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Most cited papers in SARS-CoV-2 detection and testing

What are the most cited papers in SARS-CoV-2 detection and testing?

The most cited paper in SARS-CoV-2 detection and testing is "Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area" (Safiya I. Richardson et al., 2020), with 9,915 citations. Next come "Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation" (9,833) and "Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR" (8,218).

Showing 50 of 100 papers. Every paper with more than 1,115 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Safiya I. Richardson et al. · JAMA Open access 22 Apr 2020 9,915
2 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett et al. · Science Open access 19 Feb 2020 9,833
3 Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Victor M. Corman et al. · Eurosurveillance Open access 23 Jan 2020 8,218
4 The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application Stephen A. Lauer, Kyra H. Grantz, Qifang Bi et al. · Annals of Internal Medicine Open access 9 Mar 2020 6,618
5 The proximal origin of SARS-CoV-2 Kristian G. Andersen, Andrew Rambaut, Walter Ian Lipkin et al. · Nature Medicine Open access 17 Mar 2020 5,518
6 Detection of SARS-CoV-2 in Different Types of Clinical Specimens Wenling Wang, Yanli Xu, Ruqin Gao et al. · JAMA Open access 11 Mar 2020 5,352
7 SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients Lirong Zou, Feng Ruan, Mingxing Huang et al. · New England Journal of Medicine Open access 20 Feb 2020 5,210
8 Presumed Asymptomatic Carrier Transmission of COVID-19 Yan Bai, Lingsheng Yao, Tao Wei et al. · JAMA Open access 21 Feb 2020 4,866
9 Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19) Willem Joost Wiersinga, Andrew Rhodes, ALLEN C. CHENG et al. · JAMA Open access 10 Jul 2020 4,842
10 Temporal dynamics in viral shedding and transmissibility of COVID-19 Xi He et al. · Nature Medicine Open access 15 Apr 2020 4,705
11 Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus Yushun Wan, Jian Shang, Rachel L. Graham et al. · Journal of Virology Open access 31 Jan 2020 4,673
12 Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus Bette Korber et al. · Cell Open access 2 Jul 2020 4,487
13 Epidemiology of COVID-19 Among Children in China Yuanyuan Dong, Xi Mo, Yabin Hu et al. · PEDIATRICS Open access 16 Mar 2020 4,312
14 SARS-CoV-2 variants, spike mutations and immune escape William T. Harvey, Alessandro M. Carabelli, Ben Jackson et al. · Nature Reviews Microbiology ReviewOpen access Jun 2021 3,930
15 Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Heshui Shi, Xiaoyu Han, Nanchuan Jiang et al. · The Lancet Infectious Diseases Open access 24 Feb 2020 3,853
16 Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Kelvin Kai‐Wang To et al. · The Lancet Infectious Diseases Open access 23 Mar 2020 3,383
17 Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal Laure Wynants et al. · BMJ ReviewOpen access 7 Apr 2020 3,312
18 Antibody responses to SARS-CoV-2 in patients with COVID-19 Quanxin Long et al. · Nature Medicine Open access 29 Apr 2020 3,121
19 Evidence for Gastrointestinal Infection of SARS-CoV-2 Fei Xiao, Meiwen Tang, Xiaobin Zheng et al. · Gastroenterology Open access 3 Mar 2020 2,868
20 Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices Andres W. Martinez, Scott T. Phillips, George M. Whitesides et al. · Analytical Chemistry 9 Dec 2009 2,678
21 Antibody Responses to SARS-CoV-2 in Patients With Novel Coronavirus Disease 2019 Juanjuan Zhao et al. · Clinical Infectious Diseases Open access 27 Mar 2020 2,676
22 Early dynamics of transmission and control of COVID-19: a mathematical modelling study Adam J. Kucharski et al. · The Lancet Infectious Diseases Open access 11 Mar 2020 2,676
23 Transmission routes of 2019-nCoV and controls in dental practice Xian Peng, Xin Feng Xu, Yuqing Li et al. · International Journal of Oral Science Open access 3 Mar 2020 2,509
24 Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis Alfonso Javier Rodriguez-Morales et al. · Travel Medicine and Infectious Disease ReviewOpen access Mar 2020 2,502
25 Prevalence of Asymptomatic SARS-CoV-2 Infection Daniel P. Oran, Eric J. Topol · Annals of Internal Medicine Open access 3 Jun 2020 2,483
