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Topic · Genetics

Neurogenetic and Muscular Disorders Research

Neurogenetic and Muscular Disorders Research is a research topic within Genetics. Science Explorer counts 25k research works in it since 1950. 15.4% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the gene therapy, molecular genetics, and clinical management of Spinal Muscular Atrophy (SMA). It covers topics such as SMN1 and SMN2 genes, Nusinersen treatment, antisense oligonucleotide therapies, motor neuron pathology, and the role of survival motor neuron protein in SMA. The cluster also discusses potential therapeutic strategies, including gene replacement therapy and the use of small molecules to modulate SMN expression.

  • Spinal Muscular Atrophy
  • SMN1
  • Nusinersen
  • Gene Replacement Therapy
  • Motor Neuron
  • SMN2
  • Antisense Oligonucleotides
  • Neuromuscular Junction
  • Survival Motor Neuron Protein
  • Clinical Management
Research works
25k
fractional, since 1950
In the world top 10%
3.9k
per year above
Top-10% rate
15.4%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+31%
the tick is no change

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Neurogenetic and Muscular Disorders Research research?

By volume, the United States and China publish the most (1.1k and 460 works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 1.1k works
  2. 2 China 460 works
  3. 3 United Kingdom 309 works
  4. 4 Italy 291 works
  5. 5 India 221 works
  6. 6 Germany 215 works
  7. 7 Japan 207 works
  8. 8 France 170 works
  9. 9 Brazil 144 works
  10. 10 Canada 144 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 33.2%China: 14.2%United Kingdom: 9.6%Italy: 9.0%6 others listed: 34.0%33%largest
United States1,071 · 33.2%China460 · 14.2%United Kingdom309 · 9.6%Italy291 · 9.0%6 others listed1,100 · 34.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Neurogenetic and Muscular Disorders Research research?

By volume in 2022–2025, University College London publishes the most Neurogenetic and Muscular Disorders Research research, followed by Inserm and University Medical Center Utrecht.

Who are the leading researchers in Neurogenetic and Muscular Disorders Research?

The most-cited researchers publishing on Neurogenetic and Muscular Disorders Research include Ettore Beghi.

  1. 1 Ettore Beghi Italy 4.6k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is Neurogenetic and Muscular Disorders Research research done?

The largest centres of Neurogenetic and Muscular Disorders Research research in 2022–2025 are London (United Kingdom), Beijing (China), Paris (France) and Tokyo (Japan). Among places with at least 20 works in it, it is an unusually large share of all research in Basel, Sheffield and Utrecht.

Largest cities, 2022–2025

  1. 1 London United Kingdom 122 works
  2. 2 Beijing China 87 works
  3. 3 Paris France 79 works
  4. 4 Tokyo Japan 65 works
  5. 5 Milan Italy 60 works
  6. 6 Rome Italy 55 works
  7. 7 New York United States 55 works
  8. 8 Boston United States 47 works
  9. 9 Seoul South Korea 45 works
  10. 10 Shanghai China 39 works

Where it is the local speciality

  1. BaselCH · 21.3 works7.5×
  2. SheffieldGB · 22.3 works7.0×
  3. UtrechtNL · 26.4 works5.2×
← less than its size predictsmore →

Location quotient: how much more of its research is in Neurogenetic and Muscular Disorders Research than the world average.

See Neurogenetic and Muscular Disorders Research on the map

Where is the best place to study Neurogenetic and Muscular Disorders Research?

Among universities, judged by research, University of Massachusetts Chan Medical School, University of Sheffield and University College London score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 29.64%fractional works in this node (log) →share in the world top 10% →University of Massachusetts Chan Medical School: 9, 40.6%University of Sheffield: 15, 33.1%University College London: 30, 22.3%KU Leuven: 13, 34.8%Harvard University: 13, 32.9%Johns Hopkins University: 12, 36.4%University of Oxford: 13, 29.1%University of Milan: 11, 26.8%Washington University in St. Louis: 13, 20.9%Sichuan University: 11, 19.5%University of Massac…KU LeuvenUniversity of Sheffi…University College L…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 University of Massachusetts Chan Medical SchoolUnited States 59.940.6%12.6×9 +4.4%
2 University of SheffieldUnited Kingdom 58.133.1%6.5×15 +46.2%
3 University College LondonUnited Kingdom 57.522.3%4.9×30 +38.7%
4 KU LeuvenBelgium 50.234.8%3.3×13 +49.1%
5 Harvard UniversityUnited States 43.732.9%2.4×13 +25.2%
6 Johns Hopkins UniversityUnited States 41.536.4%2.5×12 -4.4%
7 University of OxfordUnited Kingdom 39.029.1%2.3×13 -6.2%
8 University of MilanItaly 37.326.8%3.7×11 +7.3%
9 Washington University in St. LouisUnited States 36.320.9%4.2×13 +22.7%
10 Sichuan UniversityChina 33.319.5%1.4×11 +144.9%

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is Neurogenetic and Muscular Disorders Research research growing?

Output in 2018–2022 was 31% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are Neurogenetic and Muscular Disorders Research.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.