Most cited papers in Vitamin C and Antioxidants Research
What are the most cited papers in Vitamin C and Antioxidants Research?
The most cited paper in Vitamin C and Antioxidants Research is "Free radicals in biology and medicine" (J. M. C. Gutteridge, 1991), with 17,218 citations. Next come "Vitamin D Deficiency" (13,754) and "Oxidants, antioxidants, and the degenerative diseases of aging." (5,991).
Showing 50 of 100 papers. Every paper with more than 1,583 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Free radicals in biology and medicine J. M. C. Gutteridge · General Pharmacology The Vascular System | 1991 | 17,218 |
| 2 | Vitamin D Deficiency Michael F. Holick · New England Journal of Medicine | 18 Jul 2007 | 13,754 |
| 3 | Oxidants, antioxidants, and the degenerative diseases of aging. B N Ames, Mark K. Shigenaga, Tory M. Hagen · Proceedings of the National Academy of Sciences | Sep 1993 | 5,991 |
| 4 | Oxygen-Derived Free Radicals in Postischemic Tissue Injury Franklin H. Epstein, Joe M. McCord · New England Journal of Medicine | 17 Jan 1985 | 5,459 |
| 5 | Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury. Changmeng Cui, Jianzhong Cui, Feng Jin et al. · PubMed | 2017 | 5,190 |
| 6 | Oxidative Stress and Antioxidant Defense Esra Birben, Ümit Murat Şahiner, Cansın Saçkesen et al. · World Allergy Organization Journal | 2012 | 4,985 |
| 7 | Role of Nrf2 in Oxidative Stress and Toxicity Qiang Ma · The Annual Review of Pharmacology and Toxicology | 6 Jan 2013 | 4,940 |
| 8 | Oxidative Stress: Harms and Benefits for Human Health Gabriele Pizzino, Natasha Irrera, Mariapaola Cucinotta et al. · Oxidative Medicine and Cellular Longevity | 2017 | 4,835 |
| 9 | Oxyl radicals, redox-sensitive signalling cascades and antioxidants Marcelo Genestra · Cellular Signalling | 2 May 2007 | 4,791 |
| 10 | Oxidative stress: oxidants and antioxidants Helmut Sies · Experimental Physiology | Mar 1997 | 4,576 |
| 11 | The Pathophysiology and Treatment of Sepsis Richard S. Hotchkiss, Irene E. Karl · New England Journal of Medicine | 8 Jan 2003 | 4,137 |
| 12 | Oxidative stress, aging, and diseases Ilaria Liguori, Gennaro Russo, Francesco Curcio et al. · Clinical Interventions in Aging | Apr 2018 | 4,013 |
| 13 | First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid Osasenaga Macdonald. Ighodaro, Oluseyi Adeboye Akinloye · Alexandria Journal of Medicine | 13 Nov 2017 | 3,970 |
| 14 | [2] Ferric reducing/antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration Iris F. F. Benzie, JJ Strain · Methods in enzymology on CD-ROM/Methods in enzymology | 1999 | 3,940 |
| 15 | The Free Radical Theory of Aging Matures Kenneth B. Beckman, Bruce N. Ames · Physiological Reviews | Apr 1998 | 3,892 |
| 16 | ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis Benoît D’Autréaux, Michel B. Tolédano · Nature Reviews Molecular Cell Biology | 12 Sep 2007 | 3,648 |
| 17 | Bcl-2 functions in an antioxidant pathway to prevent apoptosis David M. Hockenbery, Zoltán N. Oltvai, Xiao-Ming Yin et al. · Cell | Oct 1993 | 3,450 |
| 18 | Protein Oxidation in Aging, Disease, and Oxidative Stress Barbara S. Berlett, Earl R. Stadtman · Journal of Biological Chemistry | Aug 1997 | 3,338 |
| 19 | Advances in metal-induced oxidative stress and human disease Klaudia Jomová, Marián Valko · Toxicology | 16 Mar 2011 | 3,223 |
| 20 | Mitochondrial free radical generation, oxidative stress, and aging Enrique Cadenas, Kelvin J.A. Davies · Free Radical Biology and Medicine | Aug 2000 | 3,002 |
| 21 | Dietary Carcinogens and Anticarcinogens Bruce N. Ames · Science | 23 Sep 1983 | 2,987 |
| 22 | Reactive Oxygen Species and the Central Nervous System Barry B. Halliwell · Journal of Neurochemistry | Nov 1992 | 2,956 |
| 23 | Free radicals, antioxidants, and human disease: curiosity, cause, or consequence? Barry B. Halliwell · The Lancet | Sep 1994 | 2,956 |
| 24 | Biological Defense Mechanisms. THE PRODUCTION BY LEUKOCYTES OF SUPEROXIDE, A POTENTIAL BACTERICIDAL AGENT Bernard M. BABIOR, Ruby S. Kipnes, John T. Curnutte · Journal of Clinical Investigation | Mar 1973 | 2,944 |
| 25 | A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation Özcan Erel · Clinical Biochemistry | 6 Mar 2004 | 2,933 |
| 26 | The acute phase response Heinz Baumann, Jack Gauldie · Immunology Today | Feb 1994 | 2,922 |
