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Most cited papers in Wound Healing and Treatments

What are the most cited papers in Wound Healing and Treatments?

The most cited paper in Wound Healing and Treatments is "Re-epithelialization and immune cell behaviour in an ex vivo human skin model" (Ana Rakita, Nenad Nikolić, Michael Mildner et al., 2020), with 8,298 citations. Next come "Wound repair and regeneration" (6,500) and "Cutaneous Wound Healing" (6,150).

Showing 50 of 99 papers. Every paper with more than 1,186 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Re-epithelialization and immune cell behaviour in an ex vivo human skin model Ana Rakita, Nenad Nikolić, Michael Mildner et al. · Scientific Reports Open access 8 Jan 2020 8,298
2 Wound repair and regeneration Geoffrey C. Gurtner, Sabine Werner, Yann Barrandon et al. · Nature Open access 14 May 2008 6,500
3 Cutaneous Wound Healing Adam J. Singer, Richard A.F. Clark · New England Journal of Medicine 2 Sep 1999 6,150
4 Factors Affecting Wound Healing Shuzhen Guo, Luisa Ann DiPietro · Journal of Dental Research Open access 5 Feb 2010 5,767
5 Wound Healing--Aiming for Perfect Skin Regeneration Paul B. Martin · Science 4 Apr 1997 4,845
6 Macrophages in Tissue Repair, Regeneration, and Fibrosis Thomas A. Wynn, Kevin M. Vannella · Immunity Open access Mar 2016 4,536
7 Diabetic Foot Ulcers and Their Recurrence David G. Armstrong, Andrew J.M. Boulton, Sicco A. Bus · New England Journal of Medicine Open access 14 Jun 2017 4,367
8 Myofibroblasts and mechano-regulation of connective tissue remodelling James J. Tomasek, Giulio Gabbiani, Boris Hinz et al. · Nature Reviews Molecular Cell Biology Review May 2002 4,302
9 Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. Petra Boukamp, R T Petrussevska, Dirk Breitkreutz et al. · The Journal of Cell Biology Open access Mar 1988 4,196
10 Regulation of Wound Healing by Growth Factors and Cytokines Sabine Werner, Richard Philip Grose · Physiological Reviews Review Jul 2003 3,647
11 PERSPECTIVE ARTICLE: Growth factors and cytokines in wound healing Stephan Barrientos, Olivera Stojadinović, Michael Samuel Golinko et al. · Wound Repair and Regeneration Sep 2008 3,599
12 Wound repair and regeneration: Mechanisms, signaling, and translation Sabine Anne Eming, Paul B. Martin, Marjana Tomic‐Canic · Science Translational Medicine Open access 3 Dec 2014 3,566
13 Preventing Foot Ulcers in Patients With Diabetes Nalini K. Singh · JAMA 11 Jan 2005 3,130
14 Functional Hydrogels as Wound Dressing to Enhance Wound Healing Yongping Liang, Jiahui He, Baolin Guo · ACS Nano 10 Aug 2021 3,102
15 Wound Healing Dressings and Drug Delivery Systems: A Review Joshua Siaw Boateng, Kerr H. Matthews, Howard N.E. Stevens et al. · Journal of Pharmaceutical Sciences 26 Oct 2007 3,050
16 Wound Healing: A Cellular Perspective Mélanie Rodrigues, Nina Kosaric, Clark Andrew Bonham et al. · Physiological Reviews ReviewOpen access 26 Nov 2018 3,046
17 Human skin wounds: A major and snowballing threat to public health and the economy Chandan K. Sen, Gayle M. Gordillo, Sashwati Roy et al. · Wound Repair and Regeneration Open access 29 Oct 2009 3,003
18 Challenges in the Treatment of Chronic Wounds Robert G. Frykberg, Jaminelli Banks · Advances in Wound Care Open access 17 Jul 2015 2,669
19 Wound healing and its impairment in the diabetic foot Vincent Falanga · The Lancet Nov 2005 2,653
20 The global burden of diabetic foot disease Andrew J.M. Boulton, Loretta Vileikytė, Gunnel Ragnarson-Tennvall et al. · The Lancet Nov 2005 2,580
21 The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms Tomaž Velnar, T. A. Bailey, Vladimir Smrkolj · Journal of International Medical Research Oct 2009 2,452
22 Inflammation in Wound Repair: Molecular and Cellular Mechanisms Sabine Anne Eming, Thomas Krieg, Jeffrey M. Davidson · Journal of Investigative Dermatology Open access 14 Feb 2007 2,438
23 Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts Alexis Desmoulière, Antoine Geinoz, F Gabbiani et al. · The Journal of Cell Biology Open access Jul 1993 2,257
24 Vacuum-Assisted Closure: A New Method for Wound Control and Treatment Michael J. Morykwas, Louis C. Argenta, Erica I. Shelton-Brown et al. · Annals of Plastic Surgery Jun 1997 2,247
