium Is a Novel and Independent Risk Factor for Early Atherosclerosis Mechanisms and In Vivo Relevance Barbara Meßner, Michael Knoflach, Andreas Seubert et al. · Arteriosclerosis Thrombosis and Vascular Biology Open access 26 Jun 2009 323
39 Antiinflammatory effects of genipin, an active principle of gardenia Hye-Jin Koo, Yun Seon Song, Hee-Jeong Kim et al. · European Journal of Pharmacology 29 Jun 2004 315
40 Grape Pomace Valorization: A Systematic Review and Meta-Analysis Bojan Antonić, Simona Jančíková, Đani Đorđević et al. · Foods ReviewOpen access 7 Nov 2020 314
41 Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial Ahmad-Ali Noorbala, Shahin Akhondzadeh, Najaf Tahmacebi‐Pour et al. · Journal of Ethnopharmacology 7 Jan 2005 311
42 Oxidative Remodeling of Chromoplast Carotenoids Florence Bouvier, Claude Suire, Jérôme Mutterer et al. · The Plant Cell Open access 19 Dec 2002 311
43 Green synthesis of silver nanoparticles using aqueous extract of saffron (Crocus sativus L.) wastages and its antibacterial activity against six bacteria Ghodsieh Bagherzade, Maryam Manzari Tavakoli, Mohammad Hasan Namaei · Asian Pacific Journal of Tropical Biomedicine Open access 16 Dec 2016 307
44 Feasibility study of a natural crosslinking reagent for biological tissue fixation Hsing‐Wen Sung, Rong Huang, Lynn L. H. Huang et al. · Journal of Biomedical Materials Research 15 Dec 1998 306
45 Application of maltodextrin and gum Arabic in microencapsulation of saffron petal's anthocyanins and evaluating their storage stability and color K. Mahdavee Khazaei, Seid Mahdi Jafari, Mohammad Ghorbani et al. · Carbohydrate Polymers 22 Jan 2014 305
46 Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review Zahra Gholamnezhad, Shahrzad Havakhah, Mohammad Hossein Boskabady · Journal of Ethnopharmacology 28 Jun 2016 304
47 Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial [ISRCTN45683816] Shahin Akhondzadeh, Hasan Fallah-Pour, Khosro Afkham et al. · BMC Complementary and Alternative Medicine Open access 2 Sep 2004 304
48 THE ACTION OF LIGHT ON RHODOPSIN Ruth Hubbard, Allen Kropf · Proceedings of the National Academy of Sciences Open access Feb 1958 300
49 Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis Sarah Frusciante, Gianfranco Diretto, Mark Bruno et al. · Proceedings of the National Academy of Sciences Open access 5 Aug 2014 300
50 Therapeutic benefits of rutin and its nanoformulations Ramin Negahdari, Sepideh Bohlouli, Simin Sharifi et al. · Phytotherapy Research 15 Oct 2020 298

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.