Most cited papers in Science, Research, and Medicine
What are the most cited papers in Science, Research, and Medicine?
The most cited paper in Science, Research, and Medicine is "THE JOURNAL OF REPRODUCTIVE MEDICINE" (Diane M. Reddy, Sheldon A. Wasserman, 1999), with 2,517 citations. Next come "Growing points in ethology" (2,327) and "Advances in Experimental Medicine and Biology" (1,881).
Showing 50 of 100 papers. Every paper with more than 203 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | THE JOURNAL OF REPRODUCTIVE MEDICINE Diane M. Reddy, Sheldon A. Wasserman · AJN American Journal of Nursing | 1999 | 2,517 |
| 2 | Growing points in ethology Stephen J. Hutt · Animal Behaviour | Aug 1977 | 2,327 |
| 3 | Advances in Experimental Medicine and Biology G.G. Lunt · Neurochemistry International | 1986 | 1,881 |
| 4 | Policy: NIH to balance sex in cell and animal studies Janine A. Clayton, Francis S. Collins · Nature | May 2014 | 1,871 |
| 5 | Anticipation: Technoscience, life, affect, temporality Vincanne Adams, Michelle Murphy, Adele E. Clarke · Subjectivity | Sep 2009 | 1,076 |
| 6 | Chemistry: Chemical con artists foil drug discovery Jonathan B. Baell, Michael A. Walters · Nature | 22 Sep 2014 | 1,075 |
| 7 | Quantum chemistry program exchange Donald B. Boyd · Chemometrics and Intelligent Laboratory Systems | Mar 1987 | 1,068 |
| 8 | Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells Miguel Angel Esteban et al. · Cell stem cell | 2010 | 980 |
| 9 | Lost in translation: animal models and clinical trials in cancer treatment. Isabella W.Y. Mak, Nathan Evaniew, Michelle A. Ghert · PubMed | 2014 | 975 |
| 10 | Increased cell division as a cause of human cancer. Susan Preston‐Martin, MC Pike, R K Ross et al. · PubMed | Dec 1990 | 906 |
| 11 | The Need for a New Medical Model: A Challenge for Biomedicine George L. Engel · Psychodynamic Psychiatry | Sep 2012 | 893 |
| 12 | Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Stanley J. Korsmeyer, John R. Shutter, Deborah J. Veis et al. · PubMed | Dec 1993 | 874 |
| 13 | Executive summary: stages of reproductive aging workshop (STRAW) Michael R. Soules, Sherry Sherman, Estella C. Parrott et al. · Fertility and Sterility | Nov 2001 | 763 |
| 14 | Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall. Mat J.A.P. Daemen, Donna M. Lombardi, Fred T. Bosman et al. · Circulation Research | Feb 1991 | 743 |
| 15 | 2002 international ethical guidelines for biomedical research involving human subjects Sue Eckstein · Cambridge University Press eBooks | 20 Feb 2003 | 679 |
| 16 | Toxicology for the twenty-first century Thomas Härtung · Nature | Jul 2009 | 663 |
| 17 | P4 Medicine: How Systems Medicine Will Transform the Healthcare Sector and Society Mauricio Flores, Gustavo Glusman, Kristin Brogaard et al. · Personalized Medicine | Aug 2013 | 635 |
| 18 | DNA transformation. Craig C. Mello, Andrew Z. Fire · PubMed | 1995 | 624 |
| 19 | Challenge of portable power Bruno Scrosati · Nature | Feb 1995 | 618 |
| 20 | Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective Surovi Saikia, Manobjyoti Bordoloi · Current Drug Targets | 25 Oct 2018 | 583 |
| 21 | Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare Davide Cirillo, Silvina Catuara‐Solarz, Czuee Morey et al. · npj Digital Medicine | Jun 2020 | 550 |
| 22 | TELOMERASES Elizabeth Helen Blackburn · Annual Review of Biochemistry | Jun 1992 | 542 |
| 23 | Weapons of math destruction Thomas S. Woodson · Journal of Responsible Innovation | Aug 2018 | 514 |
| 24 | The logic of strategic ignorance Linsey McGoey · British Journal of Sociology | Sep 2012 | 505 |
| 25 | Discrimination as a consequence of genetic testing. Paul R. Billings, Melvin A. Kohn, Margaret de Cuevas et al. · PubMed | Mar 1992 | 487 |
