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Topic · Molecular Biology

Advanced biosensing and bioanalysis techniques

Advanced biosensing and bioanalysis techniques is a research topic within Molecular Biology. Science Explorer counts 113k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the use of DNA as a versatile tool for creating nanoscale shapes, self-assembled structures, and functional biomolecular devices. It explores applications in biosensors, aptamers, nanoparticle-based bio-barcode detection, electrochemistry, and cancer diagnostics.

  • DNA nanotechnology
  • self-assembly
  • biosensors
  • aptamers
  • nanoparticles
  • electrochemistry
  • molecular machines
  • nanoscale shapes
  • biomolecular interactions
  • cancer diagnostics
Research works
113k
fractional, since 1950
In the world top 10%
11k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
+21%
the tick is no change
Largest producer
China
58% of the 10 largest, 2022-now
Advanced biosensing and bioanalysis techniques

Which countries lead Advanced biosensing and bioanalysis techniques research?

By volume, China and the United States publish the most (13k and 2.9k works in 2022-now).

By volume, 2022-now

  1. 1 China 13k works
  2. 2 United States 2.9k works
  3. 3 India 2.3k works
  4. 4 South Korea 808 works
  5. 5 Japan 755 works
  6. 6 Iran 734 works
  7. 7 Germany 593 works
  8. 8 United Kingdom 519 works
  9. 9 Italy 468 works
  10. 10 France 443 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 57.7%United States: 12.9%India: 10.3%South Korea: 3.6%6 others listed: 15.6%58%largest
China13k · 57.7%United States2,899 · 12.9%India2,311 · 10.3%South Korea808 · 3.6%6 others listed3,512 · 15.6%

Shares of the rows listed above, not of the whole node.

Which institutions lead Advanced biosensing and bioanalysis techniques research?

By volume in 2022-now, Chinese Academy of Sciences publishes the most Advanced biosensing and bioanalysis techniques research, followed by Shanghai Jiao Tong University and Centre National de la Recherche Scientifique.

By volume, 2022-now

  1. 1 Chinese Academy of SciencesChina 611 works
  2. 2 Shanghai Jiao Tong UniversityChina 221 works
  3. 3 Centre National de la Recherche ScientifiqueFrance 202 works
  4. 4 Southwest UniversityChina 191 works
  5. 5 Nanjing UniversityChina 185 works
  6. 6 Sichuan UniversityChina 172 works
  7. 7 Jilin UniversityChina 162 works
  8. 8 Hunan UniversityChina 160 works
  9. 9 Russian Academy of SciencesRussia 153 works
  10. 10 Southeast UniversityChina 144 works

Who are the leading researchers in Advanced biosensing and bioanalysis techniques?

The most-cited researchers publishing on Advanced biosensing and bioanalysis techniques include Christopher J L Murray, Eric S. Lander and Zhong Lin Wang.

  1. 1 Christopher J L Murray United States 583k citations
  2. 2 Eric S. Lander United States 524k citations
  3. 3 Zhong Lin Wang United States 491k citations
  4. 4 Yoshua Bengio Canada 476k citations
  5. 5 Rob Knight United States 468k citations
  6. 6 Michaël Grätzel Switzerland 458k citations
  7. 7 Robert John Tibshirani United States 396k citations
  8. 8 Bert Vogelstein United States 373k citations
  9. 9 Elaine R. Mardis United States 346k citations
  10. 10 Jun Wang China 340k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Advanced biosensing and bioanalysis techniques?

The most cited paper in Advanced biosensing and bioanalysis techniques is "Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays" (Tim R. Mosmann, 1983), with 56,216 citations. Next come "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity" (25,160) and "A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity" (17,763).

Most cited papers
#PaperReleasedCitations
1 Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays Tim R. Mosmann · Journal of Immunological Methods Dec 1983 56,216
2 A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity Andrew P. Feinberg, Bert Vogelstein · Analytical Biochemistry Jul 1983 25,160
3 A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science Open access 29 Jun 2012 17,763
4 A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid K. Burton · Biochemical Journal Open access Feb 1956 14,144
5 A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules Wendy D. Cornell, Piotr Cieplak, Christopher I. Bayly et al. · Journal of the American Chemical Society May 1995 13,239
All 100 most cited papers, with filters and sorting

Where is Advanced biosensing and bioanalysis techniques research done?

The largest centres of Advanced biosensing and bioanalysis techniques research in 2022-now are Beijing (China), Shanghai (China), Nanjing (China) and Guangzhou (China). Among places with at least 20 works in it, it is an unusually large share of all research in Changsha, Nanjing and Baise City.

Largest cities, 2022-now

  1. 1 BeijingChina 1.4k works
  2. 2 ShanghaiChina 837 works
  3. 3 NanjingChina 742 works
  4. 4 GuangzhouChina 542 works
  5. 5 ChongqingChina 537 works
  6. 6 WuhanChina 498 works
  7. 7 JinanChina 414 works
  8. 8 HangzhouChina 407 works
  9. 9 QingdaoChina 380 works
  10. 10 SeoulSouth Korea 379 works

Where it is the local speciality

  1. Changsha40.6 works33×
  2. Nanjing40.7 works14×
  3. Baise CityCN · 21.8 works11×
  4. LiaochengCN · 46.6 works8.6×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Advanced biosensing and bioanalysis techniques than the world average.

See Advanced biosensing and bioanalysis techniques on the map

Where is the best place to study Advanced biosensing and bioanalysis techniques?

Among universities, judged by research, Jiangsu University, Nanchang University and Nanjing University score highest, combining citation excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%30%mean 17.83%fractional works in this field (log) →share of work in the world top 10% →Jiangsu UniversityNanchang UniversityShanghai Jiao Tong U…Nanjing University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Citation excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Jiangsu UniversityChina 76.619.6%7.2×138 +41.0%
2Nanchang UniversityChina 71.618.4%6.6×119 +27.8%
3Nanjing UniversityChina 69.413.2%8.4×185 +7.9%
4Shanghai Jiao Tong UniversityChina 69.313.9%3.2×221 +38.6%
5Hunan UniversityChina 68.414.5%9.4×160 +9.1%
6Zhejiang Sci-Tech UniversityChina 68.427.0%4.8×35 +207.9%
7Sichuan UniversityChina 67.816.1%3.1×172 +38.0%
8Chinese University of Hong Kong, ShenzhenChina 67.723.9%4.9×22 +543.4%
9Qingdao UniversityChina 67.417.3%5.7×94 +63.5%
10Jilin UniversityChina 66.414.4%5.9×162 +32.3%

Universities only. The score blends citation excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Advanced biosensing and bioanalysis techniques, country by country

Is Advanced biosensing and bioanalysis techniques research growing?

Output in 2022-2025 was 21% higher than in 2018-2021, peaking in 2022. The fastest-growing topics are Advanced biosensing and bioanalysis techniques.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Advanced biosensing and bioanalysis techniques as a percentage of every work published that year, 0.12% in 2024.

still counting0.050%0.10%0.15%Advanced biosensing and bioanalysis techniques0.11% in 202519801990200020102020

Fractional works of Advanced biosensing and bioanalysis techniques over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Advanced biosensing and bioanalysis techniques9.7% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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