Most cited papers in Statistical Methods in Clinical Trials
What are the most cited papers in Statistical Methods in Clinical Trials?
The most cited paper in Statistical Methods in Clinical Trials is "Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing" (Yoav Benjamini, Yosef Hochberg, 1995), with 112,351 citations. Next come "Bias in meta-analysis detected by a simple, graphical test" (57,774) and "Meta-analysis in clinical trials" (40,073).
Showing 50 of 99 papers. Every paper with more than 2,483 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing Yoav Benjamini, Yosef Hochberg · Journal of the Royal Statistical Society Series B (Statistical Methodology) | 1995 | 112,351 |
| 2 | Bias in meta-analysis detected by a simple, graphical test Matthias Egger, George Davey Smith, Martin Schneider et al. · BMJ | 13 Sep 1997 | 57,774 |
| 3 | Meta-analysis in clinical trials Rebecca DerSimonian, Nan M. Laird · Controlled Clinical Trials | Sep 1986 | 40,073 |
| 4 | Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement David Moher, Alessandro Liberati, Jennifer Tetzlaff et al. · Annals of Internal Medicine | 18 Aug 2009 | 38,212 |
| 5 | Quantifying heterogeneity in a meta‐analysis Julian P. T. Higgins, Simon G. Thompson · Statistics in Medicine | 21 May 2002 | 37,545 |
| 6 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1) E. A. Eisenhauer, P. Therasse, Jan Bogaerts et al. · European Journal of Cancer | 27 Dec 2008 | 30,125 |
| 7 | Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics Yoshinobu Kanda · Bone Marrow Transplantation | 3 Dec 2012 | 19,316 |
| 8 | Operating Characteristics of a Rank Correlation Test for Publication Bias Colin B. Begg, Madhuchhanda Mazumdar · Biometrics | Dec 1994 | 17,335 |
| 9 | Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease Nathan Mantel, William M. Haenszel · JNCI Journal of the National Cancer Institute | Apr 1959 | 14,868 |
| 10 | Trim and Fill: A Simple Funnel‐Plot–Based Method of Testing and Adjusting for Publication Bias in Meta‐Analysis Sue Duval, Richard L. Tweedie · Biometrics | Jun 2000 | 14,320 |
| 11 | Simultaneous Inference in General Parametric Models Torsten Hothorn, Frank Bretz, Peter H. Westfall · Biometrical Journal | 15 May 2008 | 14,308 |
| 12 | A Proportional Hazards Model for the Subdistribution of a Competing Risk Jason P. Fine, Malcolm H. Ray · Journal of the American Statistical Association | Jun 1999 | 13,914 |
| 13 | ANALYZING TABLES OF STATISTICAL TESTS William R. Rice · Evolution | 1989 | 13,907 |
| 14 | Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range Xiang Wan, Wenqian Wang, Jiming Liu et al. · BMC Medical Research Methodology | Dec 2014 | 11,974 |
| 15 | Correlation Coefficients: Appropriate Use and Interpretation Patrick R. Schober, Christa Boer, Lothar Andreas Schwarte · Anesthesia & Analgesia | 25 Feb 2018 | 11,012 |
| 16 | Multiple imputation using chained equations: Issues and guidance for practice Ian R. White, Patrick J Royston, ANGELA M. WOOD · Statistics in Medicine | 30 Nov 2010 | 10,013 |
| 17 | MULTIVARIABLE PROGNOSTIC MODELS: ISSUES IN DEVELOPING MODELS, EVALUATING ASSUMPTIONS AND ADEQUACY, AND MEASURING AND REDUCING ERRORS Frank E. Harrell, Kerry L. Lee, Daniel B. Mark · Statistics in Medicine | 29 Feb 1996 | 10,006 |
| 18 | A simulation study of the number of events per variable in logistic regression analysis Peter N. Peduzzi, John Concato, Elizabeth Kemper et al. · Journal of Clinical Epidemiology | Dec 1996 | 9,562 |
| 19 | Estimating the mean and variance from the median, range, and the size of a sample Stela Pudar Hozo, Benjamin Djulbegović, Iztok Hozo · BMC Medical Research Methodology | 20 Apr 2005 | 9,308 |
| 20 | A comparison of methods to test mediation and other intervening variable effects. David P. MacKinnon, Chondra M. Lockwood, Jeanne M. Hoffman et al. · Psychological Methods | 2002 | 9,252 |
| 21 | Measuring agreement in method comparison studies John M. Bland, Douglas G. Altman · Statistical Methods in Medical Research | Apr 1999 | 8,865 |
| 22 | A Test of Missing Completely at Random for Multivariate Data with Missing Values Roderick J. A. Little · Journal of the American Statistical Association | Dec 1988 | 8,570 |
| 23 | Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples Richard Peto, M. C. Pike, P. Armitage et al. · British Journal of Cancer | 1977 | 8,414 |
