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Company · Knoxville · United States

490 BioTech (United States)

In research, 490 BioTech (United States) stands highest in Life Sciences (#8,310 of 11,023 worldwide), over all time.

490biotech.comROR OpenAlex
World rank, 2022-now
#20,068
of 22,385 · #26,704 all time
Rank in United States
#2,967
of 3,332
Research works
312
▲ 132% vs 2018-21
Citations
4.5k
14.4 per fractional work
Top-10% rate
11.1%
all institutions 10.0%
vs its own fields
0.98×
1.00× is exactly expected
Open access
42%
world 40%
International
29%
world 18%
490 BioTech (United States)

What is 490 BioTech (United States) known for in research?

The fields where it stands highest, over all time, ranked among every institution above the floor in each field.

FieldWorld rankWhere that sitsTop-10% rateWorks
Life SciencesDomain #8,310 of 11,023 6.9%140

Each strip is that field's whole ranked pool, with the notch where 490 BioTech (United States) sits in it, in the colour of the band that rank falls in. The track under the rate is the rate itself: it carries no average mark, because the average differs by field (from about 6% in Dentistry to 21% in Economics).

Which fields of science does 490 BioTech (United States) work in?

In 2022-now, 40% of research at 490 BioTech (United States) is in Health Sciences, 36% in Life Sciences. Its largest fields are Medicine (37%), Biochemistry, Genetics and Molecular Biology (21%), Engineering (7%). It does 2.5× the world's share of Life Sciences.

