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Most cited papers in Synthetic Organic Chemistry Methods

Synthetic Organic Chemistry Methods

What are the most cited papers in Synthetic Organic Chemistry Methods?

The most cited paper in Synthetic Organic Chemistry Methods is "The Atom Economy—A Search for Synthetic Efficiency" (BM Trost, 1991), with 4,807 citations. Next come "Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010" (4,699) and "Autonomic healing of polymer composites" (4,540).

Showing 50 of 100 papers. Every paper with more than 1,069 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 The Atom Economy—A Search for Synthetic Efficiency BM Trost · Science 6 Dec 1991 4,807
2 Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010 David J. Newman, Gordon M. L. Cragg · Journal of Natural Products Open access 8 Feb 2012 4,699
3 Autonomic healing of polymer composites Scott R. White, Nancy R. Sottos, Philippe H. Geubelle et al. · Nature 15 Feb 2001 4,540
4 New Polymer Synthesis by Nitroxide Mediated Living Radical Polymerizations Craig J. Hawker, Anton W. Bosman, Eva M. Harth · Chemical Reviews Review 25 Oct 2001 3,812
5 N-Heterocyclic Carbenes: A New Concept in Organometallic Catalysis Wolfgang Anton Herrmann · Angewandte Chemie International Edition 15 Apr 2002 3,776
6 Stable Carbenes Didier Bourissou, Olivier Guerret, François P. Gabbaı̈ et al. · Chemical Reviews Review 22 Dec 1999 3,607
7 The Development of L 2 X 2 RuCHR Olefin Metathesis Catalysts: An Organometallic Success Story Tina M. Trnka, Robert Howard Grubbs · Accounts of Chemical Research 4 Nov 2000 3,553
8 Synthesis and Activity of a New Generation of Ruthenium-Based Olefin Metathesis Catalysts Coordinated with 1,3-Dimesityl-4,5-dihydroimidazol-2-ylidene Ligands Matthias Scholl, Sheng Li Ding, Choon Woo Lee et al. · Organic Letters 13 Aug 1999 3,452
9 Late-Metal Catalysts for Ethylene Homo- and Copolymerization Steven D. Ittel, Lynda K. Johnson, Maurice Brookhart · Chemical Reviews Review 25 Mar 2000 3,145
10 Organocatalysis by N-Heterocyclic Carbenes Dieter Enders, Oliver Niemeier, Alexander Henseler · Chemical Reviews Review 23 Oct 2007 3,059
11 N-Heterocyclic Carbenes in Late Transition Metal Catalysis Silvia Díez‐González, Nicolas Marion, Steven P. Nolan · Chemical Reviews Review 9 Jul 2009 3,056
12 Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995–1998 Akira Suzuki · Journal of Organometallic Chemistry Mar 1999 2,918
13 Heterocyclic Carbenes: Synthesis and Coordination Chemistry F. Ekkehardt Hahn, Mareike C. Jahnke · Angewandte Chemie International Edition 8 Apr 2008 2,769
14 Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands Rubén Martı́n, Stephen L. Buchwald · Accounts of Chemical Research Open access 12 Jul 2008 2,663
15 Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis Thomas J. Kwiatkowski et al. · Science 26 Feb 2009 2,597
16 Advances in Non-Metallocene Olefin Polymerization Catalysis Vernon C. Gibson, Stefan K. Spitzmesser · Chemical Reviews Review 17 Dec 2002 2,513
17 A Rapid Esterification by Means of Mixed Anhydride and Its Application to Large-ring Lactonization Junji Inanaga, Kuniko Hirata, Hiroko SAEKI et al. · Bulletin of the Chemical Society of Japan Jul 1979 2,174
18 Synthesis and Applications of RuCl2(CHR‘)(PR3)2: The Influence of the Alkylidene Moiety on Metathesis Activity Peter A. Schwab, Robert Howard Grubbs, Joseph W. Ziller · Journal of the American Chemical Society 1996 2,106
19 Recent advances in olefin metathesis and its application in organic synthesis Robert Howard Grubbs, Sukbok Chang · Tetrahedron Apr 1998 2,101
20 Cascade Reactions in Total Synthesis Kyriacos Costa Nicolaou, David J. Edmonds, Paul G. Bulger · Angewandte Chemie International Edition 30 Oct 2006 2,093
21 Simple Method for the Esterification of Carboxylic Acids Bernhard Neises, Wölfgang Steglich · Angewandte Chemie International Edition in English Jul 1978 2,064
22 Nomenclature of Amphiboles BERNARD ELGEY LEAKE · Mineralogical Magazine Open access Dec 1978 2,062
23 Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes Darrin M. Flanigan, Fedor Romanov‐Michailidis, Nicholas A. White et al. · Chemical Reviews ReviewOpen access 20 May 2015 2,058
24 Gold-Catalyzed Cycloisomerizations of Enynes: A Mechanistic Perspective Eloísa Jiménez‐Núñez, Antonio M. Echavarren · Chemical Reviews Review 18 Jul 2008 2,056
