Most cited papers in Trace Elements in Health
What are the most cited papers in Trace Elements in Health?
The most cited paper in Trace Elements in Health is "Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death" (Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al., 2012), with 19,018 citations. Next come "Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation." (9,552) and "Selenium: Biochemical Role as a Component of Glutathione Peroxidase" (7,831).
Showing 50 of 99 papers. Every paper with more than 1,367 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell | May 2012 | 19,018 |
| 2 | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology | Nov 1992 | 9,552 |
| 3 | Selenium: Biochemical Role as a Component of Glutathione Peroxidase John T. Rotruck, Alun Lloyd Pope, Howard E. Ganther et al. · Science | 9 Feb 1973 | 7,831 |
| 4 | Adult sibling experience, roles, relationshhips and future concerns - a review of the literature in learning disabilities C Catassi et al. · Institutional Research Information System University of Turin (University of Turin) | 1996 | 5,515 |
| 5 | Prions Stanley Ben Prusiner · Proceedings of the National Academy of Sciences | 10 Nov 1998 | 5,428 |
| 6 | Metals, Toxicity and Oxidative Stress Marián Valko, Harry Morris, M Cronin · Current Medicinal Chemistry | 29 Apr 2005 | 5,027 |
| 7 | Copper induces cell death by targeting lipoylated TCA cycle proteins Peter Tsvetkov, Shannon Coy, Boryana Petrova et al. · Science | 17 Mar 2022 | 5,017 |
| 8 | Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization Elizabeta Nemeth, Marie S. Tuttle, Julie Powelson et al. · Science | 28 Oct 2004 | 4,836 |
| 9 | Caspases: the executioners of apoptosis Gerald M. Cohen · Biochemical Journal | 15 Aug 1997 | 4,755 |
| 10 | The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature | Feb 1987 | 4,640 |
| 11 | Oxidative mechanisms in the toxicity of metal ions SIDNEY J. STOHS, D. Bagchi · Free Radical Biology and Medicine | Feb 1995 | 4,225 |
| 12 | The importance of selenium to human health Margaret P. Rayman · The Lancet | Jul 2000 | 4,171 |
| 13 | Emerging roles of caspase-3 in apoptosis Alan George Porter, Reiner U. Jänicke · Cell Death and Differentiation | 28 Jan 1999 | 3,932 |
| 14 | Selenium and human health Margaret P. Rayman · The Lancet | 28 Feb 2012 | 3,542 |
| 15 | Glutathione peroxidase activity in selenium-deficient rat liver Richard A Lawrence, Raymond F. Burk · Biochemical and Biophysical Research Communications | Aug 1976 | 3,541 |
| 16 | Advances in metal-induced oxidative stress and human disease Klaudia Jomová, Marián Valko · Toxicology | 16 Mar 2011 | 3,223 |
| 17 | Cloning and characterization of a mammalian proton-coupled metal-ion transporter Hiromi Gunshin, Bryan Mackenzie, Urs V. Berger et al. · Nature | 31 Jul 1997 | 3,203 |
| 18 | The biochemical basis of zinc physiology Bert L. Vallée, Kenneth H. Falchuk · Physiological Reviews | 1993 | 3,019 |
| 19 | Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis William C. Earnshaw, Luis Miguel Martins, Scott H. Kaufmann · Annual Review of Biochemistry | Jun 1999 | 2,776 |
| 20 | The Effects of Cadmium Toxicity Giuseppe Genchi, Maria Stefania Sinicropi, Graziantonio Lauria et al. · International Journal of Environmental Research and Public Health | 26 May 2020 | 2,707 |
| 21 | The ferritins: molecular properties, iron storage function and cellular regulation Pauline M. Harrison, Paolo Arosio · Biochimica et Biophysica Acta (BBA) - Bioenergetics | Jul 1996 | 2,698 |
| 22 | Structural and Functional Aspects of Metal Sites in Biology R. H. Holm, Pierre Kennepohl, Edward I. Solomon · Chemical Reviews | 1996 | 2,548 |
| 23 | P HYTOCHELATINS AND M ETALLOTHIONEINS : Roles in Heavy Metal Detoxification and Homeostasis Christopher S. Cobbett, Peter B. Goldsbrough · Annual Review of Plant Biology | Jun 2002 | 2,509 |
| 24 | The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme Yuan Ji · Cell | 19 Nov 1993 | 2,501 |
