Most cited papers in Veterinary Pharmacology and Anesthesia
What are the most cited papers in Veterinary Pharmacology and Anesthesia?
The most cited paper in Veterinary Pharmacology and Anesthesia is "Ethical guidelines for investigations of experimental pain in conscious animals" (Manfred Zimmermann, 1983), with 7,814 citations. Next come "A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia" (5,230) and "Physiological Parameters in Laboratory Animals and Humans" (2,937).
Showing 50 of 99 papers. Every paper with more than 382 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Ethical guidelines for investigations of experimental pain in conscious animals Manfred Zimmermann · Pain | Jun 1983 | 7,814 |
| 2 | A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Kenneth Hargreaves, Ronald A. Dubner, Frederick J. Brown et al. · Pain | 1988 | 5,230 |
| 3 | Physiological Parameters in Laboratory Animals and Humans Brian E. Davies, Tim Morris · Pharmaceutical Research | Jul 1993 | 2,937 |
| 4 | The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats David Dubuisson, Stephen G. Dennis · Pain | Oct 1977 | 2,538 |
| 5 | Pharmacokinetics of a novel formulation of ivermectin after administration to goats Aranzazu González, Ana M. Sahagún, M. José Diez et al. · American Journal of Veterinary Research | Feb 2006 | 1,768 |
| 6 | Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients A Randomized Trial Richard R. Riker · JAMA | 2 Feb 2009 | 1,682 |
| 7 | A good practice guide to the administration of substances and removal of blood, including routes and volumes Karl‐Heinz Diehl, Robin Hull, David B. Morton et al. · Journal of Applied Toxicology | 2001 | 1,569 |
| 8 | The Effects of Increasing Plasma Concentrations of Dexmedetomidine in Humans Thomas J. Ebert, Judith Hall, Jill A. Barney et al. · Anesthesiology | Aug 2000 | 1,407 |
| 9 | Swine as Models in Biomedical Research and Toxicology Testing M. Michael Swindle, Andy Makin, A. J. Herron et al. · Veterinary Pathology | 25 Mar 2011 | 1,387 |
| 10 | Methods Used to Evaluate Pain Behaviors in Rodents Jennifer R. Deuis, Lucie Sam Dvorakova, Irina Vetter · Frontiers in Molecular Neuroscience | 5 Sep 2017 | 1,312 |
| 11 | Clinical Pharmacology of Tramadol Stefan Grond, Armin Sablotzki · Clinical Pharmacokinetics | 2004 | 1,285 |
| 12 | Influence of Age and Gender on the Pharmacokinetics and Pharmacodynamics of Remifentanil Charles F. Minto, Thomas W. Schnider, Talmage D. Egan et al. · Anesthesiology | 1997 | 1,221 |
| 13 | Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic. Robert B. Raffa, Elmar Friderichs, Wolfgang Reimann et al. · Journal of Pharmacology and Experimental Therapeutics | 1992 | 1,174 |
| 14 | Animal Physiology: Adaptation and environment Glenn K. Baggott · Journal of Arid Environments | May 1985 | 1,111 |
| 15 | Pain measurement: an overview C. Richard Chapman, K. L. Casey, Ronald A. Dubner et al. · Pain | May 1985 | 1,095 |
| 16 | Blood sample collection in small laboratory animals Subramani Parasuraman, Ramasamy Raveendran, Kesavan Ramasamy · Journal of Pharmacology and Pharmacotherapeutics | 10 Nov 2010 | 1,081 |
| 17 | Administration of substances to laboratory animals: routes of administration and factors to consider. Patricia V. Turner, Thea Brabb, Cynthia A. Pekow et al. · PubMed | Sep 2011 | 991 |
| 18 | Nitric oxide (NO) and nociceptive processing in the spinal cord Stephen T. Meller, G. F. Gebhart · Pain | Feb 1993 | 953 |
| 19 | α2-Adrenergic Agonists for Regional Anesthesia James C. Eisenach, Marc De Kock, Walter Klimscha · Anesthesiology | Sep 1996 | 913 |
| 20 | The Rat Grimace Scale: A Partially Automated Method for Quantifying Pain in the Laboratory Rat via Facial Expressions Susana G Sotocina, Robert E. Sorge, Austin Zaloum et al. · Molecular Pain | 2011 | 903 |
| 21 | Clinical Pharmacokinetics and Pharmacodynamics of Propofol Marko Sahinovic, Michel M. R. F. Struys, Anthony Ray Absalom · Clinical Pharmacokinetics | 18 Jul 2018 | 843 |
| 22 | A perceptual-defensive-recuperative model of fear and pain Robert C. Bolles, Michael S. Fanselow · Behavioral and Brain Sciences | Jun 1980 | 842 |
| 23 | Microdialysis—principles and applications for studies in animals and man Urban Ungerstedt · Journal of Internal Medicine | Oct 1991 | 821 |
| 24 | Clinical pharmacology of buprenorphine: Ceiling effects at high doses SHARON L. WALSH, Kenzie L. Preston, Maxine L. Stitzer et al. · Clinical Pharmacology & Therapeutics | May 1994 | 779 |
| 25 | Opioid and Nonopioid Mechanisms of Stress Analgesia James W. Lewis, J. Timothy Cannon, John C. Liebeskind · Science | 9 May 1980 | 749 |