| 26 | Genetic errors, cell proliferation, and carcinogenesis. Samuel M. Cohen, Leon B. Ellwein · PubMed | 15 Dec 1991 | 478 |
| 27 | Pharmaceutical innovation by the seven UK‐owned pharmaceutical companies (1964‐1985). RA Prentis, Yvonne Lis, SR Walker · British Journal of Clinical Pharmacology | Mar 1988 | 473 |
| 28 | Dose-Dependent Alterations in Androgen-Regulated Male Reproductive Development in Rats Exposed to Di(n-butyl) Phthalate during Late Gestation Eve Mylchreest · Toxicological Sciences | May 2000 | 453 |
| 29 | Chemical and physical carcinogenesis: advances and perspectives for the 1990s. C C Harris · PubMed | 15 Sep 1991 | 434 |
| 30 | The empathy cycle: Refinement of a nuclear concept. Godfrey T. Barrett‐Lennard · Journal of Counseling Psychology | 1981 | 426 |
| 31 | THE GROWTH AND MAINTENANCE OF TISSUE–CELL CULTURES IN FREE GAS EXCHANGE WITH THE ATMOSPHERE1 Albert Leibovitz · American Journal of Epidemiology | Sep 1963 | 424 |
| 32 | The Conduct of Inquiry in International Relations: Philosophy of Science and its Implications for the Study of World Politics Kristin M. Haugevik · Forum for Development Studies | Jun 2011 | 424 |
| 33 | Peto's Paradox: evolution's prescription for cancer prevention Aleah F. Caulin, Carlo C. Maley · Trends in Ecology & Evolution | 7 Feb 2011 | 405 |
| 34 | Cancer and cure: A critical analysis Partha Sarathi Roy, Bedangshu Saikia · Indian Journal of Cancer | 2016 | 402 |
| 35 | The Continuing Growth of Global Cooperation Networks in Research: A Conundrum for National Governments Caroline S. Wagner, Han Woo Park, Loet Leydesdorff · PLoS ONE | 21 Jul 2015 | 388 |
| 36 | Selling Stem Cells in the USA: Assessing the Direct-to-Consumer Industry Leigh G. Turner, Paul S. Knoepfler · Cell stem cell | 2 Jul 2016 | 383 |
| 37 | Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers. Stewart Sell, G. Barry Pierce · PubMed | 1994 | 381 |
| 38 | Sex as a Biological Variable: A 5-Year Progress Report and Call to Action Matthew E. Arnegard, Lori A. Whitten, Chyren Hunter et al. · Journal of Women s Health | 23 Jan 2020 | 372 |
| 39 | Cancer as a disease of old age: changing mutational and microenvironmental landscapes Ezio Laconi, Fabio Marongiu, James V. DeGregori · British Journal of Cancer | 11 Feb 2020 | 356 |
| 40 | A mutator phenotype in cancer. Lawrence A. Loeb · PubMed | 15 Apr 2001 | 352 |
| 41 | Impossible possible worlds vindicated Jaakko Hintikka · Journal of Philosophical Logic | Nov 1975 | 344 |
| 42 | Alzheimer’s disease Richard Hodson · Nature | 24 Jul 2018 | 339 |
| 43 | The 'rule of three' for fragment-based drug discovery: where are we now? Harren Jhoti, Glyn Williams, David C. Rees et al. · Nature Reviews Drug Discovery | 12 Jul 2013 | 337 |
| 44 | The individual strikes back Simon Blackburn · Synthese | Mar 1984 | 336 |
| 45 | Growing New Organs David J. Mooney, Antonios G. Mikos · Scientific American | Apr 1999 | 331 |
| 46 | The origins of human cancer: molecular mechanisms of carcinogenesis and their implications for cancer prevention and treatment--twenty-seventh G.H.A. Clowes memorial award lecture. I. Bernard Weinstein · PubMed | Aug 1988 | 324 |
| 47 | Progress in cancer research and therapy Arthur L. Frank · Environmental Research | Feb 1978 | 310 |
| 48 | Estimates of ozone depletion and skin cancer incidence to examine the Vienna Convention achievements Harry Slaper, Guus J. M. Velders, J. S. Daniel et al. · Nature | Nov 1996 | 309 |
| 49 | QUINOENZYMES IN BIOLOGY Judith Pollock Klinman, David Mu · Annual Review of Biochemistry | Jun 1994 | 308 |
| 50 | Genital Tumors among Men with Psoriasis Exposed to Psoralens and Ultraviolet A Radiation (PUVA) and Ultraviolet B Radiation Robert S. Stern, Members of the Photochemotherapy Follow-up Study* · New England Journal of Medicine | 19 Apr 1990 | 307 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.