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DNA and Nucleic Acid Chemistry

DNA and Nucleic Acid Chemistry is a research topic within Molecular Biology. Science Explorer counts 69k research works in it since 1950. 17.2% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the structure, topology, and biological functions of G-quadruplex DNA, particularly in relation to telomeres, therapeutic targets, and antisense oligonucleotides. It explores the potential of G-quadruplexes as targets for cancer therapy and drug design, as well as their role in genomic stability and molecular recognition.

  • G-Quadruplexes
  • DNA Structure
  • Nucleic Acids
  • Therapeutic Targets
  • Telomeres
  • Antisense Oligonucleotides
  • Biological Functions
  • Molecular Recognition
  • Drug Design
  • Genomic Stability
Research works
69k
fractional, since 1950
In the world top 10%
12k
per year above
Top-10% rate
17.2%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
-16%
the tick is no change

Which countries lead DNA and Nucleic Acid Chemistry research?

By volume, the United States and China publish the most (942 and 913 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 942 works
  2. 2 China 913 works
  3. 3 India 317 works
  4. 4 Japan 310 works
  5. 5 Germany 190 works
  6. 6 France 171 works
  7. 7 United Kingdom 150 works
  8. 8 Russia 147 works
  9. 9 Italy 140 works
  10. 10 Canada 96 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 27.9%China: 27.1%India: 9.4%Japan: 9.2%6 others listed: 26.5%28%largest
United States942 · 27.9%China913 · 27.1%India317 · 9.4%Japan310 · 9.2%6 others listed893 · 26.5%

Shares of the rows listed above, not of the whole node.

Which institutions lead DNA and Nucleic Acid Chemistry research?

By volume in 2022–2025, Centre National de la Recherche Scientifique publishes the most DNA and Nucleic Acid Chemistry research, followed by Chinese Academy of Sciences and Kyoto University.

Who are the leading researchers in DNA and Nucleic Acid Chemistry?

The most-cited researchers publishing on DNA and Nucleic Acid Chemistry include Peter A. Kollman, Luigi Ferrucci and Martin Karplus.

  1. 1 Peter A. Kollman United States 6.3k citations
  2. 2 Luigi Ferrucci United States 5.3k citations
  3. 3 Martin Karplus United States 4.7k citations
  4. 4 Chad A. Mirkin United States 4.6k citations
  5. 5 Darrin M. York United States 4.1k citations
  6. 6 Lee G. Pedersen United States 4.1k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is DNA and Nucleic Acid Chemistry research done?

The largest centres of DNA and Nucleic Acid Chemistry research in 2022–2025 are Beijing (China), Tokyo (Japan), Shanghai (China) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Novosibirsk.

Largest cities, 2022–2025

  1. 1 Beijing China 130 works
  2. 2 Tokyo Japan 84 works
  3. 3 Shanghai China 77 works
  4. 4 Paris France 74 works
  5. 5 Moscow Russia 69 works
  6. 6 Kolkata India 50 works
  7. 7 Guangzhou China 49 works
  8. 8 Wuhan China 44 works
  9. 9 Nanjing China 43 works
  10. 10 London United Kingdom 42 works

Where it is the local speciality

  1. NovosibirskRU · 34.3 works6.9×
← less than its size predictsmore →

Location quotient: how much more of its research is in DNA and Nucleic Acid Chemistry than the world average.

See DNA and Nucleic Acid Chemistry on the map

Where is the best place to study DNA and Nucleic Acid Chemistry?

Among universities, judged by research, Southwest University, University of Waterloo and Indian Association for the Cultivation of Science score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 24.5%fractional works in this node (log) →share in the world top 10% →Southwest University: 16, 29.2%University of Waterloo: 11, 31.0%Indian Association for the Cultivation of Science: 18, 9.8%Kyoto University: 20, 20.4%Hebrew University of Jerusalem: 8, 43.8%Hunan University: 16, 26.0%Konan University: 13, 12.2%McGill University: 11, 27.7%University of Chinese Academy of Sciences: 15, 16.0%Wuhan University: 14, 28.9%University of WaterlooSouthwest UniversityKyoto UniversityIndian Association f…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 Southwest UniversityChina 57.129.2%7.1×16 +47.7%
2 University of WaterlooCanada 52.131.0%4.8×11 +59.9%
3 Indian Association for the Cultivation of ScienceIndia 51.49.8%73.8×18 +24.1%
4 Kyoto UniversityJapan 48.120.4%6.8×20 -48.4%
5 Hebrew University of JerusalemIsrael 47.443.8%5.0×8 -42.8%
6 Hunan UniversityChina 47.126.0%5.4×16 0.0%
7 Konan UniversityJapan 43.912.2%197.4×13 -28.3%
8 McGill UniversityCanada 43.327.7%3.5×11 +24.5%
9 University of Chinese Academy of SciencesChina 42.216.0%2.2×15 +129.9%
10 Wuhan UniversityChina 40.828.9%2.8×14 +15.9%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is DNA and Nucleic Acid Chemistry research growing?

Output in 2018–2022 was 16% lower than in 2013–2017, peaking in 2009.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.