Topic · DNA Repair Mechanisms
Most cited papers in DNA Repair Mechanisms
What are the most cited papers in DNA Repair Mechanisms?
The most cited paper in DNA Repair Mechanisms is "The Hallmarks of Cancer" (Douglas Hanahan, Robert A. Weinberg, 2000), with 28,893 citations. Next come "A simple salting out procedure for extracting DNA from human nucleated cells" (20,633) and "Signatures of mutational processes in human cancer" (10,284).
Showing 50 of 100 papers. Every paper with more than 1,907 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The Hallmarks of Cancer Douglas Hanahan, Robert A. Weinberg · Cell | 2000 | 28,893 |
| 2 | A simple salting out procedure for extracting DNA from human nucleated cells S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research | 1988 | 20,633 |
| 3 | Signatures of mutational processes in human cancer Australian Pancreatic Cancer Genome Initiative et al. · Nature | 14 Aug 2013 | 10,284 |
| 4 | Crystal structure of the nucleosome core particle at 2.8 Å resolution Karolin Luger, Armin W. Mäder, Robin K. Richmond et al. · Nature | Sep 1997 | 9,627 |
| 5 | A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels William M. Bonner, Ronald Alfred Laskey · European Journal of Biochemistry | Jul 1974 | 8,651 |
| 6 | Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing Fred C. Tenover, R D Arbeit, Richard Vernon Goering et al. · Journal of Clinical Microbiology | Sep 1995 | 8,250 |
| 7 | Genomic sequencing. George M. Church, W Gilbert · Proceedings of the National Academy of Sciences | Apr 1984 | 8,225 |
| 8 | p53 Mutations in Human Cancers Monica C. Hollstein, David Sidransky, Bert Vogelstein et al. · Science | 5 Jul 1991 | 8,130 |
| 9 | Revised methods for the Salmonella mutagenicity test Dorothy M. Maron, Bruce N. Ames · Mutation Research/Environmental Mutagenesis and Related Subjects | Mar 1983 | 7,400 |
| 10 | Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature | Apr 2005 | 6,785 |
| 11 | The DNA-damage response in human biology and disease Stephen P. Jackson, Jiří Bártek · Nature | 20 Oct 2009 | 6,194 |
| 12 | A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1 Yoshio Miki et al. · Science | 7 Oct 1994 | 6,134 |
| 13 | The limited in vitro lifetime of human diploid cell strains Leonard Hayflick · Experimental Cell Research | Mar 1965 | 5,907 |
| 14 | Telomeres shorten during ageing of human fibroblasts Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature | May 1990 | 5,775 |
| 15 | DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139 Emmy P. Rogakou, Duane R. Pilch, Ann H. Orr et al. · Journal of Biological Chemistry | Mar 1998 | 5,501 |
| 16 | Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature | 13 Apr 2005 | 5,263 |
| 17 | Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ W. David Benton, Ronald W. Davis · Science | 8 Apr 1977 | 4,662 |
| 18 | Precise Measurement of the G+C Content of Deoxyribonucleic Acid by High-Performance Liquid Chromatography M. K. M. Mesbah, USHA PREMACHANDRAN, William B. Whitman · International Journal of Systematic Bacteriology | Apr 1989 | 4,557 |
| 19 | The DNA Damage Response: Making It Safe to Play with Knives Alberto Ciccia, Stephen J. Elledge · Molecular Cell | Oct 2010 | 4,446 |
| 20 | Genetic instabilities in human cancers Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein · Nature | Dec 1998 | 4,192 |
| 21 | Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature Julius Marmur, Paul M. Doty · Journal of Molecular Biology | Jul 1962 | 4,109 |
| 22 | A membrane-filter technique for the detection of complementary DNA David T. Denhardt · Biochemical and Biophysical Research Communications | Jun 1966 | 3,945 |
| 23 | Genome maintenance mechanisms for preventing cancer Jan H.J. Hoeijmakers · Nature | May 2001 | 3,940 |