25 Wound healing: an overview of acute, fibrotic and delayed healing F. Diegelmann Robert · Frontiers in bioscience Open access 2004 2,153
26 Wound Microbiology and Associated Approaches to Wound Management Philip G. Bowler, Brian I. Duerden, David G. Armstrong · Clinical Microbiology Reviews Open access Apr 2001 2,124
27 Chronic Wound Healing: A Review of Current Management and Treatments George Han, Roger I. Ceilley · Advances in Therapy Open access 20 Jan 2017 2,121
28 Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Eugene Bell, Bodil Ivarsson, Charlotte Merrill · Proceedings of the National Academy of Sciences Open access Mar 1979 2,075
29 An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA Marco Demaria, Naoko Ohtani, Sameh A. Youssef et al. · Developmental Cell Open access Dec 2014 2,069
30 Defining the Epithelial Stem Cell Niche in Skin Tudorita Tumbar, Géraldine Guasch, Valentina Greco et al. · Science Open access 15 Dec 2003 2,063
31 Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing Xin Zhao, Hao Wu, Baolin Guo et al. · Biomaterials 11 Jan 2017 1,986
32 The Transcriptional Program in the Response of Human Fibroblasts to Serum Vishwanath R. Iyer, Michael B. Eisen, Douglas T. Ross et al. · Science 1999 1,984
33 Transition from inflammation to proliferation: a critical step during wound healing Ning Xu, Dongqing Li, Mona Ståhle · Cellular and Molecular Life Sciences Open access 14 May 2016 1,982
34 Integrins and other cell adhesion molecules Steven M Albelda, Clayton A. Buck · The FASEB Journal Aug 1990 1,975
35 Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Modes of Tissue Repair—Current Views Donald G. Phinney, Darwin J. Prockop · Stem Cells 27 Sep 2007 1,923
36 Vacuum-Assisted Closure: A New Method for Wound Control and Treatment Louis C. Argenta, Michael J. Morykwas · Annals of Plastic Surgery Jun 1997 1,911
37 Wound Repair and Regeneration J.M. Reinke, Heiko Sorg · European Surgical Research Open access 2012 1,909
38 Burn Wound Infections Deirdre L. Church, Sameer Elsayed, Owen Reid et al. · Clinical Microbiology Reviews Open access Apr 2006 1,885
39 Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis Pengzi Zhang, Jing Lü, Yali Jing et al. · Annals of Medicine ReviewOpen access Sep 2016 1,853
40 Cellular and molecular basis of wound healing in diabetes Harold Brem, Marjana Tomic‐Canic · Journal of Clinical Investigation Open access May 2007 1,828
41 Evidence that fibroblasts derive from epithelium during tissue fibrosis Masayuki Iwano, David Plieth, Theodore M. Danoff et al. · Journal of Clinical Investigation Open access Aug 2002 1,822
42 Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing Jin Qu, Xin Zhao, Yongping Liang et al. · Biomaterials 24 Aug 2018 1,818
43 Wound healing: cellular mechanisms and pathological outcomes Holly Nicola Wilkinson, Matthew James Hardman · Open Biology Open access Sep 2020 1,810
44 Immunomodulatory properties of mesenchymal stromal cells Alma J. Nauta, Willem E. Fibbe · Blood Open access 30 Jul 2007 1,805
45 The Timing of Prophylactic Administration of Antibiotics and the Risk of Surgical-Wound Infection David C. Classen, R. Scott Evans, Stanley L. Pestotnik et al. · New England Journal of Medicine 30 Jan 1992 1,766
46 Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis Yaojiong Wu, Liwen Chen, Paul G. Scott et al. · Stem Cells 5 Jul 2007 1,713
47 The Society for Vascular Surgery Lower Extremity Threatened Limb Classification System: Risk stratification based on Wound, Ischemia, and foot Infection (WIfI) Joseph L. Mills, Michael S. Conte, David G. Armstrong et al. · Journal of Vascular Surgery Open access 12 Oct 2013 1,706
48 A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings Elbadawy A. Kamoun, El-Refaie S. Kenawy, Xin Chen · Journal of Advanced Research Open access 4 Feb 2017 1,704
49 Inflammation and wound healing: the role of the macrophage Timothy Jon Koh, Luisa Ann DiPietro · Expert Reviews in Molecular Medicine Open access Jul 2011 1,672
50 Burn injury Marc G. Jeschke, Margriet E. van Baar, Mashkoor A. Choudhry et al. · Nature Reviews Disease Primers ReviewOpen access 13 Feb 2020 1,665

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.