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Topic · SARS-CoV-2 and COVID-19 Research

Most cited papers in SARS-CoV-2 and COVID-19 Research

SARS-CoV-2 and COVID-19 Research

What are the most cited papers in SARS-CoV-2 and COVID-19 Research?

The most cited paper in SARS-CoV-2 and COVID-19 Research is "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China" (Chaolin Huang et al., 2020), with 52,028 citations. Next come "Clinical Characteristics of Coronavirus Disease 2019 in China" (31,256) and "A Novel Coronavirus from Patients with Pneumonia in China, 2019" (30,499).

Showing 50 of 100 papers. Every paper with more than 2,821 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Chaolin Huang et al. · The Lancet Open access 24 Jan 2020 52,028
2 Clinical Characteristics of Coronavirus Disease 2019 in China Wei‐jie Guan et al. · New England Journal of Medicine Open access 28 Feb 2020 31,256
3 A Novel Coronavirus from Patients with Pneumonia in China, 2019 Na Zhu, Dingyu Zhang, Wenling Wang et al. · New England Journal of Medicine Open access 24 Jan 2020 30,499
4 A pneumonia outbreak associated with a new coronavirus of probable bat origin Peng Zhou et al. · Nature Open access 3 Feb 2020 23,429
5 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Nanshan Chen, Min Zhou, Xuan Dong et al. · The Lancet Open access 30 Jan 2020 22,766
6 SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Markus Hoffmann, Hannah Kleine‐Weber, Simon Schroeder et al. · Cell Open access 8 Mar 2020 21,493
7 Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China Dawei Wang, Bo Hu, Chang Hu et al. · JAMA Open access 7 Feb 2020 21,261
8 La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19 Martínez González, Marina · DSPACE System - Metalibrary (University of the Coast) Open access 2020 19,306
9 Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia Qun Li et al. · New England Journal of Medicine Open access 29 Jan 2020 18,005
10 Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine Fernando P. Polack et al. · New England Journal of Medicine Open access 10 Dec 2020 15,741
11 A new coronavirus associated with human respiratory disease in China Fan Wu et al. · Nature Open access 3 Feb 2020 12,967
12 Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Roujian Lu et al. · The Lancet Open access 30 Jan 2020 12,621
13 Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine Lindsey R. Baden et al. · New England Journal of Medicine Open access 30 Dec 2020 10,910
14 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett et al. · Science Open access 19 Feb 2020 9,833
15 A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Jasper Fuk‐Woo Chan et al. · The Lancet Open access 24 Jan 2020 9,628
16 Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein Alexandra C. Walls, Young‐Jun Park, M. Alejandra Tortorici et al. · Cell Open access 9 Mar 2020 9,155
17 Pathological findings of COVID-19 associated with acute respiratory distress syndrome Zhe Xu, Lei Shi, Yijin Wang et al. · The Lancet Respiratory Medicine Open access 18 Feb 2020 8,909
18 Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Victor M. Corman et al. · Eurosurveillance Open access 23 Jan 2020 8,218
19 A novel coronavirus outbreak of global health concern Chen Wang, Peter Horby, Frederick G. Hayden et al. · The Lancet Open access 24 Jan 2020 8,144
20 The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 Alexander E. Gorbalenya, Susan C. Baker, Ralph Steven Baric et al. · Nature Microbiology Open access 2 Mar 2020 7,774
21 Remdesivir for the Treatment of Covid-19 — Final Report John H. Beigel et al. · New England Journal of Medicine Open access 22 May 2020 7,759
22 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Manli Wang, Ruiyuan Cao, Leike Zhang et al. · Cell Research Open access 4 Feb 2020 7,401
23 Virological assessment of hospitalized patients with COVID-2019 Roman Wölfel, Victor M. Corman, Wolfgang Guggemos et al. · Nature Open access Apr 2020 7,240
24 Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Jun Lan, Jiwan Ge, Jinfang Yu et al. · Nature Open access 30 Mar 2020 6,769
