Most cited papers in Sulfur Compounds in Biology
What are the most cited papers in Sulfur Compounds in Biology?
The most cited paper in Sulfur Compounds in Biology is "Tissue sulfhydryl groups" (George L. Ellman, 1959), with 26,451 citations. Next come "Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids" (12,147) and "Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues" (6,083).
Showing 50 of 100 papers. Every paper with more than 993 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Tissue sulfhydryl groups George L. Ellman · Archives of Biochemistry and Biophysics | May 1959 | 26,451 |
| 2 | Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids Laura C. Green, David A. Wagner, Joseph A. Glogowski et al. · Analytical Biochemistry | Oct 1982 | 12,147 |
| 3 | Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues Frank Tietze · Analytical Biochemistry | Mar 1969 | 6,083 |
| 4 | Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine Owen W. Griffith · Analytical Biochemistry | Jul 1980 | 4,625 |
| 5 | Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver M MORON, Joseph William DePierre, Bengt Mannervik · Biochimica et Biophysica Acta (BBA) - General Subjects | 4 Jan 1979 | 4,221 |
| 6 | A fluorometric method for determination of oxidized and reduced glutathione in tissues Paul J. Hissin, Russell Hilf · Analytical Biochemistry | Jul 1976 | 4,127 |
| 7 | Glutathione Metabolism and Its Implications for Health Guoyao Wu, Joanne R. Lupton, Nancy D. Turner et al. · Journal of Nutrition | Mar 2004 | 3,876 |
| 8 | A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation Özcan Erel · Clinical Biochemistry | 6 Mar 2004 | 2,933 |
| 9 | Oxidative Stress in Cancer John David Hayes, Albena T. Dinkova‐Kostova, Kenneth D. Tew · Cancer Cell | 9 Jul 2020 | 2,652 |
| 10 | Glutathione: Overview of its protective roles, measurement, and biosynthesis Henry Jay Forman, Hongqiao Zhang, Alessandra Rinna · Molecular Aspects of Medicine | 31 Aug 2008 | 2,644 |
| 11 | Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi et al. · Nature Medicine | 7 May 2007 | 2,586 |
| 12 | Structure, mechanism and regulation of peroxiredoxins Zachary A. Wood, Ewald Schröder, J. Robin Harris et al. · Trends in Biochemical Sciences | 2003 | 2,553 |
| 13 | Physiological functions of thioredoxin and thioredoxin reductase Elias S.J. Arnér, Arne Holmgren · European Journal of Biochemistry | Oct 2000 | 2,553 |
| 14 | Peroxynitrite oxidation of sulfhydryls. Rafael Radí, Joseph S. Beckman, Ken Bush et al. · Journal of Biological Chemistry | Mar 1991 | 2,493 |
| 15 | A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds Stuart A. Lipton, Yun‐Beom Choi, Zhuo‐Hua Pan et al. · Nature | Aug 1993 | 2,449 |
| 16 | H 2 S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase Guangdong Yang, Lingyun Wu, Bo Jiang et al. · Science | 23 Oct 2008 | 2,317 |
| 17 | Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method Irfan Rahman, Aruna Kode, Saibal K. Biswas · Nature Protocols | Dec 2006 | 2,277 |
| 18 | The possible role of hydrogen sulfide as an endogenous neuromodulator K. Abe, Hideo Kimura · Journal of Neuroscience | Feb 1996 | 2,252 |
| 19 | Glutathione synthesis Shelly Chi-Loo Lu · Biochimica et Biophysica Acta (BBA) - General Subjects | 17 Sep 2012 | 2,197 |
| 20 | Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease Robert Clarke, Leslie Daly, Killian Robinson et al. · New England Journal of Medicine | 25 Apr 1991 | 2,180 |
| 21 | Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis L. Joseph Su, Jiahao Zhang, Hernando Gómez et al. · Oxidative Medicine and Cellular Longevity | 13 Oct 2019 | 2,176 |
| 22 | The thioredoxin antioxidant system Jun Lu, Arne Holmgren · Free Radical Biology and Medicine | 27 Jul 2013 | 2,078 |
| 23 | Purification and characterization of the flavoenzyme glutathione reductase from rat liver. Inger Carlberg, Bengt Mannervik · Journal of Biological Chemistry | Jul 1975 | 2,027 |
| 24 | Glutathione metabolism and its selective modification. A Meister · Journal of Biological Chemistry | Nov 1988 | 2,026 |
