DNA Repair Mechanisms
DNA Repair Mechanisms is a research topic within Molecular Biology. Science Explorer counts 56k research works in it since 1950. 23.5% of them reached the world's top 10% most cited for their field and year.
This cluster of papers focuses on the molecular mechanisms of the DNA damage response, including DNA repair pathways, genomic instability, the role of ATM and ATR kinases, homologous recombination, cell cycle checkpoints, and their implications in cancer biology. It also explores the involvement of histone H2AX and chromatin in maintaining genome stability.
- DNA Damage
- Repair
- Genomic Instability
- ATM and ATR Kinases
- Homologous Recombination
- Cell Cycle Checkpoints
- Cancer
- Histone H2AX
- Chromatin
- Genome Stability
- Research works
- 56k fractional, since 1950
- In the world top 10%
- 13k per year above
- Top-10% rate
- 23.5% share of its works in the world top 10%
- Growth, 2013–17 → 2018–22
- -10% the tick is no change
Which countries lead DNA Repair Mechanisms research?
By volume, the United States and China publish the most (1.4k and 815 works in 2022–2025).
By volume, 2022–2025
- 1 United States 1.4k works
- 2 China 815 works
- 3 Japan 267 works
- 4 United Kingdom 257 works
- 5 France 214 works
- 6 Germany 206 works
- 7 India 181 works
- 8 Italy 134 works
- 9 Russia 133 works
- 10 Canada 115 works
How concentrated that is
The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.
Shares of the rows listed above, not of the whole node.
Which institutions lead DNA Repair Mechanisms research?
By volume in 2022–2025, University of North Carolina at Chapel Hill publishes the most DNA Repair Mechanisms research, followed by The University of Texas MD Anderson Cancer Center and Centre National de la Recherche Scientifique.
By volume, 2022–2025
- 1 University of North Carolina at Chapel HillUnited States 33 works
- 2 The University of Texas MD Anderson Cancer CenterUnited States 31 works
- 3 Centre National de la Recherche ScientifiqueFrance 27 works
- 4 Harvard UniversityUnited States 23 works
- 5 Memorial Sloan Kettering Cancer CenterUnited States 21 works
- 6 Cornell UniversityUnited States 18 works
- 7 InsermFrance 17 works
- 8 Washington University in St. LouisUnited States 17 works
- 9 University of OxfordUnited Kingdom 17 works
- 10 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 17 works
Who are the leading researchers in DNA Repair Mechanisms?
The most-cited researchers publishing on DNA Repair Mechanisms include David Botstein, Guido Kroemer and Barry Halliwell.
- 1 David Botstein United States 6.7k citations
- 2 Guido Kroemer France 4.2k citations
- 3 Barry Halliwell United Kingdom 4k citations
Ranked by citations received across their whole record, among researchers with at least three works on this topic.
Where is DNA Repair Mechanisms research done?
The largest centres of DNA Repair Mechanisms research in 2022–2025 are Beijing (China), New York (United States), Paris (France) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda and Novosibirsk.
Largest cities, 2022–2025
Where it is the local speciality
- BethesdaUS · 46.2 works8.1×
- NovosibirskRU · 34.2 works6.1×
Location quotient: how much more of its research is in DNA Repair Mechanisms than the world average.
Where is the best place to study DNA Repair Mechanisms?
Among universities, judged by research, University of Sussex, University of Copenhagen and Rockefeller University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.
One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.
| # | University | Score | Top 10% | Specialisation | Works | Growth |
|---|---|---|---|---|---|---|
| 1 | University of SussexUnited Kingdom | 55.8 | 41.6% | 9.6× | 9 | -40.1% |
| 2 | University of CopenhagenDenmark | 50.0 | 37.3% | 4.1× | 13 | +34.2% |
| 3 | Rockefeller UniversityUnited States | 48.4 | 20.7% | 49.9× | 14 | -7.0% |
| 4 | The University of Texas at San Antonio Health Science CenterUnited States | 46.1 | 25.2% | 13.6× | 9 | +1.3% |
| 5 | Vanderbilt UniversityUnited States | 45.2 | 22.6% | 8.4× | 16 | -27.2% |
| 6 | University of CambridgeUnited Kingdom | 44.4 | 39.0% | 2.6× | 13 | +1.5% |
| 7 | University of OxfordUnited Kingdom | 44.3 | 36.0% | 2.8× | 17 | -33.6% |
| 8 | Harvard UniversityUnited States | 43.4 | 24.8% | 4.0× | 23 | -36.3% |
| 9 | Cornell UniversityUnited States | 40.4 | 25.7% | 3.9× | 18 | -4.5% |
| 10 | University of North Carolina at Chapel HillUnited States | 39.4 | 11.5% | 4.2× | 33 | +40.7% |
Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.
Is DNA Repair Mechanisms research growing?
Output in 2018–2022 was 10% lower than in 2013–2017, peaking in 2013. The fastest-growing topics are DNA Repair Mechanisms.
The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.
Which topics inside it are moving
Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.