Most cited papers in Coagulation, Bradykinin, Polyphosphates, and Angioedema
What are the most cited papers in Coagulation, Bradykinin, Polyphosphates, and Angioedema?
The most cited paper in Coagulation, Bradykinin, Polyphosphates, and Angioedema is "TOR Signaling in Growth and Metabolism" (Stephan Wullschleger, Robbie Loewith, Michael N. Hall, 2006), with 5,827 citations. Next come "A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9" (3,177) and "A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis" (3,128).
Showing 50 of 98 papers. Every paper with more than 835 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | TOR Signaling in Growth and Metabolism Stephan Wullschleger, Robbie Loewith, Michael N. Hall · Cell | Feb 2006 | 5,827 |
| 2 | A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9 Mary Donoghue, F. Hsieh, Elizabeth Baronas et al. · Circulation Research | Sep 2000 | 3,177 |
| 3 | A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis SR Poort, FR Rosendaal, PH Reitsma et al. · Blood | 15 Nov 1996 | 3,128 |
| 4 | Complement Mark J. Walport · New England Journal of Medicine | 5 Apr 2001 | 2,952 |
| 5 | Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton Dos D. Sarbassov, Siraj Mahamed Ali, Do‐Hyung Kim et al. · Current Biology | Jul 2004 | 2,701 |
| 6 | Thrombin signalling and protease-activated receptors Shaun R. Coughlin · Nature | Sep 2000 | 2,497 |
| 7 | Rho GTPases and signaling networks Linda Van Aelst, Crislyn D’Souza‐Schorey · Genes & Development | 15 Sep 1997 | 2,385 |
| 8 | Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF Pamela J. Keck, Scott D. Hauser, Gwen G. Krivi et al. · Science | 8 Dec 1989 | 2,077 |
| 9 | Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms Thorsten Klampfl et al. · New England Journal of Medicine | 10 Dec 2013 | 2,021 |
| 10 | Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Björn Dahlbäck, Martin Carlsson, Peter J. Svensson · Proceedings of the National Academy of Sciences | Feb 1993 | 1,990 |
| 11 | Mechanisms of Thrombus Formation Bruce Furie, Barbara C. Furie · New England Journal of Medicine | 27 Aug 2008 | 1,925 |
| 12 | The coagulation cascade: initiation, maintenance, and regulation Earl W. Davie, Kazuo Fujikawa, Walter Kisiel · Biochemistry | Oct 1991 | 1,823 |
| 13 | Acromegaly: An Endocrine Society Clinical Practice Guideline Laurence J. Katznelson, Edward R. Laws, Shlomo K. Melmed et al. · The Journal of Clinical Endocrinology & Metabolism | 30 Oct 2014 | 1,816 |
| 14 | Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura Gallia G. Levy, William C. Nichols, Eric C.‐Y. Lian et al. · Nature | 4 Oct 2001 | 1,764 |
| 15 | Bioregulation of kinins: kallikreins, kininogens, and kininases. K. D. Bhoola, Carlos D. Figueroa, Katrina H. Worthy · Pharmacological Reviews | Mar 1992 | 1,756 |
| 16 | Polypeptide with Broad Biological Activity: Isolation from Small Intestine Sami I. Said, Viktor Mutt · Science | 18 Sep 1970 | 1,603 |
| 17 | Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone Carsten Jonat, Hans J. Rahmsdorf, Kun-Koo Park et al. · Cell | Sep 1990 | 1,600 |
| 18 | Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome Christophe M. Legendre et al. · New England Journal of Medicine | 5 Jun 2013 | 1,590 |
| 19 | Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction Hsin‐Fang Yang‐Yen, Jean‐Claude Chambard, Yu-Lin Sun et al. · Cell | Sep 1990 | 1,589 |
| 20 | Venous thrombosis: a multicausal disease FR Rosendaal · The Lancet | Apr 1999 | 1,583 |
| 21 | The urokinase-type plasminogen activator system in cancer metastasis: A review Peter A. Andreasen, Lars Kjøller, Lise Christensen et al. · International Journal of Cancer | 3 Jul 1997 | 1,560 |
| 22 | The Pharmacology and Management of the Vitamin K Antagonists Jack Ansell, Jack Hirsh, Leon Poller et al. · CHEST Journal | Sep 2004 | 1,536 |
| 23 | STUDIES ON INFLAMMATION Guido Majno, George E. Palade · The Journal of Cell Biology | Dec 1961 | 1,531 |
| 24 | Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1 Kimberly A. McAllister, K.M. Grogg, David Wayne Johnson et al. · Nature Genetics | Dec 1994 | 1,507 |
