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Most cited papers in Extracellular vesicles in disease

What are the most cited papers in Extracellular vesicles in disease?

The most cited paper in Extracellular vesicles in disease is "Integrating single-cell transcriptomic data across different conditions, technologies, and species" (Andrew W. Butler, Paul Hoffman, Peter Smibert et al., 2018), with 15,109 citations. Next come "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells" (13,088) and "Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines" (11,535).

Showing 50 of 99 papers. Every paper with more than 1,654 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Integrating single-cell transcriptomic data across different conditions, technologies, and species Andrew W. Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology Open access 2 Apr 2018 15,109
2 Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology 7 May 2007 13,088
3 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Clotilde Théry et al. · Journal of Extracellular Vesicles Open access382 authors 23 Nov 2018 11,535
4 The biology , function , and biomedical applications of exosomes Raghu K. Kalluri, Valerie S. LeBleu · Science Open access 6 Feb 2020 10,939
5 Shedding light on the cell biology of extracellular vesicles Guillaume van Niel, Gisela D’Angelo, Graça Raposo · Nature Reviews Molecular Cell Biology ReviewOpen access 17 Jan 2018 8,693
6 Extracellular vesicles: Exosomes, microvesicles, and friends Graça Raposo, Willem Stoorvogel · The Journal of Cell Biology Open access 18 Feb 2013 8,242
7 Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles Marina Colombo, Graça Raposo, Clotilde Théry · Annual Review of Cell and Developmental Biology Review 22 Aug 2014 6,348
8 Biological properties of extracellular vesicles and their physiological functions María Yáñez‐Mó et al. · Journal of Extracellular Vesicles Open access 2015 6,130
9 Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids Clotilde Théry, Sebastián Amigorena, Graça Raposo et al. · Current Protocols in Cell Biology Mar 2006 5,870
10 Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage Dvir Aran, Agnieszka P. Looney, Leqian Liu et al. · Nature Immunology Open access 4 Jan 2019 5,566
11 Exosomes: composition, biogenesis and function Clotilde Théry, Laurence Zitvogel, Sebastián Amigorena · Nature reviews. Immunology Review Aug 2002 5,446
12 Tumour exosome integrins determine organotropic metastasis Ayuko Hoshino et al. · Nature Open access 28 Oct 2015 5,240
13 Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers Johan Skog, Tom Würdinger, Sjoerd van Rijn et al. · Nature Cell Biology Open access 16 Nov 2008 5,078
14 Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin et al. · Nature Biotechnology 20 Mar 2011 4,972
15 DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors Christopher S. McGinnis, Lyndsay M. Murrow, Zev J. Gartner · Cell Systems Open access Apr 2019 4,865
16 Human mesenchymal stem cells modulate allogeneic immune cell responses Sudeepta Aggarwal, Mark F. Pittenger · Blood Open access 20 Oct 2004 4,565
17 Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches Joshua A Welsh et al. · Journal of Extracellular Vesicles Open access Feb 2024 4,377
18 Membrane vesicles as conveyors of immune responses Clotilde Théry, Matías Ostrowski, Élodie Segura · Nature reviews. Immunology Review 5 Jun 2009 3,908
19 Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication Mathilde Mathieu, Lorena Martin Jaular, Grégory Lavieu et al. · Nature Cell Biology 11 Dec 2018 3,861
20 Autophagy: cellular and molecular mechanisms D.R. Glick, Sandra Barth, Kay F. Macleod · The Journal of Pathology Open access 3 Feb 2010 3,845
21 Mesenchymal stem cells in health and disease Antonio Uccelli, Lorenzo Moretta, Vito Pistoia · Nature reviews. Immunology Review 19 Aug 2008 3,821
22 Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET Héctor Peinado et al. · Nature Medicine Open access 27 May 2012 3,771
23 Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes Katarina Trajković, Chieh Hsu, Salvatore Chiantia et al. · Science Open access 28 Feb 2008 3,678
24 Communication by Extracellular Vesicles: Where We Are and Where We Need to Go Mercedes Tkach, Clotilde Théry · Cell Open access Mar 2016 3,564
