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Topic · Molecular Biology

Extracellular vesicles in disease

Extracellular vesicles in disease is a research topic within Molecular Biology. Science Explorer counts 30k research works in it since 1953. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the biology, function, and intercellular communication mediated by exosomes and other extracellular vesicles. It covers topics such as biogenesis, microRNA transfer, cancer implications, therapeutic potential, biomarker identification, isolation techniques, and drug delivery using exosomes.

  • Exosomes
  • Extracellular Vesicles
  • Cell-to-Cell Communication
  • Biogenesis
  • MicroRNAs
  • Cancer
  • Therapeutic Potential
  • Biomarkers
  • Isolation Techniques
  • Drug Delivery
Research works
30k
fractional, since 1953
In the world top 10%
3k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+55%
the tick is no change
Largest producer
China
53% of the 10 largest, 2022-now
Extracellular vesicles in disease

Which countries lead Extracellular vesicles in disease research?

By volume, China and the United States publish the most (6.5k and 2.4k works in 2022-now).

By volume, 2022-now

  1. 1 China 6.5k works
  2. 2 United States 2.4k works
  3. 3 Italy 514 works
  4. 4 India 477 works
  5. 5 South Korea 451 works
  6. 6 Japan 415 works
  7. 7 Iran 386 works
  8. 8 Germany 351 works
  9. 9 Spain 305 works
  10. 10 United Kingdom 304 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 53.4%United States: 20.1%Italy: 4.2%India: 3.9%6 others listed: 18.2%53%largest
China6,477 · 53.4%United States2,442 · 20.1%Italy514 · 4.2%India477 · 3.9%6 others listed2,211 · 18.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead Extracellular vesicles in disease research?

By volume in 2022-now, Shanghai Jiao Tong University publishes the most Extracellular vesicles in disease research, followed by Sun Yat-sen University and Sichuan University.

By volume, 2022-now

  1. 1 Shanghai Jiao Tong UniversityChina 208 works
  2. 2 Sun Yat-sen UniversityChina 158 works
  3. 3 Sichuan UniversityChina 154 works
  4. 4 Chinese Academy of SciencesChina 136 works
  5. 5 Central South UniversityChina 124 works
  6. 6 Zhejiang UniversityChina 120 works
  7. 7 Southern Medical UniversityChina 117 works
  8. 8 Nanjing Medical UniversityChina 115 works
  9. 9 Fudan UniversityChina 115 works
  10. 10 Huazhong University of Science and TechnologyChina 113 works

Who are the leading researchers in Extracellular vesicles in disease?

The most-cited researchers publishing on Extracellular vesicles in disease include Guido Kroemer, Gad A. Getz and Shizuo Akira.

  1. 1 Guido Kroemer France 386k citations
  2. 2 Gad A. Getz United States 364k citations
  3. 3 Shizuo Akira Japan 342k citations
  4. 4 Jun Wang China 340k citations
  5. 5 Giuseppe Remuzzi Italy 328k citations
  6. 6 Gregory Y.H. Lip United Kingdom 311k citations
  7. 7 Matthias Mann Germany 308k citations
  8. 8 Róbert Langer United States 303k citations
  9. 9 Robert A. Weinberg United States 301k citations
  10. 10 Todd R. Golub United States 283k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Extracellular vesicles in disease?

The most cited paper in Extracellular vesicles in disease is "Integrating single-cell transcriptomic data across different conditions, technologies, and species" (Andrew W. Butler, Paul Hoffman, Peter Smibert et al., 2018), with 15,109 citations. Next come "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells" (13,088) and "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (11,535).

Most cited papers
#PaperReleasedCitations
1 Integrating single-cell transcriptomic data across different conditions, technologies, and species Andrew W. Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology Open access 2 Apr 2018 15,109
2 Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology 7 May 2007 13,088
3 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
4 The biology , function , and biomedical applications of exosomes Raghu K. Kalluri, Valerie S. LeBleu · Science Open access 6 Feb 2020 10,939
5 Shedding light on the cell biology of extracellular vesicles Guillaume van Niel, Gisela D’Angelo, Graça Raposo · Nature Reviews Molecular Cell Biology ReviewOpen access 17 Jan 2018 8,693
All 99 most cited papers, with filters and sorting

Where is Extracellular vesicles in disease research done?

The largest centres of Extracellular vesicles in disease research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Nanjing (China). Among places with at least 20 works in it, it is an unusually large share of all research in Luzhou, Shatin and Nantong.

Largest cities, 2022-now

  1. 1 BeijingChina 620 works
  2. 2 ShanghaiChina 616 works
  3. 3 GuangzhouChina 467 works
  4. 4 NanjingChina 321 works
  5. 5 WuhanChina 274 works
  6. 6 HangzhouChina 238 works
  7. 7 ChengduChina 222 works
  8. 8 SeoulSouth Korea 222 works
  9. 9 ChangshaChina 196 works
  10. 10 Xi'anChina 193 works

Where it is the local speciality

  1. LuzhouCN · 38.1 works10×
  2. ShatinCN · 29.9 works9.1×
  3. NantongCN · 60.3 works8.8×
  4. ZunyiCN · 22.9 works7.5×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Extracellular vesicles in disease than the world average.

See Extracellular vesicles in disease on the map

Where is the best place to study Extracellular vesicles in disease?

Among universities, judged by research, Shanghai Jiao Tong University, University of Macau and Sichuan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 16.75%fractional works in this field (log) →share of work in the world top 10% →University of MacauSichuan UniversityShanghai Jiao Tong U…Sun Yat-sen University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Shanghai Jiao Tong UniversityChina 69.415.6%5.7×208 +60.8%
2University of MacauChina 68.631.4%2.8×12 +128.5%
3Sichuan UniversityChina 66.717.1%5.3×154 +136.0%
4Sun Yat-sen UniversityChina 66.015.1%6.0×158 +59.4%
5Southern Medical UniversityChina 62.314.0%14.7×117 +102.8%
6Huazhong University of Science and TechnologyChina 62.315.5%4.9×112 +96.4%
7Nanjing Medical UniversityChina 61.813.3%10.1×116 +26.6%
8Fudan UniversityChina 61.513.9%5.7×115 +61.1%
9Harvard UniversityUnited States 61.414.7%2.7×108 +12.9%
10Jiangsu UniversityChina 59.716.9%5.6×57 +83.4%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Extracellular vesicles in disease, country by country

Is Extracellular vesicles in disease research growing?

Output in 2022-2025 was 55% higher than in 2018-2021, peaking in 2025. The fastest-growing topics are Extracellular vesicles in disease.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Extracellular vesicles in disease as a percentage of every work published that year, 0.061% in 2024.

still counting0.025%0.050%0.075%Extracellular vesicles in disease0.063% in 202519801990200020102020

Fractional works of Extracellular vesicles in disease over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Extracellular vesicles in disease9.8% in 202520102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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