| 27 | Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases Phaniendra Alugoju, Dinesh Babu Jestadi, Latha Periyasamy · Indian Journal of Clinical Biochemistry | 14 Jul 2014 | 2,908 |
| 28 | Targeting oxidative stress in disease: promise and limitations of antioxidant therapy Henry Jay Forman, Hongqiao Zhang · Nature Reviews Drug Discovery | 30 Jun 2021 | 2,901 |
| 29 | Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. Aihao H. Ding, Carl Nathan, Dennis J. Stuehr · The Journal of Immunology | Oct 1988 | 2,847 |
| 30 | Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease Michael F. Holick · American Journal of Clinical Nutrition | Dec 2004 | 2,778 |
| 31 | Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy Richard S. Hotchkiss, Guillaume Monneret, Didier M. Payen · Nature reviews. Immunology | 15 Nov 2013 | 2,777 |
| 32 | Action of Phenolic Derivatives (Acetaminophen, Salicylate, and 5-Aminosalicylate) as Inhibitors of Membrane Lipid Peroxidation and as Peroxyl Radical Scavengers Teresa C.P. Dinis, Vı́tor M.C. Madeira, Leonor M. Almeida · Archives of Biochemistry and Biophysics | Nov 1994 | 2,727 |
| 33 | Vitamin D deficiency: a worldwide problem with health consequences Michael F. Holick, Tai C. Chen · American Journal of Clinical Nutrition | Apr 2008 | 2,698 |
| 34 | Role of oxidized low density lipoprotein in atherogenesis. Joseph Lee Witztum, Daniel Howard Steinberg · Journal of Clinical Investigation | Dec 1991 | 2,681 |
| 35 | Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse Mary E. Brunkow, Eric W. Jeffery, Kathryn A. Hjerrild et al. · Nature Genetics | 2001 | 2,636 |
| 36 | Role of Oxidative Modifications in Atherosclerosis Roland Stocker, John F. Keaney · Physiological Reviews | 21 Sep 2004 | 2,618 |
| 37 | Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality Edgar R. Miller, Roberto Pastor‐Barriuso, Darshan Dalal et al. · Annals of Internal Medicine | 4 Jan 2005 | 2,578 |
| 38 | Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging Klaudia Jomová, Renáta Raptová, Suliman Yousef Alomar et al. · Archives of Toxicology | 19 Aug 2023 | 2,548 |
| 39 | Ascorbate and Glutathione: The Heart of the Redox Hub Christine Helen Foyer, Graham Noctor · PLANT PHYSIOLOGY | 2011 | 2,511 |
| 40 | Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases Asima Bhattacharyya, Ranajoy Chattopadhyay, SANKAR P. MITRA et al. · Physiological Reviews | Apr 2014 | 2,498 |
| 41 | The Pecking Order of Free Radicals and Antioxidants: Lipid Peroxidation, α-Tocopherol, and Ascorbate Garry R. Buettner · Archives of Biochemistry and Biophysics | Feb 1993 | 2,414 |
| 42 | Reactive Species and Antioxidants. Redox Biology Is a Fundamental Theme of Aerobic Life Barry B. Halliwell · PLANT PHYSIOLOGY | Jun 2006 | 2,396 |
| 43 | Protein carbonyl groups as biomarkers of oxidative stress Isabella Dalle‐Donne, Ranieri Rossi, Daniela Giustarini et al. · Clinica Chimica Acta | 17 Feb 2003 | 2,366 |
| 44 | Vitamin E Consumption and the Risk of Coronary Heart Disease in Men Eric B. Rimm, Meir J. Stampfer, Alberto Ascherio et al. · New England Journal of Medicine | 20 May 1993 | 2,365 |
| 45 | Lipid peroxidation: its mechanism, measurement, and significance Barry B. Halliwell, S Chirico · American Journal of Clinical Nutrition | May 1993 | 2,361 |
| 46 | Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader11Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee by the United States Department of Agriculture and does not imply its approval to the exclusion of other products that may be suitable. Hong Wang, James A. Joseph · Free Radical Biology and Medicine | Sep 1999 | 2,347 |
| 47 | Signal transduction by reactive oxygen species Toren Finkel · The Journal of Cell Biology | 11 Jul 2011 | 2,331 |
| 48 | Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention Goran Bjelaković, Dimitrinka Nikolova, Lise Lotte Gluud et al. · JAMA | 27 Feb 2007 | 2,276 |
| 49 | Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Jia Liu, Ruiyuan Cao, Mingyue Xu et al. · Cell Discovery | 17 Mar 2020 | 2,191 |
| 50 | The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state Ergül Belge Kurutaş · Nutrition Journal | Dec 2015 | 2,182 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.