| 1 |
Cyclin D1 is a nuclear protein required for cell cycle progression in G1.
Véronique Baldin, Jiří Lukáš, María Jesús Marcote et al. · Genes & Development
Open access |
May 1993 |
1,638 |
| 2 |
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
Massimo F. Loda, Barry Cukor, Sun W. Tam et al. · Nature Medicine
|
Feb 1997 |
1,050 |
| 3 |
CDC25 Phosphatases as Potential Human Oncogenes
Konstantin I. Galaktionov, Arthur K. Lee, Jens W. Eckstein et al. · Science
|
15 Sep 1995 |
506 |
| 4 |
CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors
Linchun Jin, Haipeng Tao, Aida Karachi et al. · Nature Communications
Open access |
5 Sep 2019 |
376 |
| 5 |
Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.
Michele Pagano, Rainer Pepperkok, Jiří Lukáš et al. · The Journal of Cell Biology
Open access |
Apr 1993 |
325 |
| 6 |
Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts.
Michele Pagano, A M Theodoras, See‐Ying Tam et al. · Genes & Development
Open access |
15 Jul 1994 |
296 |
| 7 |
Differential expression and regulation of Cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for Cyclin D1 function in G1 progression.
Sun W. Tam, Anne M. Theodoras, Jerry W. Shay et al. · PubMed
|
Sep 1994 |
274 |
| 8 |
LocoMMotion: a prospective, non-interventional, multinational study of real-life current standards of care in patients with relapsed and/or refractory multiple myeloma
María‐Victoria Mateos et al. · Leukemia
Open access |
24 Mar 2022 |
251 |
| 9 |
Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis
Chelin Jamie Hu, Marcus A. Garcia, Alexander J. Nihart et al. · Toxicological Sciences
Open access |
3 May 2024 |
233 |
| 10 |
Streptococcal co‐infection augments C andida pathogenicity by amplifying the mucosal inflammatory response
Hongbin Xu, Takanori Sobue, Angela Knight Thompson et al. · Cellular Microbiology
Open access |
Oct 2013 |
182 |
| 11 |
ELISA HTLV RETROVIRUS ANTIBODY REACTIVITY ASSOCIATED WITH MALARIA AND IMMUNE COMPLEXES IN HEALTHY AFRICANS
Robert J. Biggar · The Lancet
|
Sep 1985 |
164 |
| 12 |
MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors
Ali Kinkhabwala et al. · Scientific Reports
Open access |
3 Feb 2022 |
152 |
| 13 |
Cdc25 protein phosphatases in cell proliferation
Giulio Francesco Draetta, Jens W. Eckstein · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
|
Apr 1997 |
148 |
| 14 |
Final Results of the RHAPSODY Trial: A Multi‐Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A‐APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke
Patrick D. Lyden et al. · Annals of Neurology
Open access |
19 Nov 2018 |
146 |
| 15 |
Simple Isoquinoline and Benzylisoquinoline Alkaloids as Potential Antimicrobial, Antimalarial, Cytotoxic, and Anti-HIV Agents
Kinuko Iwasa, Masataka Moriyasu, Yoko Tachibana et al. · Bioorganic & Medicinal Chemistry
|
Nov 2001 |
129 |
| 16 |
Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States
Yuan Chun Ding, Linda Roslyn Steele, Chih-Jen Kuan et al. · Breast Cancer Research and Treatment
Open access |
6 Oct 2010 |
126 |
| 17 |
Long-Term (≥5-Year) Remission and Survival After Treatment With Ciltacabtagene Autoleucel in CARTITUDE-1 Patients With Relapsed/Refractory Multiple Myeloma
Sundar Jagannath et al. · Journal of Clinical Oncology
Open access |
3 Jun 2025 |
122 |
| 18 |
DNA Banking for Epidemiologic Studies: A Review of Current Practices
KAREN K. STEINBERG, Jeanne C. Beck, Deborah A. Nickerson et al. · Epidemiology
