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Most cited papers in Dentistry

What are the most cited papers in Dentistry?

The most cited paper in Dentistry is "APACHE II-A Severity of Disease Classification System" (William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al., 1986), with 13,426 citations. Next come "Bacterial Biofilms: A Common Cause of Persistent Infections" (12,236) and "The biofilm matrix" (10,070).

Showing 50 of 100 papers. Every paper with more than 1,789 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 APACHE II-A Severity of Disease Classification System William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine Aug 1986 13,426
2 Bacterial Biofilms: A Common Cause of Persistent Infections John William Costerton, Philip Shook Stewart, Everett Peter Greenberg · Science 21 May 1999 12,236
3 The biofilm matrix Hans‐Curt Flemming, Jost Wingender · Nature Reviews Microbiology Review 2 Aug 2010 10,070
4 Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal Condition John Silness, Harald A. Löe · Acta Odontologica Scandinavica Open access 1964 7,977
5 Periodontal Disease in Pregnancy I. Prevalence and Severity Harald A. Löe, John Silness · Acta Odontologica Scandinavica Open access 1963 7,274
6 Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms Rodney M. Donlan, John William Costerton · Clinical Microbiology Reviews Open access Apr 2002 6,669
7 Porosity of 3D biomaterial scaffolds and osteogenesis Vassilis Karageorgiou, David Lee Kaplan · Biomaterials 9 Apr 2005 6,635
8 Low Health Literacy and Health Outcomes: An Updated Systematic Review Nancy D Berkman, Stacey Sheridan, Katrina E Donahue et al. · Annals of Internal Medicine Review 19 Jul 2011 5,609
9 Development of a Classification System for Periodontal Diseases and Conditions Gary C. Armitage · Annals of Periodontology Open access Dec 1999 5,147
10 Microbial complexes in subgingival plaque S. S. Socransky, A. D. Haffajee, MaryAnn Cugini et al. · Journal Of Clinical Periodontology Feb 1998 5,112
11 Bioceramics: From Concept to Clinic Larry L. Hench · Journal of the American Ceramic Society Jul 1991 4,972
12 Biofilms: Microbial Life on Surfaces Rodney M. Donlan · Emerging infectious diseases Open access Sep 2002 4,917
13 A 15-year study of osseointegrated implants in the treatment of the edentulous jaw Ragnar Adell, Ulf Lekholm, Birger Rockler et al. · International Journal of Oral Surgery 1981 4,839
14 Antibiotic resistance of bacteria in biofilms Philip Shook Stewart, John William Costerton · The Lancet Jul 2001 4,602
15 Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network* and Orofacial Pain Special Interest Group† ERIC L. SCHIFFMAN et al. · Journal of Oral & Facial Pain and Headache Open access 2014 4,547
16 Proteobacteria: microbial signature of dysbiosis in gut microbiota Na-Ri Shin, Tae Woong Whon, Jin‐Woo Bae · Trends in biotechnology Review 22 Jul 2015 4,155
17 Oral diseases: a global public health challenge Marco Aurélio Peres, Lorna M. D. Macpherson, Robert J. Weyant et al. · The Lancet Open access Jul 2019 3,955
18 Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Günter Kampf, Daniel Tödt, Stephanie Pfaender et al. · Journal of Hospital Infection Open access 6 Feb 2020 3,919
19 Solutions able to reproduce in vivo surface‐structure changes in bioactive glass‐ceramic A‐W 3 T Kokubo, H. Kushitani, S. Sakka et al. · Journal of Biomedical Materials Research Jun 1990 3,844
20 Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. Samuel F. Dworkin, Linda LeResche · PubMed 1992 3,828
21 Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer Jan B. Vermorken, Ricard Mesı́a, Fernando Rivera et al. · New England Journal of Medicine Open access 10 Sep 2008 3,762
22 Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data Nicole M. Davis, Diana M. Proctor, Susan Holmes et al. · Microbiome Open access Dec 2018 3,699
23 “Field cancerization” in oral stratified squamous epithelium. Clinical implications of multicentric origin Danely P. Slaughter, Harry W. Southwick, Walter Smejkal · Cancer Open access Sep 1953 3,563
24 Periodontal diseases Bruce Lee Pihlstrom, Bryan S. Michalowicz, Newell Walter Johnson · The Lancet Nov 2005 3,559
25 Experimental Gingivitis in Man Harald A. Löe, Else Theilade, S. Børglum Jensen · Journal of Periodontology May 1965 3,510
