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Topic · Oncology

CAR-T cell therapy research

CAR-T cell therapy research is a research topic within Oncology. Science Explorer counts 48k research works in it since 1950. 22.7% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on Chimeric Antigen Receptor (CAR) T cell therapy, a form of immunotherapy that uses genetically engineered T cells to target and destroy cancer cells. The papers cover various aspects of CAR T cell therapy, including its application in treating leukemia, lymphoma, and solid tumors, the management of cytokine release syndrome associated with this therapy, and the long-term efficacy and safety of CAR T cell treatment.

  • CAR T Cells
  • Chimeric Antigen Receptor
  • T Cell Therapy
  • Leukemia
  • Lymphoma
  • Immunotherapy
  • Cytokine Release Syndrome
  • Tumor Regression
  • Adoptive Cell Transfer
  • Cancer Immunotherapy
Research works
48k
fractional, since 1950
In the world top 10%
11k
per year above
Top-10% rate
22.7%
share of its works in the world top 10%
Growth, 2013–17 → 2018–22
+109%
the tick is no change

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead CAR-T cell therapy research research?

By volume, the United States and China publish the most (6.4k and 2.6k works in 2022–2025).

By volume, 2022–2025

  1. 1 United States 6.4k works
  2. 2 China 2.6k works
  3. 3 Germany 855 works
  4. 4 United Kingdom 569 works
  5. 5 Japan 507 works
  6. 6 France 492 works
  7. 7 Italy 455 works
  8. 8 Spain 409 works
  9. 9 Canada 326 works
  10. 10 India 299 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 49.4%China: 20.3%Germany: 6.6%United Kingdom: 4.4%6 others listed: 19.2%49%largest
United States6,398 · 49.4%China2,632 · 20.3%Germany855 · 6.6%United Kingdom569 · 4.4%6 others listed2,488 · 19.2%

Shares of the rows listed above, not of the whole node.

Which institutions lead CAR-T cell therapy research research?

By volume in 2022–2025, The University of Texas MD Anderson Cancer Center publishes the most CAR-T cell therapy research research, followed by University of Pennsylvania and Memorial Sloan Kettering Cancer Center.

By volume, 2022–2025

  1. 1 The University of Texas MD Anderson Cancer CenterUnited States 248 works
  2. 2 University of PennsylvaniaUnited States 149 works
  3. 3 Memorial Sloan Kettering Cancer CenterUnited States 143 works
  4. 4 Moffitt Cancer CenterUnited States 116 works
  5. 5 Stanford UniversityUnited States 93 works
  6. 6 Dana-Farber Cancer InstituteUnited States 87 works
  7. 7 Harvard UniversityUnited States 84 works
  8. 8 University of North Carolina at Chapel HillUnited States 75 works
  9. 9 Massachusetts General HospitalUnited States 74 works
  10. 10 Fred Hutch Cancer CenterUnited States 73 works

Who are the leading researchers in CAR-T cell therapy research?

The most-cited researchers publishing on CAR-T cell therapy research include Gad Getz, Matthias Mann and Dirk Schadendorf.

  1. 1 Gad Getz United States 6.2k citations
  2. 2 Matthias Mann Germany 5.1k citations
  3. 3 Dirk Schadendorf Germany 4.4k citations
  4. 4 Guido Kroemer France 4.2k citations
  5. 5 Hagop M. Kantarjian United States 4k citations
  6. 6 Julie R. Brahmer United States 3.8k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

Where is CAR-T cell therapy research research done?

The largest centres of CAR-T cell therapy research research in 2022–2025 are Beijing (China), New York (United States), Houston (United States) and Shanghai (China). Among places with at least 20 works in it, it is an unusually large share of all research in South San Francisco, Duarte and Lancaster.

Largest cities, 2022–2025

  1. 1 Beijing China 435 works
  2. 2 New York United States 381 works
  3. 3 Houston United States 360 works
  4. 4 Shanghai China 302 works
  5. 5 Philadelphia United States 287 works
  6. 6 Boston United States 273 works
  7. 7 London United Kingdom 247 works
  8. 8 Paris France 200 works
  9. 9 Seattle United States 195 works
  10. 10 Guangzhou China 180 works

Where it is the local speciality

  1. South San FranciscoUS · 50.4 works75×
  2. DuarteUS · 55.9 works66×
  3. LancasterUS · 70.9 works60×
← less than its size predicts1×more →

Location quotient: how much more of its research is in CAR-T cell therapy research than the world average.

See CAR-T cell therapy research on the map

Where is the best place to study CAR-T cell therapy research?

Among universities, judged by research, University of Pennsylvania, Oncode Institute and Xuzhou Medical College score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%60%mean 30.46%fractional works in this node (log) →share in the world top 10% →University of Pennsylvania: 149, 25.0%Oncode Institute: 11, 49.0%Xuzhou Medical College: 30, 31.1%Medical College of Wisconsin: 44, 23.3%China Pharmaceutical University: 21, 37.5%University of California, San Francisco: 59, 22.9%Institute of Cancer Research: 10, 24.4%Harvard University: 84, 32.9%Chinese Academy of Medical Sciences & Peking Union Medical College: 68, 24.2%Navarre Institute of Health Research: 8, 34.3%Oncode InstituteXuzhou Medical CollegeUniversity of Pennsy…Medical College of W…
above the meannear itbelow it

One dot per university in the table below. The upper left is the interesting corner: small places doing unusually strong work.

#UniversityScoreTop 10%SpecialisationWorksGrowth
1 University of PennsylvaniaUnited States 68.625.0%10.9×149 +157.3%
2 Oncode InstituteNetherlands 64.549.0%26.2×11 +90.5%
3 Xuzhou Medical CollegeChina 62.831.1%9.7×30 +356.3%
4 Medical College of WisconsinUnited States 62.423.3%11.6×44 +371.7%
5 China Pharmaceutical UniversityChina 55.837.5%6.5×21 +267.6%
6 University of California, San FranciscoUnited States 54.222.9%6.3×59 +177.1%
7 Institute of Cancer ResearchUnited Kingdom 53.924.4%20.2×10 +128.0%
8 Harvard UniversityUnited States 53.232.9%4.5×84 +100.5%
9 Chinese Academy of Medical Sciences & Peking Union Medical CollegeChina 52.124.2%4.8×68 +200.8%
10 Navarre Institute of Health ResearchSpain 52.134.3%23.4×8 —

Universities only. Score blends excellence (30%), specialisation (25%), size (20%), growth (15%) and international reach (10%), 2015–2022; growth compares 2010–14 with 2015–19.

Is CAR-T cell therapy research research growing?

Output in 2018–2022 was 109% higher than in 2013–2017, peaking in 2025. The fastest-growing topics are CAR-T cell therapy research.

19801990200020102020
grewheldshrank

The same series as a ribbon — one cell per year, darker for more. The line above answers how much; this answers when.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.