| 25 | The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases Michael Karin · Journal of Biological Chemistry | Jul 1995 | 2,458 |
| 26 | The role of iron and reactive oxygen species in cell death Scott J. Dixon, Brent R. Stockwell · Nature Chemical Biology | 17 Dec 2013 | 2,410 |
| 27 | Oxidative Stress Hypothesis in Alzheimer's Disease William R. Markesbery · Free Radical Biology and Medicine | 1997 | 2,390 |
| 28 | Characterization of Mammalian Selenoproteomes Gregory V. Kryukov, Sergi Castellano, Sergey V. Novoselov et al. · Science | 29 May 2003 | 2,385 |
| 29 | A multidrug resistance transporter from human MCF-7 breast cancer cells L. Austin Doyle, Weidong Yang, Lynne V. Abruzzo et al. · Proceedings of the National Academy of Sciences | 22 Dec 1998 | 2,333 |
| 30 | Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. K M Pan, M. A. Baldwin, Jack T Nguyen et al. · Proceedings of the National Academy of Sciences | Dec 1993 | 2,280 |
| 31 | IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin Elizabeta Nemeth, Seth Rivera, Victoria R. Gabayan et al. · Journal of Clinical Investigation | May 2004 | 2,242 |
| 32 | Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Joseph T. Jarrett, Peter T. Lansbury · Cell | Jun 1993 | 2,194 |
| 33 | Enrichment of cereal grains with zinc: Agronomic or genetic biofortification? İsmail Çakmak · Plant and Soil | 27 Nov 2007 | 2,183 |
| 34 | Copper toxicity, oxidative stress, and antioxidant nutrients Lisa M. Gaetke · Toxicology | 2 Jun 2003 | 2,176 |
| 35 | Toxicity of lead: a review with recent updates Gagan D. Flora, Deepesh Gupta, Archana Tiwari · Interdisciplinary Toxicology | 9 Nov 2012 | 2,172 |
| 36 | Two to Tango: Regulation of Mammalian Iron Metabolism Matthias W. Hentze, Martina Ulrike Muckenthaler, Bruno Galy et al. · Cell | Jul 2010 | 2,142 |
| 37 | Copper, iron and zinc in Alzheimer's disease senile plaques Mark A. Lovell, J. David Robertson, William J. Teesdale et al. · Journal of the Neurological Sciences | Jun 1998 | 2,128 |
| 38 | Disorders of Iron Metabolism Nancy C. Andrews · New England Journal of Medicine | 23 Dec 1999 | 2,127 |
| 39 | Mice devoid of PrP are resistant to scrapie Hansruedi Büeler, Adriano Aguzzi, Andreas W. Sailer et al. · Cell | Jul 1993 | 2,107 |
| 40 | Intellectual Impairment in Children with Blood Lead Concentrations below 10 μg per Deciliter Richard L. Canfield, Charles Henderson, Deborah A. Cory‐Slechta et al. · New England Journal of Medicine | 16 Apr 2003 | 2,089 |
| 41 | Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging Emily L. Que, Dylan Wythe Domaille, Christopher J. Chang · Chemical Reviews | 22 Apr 2008 | 2,072 |
| 42 | Mechanisms and Functions of Cell Death Ronald E. Ellis, Junying Yuan, H. Robert Horvitz · Annual Review of Cell Biology | Nov 1991 | 2,067 |
| 43 | The Epidemiology of Global Micronutrient Deficiencies Regan Lucas Bailey, Keith P. West, Robert E. Black · Annals of Nutrition and Metabolism | 2015 | 2,053 |
| 44 | Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements Wes Lee, Pamela J. Mitchell, Robert Tjian · Cell | Jun 1987 | 2,047 |
| 45 | Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) Sharon M. Moe, Tilman Bernhard Drüeke, John Alastair Cunningham et al. · Kidney International | 26 Apr 2006 | 1,997 |
| 46 | Developmental neurotoxicity of industrial chemicals Philippe Grandjean, PJ Landrigan · The Lancet | 14 Nov 2006 | 1,978 |
| 47 | The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene Peter C. Bull, Gordon R. Thomas, Johanna M. Rommens et al. · Nature Genetics | Dec 1993 | 1,966 |
| 48 | The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc Jeremy M Berg, Yigong Shi · Science | 23 Feb 1996 | 1,956 |
| 49 | Lead toxicity: a review Ab Latif Wani, Anjum Ara, Jawed Ahmad Usmani · Interdisciplinary Toxicology | Jun 2015 | 1,945 |
| 50 | Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells Wan Seok Yang, Brent R. Stockwell · Chemistry & Biology | Mar 2008 | 1,916 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.