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Topic · Oncology

Metal complexes synthesis and properties

Metal complexes synthesis and properties is a research topic within Oncology. Science Explorer counts 70k research works in it since 1950. 9.8% of them reached the world's top 10% most cited for their field and year.

This cluster of papers explores the advancements and challenges in platinum-based cancer chemotherapy, focusing on the molecular mechanisms of action, resistance, and toxicity associated with platinum drugs. It also delves into the development of new metal complexes as potential therapeutics, DNA interactions of metal compounds, and the exploration of ruthenium compounds as anticancer agents.

  • Platinum-Based Drugs
  • Cisplatin Resistance
  • Metal Complexes
  • Anticancer Agents
  • Molecular Mechanisms
  • DNA Interactions
  • Ruthenium Compounds
  • Chemical Biology
  • Drug Development
  • Cellular Processing
Research works
70k
fractional, since 1950
In the world top 10%
6.8k
per year above
Top-10% rate
9.8%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-9%
the tick is no change
Largest producer
India
37% of the 10 largest, 2022-now
Metal complexes synthesis and properties

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Metal complexes synthesis and properties research?

By volume, India and China publish the most (1.7k and 954 works in 2022-now).

By volume, 2022-now

  1. 1 India 1.7k works
  2. 2 China 954 works
  3. 3 United States 410 works
  4. 4 Russia 353 works
  5. 5 Türkiye 314 works
  6. 6 Egypt 215 works
  7. 7 Germany 199 works
  8. 8 Saudi Arabia 194 works
  9. 9 Iraq 192 works
  10. 10 France 166 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

India: 36.7%China: 20.1%United States: 8.6%Russia: 7.5%6 others listed: 27.0%37%largest
India1,740 · 36.7%China954 · 20.1%United States410 · 8.6%Russia353 · 7.5%6 others listed1,279 · 27.0%

Shares of the rows listed above, not of the whole node.

Which institutions lead Metal complexes synthesis and properties research?

By volume in 2022-now, University of Rajasthan publishes the most Metal complexes synthesis and properties research, followed by Central University of Rajasthan and Russian Academy of Sciences.

Who are the leading researchers in Metal complexes synthesis and properties?

The most-cited researchers publishing on Metal complexes synthesis and properties include Michaël Grätzel, George Davey Smith and Guido Kroemer.

  1. 1 Michaël Grätzel Switzerland 458k citations
  2. 2 George Davey Smith United Kingdom 435k citations
  3. 3 Guido Kroemer France 386k citations
  4. 4 Michael Karin United States 276k citations
  5. 5 George M. Whitesides United States 267k citations
  6. 6 Wei Huang China 267k citations
  7. 7 Ben Zhong Tang China 261k citations
  8. 8 Ralph B. D’Agostino United States 255k citations
  9. 9 Omar M. Yaghi United States 254k citations
  10. 10 Richard Anthony Flavell United States 237k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Metal complexes synthesis and properties?

The most cited paper in Metal complexes synthesis and properties is "Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review" (Hiroshi Maeda, Jun Wu, Tomohiro Sawa et al., 2000), with 6,577 citations. Next come "Cisplatin in cancer therapy: Molecular mechanisms of action" (5,600) and "Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies" (5,252).

Most cited papers
#PaperReleasedCitations
1 Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review Hiroshi Maeda, Jun Wu, Tomohiro Sawa et al. · Journal of Controlled Release Mar 2000 6,577
2 Cisplatin in cancer therapy: Molecular mechanisms of action Shaloam R. Dasari, Paul Bernard Tchounwou · European Journal of Pharmacology Open access 21 Jul 2014 5,600
3 Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies Ting‐Chao Chou · Pharmacological Reviews Sep 2006 5,252
4 Relationships between the carbon-oxygen stretching frequencies of carboxylato complexes and the type of carboxylate coordination Glen B. Deacon · Coordination Chemistry Reviews Oct 1980 5,123
5 Introduction and General Overview of Cyclodextrin Chemistry József Szejtli · Chemical Reviews Review 9 Jun 1998 4,994
All 100 most cited papers, with filters and sorting

Where is Metal complexes synthesis and properties research done?

The largest centres of Metal complexes synthesis and properties research in 2022-now are Jaipur (India), Ajmer (India), Moscow (Russia) and Kolkata (India). Among places with at least 20 works in it, it is an unusually large share of all research in Ajmer, Jaipur and Sohag.

Largest cities, 2022-now

  1. 1 JaipurIndia 303 works
  2. 2 AjmerIndia 278 works
  3. 3 MoscowRussia 123 works
  4. 4 KolkataIndia 75 works
  5. 5 NovosibirskRussia 72 works
  6. 6 BeijingChina 72 works
  7. 7 BaghdadIraq 70 works
  8. 8 RiyadhSaudi Arabia 67 works
  9. 9 ParisFrance 65 works
  10. 10 ChennaiIndia 63 works

Where it is the local speciality

  1. AjmerIN · 278.4 works165×
  2. JaipurIN · 303.4 works48×
  3. SohagEG · 20.7 works25×
  4. KragujevacRS · 21.5 works25×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Metal complexes synthesis and properties than the world average.

See Metal complexes synthesis and properties on the map

Where is the best place to study Metal complexes synthesis and properties?

Among universities, judged by research, Guru Jambheshwar University of Science and Technology, Sohag University and King Faisal University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%25%50%75%mean 36.09%fractional works in this field (log) →share of work in the world top 10% →Guru Jambheshwar Uni…Sohag UniversityTaibah UniversityKing Faisal University
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Guru Jambheshwar University of Science and TechnologyIndia 65.963.3%39.8×16 +187.8%
2Sohag UniversityEgypt 65.048.8%27.8×21 +220.5%
3King Faisal UniversitySaudi Arabia 55.734.3%10.9×16 +283.5%
4Taibah UniversitySaudi Arabia 54.045.7%9.4×9 +25.7%
5Lanzhou Jiaotong UniversityChina 52.558.3%24.5×34 -36.2%
6King Saud UniversitySaudi Arabia 48.715.8%6.4×38 +25.3%
7Saveetha UniversityIndia 48.235.1%3.0×18 +454.7%
8Damietta UniversityEgypt 47.632.5%21.1×11 +12.9%
9Vellore Institute of Technology UniversityIndia 47.526.9%5.8×34 +167.4%
10University of RajasthanIndia 47.40.2%361.3×293 +8.1%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Metal complexes synthesis and properties, country by country

Is Metal complexes synthesis and properties research growing?

Output in 2022-2025 was 9% lower than in 2018-2021, peaking in 2012.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Metal complexes synthesis and properties as a percentage of every work published that year, 0.026% in 2024.

still counting0.10%0.20%Metal complexes synthesis and properties0.023% in 202519801990200020102020

Fractional works of Metal complexes synthesis and properties over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Metal complexes synthesis and properties10.0% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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