Health Sciences: 45 fractional works · 40.3% of its workMedicine: 41 fractional works · 36.9% of its workOncology: 11 fractional works · 9.8% of its workPulmonary and Respiratory Medicine: 3 fractional works · 2.7% of its workRadiology, Nuclear Medicine and Imaging: 3 fractional works · 2.4% of its workHematology: 3 fractional works · 2.3% of its workEpidemiology: 2 fractional works · 2.2% of its workPublic Health, Environmental and Occupational Health: 2 fractional works · 2.2% of its workSurgery: 2 fractional works · 1.9% of its workInfectious Diseases: 2 fractional works · 1.7% of its workComplementary and alternative medicine: 2 fractional works · 1.7% of its workPhysiology: 2 fractional works · 1.5% of its workGenetics: 2 fractional works · 1.5% of its workReproductive Medicine: 1 fractional works · 0.8% of its workPediatrics, Perinatology and Child Health: 1 fractional works · 0.8% of its workCardiology and Cardiovascular Medicine: 1 fractional works · 0.7% of its workRehabilitation: 1 fractional works · 0.6% of its workRheumatology: 1 fractional works · 0.6% of its workNeurology: 1 fractional works · 0.5% of its workPharmacology: 1 fractional works · 0.5% of its workEndocrinology, Diabetes and Metabolism: 0 fractional works · 0.4% of its workDermatology: 0 fractional works · 0.4% of its workCritical Care and Intensive Care Medicine: 0 fractional works · 0.3% of its workPathology and Forensic Medicine: 0 fractional works · 0.3% of its workAnesthesiology and Pain Medicine: 0 fractional works · 0.2% of its workBiochemistry: 0 fractional works · 0.2% of its workSmaller subfields together: 1 fractional works · 0.8% of its workHealth Professions: 2 fractional works · 1.9% of its workEmergency Medical Services: 1 fractional works · 1.0% of its workHealth Information Management: 0 fractional works · 0.3% of its workOccupational Therapy: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.4% of its workNursing: 1 fractional works · 1.2% of its workNutrition and Dietetics: 1 fractional works · 1.2% of its workVeterinary: 0 fractional works · 0.2% of its workDentistry: 0 fractional works · 0.1% of its workLife Sciences: 41 fractional works · 36.3% of its workBiochemistry, Genetics and Molecular Biology: 23 fractional works · 20.8% of its workMolecular Biology: 14 fractional works · 12.2% of its workGenetics: 4 fractional works · 3.6% of its workCell Biology: 2 fractional works · 2.1% of its workCancer Research: 2 fractional works · 1.5% of its workBiotechnology: 1 fractional works · 0.7% of its workBiophysics: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.3% of its workAgricultural and Biological Sciences: 7 fractional works · 6.5% of its workPlant Science: 4 fractional works · 3.5% of its workAgronomy and Crop Science: 1 fractional works · 0.8% of its workFood Science: 1 fractional works · 0.6% of its workGeneral Agricultural and Biological Sciences: 1 fractional works · 0.5% of its workAnimal Science and Zoology: 0 fractional works · 0.4% of its workEcology, Evolution, Behavior and Systematics: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.3% of its workImmunology and Microbiology: 5 fractional works · 4.4% of its workImmunology: 4 fractional works · 4.0% of its workSmaller subfields together: 0 fractional works · 0.4% of its workNeuroscience: 4 fractional works · 3.5% of its workCellular and Molecular Neuroscience: 2 fractional works · 1.9% of its workNeurology: 1 fractional works · 0.5% of its workBehavioral Neuroscience: 0 fractional works · 0.4% of its workCognitive Neuroscience: 0 fractional works · 0.4% of its workSmaller subfields together: 0 fractional works · 0.3% of its workPharmacology, Toxicology and Pharmaceutics: 1 fractional works · 1.2% of its workPharmacology: 1 fractional works · 0.8% of its workPharmaceutical Science: 0 fractional works · 0.2% of its workSmaller subfields together: 0 fractional works · 0.1% of its workPhysical Sciences: 19 fractional works · 17.3% of its workEngineering: 8 fractional works · 7.1% of its workBiomedical Engineering: 4 fractional works · 3.5% of its workElectrical and Electronic Engineering: 1 fractional works · 1.3% of its workMechanical Engineering: 1 fractional works · 0.9% of its workSafety, Risk, Reliability and Quality: 0 fractional works · 0.4% of its workBuilding and Construction: 0 fractional works · 0.3% of its workControl and Systems Engineering: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.3% of its workEnvironmental Science: 4 fractional works · 3.5% of its workHealth, Toxicology and Mutagenesis: 1 fractional works · 1.2% of its workGlobal and Planetary Change: 1 fractional works · 0.7% of its workEcology: 1 fractional works · 0.5% of its workEnvironmental Engineering: 0 fractional works · 0.4% of its workPollution: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.4% of its workComputer Science: 3 fractional works · 2.8% of its workArtificial Intelligence: 2 fractional works · 1.8% of its workComputational Theory and Mathematics: 1 fractional works · 0.5% of its workComputer Vision and Pattern Recognition: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workChemistry: 2 fractional works · 2.0% of its workAnalytical Chemistry: 1 fractional works · 0.6% of its workSpectroscopy: 1 fractional works · 0.5% of its workPhysical and Theoretical Chemistry: 0 fractional works · 0.4% of its workOrganic Chemistry: 0 fractional works · 0.4% of its workMaterials Science: 1 fractional works · 1.0% of its workMaterials Chemistry: 1 fractional works · 0.6% of its workSmaller subfields together: 0 fractional works · 0.3% of its workPhysics and Astronomy: 0 fractional works · 0.4% of its workAstronomy and Astrophysics: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.1% of its workEnergy: 0 fractional works · 0.3% of its workEnergy Engineering and Power Technology: 0 fractional works · 0.3% of its workSmaller subfields together: 0 fractional works · 0.0% of its workEarth and Planetary Sciences: 0 fractional works · 0.3% of its workSocial Sciences: 7 fractional works · 6.1% of its workDecision Sciences: 2 fractional works · 1.8% of its workManagement Science and Operations Research: 1 fractional works · 1.2% of its workInformation Systems and Management: 1 fractional works · 0.6% of its workSocial Sciences: 2 fractional works · 1.5% of its workHealth: 1 fractional works · 0.6% of its workSociology and Political Science: 1 fractional works · 0.6% of its workSafety Research: 0 fractional works · 0.3% of its workEconomics, Econometrics and Finance: 2 fractional works · 1.3% of its workEconomics and Econometrics: 2 fractional works · 1.3% of its workPsychology: 1 fractional works · 1.1% of its workClinical Psychology: 1 fractional works · 0.8% of its workSocial Psychology: 0 fractional works · 0.3% of its workBusiness, Management and Accounting: 0 fractional works · 0.4% of its workStrategy and Management: 0 fractional works · 0.4% of its workALL ITS WORK490 BioTech(United States)112fractional works, 2022-now
Life Sciences36%Physical Sciences17%Health Sciences40%Social Sciences6%