| 24 | A complementation analysis of the restriction and modification of DNA in Escherichia coli Herbert W. Boyer, Daisy Roulland-Dussoix · Journal of Molecular Biology | May 1969 | 3,863 |
| 25 | DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation Christopher J. Bakkenist, Michael B. Kastan · Nature | 2003 | 3,474 |
| 26 | Identification of a specific telomere terminal transferase activity in tetrahymena extracts Carol W. Greider, Elizabeth Helen Blackburn · Cell | Dec 1985 | 3,449 |
| 27 | Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. J L Weber, Paula E. May · PubMed | Mar 1989 | 3,427 |
| 28 | Cisplatin: mode of cytotoxic action and molecular basis of resistance Zahid Hussain Siddik · Oncogene | 20 Oct 2003 | 3,351 |
| 29 | Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints Aziz Sancar, Laura A. Lindsey‐Boltz, Keziban Ünsal-Kaçmaz et al. · Annual Review of Biochemistry | Jun 2004 | 3,341 |
| 30 | Oxidative DNA damage: mechanisms, mutation, and disease Marcus S. Cooke, Mark Dennis Evans, Miral Dizdaroğlu et al. · The FASEB Journal | Jul 2003 | 3,252 |
| 31 | The DNA damage response: putting checkpoints in perspective Bin‐Bing S. Zhou, Stephen J. Elledge · Nature | Nov 2000 | 3,230 |
| 32 | Microsatellite Instability in Cancer of the Proximal Colon Stephen N. Thibodeau, Gary D. Bren, Daniel J. Schaid · Science | 7 May 1993 | 3,153 |
| 33 | ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage Shuhei Matsuoka, Bryan A. Ballif, Agata Smogorzewska et al. · Science | 25 May 2007 | 3,132 |
| 34 | A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell | Nov 1992 | 3,089 |
| 35 | Shelterin: the protein complex that shapes and safeguards human telomeres Titia de Lange · Genes & Development | 15 Sep 2005 | 3,078 |
| 36 | Checkpoints: Controls That Ensure the Order of Cell Cycle Events Leland H. Hartwell, Ted A. Weinert · Science | 3 Nov 1989 | 3,060 |
| 37 | Structure, Recognition, and Processing of Cisplatin−DNA Adducts Elizabeth R. Jamieson, Stephen J. Lippard · Chemical Reviews | 14 Aug 1999 | 2,952 |
| 38 | The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway Michael R. Lieber · Annual Review of Biochemistry | 7 Jun 2010 | 2,911 |
| 39 | The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer Richard A. Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell | Dec 1993 | 2,908 |
| 40 | The Comet Assay for DNA Damage and Repair: Principles, Applications, and Limitations Andrew Richard Collins · Molecular Biotechnology | 2004 | 2,887 |
| 41 | Cell-cycle checkpoints and cancer Michael B. Kastan, Jiří Bártek · Nature | Nov 2004 | 2,852 |
| 42 | A DNA damage checkpoint response in telomere-initiated senescence Fabrizio d’Adda di Fagagna, Philip M. Reaper, Lorena Clay-Farrace et al. · Nature | Nov 2003 | 2,835 |
| 43 | Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science | 20 Nov 1998 | 2,828 |
| 44 | Molecular mechanisms of cisplatin resistance Lorenzo Galluzzi, Laura Senovilla, Ilio Vitale et al. · Oncogene | 5 Sep 2011 | 2,825 |
| 45 | Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion Victoria Campuzano et al. · Science | 8 Mar 1996 | 2,812 |
| 46 | A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase Kinneret Savitsky et al. · Science | 23 Jun 1995 | 2,809 |
| 47 | Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes Lee Zou, Stephen J. Elledge · Science | 6 Jun 2003 | 2,737 |
| 48 | Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Yurij Ionov, Miguel Angel Peinado, Sergei R. Malkhosyan et al. · Nature | Jun 1993 | 2,735 |
| 49 | Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA Stanley N. Cohen, Annie C. Y. Chang, Leslie Hsu · Proceedings of the National Academy of Sciences | Aug 1972 | 2,731 |
| 50 | DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature | Apr 2005 | 2,714 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.