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Topic · Molecular Biology

Developmental Biology and Gene Regulation

Developmental Biology and Gene Regulation is a research topic within Molecular Biology. Science Explorer counts 21k research works in it since 1950. 9.9% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the Notch signaling pathway and its role in various aspects of development, including gene regulation, stem cell maintenance, embryonic development, and vertebrate origins. It also delves into the implications of Notch signaling in tumorigenesis and evolutionary biology.

  • Notch Signaling
  • Development
  • Gene Regulation
  • Stem Cells
  • Evolutionary Biology
  • Embryonic Development
  • Cell Fate
  • Zebrafish
  • Vertebrate Origins
  • Tumorigenesis
Research works
21k
fractional, since 1950
In the world top 10%
2.1k
per year above
Top-10% rate
9.9%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-9%
the tick is no change
Largest producer
United States
37% of the 10 largest, 2022-now
Developmental Biology and Gene Regulation

Which countries lead Developmental Biology and Gene Regulation research?

By volume, the United States and China publish the most (799 and 534 works in 2022-now).

By volume, 2022-now

  1. 1 United States 799 works
  2. 2 China 534 works
  3. 3 Japan 188 works
  4. 4 United Kingdom 139 works
  5. 5 Germany 133 works
  6. 6 France 112 works
  7. 7 India 69 works
  8. 8 Spain 65 works
  9. 9 Canada 59 works
  10. 10 Russia 56 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 37.1%China: 24.8%Japan: 8.7%United Kingdom: 6.4%6 others listed: 23.0%37%largest
United States799 · 37.1%China534 · 24.8%Japan188 · 8.7%United Kingdom139 · 6.4%6 others listed495 · 23.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Developmental Biology and Gene Regulation research?

By volume in 2022-now, Centre National de la Recherche Scientifique publishes the most Developmental Biology and Gene Regulation research, followed by Harvard University and Russian Academy of Sciences.

By volume, 2022-now

  1. 1 Centre National de la Recherche ScientifiqueFrance 45 works
  2. 2 Harvard UniversityUnited States 33 works
  3. 3 Russian Academy of SciencesRussia 33 works
  4. 4 Chinese Academy of SciencesChina 25 works
  5. 5 Max Planck SocietyGermany 20 works
  6. 6 National Institutes of HealthUnited States 19 works
  7. 7 Anhui Normal UniversityChina 17 works
  8. 8 Consejo Superior de Investigaciones CientíficasSpain 17 works
  9. 9 University of CambridgeUnited Kingdom 16 works
  10. 10 University of ChicagoUnited States 15 works

Who are the leading researchers in Developmental Biology and Gene Regulation?

The most-cited researchers publishing on Developmental Biology and Gene Regulation include Eric S. Lander, Peer Bork and Jun Wang.

  1. 1 Eric S. Lander United States 524k citations
  2. 2 Peer Bork Germany 396k citations
  3. 3 Jun Wang China 340k citations
  4. 4 Robert A. Weinberg United States 301k citations
  5. 5 Sudhir Kumar United States 295k citations
  6. 6 Richard A. Gibbs United States 292k citations
  7. 7 Michael Karin United States 276k citations
  8. 8 Gordon Brent Mills United States 265k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Developmental Biology and Gene Regulation?

The most cited paper in Developmental Biology and Gene Regulation is "Targeted gene expression as a means of altering cell fates and generating dominant phenotypes" (Andrea H. Brand, Norbert Perrimon, 1993), with 9,930 citations. Next come "Notch Signaling: Cell Fate Control and Signal Integration in Development" (5,977) and "MicroRNA targets in Drosophila" (3,822).

Most cited papers
#PaperReleasedCitations
1 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes Andrea H. Brand, Norbert Perrimon · Development Jun 1993 9,930
2 Notch Signaling: Cell Fate Control and Signal Integration in Development Spyros Artavanis‐Tsakonas, Matthew D. Rand, Robert J. Lake · Science 30 Apr 1999 5,977
3 MicroRNA targets in Drosophila Anton James Enright, Bino John, Ulrike Gaul et al. · Genome biology Open access 12 Dec 2003 3,822
4 The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism Raphael Kopan, Ma. Xenia G. Ilagan · Cell Open access Apr 2009 3,732
5 Preservation of Duplicate Genes by Complementary, Degenerative Mutations Allan G. Force, Michael F. Lynch, F. Bryan Pickett et al. · Genetics Open access Apr 1999 3,611
All 100 most cited papers, with filters and sorting

Where is Developmental Biology and Gene Regulation research done?

The largest centres of Developmental Biology and Gene Regulation research in 2022-now are Paris (France), Beijing (China), Tokyo (Japan) and Shanghai (China).

Largest cities, 2022-now

  1. 1 ParisFrance 71 works
  2. 2 BeijingChina 70 works
  3. 3 TokyoJapan 49 works
  4. 4 ShanghaiChina 48 works
  5. 5 LondonUnited Kingdom 45 works
  6. 6 New YorkUnited States 43 works
  7. 7 GuangzhouChina 38 works
  8. 8 CambridgeUnited States 29 works
  9. 9 MoscowRussia 29 works
  10. 10 QingdaoChina 25 works
See Developmental Biology and Gene Regulation on the map

Where is the best place to study Developmental Biology and Gene Regulation?

Among universities, judged by research, Harvard University, University of Cambridge and Columbia University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 14.88%fractional works in this field (log) →share of work in the world top 10% →University of Cambri…Harvard UniversityPrinceton UniversityColumbia University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 80.916.8%4.6×33 -12.4%
2University of CambridgeUnited Kingdom 66.121.3%5.9×16 -42.1%
3Columbia UniversityUnited States 62.213.7%5.3×13 +14.2%
4Princeton UniversityUnited States 61.015.5%10.5×10 +14.6%
5Johns Hopkins UniversityUnited States 57.412.2%4.0×14 +26.2%
6New York UniversityUnited States 55.919.8%4.6×12 -13.8%
7Stanford UniversityUnited States 55.119.3%3.1×10 -13.7%
8University of CincinnatiUnited States 52.017.5%8.1×11 +4.1%
9University College LondonUnited Kingdom 51.48.8%4.1×14 -17.4%
10University of EdinburghUnited Kingdom 48.73.9%6.7×13 +139.9%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Developmental Biology and Gene Regulation, country by country

Is Developmental Biology and Gene Regulation research growing?

Output in 2022-2025 was 9% lower than in 2018-2021, peaking in 2026.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Developmental Biology and Gene Regulation as a percentage of every work published that year, 0.0062% in 2024.

still counting0.020%0.040%0.060%Developmental Biology and Gene Regulation0.010% in 202519801990200020102020

Fractional works of Developmental Biology and Gene Regulation over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Developmental Biology and Gene Regulation10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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