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Most cited papers in Metal complexes synthesis and properties

Metal complexes synthesis and properties

What are the most cited papers in Metal complexes synthesis and properties?

The most cited paper in Metal complexes synthesis and properties is "Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review" (Hiroshi Maeda, Jun Wu, Tomohiro Sawa et al., 2000), with 6,577 citations. Next come "Cisplatin in cancer therapy: Molecular mechanisms of action" (5,600) and "Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies" (5,252).

Showing 50 of 100 papers. Every paper with more than 927 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review Hiroshi Maeda, Jun Wu, Tomohiro Sawa et al. · Journal of Controlled Release Mar 2000 6,577
2 Cisplatin in cancer therapy: Molecular mechanisms of action Shaloam R. Dasari, Paul Bernard Tchounwou · European Journal of Pharmacology Open access 21 Jul 2014 5,600
3 Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies Ting‐Chao Chou · Pharmacological Reviews Sep 2006 5,252
4 Relationships between the carbon-oxygen stretching frequencies of carboxylato complexes and the type of carboxylate coordination Glen B. Deacon · Coordination Chemistry Reviews Oct 1980 5,123
5 Introduction and General Overview of Cyclodextrin Chemistry József Szejtli · Chemical Reviews Review 9 Jun 1998 4,994
6 A simple, rapid, and sensitive DNA assay procedure Cesar G. Labarca, Kenneth Paigen · Analytical Biochemistry Mar 1980 4,971
7 The resurgence of platinum-based cancer chemotherapy Lloyd R. Kèlland · Nature reviews. Cancer Review 12 Jul 2007 4,748
8 Metal–Organic Frameworks in Biomedicine Patricia Horcajada, Ruxandra Gref, Tarek Baâti et al. · Chemical Reviews Review 14 Dec 2011 4,151
9 Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature Julius Marmur, Paul M. Doty · Journal of Molecular Biology Jul 1962 4,109
10 Platinum Compounds: a New Class of Potent Antitumour Agents Barnett Rosenberg, Loretta Vancamp, James Edward Trosko et al. · Nature Apr 1969 3,961
11 Cellular processing of platinum anticancer drugs Dong Wang, Stephen J. Lippard · Nature Reviews Drug Discovery Review 24 Mar 2005 3,802
12 The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect Jun Qun Fang, Hideaki Nakamura, Hiroshi Maeda · Advanced Drug Delivery Reviews Review 3 May 2010 3,563
13 Structural variation in copper( i ) complexes with pyridylmethylamide ligands: structural analysis with a new four-coordinate geometry index, τ 4 Lei Yang, Douglas R. Powell, Robert P. Houser · Dalton Transactions 2007 3,466
14 Cisplatin: mode of cytotoxic action and molecular basis of resistance Zahid Hussain Siddik · Oncogene 20 Oct 2003 3,351
15 Oxidative DNA damage: mechanisms, mutation, and disease Marcus S. Cooke, Mark Dennis Evans, Miral Dizdaroğlu et al. · The FASEB Journal Jul 2003 3,252
16 Enantioselective catalysis with homochiral metal–organic frameworks Liqing Ma, Carter W. Abney, Wenbin Lin · Chemical Society Reviews Review 2009 3,118
17 Theoretical aspects of DNA-protein interactions: Co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice James D. McGhee, Peter H. von Hippel · Journal of Molecular Biology Jun 1974 2,973
18 Metal–Organic Frameworks and Self-Assembled Supramolecular Coordination Complexes: Comparing and Contrasting the Design, Synthesis, and Functionality of Metal–Organic Materials Timothy R. Cook, Yao‐Rong Zheng, Peter J. Stang · Chemical Reviews ReviewOpen access 2 Nov 2012 2,956
19 Structure, Recognition, and Processing of Cisplatin−DNA Adducts Elizabeth R. Jamieson, Stephen J. Lippard · Chemical Reviews Review 14 Aug 1999 2,952
20 Applications of metal–organic frameworks in heterogeneous supramolecular catalysis Jiewei Liu, Lianfen Chen, Hao Cui et al. · Chemical Society Reviews Review 2014 2,900
21 Molecular mechanisms of cisplatin resistance Lorenzo Galluzzi, Laura Senovilla, Ilio Vitale et al. · Oncogene 5 Sep 2011 2,825
22 The electronic properties and stereochemistry of mono-nuclear complexes of the copper(II) ion B. J. Hathaway, D. E. Billing · Coordination Chemistry Reviews Jul 1970 2,677
23 ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS V. G. Allfrey, Robert D. Faulkner, A. E. Mirsky · Proceedings of the National Academy of Sciences Open access May 1964 2,629
24 Structural and Functional Aspects of Metal Sites in Biology R. H. Holm, Pierre Kennepohl, Edward I. Solomon · Chemical Reviews Review 1996 2,548