| 25 | Regulation of matrix metalloproteinase expression in tumor invasion Jukka K. Westermarck, Veli‐Matti Kähäri · The FASEB Journal | May 1999 | 1,501 |
| 26 | ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM Marek Witold Radomski, Richard M. J. Palmer, Salvador Moncada · The Lancet | Nov 1987 | 1,449 |
| 27 | Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis Morie Abraham Gertz, Ray Comenzo, Rodney H. Falk et al. · American Journal of Hematology | 2005 | 1,438 |
| 28 | Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling Xiaofeng Li, Yazhou Zhang, Heeseog Kang et al. · Journal of Biological Chemistry | 19 Mar 2005 | 1,376 |
| 29 | Polymyalgia Rheumatica and Giant-Cell Arteritis Carlo Salvarani, Fabrizio Cantini, Luigi Boiardi et al. · New England Journal of Medicine | 25 Jul 2002 | 1,349 |
| 30 | Modulation of endothelial cell hemostatic properties by tumor necrosis factor. Peter P. Nawroth, D Stern · The Journal of Experimental Medicine | Mar 1986 | 1,324 |
| 31 | Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells ERIC A. JAFFE, Leon W. Hoyer, Ralph L. Nachman · Journal of Clinical Investigation | Nov 1973 | 1,292 |
| 32 | Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin Geneviève Nguyen, Françoise Delarue, Céline Burcklé et al. · Journal of Clinical Investigation | Jun 2002 | 1,282 |
| 33 | Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study Ted Koster, Jan Paul Vandenbroucke, FR Rosendaal et al. · The Lancet | Dec 1993 | 1,268 |
| 34 | 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides Kallenberg, C. G.M. et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill) | Nov 2020 | 1,268 |
| 35 | The molecular basis of blood coagulation Bruce Furie, Barbara C. Furie · Cell | May 1988 | 1,254 |
| 36 | The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria Torsten Zuberbier et al. · Allergy | 18 Sep 2021 | 1,253 |
| 37 | Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases Steffen Maßberg, Lenka Grahl, Marie‐Luise von Bruehl et al. · Nature Medicine | Aug 2010 | 1,220 |
| 38 | EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis Max M. Yates et al. · Annals of the Rheumatic Diseases | 24 Jun 2016 | 1,210 |
| 39 | LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS Jacques Benveniste, Peter M. Henson, Charles G. Cochrane · The Journal of Experimental Medicine | Dec 1972 | 1,208 |
| 40 | Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Thomas A. Drake, James H. Morrissey, Thomas S. Edgington · PubMed | May 1989 | 1,199 |
| 41 | International consensus guidance for management of myasthenia gravis Donald B. Sanders, Gil I. Wolfe, Michael G Benatar et al. · Neurology | 29 Jun 2016 | 1,190 |
| 42 | Metalloproteinase inhibitors: biological actions and therapeutic opportunities Andrew Howard Baker, Dylan R. Edwards, Gillian Murphy · Journal of Cell Science | Oct 2002 | 1,184 |
| 43 | Proteinase-activated Receptors Scott R. Macfarlane, Michael J. Seatter, Toru Kanke et al. | 10 Jul 2006 | 1,141 |
| 44 | Resistance to Activated Protein C as a Basis for Venous Thrombosis Peter J. Svensson, Björn Dahlbäck · New England Journal of Medicine | 24 Feb 1994 | 1,130 |
| 45 | New Fundamentals in Hemostasis Henri H. Versteeg, Johan W. M. Heemskerk, Marcel M Levi et al. · Physiological Reviews | 2013 | 1,126 |
| 46 | Inorganic Polyphosphate: A Molecule of Many Functions Arthur Kornberg, Narayana N. Rao, Dana Ault-Riché · Annual Review of Biochemistry | Jun 1999 | 1,120 |
| 47 | Rational design and characterization of a Rac GTPase-specific small molecule inhibitor Yuan Gao, J. Bradley Dickerson, Fukun Guo et al. · Proceedings of the National Academy of Sciences | 5 May 2004 | 1,120 |
| 48 | A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets Fiona Francis et al. · Nature Genetics | Oct 1995 | 1,118 |
| 49 | A Mutation in the TRPC6 Cation Channel Causes Familial Focal Segmental Glomerulosclerosis Michelle P. Winn, Peter J. Conlon, Kelvin L. Lynn et al. · Science | 6 May 2005 | 1,106 |
| 50 | Omalizumab for the Treatment of Chronic Idiopathic or Spontaneous Urticaria Marcus Maurer, Karin E. Rosén, Hsin-Ju Hsieh et al. · New England Journal of Medicine | 24 Feb 2013 | 1,105 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.