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Topic · Genetics

Coagulation, Bradykinin, Polyphosphates, and Angioedema

Coagulation, Bradykinin, Polyphosphates, and Angioedema is a research topic within Genetics. Science Explorer counts 31k research works in it since 1950. 16.4% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the molecular mechanisms, pathophysiological consequences, and clinical management of Hereditary Angioedema. It covers topics such as the role of kinin receptors, coagulation factors XII and XI, polyphosphate, C1 inhibitor deficiency, and the use of bradykinin-receptor antagonists in the treatment of angioedema. Additionally, it explores the involvement of tissue kallikreins and the contact activation system in the disease pathology.

  • Hereditary Angioedema
  • Kinin Receptor Family
  • Coagulation Factor XII
  • Polyphosphate
  • C1 Inhibitor Deficiency
  • Bradykinin-Receptor Antagonist
  • Factor XI Antisense Oligonucleotide
  • Tissue Kallikreins
  • Contact Activation System
  • Thrombosis
Research works
31k
fractional, since 1950
In the world top 10%
5.1k
per year above
Top-10% rate
16.4%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+17%
the tick is no change

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Coagulation, Bradykinin, Polyphosphates, and Angioedema research?

By volume, the United States and China publish the most (966 and 380 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 966 works
  2. 2 China 380 works
  3. 3 Germany 240 works
  4. 4 Japan 234 works
  5. 5 Italy 180 works
  6. 6 France 178 works
  7. 7 India 176 works
  8. 8 United Kingdom 150 works
  9. 9 Spain 141 works
  10. 10 Türkiye 106 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 35.1%China: 13.8%Germany: 8.7%Japan: 8.5%6 others listed: 33.8%35%largest
United States966 · 35.1%China380 · 13.8%Germany240 · 8.7%Japan234 · 8.5%6 others listed931 · 33.8%

Shares of the rows listed above, not of the whole node.

Which institutions lead Coagulation, Bradykinin, Polyphosphates, and Angioedema research?

By volume in 2022–2025, University of North Carolina at Chapel Hill publishes the most Coagulation, Bradykinin, Polyphosphates, and Angioedema research, followed by Charité - Universitätsmedizin Berlin and University of Lübeck.

Who are the leading researchers in Coagulation, Bradykinin, Polyphosphates, and Angioedema?

The most-cited researchers publishing on Coagulation, Bradykinin, Polyphosphates, and Angioedema include Giuseppe Remuzzi, Rhian M. Touyz and Zena Werb.

  1. 1 Giuseppe Remuzzi Italy 8.1k citations
  2. 2 Rhian M. Touyz United Kingdom 3.4k citations
  3. 3 Zena Werb United States 3.3k citations
  4. 4 Thomas Schwarz United States 3.1k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Coagulation, Bradykinin, Polyphosphates, and Angioedema research done?

The largest centres of Coagulation, Bradykinin, Polyphosphates, and Angioedema research in 2022–2025 are Paris (France), Beijing (China), Tokyo (Japan) and London (United Kingdom).

Largest cities, 2022–2025

  1. 1 Paris France 70 works
  2. 2 Beijing China 59 works
  3. 3 Tokyo Japan 54 works
  4. 4 London United Kingdom 51 works
  5. 5 New York United States 50 works
  6. 6 Madrid Spain 46 works
  7. 7 Berlin Germany 39 works
  8. 8 Boston United States 35 works
  9. 9 Moscow Russia 32 works
  10. 10 Istanbul Türkiye 31 works
See Coagulation, Bradykinin, Polyphosphates, and Angioedema on the map

Where is the best place to study Coagulation, Bradykinin, Polyphosphates, and Angioedema?

Among universities, judged by research, University of Lübeck, Humboldt-Universität zu Berlin and Oregon Health & Science University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%60%mean 21.3%fractional works in this node (log) →share in the world top 10% →University of Lübeck: 14, 24.2%Humboldt-Universität zu Berlin: 8, 51.5%Oregon Health & Science University: 10, 34.6%Post Graduate Institute of Medical Education and Research: 12, 9.4%Semmelweis University: 11, 15.0%Medical University of Warsaw: 8, 7.1%McMaster University: 10, 23.1%Medical University of Vienna: 9, 14.5%Nara Medical University: 9, 8.8%University of California San Diego: 11, 24.8%Humboldt-Universität…Oregon Health & Scie…University of LübeckPost Graduate Instit…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 University of LübeckGermany 62.724.2%26.1×14 +45.7%
2 Humboldt-Universität zu BerlinGermany 55.251.5%6.1×8
3 Oregon Health & Science UniversityUnited States 52.834.6%8.7×10 +52.1%
4 Post Graduate Institute of Medical Education and ResearchIndia 47.59.4%10.0×12 +106.0%
5 Semmelweis UniversityHungary 45.815.0%15.0×11 +1.1%
6 Medical University of WarsawPoland 39.87.1%10.0×8 +119.8%
7 McMaster UniversityCanada 38.723.1%5.0×10 +58.5%
8 Medical University of ViennaAustria 36.914.5%8.1×9 -25.1%
9 Nara Medical UniversityJapan 32.08.8%35.8×9 -6.0%
10 University of California San DiegoUnited States 31.824.8%3.4×11 +14.0%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Coagulation, Bradykinin, Polyphosphates, and Angioedema research growing?

Output in 2018–2022 was 17% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Coagulation, Bradykinin, Polyphosphates, and Angioedema.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.