Each ring splits the one inside it: the four domains of science, their fields, their subfields. Size is fractional works in 2022-now. Every slice is a page; the interactive view zooms down to single topics and colours each by how much more of it this institution does than the world.

Its 4 domains and 23 fields, with their numbers
    1. Medicine4136.9%
    2. Health Professions21.9%
    3. Nursing11.2%
    4. Veterinary00.2%
    5. Dentistry00.1%
    1. Biochemistry, Genetics and Molecular Biology2320.8%
    2. Agricultural and Biological Sciences76.5%
    3. Immunology and Microbiology54.4%
    4. Neuroscience43.5%
    5. Pharmacology, Toxicology and Pharmaceutics11.2%
    1. Engineering87.1%
    2. Environmental Science43.5%
    3. Computer Science32.8%
    4. Chemistry22.0%
    5. Materials Science11.0%
    6. Physics and Astronomy00.4%
    7. Energy00.3%
    8. Earth and Planetary Sciences00.3%
    1. Decision Sciences21.8%
    2. Social Sciences21.5%
    3. Economics, Econometrics and Finance21.3%
    4. Psychology11.1%
    5. Business, Management and Accounting00.4%
All of science, and how each field's share has moved since 1950: the Science domain explorer

Field profile

Location quotient across every field it publishes in: outside the ring is more than an institution of this size would be expected to publish, inside it is less.

Agricultural and Biological Sciences: 1.36× its world share, 7 worksAgricultural and Bio…Biochemistry, Genetics and Molecular Biology: 3.90× its world share, 23 worksBiochemistry, Geneti…Immunology and Microbiology: 4.35× its world share, 5 worksImmunology and Micro…Neuroscience: 2.13× its world share, 4 worksNeurosciencePharmacology, Toxicology and Pharmaceutics: 3.45× its world share, 1 worksPharmacology, Toxico…Chemistry: 1.25× its world share, 2 worksChemistryComputer Science: 0.36× its world share, 3 worksComputer ScienceEarth and Planetary Sciences: 0.19× its world share, 0 worksEarth and Planetary …Energy: 0.37× its world share, 0 worksEnergyEngineering: 0.47× its world share, 8 worksEngineeringEnvironmental Science: 0.71× its world share, 4 worksEnvironmental ScienceMaterials Science: 0.27× its world share, 1 worksMaterials SciencePhysics and Astronomy: 0.17× its world share, 0 worksPhysics and AstronomyDentistry: 0.12× its world share, 0 worksDentistryHealth Professions: 0.74× its world share, 2 worksHealth ProfessionsMedicine: 1.92× its world share, 41 worksMedicineNursing: 2.35× its world share, 1 worksNursingVeterinary: 1.42× its world share, 0 worksVeterinaryBusiness, Management and Accounting: 0.11× its world share, 0 worksBusiness, Management…Decision Sciences: 1.85× its world share, 2 worksDecision SciencesEconomics, Econometrics and Finance: 0.63× its world share, 2 worksEconomics, Econometr…Psychology: 0.37× its world share, 1 worksPsychologySocial Sciences: 0.12× its world share, 2 worksSocial Sciences1×world share
more than its size predictsabout as predictedless

Rings at 0.5×, 1× and 2×. Widest outward: Immunology and Microbiology, 4.3×. Every wedge is a field page.