25 First Case of 2019 Novel Coronavirus in the United States Michelle L. Holshue et al. · New England Journal of Medicine Open access 31 Jan 2020 6,413
26 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges Chih‐Cheng Lai, Tzu-Ping Shih, Wen‐Chien Ko et al. · International Journal of Antimicrobial Agents Open access 17 Feb 2020 6,402
27 World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19) Catrin Sohrabi, Zaid Alsafi, Niamh O’Neill et al. · International Journal of Surgery Open access 26 Feb 2020 6,329
28 Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Wenhui Li, Michael John Moore, Natalya Yu. Vasilieva et al. · Nature Open access 26 Nov 2003 6,301
29 Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia Ali Mohamed Zaki, Sander van Boheemen, Theo M. Bestebroer et al. · New England Journal of Medicine Open access 18 Oct 2012 6,064
30 The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Hussin Alwan Rothan, Siddappa N. Byrareddy · Journal of Autoimmunity Open access 26 Feb 2020 6,056
31 Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases Tao Ai, Zhenlu Yang, Hongyan Hou et al. · Radiology Open access 26 Feb 2020 6,035
32 Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy Giacomo Grasselli et al. · JAMA Open access114 authors 6 Apr 2020 5,912
33 Origin and evolution of pathogenic coronaviruses Jie Cui, Fang Li, Zheng‐Li Shi · Nature Reviews Microbiology ReviewOpen access 10 Dec 2018 5,909
34 Vaccine hesitancy: Definition, scope and determinants Noni E. MacDonald · Vaccine Open access 17 Apr 2015 5,786
35 Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2 Renhong Yan, Yuanyuan Zhang, Yaning Li et al. · Science Open access 4 Mar 2020 5,612
36 A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 Bin Cao et al. · New England Journal of Medicine Open access 18 Mar 2020 5,526
37 The proximal origin of SARS-CoV-2 Kristian G. Andersen, Andrew Rambaut, Walter Ian Lipkin et al. · Nature Medicine Open access 17 Mar 2020 5,518
38 Characteristics of SARS-CoV-2 and COVID-19 Ben Hu, Hua Guo, Peng Zhou et al. · Nature Reviews Microbiology ReviewOpen access 6 Oct 2020 5,514
39 Detection of SARS-CoV-2 in Different Types of Clinical Specimens Wenling Wang, Yanli Xu, Ruqin Gao et al. · JAMA Open access 11 Mar 2020 5,352
40 Clinical and immunological features of severe and moderate coronavirus disease 2019 Guang Chen, Di Wu, Wei Guo et al. · Journal of Clinical Investigation Open access 27 Mar 2020 5,083
41 Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK Merryn Voysey et al. · The Lancet Open access765 authors 8 Dec 2020 5,030
42 The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status Yan-Rong Guo, Qing-Dong Cao, Zhong-Si Hong et al. · Military Medical Research Open access 13 Mar 2020 4,923
43 A SARS-CoV-2 protein interaction map reveals targets for drug repurposing David Ezra Gordon et al. · Nature Open access125 authors 30 Apr 2020 4,901
44 Presumed Asymptomatic Carrier Transmission of COVID-19 Yan Bai, Lingsheng Yao, Tao Wei et al. · JAMA Open access 21 Feb 2020 4,866
45 Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19) Willem Joost Wiersinga, Andrew Rhodes, ALLEN C. CHENG et al. · JAMA Open access 10 Jul 2020 4,842
46 Identification of a Novel Coronavirus in Patients with Severe Acute Respiratory Syndrome Christian Drosten et al. · New England Journal of Medicine Open access 14 May 2003 4,790
47 Temporal dynamics in viral shedding and transmissibility of COVID-19 Xi He et al. · Nature Medicine Open access 15 Apr 2020 4,705
48 Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus Yushun Wan, Jian Shang, Rachel L. Graham et al. · Journal of Virology Open access 31 Jan 2020 4,673
49 The trinity of COVID-19: immunity, inflammation and intervention Matthew Zirui Tay, Chek Meng Poh, Laurent Rénia et al. · Nature reviews. Immunology ReviewOpen access 28 Apr 2020 4,656
50 Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Wenhua Liang, Wei‐jie Guan, Ruchong Chen et al. · The Lancet Oncology Open access 14 Feb 2020 4,609

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.