26 The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study Kiesha Prem et al. · The Lancet Public Health Open access 25 Mar 2020 2,322
27 Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore Barnaby Edward Young et al. · JAMA Open access 3 Mar 2020 2,225
28 Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization Delphine Planas et al. · Nature Open access 8 Jul 2021 2,187
29 Convergent antibody responses to SARS-CoV-2 in convalescent individuals Davide F. Robbiani et al. · Nature Open access 18 Jun 2020 2,158
30 Chest CT for Typical Coronavirus Disease 2019 (COVID-19) Pneumonia: Relationship to Negative RT-PCR Testing Xingzhi Xie, Zheng Zhong, Wei Zhao et al. · Radiology Open access 12 Feb 2020 2,073
31 Consistent Detection of 2019 Novel Coronavirus in Saliva Kelvin Kai‐Wang To, Owen Tak-Yin Tsang, Cyril Chik‐Yan Yip et al. · Clinical Infectious Diseases Open access 10 Feb 2020 2,005
32 First confirmed detection of SARS-CoV-2 in untreated wastewater in Australia: A proof of concept for the wastewater surveillance of COVID-19 in the community Warish Ahmed, Nicola Z. Angel, Janette Edson et al. · The Science of The Total Environment Open access 17 Apr 2020 1,980
33 A serological assay to detect SARS-CoV-2 seroconversion in humans Fatima Amanat et al. · Nature Medicine Open access 12 May 2020 1,971
34 Stability of SARS-CoV-2 in different environmental conditions Alex W. H. Chin, Julie T. S. Chu, Mahen R A Perera et al. · The Lancet Microbe Open access 2 Apr 2020 1,951
35 Paper-based microfluidic point-of-care diagnostic devices Ali K. Yetisen, Muhammad Safwan Akram, Christopher Robin Lowe · Lab on a Chip 2013 1,945
36 Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients Angélica Jayk Bernal et al. · New England Journal of Medicine Open access 16 Dec 2021 1,930
37 Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China An Pan, Li Liu, Chaolong Wang et al. · JAMA Open access 10 Apr 2020 1,922
38 Viral dynamics in mild and severe cases of COVID-19 Yang Liu, Li-Meng Yan, La‐Gen Wan et al. · The Lancet Infectious Diseases Open access 19 Mar 2020 1,912
39 Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes Wei Zhang, Ronghui Du, Bei Li et al. · Emerging Microbes & Infections Open access 2020 1,906
40 Development and clinical application of a rapid IgM‐IgG combined antibody test for SARS‐CoV‐2 infection diagnosis Zhengtu Li et al. · Journal of Medical Virology Open access 27 Feb 2020 1,897
41 Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study Marina Pollán et al. · The Lancet Open access111 authors 6 Jul 2020 1,894
42 Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study Lei Pan, Mi Mu, Pengcheng Yang et al. · The American Journal of Gastroenterology Open access 14 Apr 2020 1,890
43 Rapid Detection of COVID-19 Causative Virus (SARS-CoV-2) in Human Nasopharyngeal Swab Specimens Using Field-Effect Transistor-Based Biosensor Giwan Seo, Geonhee Lee, Mi Jeong Kim et al. · ACS Nano Open access 15 Apr 2020 1,872
44 Diagnosing COVID-19: The Disease and Tools for Detection Buddhisha N. Udugama, Pranav Kadhiresan, Hannah N. Kozlowski et al. · ACS Nano Open access 30 Mar 2020 1,847
45 Spike mutation D614G alters SARS-CoV-2 fitness Jessica A. Plante et al. · Nature Open access 26 Oct 2020 1,770
46 Presence of SARS-Coronavirus-2 RNA in Sewage and Correlation with Reported COVID-19 Prevalence in the Early Stage of the Epidemic in The Netherlands Gertjan J. Medema, Leo Heijnen, Goffe Elsinga et al. · Environmental Science & Technology Letters Open access 20 May 2020 1,770
47 Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a nationwide vaccination campaign in Israel: an observational study using national surveillance data Eric J. Haas, Frederick J. Angulo, John M. McLaughlin et al. · The Lancet Open access May 2021 1,764
48 Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2 Yadi Zhou, Yuan Hou, Jiayu Shen et al. · Cell Discovery Open access 16 Mar 2020 1,739
49 Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19) Li Guo et al. · Clinical Infectious Diseases Open access 19 Mar 2020 1,730
50 Viral load of SARS-CoV-2 in clinical samples Yang Pan, Daitao Zhang, Peng Yang et al. · The Lancet Infectious Diseases Open access 24 Feb 2020 1,715

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.