All 23 fields, with their numbers
  1. Immunology and Microbiology4.35×5 works
  2. Biochemistry, Genetics and Molecular Biology3.90×23 works
  3. Pharmacology, Toxicology and Pharmaceutics3.45×1 works
  4. Nursing2.35×1 works
  5. Neuroscience2.13×4 works
  6. Medicine1.92×41 works
  7. Decision Sciences1.85×2 works
  8. Veterinary1.42×0 works
  9. Agricultural and Biological Sciences1.36×7 works
  10. Chemistry1.25×2 works
  11. Health Professions0.74×2 works
  12. Environmental Science0.71×4 works
  13. Economics, Econometrics and Finance0.63×2 works
  14. Engineering0.47×8 works
  15. Energy0.37×0 works
  16. Psychology0.37×1 works
  17. Computer Science0.36×3 works
  18. Materials Science0.27×1 works
  19. Earth and Planetary Sciences0.19×0 works
  20. Physics and Astronomy0.17×0 works
  21. Dentistry0.12×0 works
  22. Social Sciences0.12×2 works
  23. Business, Management and Accounting0.11×0 works

Who are the top researchers at 490 BioTech (United States)?

Ranked on the quality score, Matthew Perciavalle and Taghi Alereza lead among researchers whose main affiliation is 490 BioTech (United States).

  1. 1 Matthew Perciavalle United States · #4,241,742 worldwide 42 citations · 45 works
  2. 2 Taghi Alereza United States · #5,283,809 worldwide 31 citations · 17 works
All ranked researchers at 490 BioTech (United States)

What are the most cited papers from 490 BioTech (United States)?

The most cited paper from 490 BioTech (United States) is "Cyclin D1 is a nuclear protein required for cell cycle progression in G1." (Véronique Baldin, Jiří Lukáš, María Jesús Marcote et al., 1993), with 1,638 citations. Next come "Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas" (1,050) and "CDC25 Phosphatases as Potential Human Oncogenes" (506).

Most cited papers
#PaperReleasedCitations
1 Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Véronique Baldin, Jiří Lukáš, María Jesús Marcote et al. · Genes & Development Open access May 1993 1,638
2 Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas Massimo F. Loda, Barry Cukor, Sun W. Tam et al. · Nature Medicine Feb 1997 1,050
3 CDC25 Phosphatases as Potential Human Oncogenes Konstantin I. Galaktionov, Arthur K. Lee, Jens W. Eckstein et al. · Science 15 Sep 1995 506
4 CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors Linchun Jin, Haipeng Tao, Aida Karachi et al. · Nature Communications Open access 5 Sep 2019 376
5 Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts. Michele Pagano, Rainer Pepperkok, Jiří Lukáš et al. · The Journal of Cell Biology Open access Apr 1993 325
All 60 most cited papers, with filters and sorting

Which keywords describe research at 490 BioTech (United States)?

By fractional works in 2022-now, weighted toward what it does more of than the world: Immunotherapy, Cancer Immunotherapy, Tumor Regression, Lymphoma, CAR T Cells, Chimeric Antigen Receptor, Monoclonal Antibodies and Glycosylation.

▲ more of its work than of the world's◆ about the world's share▼ less than the world's

Size is fractional works in 2022-now in the topics tagged with each word; colour is the word's share of this institution's work against its share of the world's. The 40 words are chosen for being large and distinctive. Each links to the topic it comes from most.