26 Global epidemiology of oral and oropharyngeal cancer Saman Warnakulasuriya · Oral Oncology 19 Sep 2008 3,484
27 Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Kelvin Kai‐Wang To et al. · The Lancet Infectious Diseases Open access 23 Mar 2020 3,383
28 The Human Oral Microbiome Floyd E. Dewhirst, Tuste Chen, Jacques Izard et al. · Journal of Bacteriology Open access 23 Jul 2010 3,327
29 A taxonomic note on the genus Lactobacillus: Description of 23 novel genera, emended description of the genus Lactobacillus Beijerinck 1901, and union of Lactobacillaceae and Leuconostocaceae Jinshui Zheng, Stijn Wittouck, Elisa Salvetti et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY Open access Apr 2020 3,325
30 Microbiome Datasets Are Compositional: And This Is Not Optional Gregory Brian Gloor, Jean M. Macklaim, Vera Pawlowsky‐Glahn et al. · Frontiers in Microbiology Open access 15 Nov 2017 3,290
31 Antibiotic resistance of bacterial biofilms Niels Høiby, Thomas Bjarnsholt, Michael Givskov et al. · International Journal of Antimicrobial Agents 11 Feb 2010 3,283
32 Staging and grading of periodontitis: Framework and proposal of a new classification and case definition Maurizio S. Tonetti, Henry Greenwell, Kenneth S. Kornman · Journal of Periodontology Open access Jun 2018 3,251
33 Bonding mechanisms at the interface of ceramic prosthetic materials Larry L. Hench, R. J. Splinter, William C. Allen et al. · Journal of Biomedical Materials Research Nov 1971 3,245
34 The World Oral Health Report 2003: continuous improvement of oral health in the 21st century – the approach of the WHO Global Oral Health Programme Poul Erik Petersen · Community Dentistry And Oral Epidemiology 21 Nov 2003 3,219
35 Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions Panos N. Papapanou et al. · Journal of Periodontology Open access Jun 2018 3,213
36 Defining the Normal Bacterial Flora of the Oral Cavity Jørn A. Aas, Bruce J. Paster, Lauren N. Stokes et al. · Journal of Clinical Microbiology Open access Nov 2005 3,138
37 Periodontitis: from microbial immune subversion to systemic inflammation George Hajishengallis · Nature reviews. Immunology ReviewOpen access 23 Dec 2014 3,055
38 Matrix Metalloproteinases: A Review Henning Birkedal‐Hansen, William G. I. Moore, Malena Bodden et al. · Critical Reviews in Oral Biology & Medicine 1993 2,995
39 Improved Survival of Patients With Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma in a Prospective Clinical Trial Carole Fakhry, William H. Westra, S. Li et al. · JNCI Journal of the National Cancer Institute 12 Feb 2008 2,814
40 Understanding biofilm resistance to antibacterial agents David G. Davies · Nature Reviews Drug Discovery Review 31 Jan 2003 2,810
41 Derivation and validation of a short‐form oral health impact profile Gary Douglas Slade · Community Dentistry And Oral Epidemiology Aug 1997 2,753
42 Case–Control Study of Human Papillomavirus and Oropharyngeal Cancer Gypsyamber DʼSouza, Aimée R. Kreimer, Raphael P. Viscidi et al. · New England Journal of Medicine 9 May 2007 2,706
43 Osseointegrated Titanium Implants: Requirements for Ensuring a Long-Lasting, Direct Bone-to-Implant Anchorage in Man Tomas O. Albrektsson, Per‐Ingvar Brånemark, Hans‐Arne Hansson et al. · Acta Orthopaedica Scandinavica 1981 2,698
44 Dental caries Robert H. Selwitz, Amid Ibrahim Ismail, Nigel Berry Pitts · The Lancet 2007 2,667
45 The Simplified Oral Hygiene Index John Gerald Greene, Jack R. Vermillion · The Journal of the American Dental Association 1964 2,662
46 The global burden of oral diseases and risks to oral health. Poul Erik Petersen, Denis M. Bourgeois, Hiroshi Ogawa et al. · PubMed Open access Sep 2005 2,660
47 Bioceramics Larry L. Hench · Journal of the American Ceramic Society Jul 1998 2,649
48 Periodontal diseases Denis F. Kinane, Panagiota G. Stathopoulou, Panos N. Papapanou · Nature Reviews Disease Primers Review 22 Jun 2017 2,638
49 A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics Alexander Hoppe, Nusret Sena Güldal, Aldo Roberto Boccaccini · Biomaterials 3 Feb 2011 2,613
50 Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee David W. Dempster, Juliet Elizabeth Compston, Marc K. Drezner et al. · Journal of Bone and Mineral Research Open access 29 Nov 2012 2,599

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.