|
May 2002 |
121 |
| 19 |
Cabozantinib-based combination therapy for the treatment of hepatocellular carcinoma
Runze Shang, Xinhua Song, Pan Wang et al. · Gut
Open access |
3 Nov 2020 |
107 |
| 20 |
Coral transcriptome and bacterial community profiles reveal distinct Yellow Band Disease states inOrbicella faveolata
Collin J. Closek, Shinichi Sunagawa, Michael K. DeSalvo et al. · The ISME Journal
Open access |
20 Jun 2014 |
93 |
| 21 |
Interaction between Cdc37 and Cdk4 in human cells
Lou Lamphere, Francesca Fiore, Xu Xu et al. · Oncogene
|
24 Apr 1997 |
92 |
| 22 |
Karyotype Heterogeneity and Unclassified Chromosomal Abnormalities
Henry H. Heng, Guiming Liu, Joshua B. Stevens et al. · Cytogenetic and Genome Research
|
2013 |
91 |
| 23 |
Clonal and non-clonal chromosome aberrations and genome variation and aberration
Henry H. Heng, Guo Liu, Steven W. Bremer et al. · Genome
|
Mar 2006 |
88 |
| 24 |
Variation in human T lymphotropic virus III (HTLV-III) antibodies in homosexual men: decline before onset of illness related to acquired immune deficiency syndrome (AIDS).
Robert J. Biggar, Mads Melbye, Peter Ebbesen et al. · BMJ
Open access |
12 Oct 1985 |
88 |
| 25 |
The Expanding Toolbox of In Vivo Bioluminescent Imaging
Tingting Xu, Dan M. Close, Winode Handagama et al. · Frontiers in Oncology
Open access |
23 Jun 2016 |
87 |
| 26 |
Anti-drug Antibody Validation Testing and Reporting Harmonization
Heather A. Myler et al. · The AAPS Journal
Open access |
Dec 2021 |
80 |
| 27 |
Expression of a Humanized Viral 2A-Mediated lux Operon Efficiently Generates Autonomous Bioluminescence in Human Cells
Tingting Xu, Steven A. Ripp, Gary S. Sayler et al. · PLoS ONE
Open access |
2 May 2014 |
80 |
| 28 |
Antimicrobial effect of silver-impregnated cellulose: potential for antimicrobial therapy
Ju‐Young Kim, Soonjo Kwon, Erik Ostler · Journal of Biological Engineering
Open access |
Dec 2009 |
77 |
| 29 |
Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells
Marco Künzli, Stephen D. O’Flanagan, Madeleine LaRue et al. · Science Immunology
Open access |
2 Dec 2022 |
76 |
| 30 |
Lysinibacillus spp.: an IAA-producing endospore forming-bacteria that promotes plant growth
Manuel Pantoja-Guerra, Marleny Burkett-Cadena, Johanna Cadena et al. · Antonie van Leeuwenhoek
Open access |
3 May 2023 |
73 |
| 31 |
Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits
David W. Pate, KRISTIINA JÄRVINEN, Arto O. Urtti et al. · Life Sciences
|
Nov 1998 |
73 |
| 32 |
An Activated Protein C Analog With Reduced Anticoagulant Activity Extends the Therapeutic Window of Tissue Plasminogen Activator for Ischemic Stroke in Rodents
Yaoming Wang, Zhenggang Zhang, Nienwen Chow et al. · Stroke
Open access |
18 Jul 2012 |
65 |
| 33 |
Effects of topical anandamides on intraocular pressure in normotensive rabbits
David W. Pate, Kristiina Järvinen, Arto O. Urtti et al. · Life Sciences
|
Apr 1996 |
65 |
| 34 |
A randomized phase II pilot trial of adjuvant marimastat in patients with early-stage breast cancer
Kathy D. Miller, William John Gradishar, Lynn Mara Schuchter et al. · Annals of Oncology
Open access |
Aug 2002 |
64 |
| 35 |
CAR+ T-Cell Lymphoma after Cilta-cel Therapy for Relapsed or Refractory Myeloma
Simon James Harrison et al. · New England Journal of Medicine
|
12 Feb 2025 |
60 |
| 36 |
Effect of linker variation on the stability, potency, and efficacy of carcinoma-reactive BR64-doxorubicin immunoconjugates.