All 40 words, with their numbers
  1. Immunotherapy7▲ 8.9×8 topics
  2. Cancer Immunotherapy7▲ 39×2 topics
  3. Tumor Regression7▲ 53×2 topics
  4. Lymphoma6▲ 35×2 topics
  5. CAR T Cells6▲ 76×1 topic
  6. Chimeric Antigen Receptor6▲ 76×1 topic
  7. Inflammation6▲ 2.4×31 topics
  8. Oxidative Stress5▲ 2.8×20 topics
  9. Cancer4▲ 2.7×23 topics
  10. Antioxidant4▲ 5.1×15 topics
  11. Chemotherapy4▲ 4.7×11 topics
  12. Monoclonal Antibodies4▲ 38×2 topics
  13. Glycosylation4▲ 28×2 topics
  14. Monoclonal Antibody3▲ 52×2 topics
  15. Antioxidant Activity3▲ 4.0×8 topics
  16. Gene Therapy3▲ 13×3 topics
  17. Thrombosis2▲ 7.8×4 topics
  18. Fc Receptors2▲ 36×1 topic
  19. Medicinal Plants2▲ 5.0×9 topics
  20. Therapeutic Antibodies2▲ 28×1 topic
  21. AAV2▲ 47×1 topic
  22. Breast Cancer2▲ 7.6×3 topics
  23. Neuroprotective2▲ 12×5 topics
  24. Viral Vectors2▲ 47×1 topic
  25. Biopharmaceuticals2▲ 33×2 topics
  26. HER22▲ 52×1 topic
  27. Metastatic2▲ 26×2 topics
  28. Neuroprotective Effects2▲ 11×4 topics
  29. Trastuzumab2▲ 33×1 topic
  30. Anti-inflammatory2▲ 5.6×9 topics
  31. Cell Culture2▲ 13×2 topics
  32. Ethical Issues2▲ 14×4 topics
  33. Proteasome Inhibitors2▲ 22×2 topics
  34. Staging System2▲ 25×2 topics
  35. Biosimilars2▲ 73×1 topic
  36. Immunogenicity2▲ 34×1 topic
  37. Minimal Residual Disease2▲ 20×2 topics
  38. Diagnosis Criteria2▲ 39×1 topic
  39. International Myeloma Working Group2▲ 39×1 topic
  40. Transcriptional Regulation2▲ 8.3×4 topics

Which research topics does 490 BioTech (United States) publish most on?

By volume in 2022-now: CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, Virus-based gene therapy research and HER2/EGFR in Cancer Research.

CAR-T cell therapy resea…6CAR-T cell therapy research: 6 fractional worksMonoclonal and Polyclona…2Monoclonal and Polyclonal Antibodies Research: 2 fractional worksVirus-based gene therapy…2Virus-based gene therapy research: 2 fractional worksHER2/EGFR in Cancer Research: 2 fractional worksBiosimilars and Bioanalytical Methods: 2 fractional worksMultiple Myeloma Researc…2Multiple Myeloma Research and Treatments: 2 fractional worksReproductive Biology and Fertility: 1 fractional worksViral Infectious Diseases and Gene Expression in Insects: 1 fractional worksMedicinal Plants and Bioactive Compounds: 1 fractional worksCoagulation, Bradykinin, Polyphosphates, and Angioedema: 1 fractional works
OncologyRadiology, Nuclear Medicine and ImagingGeneticsImmunology3 others

Area is fractional works; colour is the subfield each topic belongs to.

  1. 1 CAR-T cell therapy research Oncology 6 works
  2. 2 Monoclonal and Polyclonal Antibodies Research Radiology, Nuclear Medicine and Imaging 2 works
  3. 3 Virus-based gene therapy research Genetics 2 works
  4. 4 HER2/EGFR in Cancer Research Oncology 2 works
  5. 5 Biosimilars and Bioanalytical Methods Immunology 2 works
  6. 6 Multiple Myeloma Research and Treatments Hematology 2 works
  7. 7 Reproductive Biology and Fertility Public Health, Environmental and Occupational Health 1 works
  8. 8 Viral Infectious Diseases and Gene Expression in Insects Molecular Biology 1 works
  9. 9 Medicinal Plants and Bioactive Compounds Molecular Biology 1 works
  10. 10 Coagulation, Bradykinin, Polyphosphates, and Angioedema Genetics 1 works

How open and international is its research?

Against the world's own shares: the tick on each track. Both are shares of its output, so they sit on one scale and can be read against each other as well as against the world.

openly available42.1%not open57.9%

World: 40% of research is openly available.

with international co-authors29.4%domestic only70.6%

World: 18% is written across borders.

How has 490 BioTech (United States)'s research output changed?

Output in 2022-2025 was 132% higher than in 2018-2021.

still counting1990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is 490 BioTech (United States) as a percentage of every work published that year, 0.00025% in 2024.

still counting0.00050%0.0010%0.0015%490 BioTech (United States)0.00083% in 20251990200020102020

Fractional works of 490 BioTech (United States) over all fractional works that year. How the balance of science has shifted.

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490 BioTech (United States) on Science Explorer

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