25 The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs Timothy C. Johnstone, Kogularamanan Suntharalingam, Stephen J. Lippard · Chemical Reviews ReviewOpen access 11 Feb 2016 2,494
26 The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting Hiroshi Maeda · Advances in Enzyme Regulation May 2001 2,494
27 Secondary building units, nets and bonding in the chemistry of metal–organic frameworks David J. Tranchemontagne, José L. Mendoza-Cortés, M. O’Keeffe et al. · Chemical Society Reviews Review 2009 2,488
28 Handbook of methods for oxygen radical research Robert A. Greenwald · Free Radical Biology and Medicine 1987 2,385
29 Cancer statistics, 1998 Sarah Landis, Thomas S. Murray, S. Bolden et al. · CA A Cancer Journal for Clinicians Open access 1998 2,384
30 Postsynthetic Methods for the Functionalization of Metal–Organic Frameworks Seth M. Cohen · Chemical Reviews Review 14 Sep 2011 2,343
31 A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies Debomoy K. Lahiri, John I. Numberger · Nucleic Acids Research Open access 1991 2,315
32 Rapid extraction of bacterial genomic DNA with guanidium thiocyanate D.G. Pitcher, Nicholas Andrew Saunders, Robert J. Owen · Letters in Applied Microbiology Apr 1989 2,175
33 Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase‐trimethoprim, a drug‐receptor system Pnina Dauber‐Osguthorpe, Victoria A. Roberts, David J. Osguthorpe et al. · Proteins Structure Function and Bioinformatics 1988 2,083
34 Zirconium‐Metalloporphyrin PCN‐222: Mesoporous Metal–Organic Frameworks with Ultrahigh Stability as Biomimetic Catalysts Dawei Feng, Zhi‐Yuan Gu, Jian‐Rong Li et al. · Angewandte Chemie International Edition 21 Aug 2012 1,979
35 Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding Stephen G. Aller, Jodie Yu, Andrew B. Ward et al. · Science Open access 26 Mar 2009 1,935
36 Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies Navjotsingh Pabla, Zheng Dong · Kidney International Open access 13 Feb 2008 1,925
37 Metal–Organic Frameworks: Opportunities for Catalysis David Farrusseng, Sónia Aguado, Catherine Pinel · Angewandte Chemie International Edition 18 Aug 2009 1,889
38 Recognition and Reaction of Metallointercalators with DNA Kathryn E. Erkkila, Duncan T. Odom, Jacqueline K. Barton · Chemical Reviews Review 3 Aug 1999 1,871
39 Exploiting the enhanced permeability and retention effect for tumor targeting Arun K. Iyer, Khaled F. Greish, Jun Qun Fang et al. · Drug Discovery Today 26 Aug 2006 1,845
40 The structure of β-lactamases R P Ambler · Philosophical transactions of the Royal Society of London. Series B, Biological sciences 16 May 1980 1,834
41 The theory of transition-metal ions F.J. Donahoe · Journal of the Franklin Institute Oct 1961 1,830
42 Ligand‐Directed Strategy for Zeolite‐Type Metal–Organic Frameworks: Zinc( II ) Imidazolates with Unusual Zeolitic Topologies Xiao‐Chun Huang, Yan‐Yong Lin, Jie‐Peng Zhang et al. · Angewandte Chemie International Edition 27 Jan 2006 1,817
43 Advances in Copper Complexes as Anticancer Agents Carlo Santini, Maura Pellei, Valentina Gandin et al. · Chemical Reviews Review 8 Oct 2013 1,786
44 Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects Ana-Maria Florea, Dietrich Büsselberg · Cancers Open access 15 Mar 2011 1,785
45 Cisplatin: The first metal based anticancer drug Sumit Ghosh · Bioorganic Chemistry 11 Apr 2019 1,768
46 Copper Active Sites in Biology Edward I. Solomon, David E. Heppner, Esther M. Johnston et al. · Chemical Reviews ReviewOpen access 3 Mar 2014 1,761
47 The Mononuclear Molybdenum Enzymes Russ Hille, James E. Hall, Partha Basu · Chemical Reviews ReviewOpen access 28 Jan 2014 1,740
48 Isolation of High‐Molecular‐Weight DNA from Mammalian Cells M. Gross-Bellard, P Oudet, Pierre Chambon · European Journal of Biochemistry Jul 1973 1,709
49 Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes Matthew Eldridge, Christopher W. Murray, T.R. Auton et al. · Journal of Computer-Aided Molecular Design Sep 1997 1,694
50 Chemistry of Biologically Important Synthetic Organoselenium Compounds Govindasamy Mugesh, Wolf-Walther Du Μοnt, Helmut Sies · Chemical Reviews Review 13 Jun 2001 1,690

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for a field when OpenAlex files it under one of the field's topics; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.