| 26 | Animal models of nociception. D Le Bars, Manuela Gozariu, S W Cadden · PubMed | Dec 2001 | 696 |
| 27 | Laboratory routines cause animal stress. Jonathan Balcombe, Neal D. Barnard, Chad B. Sandusky · PubMed | Nov 2004 | 692 |
| 28 | Pretreatment or Resuscitation with a Lipid Infusion Shifts the Dose-Response to Bupivacaine-induced Asystole in Rats Guy L. Weinberg, Timothy R. VadeBoncouer, Gopal A. Ramaraju et al. · Anesthesiology | Apr 1998 | 668 |
| 29 | Guidelines for the Identification, Evaluation, and Management of Systemic Hypertension in Dogs and Cats Scott Anthony Brown, Clarke E. Atkins, R. Bagley et al. · Journal of Veterinary Internal Medicine | May 2007 | 651 |
| 30 | The Pharmacokinetics of the New Short-acting Opioid Remifentanil (GI87084B) in Healthy Adult Male Volunteers Talmage D. Egan, Harry J. M. Lemmens, Pierre Fiset et al. · Anesthesiology | Nov 1993 | 631 |
| 31 | Remifentanil-induced Postoperative Hyperalgesia and Its Prevention with Small-dose Ketamine Vincent Joly, Philippe Richebé, B. Guignard et al. · Anesthesiology | 27 Jun 2005 | 630 |
| 32 | Sex differences in pain perception Zsuzsanna Wiesenfeld‐Hallin · Gender Medicine | Sep 2005 | 613 |
| 33 | Size is everything – large amounts of information are needed to overcome random effects in estimating direction and magnitude of treatment effects R Andrew Moore, David J. Gavaghan, Martin Richard Tramèr et al. · Pain | Dec 1998 | 603 |
| 34 | ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats Mark J. Acierno, Scott Anthony Brown, Amanda Erickson Coleman et al. · Journal of Veterinary Internal Medicine | 24 Oct 2018 | 601 |
| 35 | Development of the Horse Grimace Scale (HGS) as a Pain Assessment Tool in Horses Undergoing Routine Castration Emanuela Dalla Costa, Michela Minero, Dirk Lebelt et al. · PLoS ONE | 19 Mar 2014 | 600 |
| 36 | Effect of Three Types of Mixed Anesthetic Agents Alternate to Ketamine in Mice Sumiko KAWAI, Yasuhiro Takagi, Shiro Kaneko et al. · EXPERIMENTAL ANIMALS | 2011 | 598 |
| 37 | Long-lasting Hyperalgesia Induced by Fentanyl in Rats Evelyne Célèrier, Cyril Rivat, Yan Jun et al. · Anesthesiology | Feb 2000 | 595 |
| 38 | The formalin test: scoring properties of the first and second phases of the pain response in rats Frances V. Abbott, Keith B.J. Franklin, Reginald Frederick Westbrook · Pain | 1995 | 589 |
| 39 | Pharmacokinetics, Pharmacodynamics, and Rational Opioid Selection Steven L. Shafer, John R. Varvel · Anesthesiology | 1991 | 585 |
| 40 | The risk of death: the Confidential Enquiry into Perioperative Small Animal Fatalities Dave C. Brodbelt, KAREN J. BLISSITT, R. A. Hammond et al. · Veterinary Anaesthesia and Analgesia | 5 May 2008 | 582 |
| 41 | Preliminary Pharmacokinetics and Pharmacodynamics of an Ultra-Short-Acting Opioid Peter S. A. Glass, David T A Hardman, Y Kamiyama et al. · Anesthesia & Analgesia | Nov 1993 | 582 |
| 42 | Effects of Intravenous Dexmedetomidine in Humans Jon P. Belleville, Denham S. Ward, B. C. Bloor et al. · Anesthesiology | Dec 1992 | 564 |
| 43 | Anesthetic Potency (MAC) Is Independent of Forebrain Structures in the Rat Ira Jay Rampil, Peggy Mason, Himanshu Singh · Anesthesiology | Apr 1993 | 548 |
| 44 | Experimental and Clinical Applications of Quantitative Sensory Testing Applied to Skin, Muscles and Viscera Lars Arendt‐Nielsen, David Yarnitsky · Journal of Pain | 20 Apr 2009 | 548 |
| 45 | Double‐blind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy Yadollah Harati, Clifton L. Gooch, Michael Swenson et al. · Neurology | Jun 1998 | 544 |
| 46 | Prostaglandins released by the Spleen Norbert J. Gilmore, John Robert Vane, John H Wyllie · Nature | Jun 1968 | 540 |
| 47 | Exaggerated Anesthetic Requirements in the Preferentially Anesthetized Brain Joseph F. Antognini, Kevin R. Schwartz · Anesthesiology | Dec 1993 | 533 |
| 48 | Tissue distribution of beta 3-adrenergic receptor mRNA in man. Stéphane Krief, Fredrik Lönnqvist, S. Raimbault et al. · Journal of Clinical Investigation | 1993 | 532 |
| 49 | Development of the short-form Glasgow Composite Measure Pain Scale (CMPS-SF) and derivation of an analgesic intervention score Jessica Reid, AM Nolan, J. M. L. Hughes et al. · Animal Welfare | May 2007 | 532 |
| 50 | The confidential enquiry into perioperative equine fatalities (CEPEF): mortality results of Phases 1 and 2 G Mark Johnston, J. K. Eastment, JLN Wood et al. · Veterinary Anaesthesia and Analgesia | Oct 2002 | 526 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.