| 25 | The importance of glutathione in human disease Danyelle M. Townsend, Kenneth D. Tew, Haïm Tapiero · Biomedicine & Pharmacotherapy | May 2003 | 2,015 |
| 26 | DNA Damage and Oxygen Radical Toxicity James A. Imlay, Stuart Linn · Science | 3 Jun 1988 | 1,977 |
| 27 | Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed Rui Ting Wang · Physiological Reviews | Apr 2012 | 1,948 |
| 28 | The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener Weimin Zhao, Jing Zhang, Yanjie Lu et al. · The EMBO Journal | Nov 2001 | 1,937 |
| 29 | Two's company, three's a crowd: can H 2 S be the third endogenous gaseous transmitter? Rui Ting Wang · The FASEB Journal | 30 Oct 2002 | 1,807 |
| 30 | Reactive oxygen species in living systems: Source, biochemistry, and role in human disease Barry B. Halliwell · The American Journal of Medicine | Sep 1991 | 1,807 |
| 31 | Colorimetric determination of phospholipids with ammonium ferrothiocyanate John C. Stewart · Analytical Biochemistry | May 1980 | 1,791 |
| 32 | The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid Okezie I. Aruoma, Barry B. Halliwell, Brigid M. Hoey et al. · Free Radical Biology and Medicine | 1989 | 1,780 |
| 33 | A novel automated method to measure total antioxidant response against potent free radical reactions Özcan Erel · Clinical Biochemistry | 2 Dec 2003 | 1,772 |
| 34 | Glutathione and its role in cellular functions Helmut Sies · Free Radical Biology and Medicine | Nov 1999 | 1,737 |
| 35 | Redefining Oxidative Stress Dean P. Jones · Antioxidants and Redox Signaling | Sep 2006 | 1,721 |
| 36 | Metabolism and functions of glutathione in brain Ralf Dringen · Progress in Neurobiology | Dec 2000 | 1,710 |
| 37 | Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). Owen W. Griffith, A Meister · Journal of Biological Chemistry | Aug 1979 | 1,698 |
| 38 | Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules Min Hee Lee, Jong Seung Kim, Jonathan L. Sessler · Chemical Society Reviews | 6 Oct 2014 | 1,663 |
| 39 | Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate Michael A. Marletta, Poksyn S. Yoon, Radha Iyengar et al. · Biochemistry | Nov 1988 | 1,610 |
| 40 | Hydrogen Peroxide Sensing and Signaling Elizabeth A. Veal, Alison M. Day, Brian A. Morgan · Molecular Cell | Apr 2007 | 1,608 |
| 41 | Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide David A. Wink, James B. Mitchell · Free Radical Biology and Medicine | Sep 1998 | 1,604 |
| 42 | Drinking Water Nitrate and Human Health: An Updated Review Mary H. Ward, Rena R. Jones, Jean D. Brender et al. · International Journal of Environmental Research and Public Health | 23 Jul 2018 | 1,577 |
| 43 | Fluorescent and colorimetric probes for detection of thiols Xiaoqiang Chen, Ying Mei Zhou, Xiaojun Peng et al. · Chemical Society Reviews | 2010 | 1,576 |
| 44 | Role of nitric oxide synthesis in macrophage antimicrobial activity Carl Nathan, John B. Hibbs · Current Opinion in Immunology | 1991 | 1,541 |
| 45 | Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress John David Hayes, Lesley I. McLellan · Free Radical Research | 1999 | 1,534 |
| 46 | Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations William Perry Arnold, Chandra K. Mittal, Shoji Katsuki et al. · Proceedings of the National Academy of Sciences | Aug 1977 | 1,460 |
| 47 | The changing faces of glutathione, a cellular protagonist Alfonso Pompella, Athanase Visvikis, Aldo Paolicchi et al. · Biochemical Pharmacology | 11 Sep 2003 | 1,375 |
| 48 | iNOS-mediated nitric oxide production and its regulation Fügen Aktan · Life Sciences | 8 May 2004 | 1,372 |
| 49 | Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-Ratten H. Druckrey, R. Preußmann, Stan Ivankovic et al. · Journal of Cancer Research and Clinical Oncology | 1967 | 1,355 |
| 50 | Assay of glutathione reductase in crude tissue homogenates using 5,5′-dithiobis(2-nitrobenzoic acid) Ivan K. Smith, Thomas L. Vierheller, Carol A. Thorne · Analytical Biochemistry | Dec 1988 | 1,351 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.