Pamela A. Trail, David Willner, Jay O. Knipe et al. · PubMed
|
1997 |
56 |
| 37 |
Soil heavy metal contamination in residential neighborhoods in post-industrial cities and its potential human exposure risk
Kuhuk Sharma, Nicholas Thomas Basta, Parwinder S. Grewal · Urban Ecosystems
|
11 Aug 2014 |
55 |
| 38 |
Hemofiltration Successfully Eliminates Severe Cytokine Release Syndrome Following CD19 CAR-T-Cell Therapy
Yanfen Liu, Xinfeng Chen, Dao Wang et al. · Journal of Immunotherapy
Open access |
7 Sep 2018 |
53 |
| 39 |
Fatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance
Lei Hong, Yang Sun, Zhu‐Min Luo et al. · Scientific Reports
Open access |
7 Jan 2016 |
53 |
| 40 |
Differential Neuroprotection and Risk for Bleeding From Activated Protein C With Varying Degrees of Anticoagulant Activity
Yaoming Wang, Meenakshisundaram Thiyagarajan, Nienwen Chow et al. · Stroke
Open access |
5 Dec 2008 |
52 |
| 41 |
Action of xylan deacetylating enzymes on monoacetyl derivatives of 4-nitrophenyl glycosides of β-d-xylopyranose and α-l-arabinofuranose
Peter Biely, Mária Mastihubová, Maija Tenkanen et al. · Journal of Biotechnology
Open access |
27 Oct 2010 |
50 |
| 42 |
Ceria Nanoparticles Fabricated with 6‐Aminohexanoic Acid that Overcome Systemic Inflammatory Response Syndrome
Han‐Gil Jeong, Bong Geun Cha, Dong‐Wan Kang et al. · Advanced Healthcare Materials
|
6 Mar 2019 |
47 |
| 43 |
Genetic and Epigenetic Heterogeneity in Cancer: The Ultimate Challenge for Drug Therapy
Henry H. Heng, Geyuan Liu, Joshua B. Stevens et al. · Current Drug Targets
|
Oct 2010 |
44 |
| 44 |
Best Practices for the Development, Scale-up, and Post-approval Change Control of IR and MR Dosage Forms in the Current Quality-by-Design Paradigm
Glenn A. Van Buskirk et al. · AAPS PharmSciTech
Open access |
27 Feb 2014 |
44 |
| 45 |
Cilta-cel in lenalidomide-refractory multiple myeloma (CARTITUDE-4): an updated analysis including overall survival from an open-label, multicentre, randomised, phase 3 trial
Hermann Einsele et al. · The Lancet Oncology
Open access |
7 Jan 2026 |
43 |
| 46 |
Gene profiling identifies genes specific for well-differentiated epithelial thyroid tumors.
Puskás Lg, Ferenc Juhász, A Zarva et al. · PubMed
|
5 Sep 2005 |
39 |
| 47 |
Severe illness associated with appearance of antibody to human immunodeficiency virus in an African.
Robert J. Biggar, Barbara Johnson, S S Musoke et al. · BMJ
Open access |
8 Nov 1986 |
38 |
| 48 |
Heterogeneity of Cell Death
Joshua B. Stevens, Batoul Y. Abdallah, Guiming Liu et al. · Cytogenetic and Genome Research
|
2013 |
37 |
| 49 |
Lab on a chip for multiplexed immunoassays to detect bladder cancer using multifunctional dielectrophoretic manipulations
Cheng‐Hsin Chuang, Tingfeng Wu, Cheng-Ho Chen et al. · Lab on a Chip
|
2015 |
37 |
| 50 |
Culture Conditions and Enzymatic Passaging of Bovine ESC-Like Cells
Guochun Gong, Marsha L. Roach, Le Jiang et al. · Cellular Reprogramming
|
Apr 2010 |
35 |