| 24 | SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials An‐Wen Chan, Jennifer Tetzlaff, Douglas G. Altman et al. · Annals of Internal Medicine | 5 Feb 2013 | 8,142 |
| 25 | Confidence Limits for the Indirect Effect: Distribution of the Product and Resampling Methods David P. MacKinnon, Chondra M. Lockwood, Jason G. Williams · Multivariate Behavioral Research | 2004 | 7,804 |
| 26 | Research Diagnostic Criteria Robert L. Spitzer · Archives of General Psychiatry | Jun 1978 | 6,996 |
| 27 | False-Positive Psychology Joseph P. Simmons, Leif D. Nelson, Uri Simonsohn · Psychological Science | 17 Oct 2011 | 6,878 |
| 28 | Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity‐score matched samples Peter C. Austin · Statistics in Medicine | 15 Sep 2009 | 6,815 |
| 29 | Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework Biomarkers Definitions Working Group · Clinical Pharmacology & Therapeutics | Mar 2001 | 6,746 |
| 30 | Nonparametric permutation tests for functional neuroimaging: A primer with examples Thomas E. Nichols, Andrew P. Holmes · Human Brain Mapping | 15 Oct 2001 | 6,548 |
| 31 | Practical methods for incorporating summary time-to-event data into meta-analysis Jayne F. Tierney, Lesley A. Stewart, Davina Ghersi et al. · Trials | 7 Jun 2007 | 6,491 |
| 32 | The ASA Statement on p -Values: Context, Process, and Purpose Ron Wasserstein, Nicole A. Lazar · The American Statistician | 7 Mar 2016 | 6,334 |
| 33 | A Direct Approach to False Discovery Rates John D. Storey · Journal of the Royal Statistical Society Series B (Statistical Methodology) | Aug 2002 | 5,849 |
| 34 | Using Effect Size—or Why the P Value Is Not Enough Gail M. Sullivan, Richard Feinn · Journal of Graduate Medical Education | Sep 2012 | 5,648 |
| 35 | Clinical End Points in Coronary Stent Trials Donald E. Cutlip, Stephan Windecker, Roxana Mehran et al. · Circulation | 30 Apr 2007 | 5,449 |
| 36 | The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials David Moher, Kenneth F. Schulz, Douglas G. Altman · The Lancet | Apr 2001 | 5,410 |
| 37 | Assessing the Performance of Prediction Models Ewout Willem Steyerberg, Andrew Julian Vickers, Nancy R. Cook et al. · Epidemiology | 9 Dec 2009 | 5,171 |
| 38 | Statistics and Causal Inference Paul W. Holland · Journal of the American Statistical Association | Dec 1986 | 5,156 |
| 39 | Distribution Theory for Glass's Estimator of Effect size and Related Estimators Larry Vernon Hedges · Journal of Educational Statistics | Jun 1981 | 5,087 |
| 40 | Thresholding of Statistical Maps in Functional Neuroimaging Using the False Discovery Rate Christopher R. Genovese, Nicole A. Lazar, Thomas E. Nichols · NeuroImage | Apr 2002 | 5,056 |
| 41 | A sharper Bonferroni procedure for multiple tests of significance Yosef Hochberg · Biometrika | 1988 | 4,776 |
| 42 | Depression: a new animal model sensitive to antidepressant treatments Roger D. Porsolt, Manuel Pichon, Maurice Jalfre · Nature | Apr 1977 | 4,476 |
| 43 | STAMP: statistical analysis of taxonomic and functional profiles Donovan H. Parks, Gene W. Tyson, Philip Hugenholtz et al. · Bioinformatics | 23 Jul 2014 | 4,381 |
| 44 | Controlling the false discovery rate in behavior genetics research Yoav Benjamini, Dan Drai, Gregory I. Elmer et al. · Behavioural Brain Research | Nov 2001 | 4,264 |
| 45 | Equivalence of the Mediation, Confounding and Suppression Effect David P. MacKinnon, Jennifer L. Krull, Chondra M. Lockwood · Prevention Science | Dec 2000 | 4,183 |
| 46 | Prior distributions for variance parameters in hierarchical models (comment on article by Browne and Draper) Andrew Gelman · Bayesian Analysis | Sep 2006 | 4,179 |
| 47 | Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range Dehui Luo, Xiang Wan, Jiming Liu et al. · Statistical Methods in Medical Research | 27 Sep 2016 | 4,151 |
| 48 | Bayesian t tests for accepting and rejecting the null hypothesis Jeffrey N. Rouder, Paul L. Speckman, Dongchu Sun et al. · Psychonomic Bulletin & Review | 16 Mar 2009 | 4,016 |
| 49 | Statistical notes for clinical researchers: assessing normal distribution (2) using skewness and kurtosis Hae‐Yeong Kim · Restorative Dentistry & Endodontics | 2013 | 3,996 |
| 50 | Effect size, confidence interval and statistical significance: a practical guide for biologists Shinichi Nakagawa, Innes C. Cuthill · Biological reviews/Biological reviews of the Cambridge Philosophical Society | 18 Oct 2007 | 3,897 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.