25 Ruthenium-Based Heterocyclic Carbene-Coordinated Olefin Metathesis Catalysts Georgios C. Vougioukalakis, Robert Howard Grubbs · Chemical Reviews Review 14 Dec 2009 2,017
26 Efficient and Recyclable Monomeric and Dendritic Ru-Based Metathesis Catalysts Steven B. Garber, Jason S. Kingsbury, Brian Lawrence Gray et al. · Journal of the American Chemical Society Aug 2000 2,013
27 Olefin Metathesis and Beyond Alois Fürstner · Angewandte Chemie International Edition Sep 2000 1,945
28 Cocatalysts for Metal-Catalyzed Olefin Polymerization: Activators, Activation Processes, and Structure−Activity Relationships Eugene You-Xian Chen, Tobin Jay Marks · Chemical Reviews Review 28 Mar 2000 1,935
29 Polyurethane types, synthesis and applications – a review John Olabode Akindoyo, M.D.H. Beg, Suriati Binti Ghazali et al. · RSC Advances 2016 1,842
30 Stereoselective Cyclopropanation Reactions H. Lebel, Jean-François Marcoux, Carmela Molinaro et al. · Chemical Reviews Review Apr 2003 1,796
31 The Search for New-Generation Olefin Polymerization Catalysts: Life beyond Metallocenes George J. P. Britovsek, Vernon C. Gibson, Duncan F. Wass · Angewandte Chemie International Edition 15 Feb 1999 1,771
32 Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity Ruth Dorel, Antonio M. Echavarren · Chemical Reviews ReviewOpen access 6 Apr 2015 1,732
33 Natural Product Synthesis Using Multicomponent Reaction Strategies B. Barry Touré, Dennis G. Hall · Chemical Reviews Review 29 May 2009 1,707
34 Enantioselective Mannich‐Type Reaction Catalyzed by a Chiral Brønsted Acid Takahiko Akiyama, Junji Itoh, Koji Yokota et al. · Angewandte Chemie International Edition 9 Mar 2004 1,670
35 Polyketide biosynthesis: a millennium review James Staunton, Kira J. Weissman · Natural Product Reports 2001 1,652
36 Asymmetric Organocatalytic Domino Reactions Dieter Enders, Christoph Grondal, Matthias R. M. Hüttl · Angewandte Chemie International Edition 16 Jan 2007 1,622
37 Donor−Acceptor-Substituted Cyclopropane Derivatives and Their Application in Organic Synthesis Hans‐Ulrich Reißig, Reinhold Zimmer · Chemical Reviews Review 21 Feb 2003 1,592
38 Organocatalytic cascade reactions as a new tool in total synthesis Christoph Grondal, Matthieu Jeanty, Dieter Enders · Nature Chemistry 19 Feb 2010 1,583
39 Platinum Group Organometallics Based on “Pincer” Complexes: Sensors, Switches, and Catalysts Martin Albrecht, Gerard van Koten · Angewandte Chemie International Edition 15 Oct 2001 1,573
40 A General Model for Selectivity in Olefin Cross Metathesis Arnab Chatterjee, Tae‐Lim Choi, Daniel P. Sanders et al. · Journal of the American Chemical Society 20 Aug 2003 1,541
41 Living ring-opening metathesis polymerization Christopher W. Bielawski, Robert Howard Grubbs · Progress in Polymer Science 11 Oct 2006 1,518
42 Metal‐Catalyzed Enantioselective Allylation in Asymmetric Synthesis Zhan Ling Lu, Shengming Ma · Angewandte Chemie International Edition 29 Oct 2007 1,507
43 Recent advances in dynamic covalent chemistry Yinghua Jin, Chao Yu, Ryan J. Denman et al. · Chemical Society Reviews Review 2013 1,496
44 A Planning Strategy for Diversity‐Oriented Synthesis Martin D. Burke, Stuart L. Schreiber · Angewandte Chemie International Edition 17 Dec 2003 1,490
45 The osmium-catalyzed asymmetric dihydroxylation: a new ligand class and a process improvement Karl Barry Sharpless, Willi M. Amberg, Youssef L. Bennani et al. · The Journal of Organic Chemistry May 1992 1,483
46 A Series of Well‐Defined Metathesis Catalysts–Synthesis of [RuCl2(CHR′)(PR3)2] and Its Reactions Peter A. Schwab, Marcia B. France, Joseph W. Ziller et al. · Angewandte Chemie International Edition in English 2 Oct 1995 1,482
47 The Asymmetric Intramolecular Heck Reaction in Natural Product Total Synthesis Amy B. Dounay, Larry E. Overman · Chemical Reviews Review 8 Jul 2003 1,479
48 Organocatalytic Ring-Opening Polymerization Nahrain E. Kamber, W. G. Jeong, Robert M. Waymouth et al. · Chemical Reviews Review 8 Nov 2007 1,477
49 Self-Assembled Nanoreactors Dennis M. Vriezema, Marta Comellas Aragonès, Johannes A. A. W. Elemans et al. · Chemical Reviews Review Mar 2005 1,462
50 Concurrent Tandem Catalysis J.-C. Wasilke, Stephen James Obrey, R. Tom Baker et al. · Chemical Reviews Review 19 Feb 2005 1,462

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.