25 B lymphocytes secrete antigen-presenting vesicles. Graça Raposo, Hans W. Nijman, Willem Stoorvogel et al. · The Journal of Experimental Medicine Open access Mar 1996 3,552
26 Extracellular vesicles: biology and emerging therapeutic opportunities Samir EL Andaloussi, Imre Mäger, Xandra O. Breakefield et al. · Nature Reviews Drug Discovery Review 15 Apr 2013 3,543
27 Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes Joanna Kowal, Guillaume Arras, Marina Colombo et al. · Proceedings of the National Academy of Sciences Open access 8 Feb 2016 3,517
28 Simultaneous epitope and transcriptome measurement in single cells Marlon Stoeckius, Christoph Hafemeister, William Stephenson et al. · Nature Methods Open access 31 Jul 2017 3,429
29 Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis Laura M. Doyle, Michael Zhuo Wang · Cells Open access 15 Jul 2019 3,331
30 Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma Jason D. Arroyo, John R. Chevillet, Evan M. Kroh et al. · Proceedings of the National Academy of Sciences Open access 7 Mar 2011 3,316
31 MicroRNAs Modulate Hematopoietic Lineage Differentiation Chang‐Zheng Chen, Ling Li, Harvey F. Lodish et al. · Science Open access 8 Dec 2003 3,277
32 Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Kiichi Nakahira, Jeffrey A. Haspel, Vijay A. K. Rathinam et al. · Nature Immunology Open access 12 Dec 2010 3,055
33 Reassessment of Exosome Composition Dennis K. Jeppesen, Aidan M. Fenix, Jeffrey L. Franklin et al. · Cell Open access Apr 2019 3,032
34 Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer Yijing Liu, Pravin Bhattarai, Zhifei Dai et al. · Chemical Society Reviews ReviewOpen access 27 Sep 2018 2,929
35 Glypican-1 identifies cancer exosomes and detects early pancreatic cancer Sónia A. Melo, Linda B. Luecke, Christoph Kahlert et al. · Nature Open access 24 Jun 2015 2,923
36 Routes and mechanisms of extracellular vesicle uptake Laura Ann Mulcahy, Ryan Charles Pink, David Raul Francisco Carter · Journal of Extracellular Vesicles Open access 2014 2,870
37 Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response Gang Chen et al. · Nature Open access Aug 2018 2,867
38 Exosomes Dirk Michiel Pegtel, Stephen John Gould · Annual Review of Biochemistry ReviewOpen access 20 Jun 2019 2,810
39 Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors Laleh Haghverdi, Aaron T. L. Lun, Michael David Morgan et al. · Nature Biotechnology Open access 2 Apr 2018 2,808
40 Rab27a and Rab27b control different steps of the exosome secretion pathway Matías Ostrowski, Nuno Carmo, Sophie Krumeich et al. · Nature Cell Biology Open access 6 Dec 2009 2,805
41 The MicroRNA Spectrum in 12 Body Fluids Jessica A. Weber, David H. Baxter, Shile Zhang et al. · Clinical Chemistry Open access 17 Sep 2010 2,779
42 MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins Kasey C. Vickers, Brian T. Palmisano, Bassem M. Shoucri et al. · Nature Cell Biology Open access 20 Mar 2011 2,749
43 Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles Jan O. Lötvall, Andrew Francis Hill, Fred H. Hochberg et al. · Journal of Extracellular Vesicles Open access 2014 2,741
44 Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto et al. · Nature Open access Jun 2017 2,668
45 Exosomes: Extracellular organelles important in intercellular communication Suresh Mathivanan, Hong Long Ji, Richard J. Simpson · Journal of Proteomics 2 Jul 2010 2,578
46 SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues Carly G.K. Ziegler et al. · Cell Open access121 authors 27 Apr 2020 2,500
47 Current best practices in single‐cell RNA‐seq analysis: a tutorial Malte D. Luecken, Fabian Joachim Theis · Molecular Systems Biology Open access Jun 2019 2,497
48 Standardization of sample collection, isolation and analysis methods in extracellular vesicle research Kenneth Whitaker Witwer, Edit I. Buzás, Lynne Bemis et al. · Journal of Extracellular Vesicles Open access 2013 2,457
49 Exosomes – vesicular carriers for intercellular communication Mikael Simons, Graça Raposo · Current Opinion in Cell Biology Review 12 May 2009 2,427
50 Current knowledge on exosome biogenesis and release Nina Pettersen Hessvik, Alicia Llorente · Cellular and Molecular Life Sciences Open access 21 Jul 2017 2,420

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.