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Topic · Genetics

Mesenchymal stem cell research

Mesenchymal stem cell research is a research topic within Genetics. Science Explorer counts 43k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the research and applications of multipotent mesenchymal stem cells, particularly in the areas of regeneration, immunomodulation, therapeutic interventions, differentiation potential, isolation techniques, transplantation procedures, and their role in cardiac repair. The papers cover a wide range of topics related to the properties and potential uses of mesenchymal stem cells in various medical contexts.

  • Mesenchymal Stem Cells
  • Multipotent
  • Regeneration
  • Immunomodulation
  • Therapeutic
  • Differentiation
  • Isolation
  • Transplantation
  • Cardiac Repair
  • Stromal Cells
Research works
43k
fractional, since 1950
In the world top 10%
4.2k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-8%
the tick is no change
Largest producer
China
40% of the 10 largest, 2022-now
Mesenchymal stem cell research

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Mesenchymal stem cell research research?

By volume, China and the United States publish the most (2.4k and 1.3k works in 2022-now).

By volume, 2022-now

  1. 1 China 2.4k works
  2. 2 United States 1.3k works
  3. 3 Japan 418 works
  4. 4 Iran 392 works
  5. 5 India 320 works
  6. 6 South Korea 294 works
  7. 7 Italy 269 works
  8. 8 Germany 231 works
  9. 9 Brazil 209 works
  10. 10 United Kingdom 192 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

China: 40.1%United States: 21.4%Japan: 6.9%Iran: 6.5%6 others listed: 25.1%40%largest
China2,424 · 40.1%United States1,294 · 21.4%Japan418 · 6.9%Iran392 · 6.5%6 others listed1,515 · 25.1%

Shares of the rows listed above, not of the whole node.

Which institutions lead Mesenchymal stem cell research research?

By volume in 2022-now, Sichuan University publishes the most Mesenchymal stem cell research research, followed by Shanghai Jiao Tong University and Southern Medical University.

By volume, 2022-now

  1. 1 Sichuan UniversityChina 84 works
  2. 2 Shanghai Jiao Tong UniversityChina 72 works
  3. 3 Southern Medical UniversityChina 64 works
  4. 4 Sun Yat-sen UniversityChina 63 works
  5. 5 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 58 works
  6. 6 Zhejiang UniversityChina 53 works
  7. 7 Harvard UniversityUnited States 52 works
  8. 8 Russian Academy of SciencesRussia 47 works
  9. 9 Peking UniversityChina 43 works
  10. 10 Tehran University of Medical SciencesIran 41 works

Who are the leading researchers in Mesenchymal stem cell research?

The most-cited researchers publishing on Mesenchymal stem cell research include David Moher, Shizuo Akira and Cyrus Cooper.

  1. 1 David Moher Canada 898k citations
  2. 2 Shizuo Akira Japan 342k citations
  3. 3 Cyrus Cooper United Kingdom 342k citations
  4. 4 Jun Wang China 340k citations
  5. 5 Stephan Windecker Switzerland 338k citations
  6. 6 Giuseppe Remuzzi Italy 328k citations
  7. 7 Róbert Langer United States 303k citations
  8. 8 Robert A. Weinberg United States 301k citations
  9. 9 Todd R. Golub United States 283k citations
  10. 10 Jeremy Grimshaw Canada 281k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Mesenchymal stem cell research?

The most cited paper in Mesenchymal stem cell research is "Multilineage Potential of Adult Human Mesenchymal Stem Cells" (Mark F. Pittenger, Alastair M. Mackay, Stephen C. Beck et al., 1999), with 21,222 citations. Next come "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors" (20,424) and "Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement" (18,014).

Most cited papers
#PaperReleasedCitations
1 Multilineage Potential of Adult Human Mesenchymal Stem Cells Mark F. Pittenger, Alastair M. Mackay, Stephen C. Beck et al. · Science 2 Apr 1999 21,222
2 Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell Nov 2007 20,424
3 Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement Massimo Dominici, Katarina Le Blanc, Ingo Mueller et al. · Cytotherapy 2006 18,014
4 Embryonic Stem Cell Lines Derived from Human Blastocysts James Alexander Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science 6 Nov 1998 16,067
5 The basics of epithelial-mesenchymal transition Raghu K. Kalluri, Robert A. Weinberg · Journal of Clinical Investigation Open access Jun 2009 10,281
All 99 most cited papers, with filters and sorting

Where is Mesenchymal stem cell research research done?

The largest centres of Mesenchymal stem cell research research in 2022-now are Beijing (China), Shanghai (China), Guangzhou (China) and Tehran (Iran). Among places with at least 20 works in it, it is an unusually large share of all research in Zunyi and Galway.

Largest cities, 2022-now

  1. 1 BeijingChina 303 works
  2. 2 ShanghaiChina 207 works
  3. 3 GuangzhouChina 197 works
  4. 4 TehranIran 182 works
  5. 5 SeoulSouth Korea 153 works
  6. 6 TokyoJapan 119 works
  7. 7 MoscowRussia 112 works
  8. 8 HangzhouChina 104 works
  9. 9 Xi'anChina 103 works
  10. 10 ChengduChina 99 works

Where it is the local speciality

  1. ZunyiCN · 21.3 works12×
  2. GalwayIE · 21.6 works11×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Mesenchymal stem cell research than the world average.

See Mesenchymal stem cell research on the map

Where is the best place to study Mesenchymal stem cell research?

Among universities, judged by research, Sichuan University, Harvard University and Wuhan University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%10%20%mean 18.61%fractional works in this field (log) →share of work in the world top 10% →Wuhan UniversitySichuan UniversityHarvard UniversitySouthern Medical Uni…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Sichuan UniversityChina 78.921.0%5.1×84 +0.3%
2Harvard UniversityUnited States 70.815.0%2.2×52 -0.4%
3Wuhan UniversityChina 69.621.9%3.0×32 +63.2%
4Southern Medical UniversityChina 68.414.5%14.2×64 +12.6%
5Shanghai Jiao Tong UniversityChina 67.917.6%3.4×72 -13.1%
6Soochow UniversityChina 67.721.6%4.3×30 +11.7%
7Huazhong University of Science and TechnologyChina 64.623.1%2.4×31 +11.9%
8Peking UniversityChina 64.316.9%2.9×43 +6.0%
9Zhejiang UniversityChina 64.017.7%2.7×53 -17.7%
10Stanford UniversityUnited States 63.816.8%3.2×34 -27.2%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Mesenchymal stem cell research, country by country

Is Mesenchymal stem cell research research growing?

Output in 2022-2025 was 8% lower than in 2018-2021, peaking in 2014.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Mesenchymal stem cell research as a percentage of every work published that year, 0.034% in 2024.

still counting0.020%0.040%0.060%Mesenchymal stem cell research0.034% in 202519801990200020102020

Fractional works of Mesenchymal stem cell research over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Mesenchymal stem cell research10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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