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Topic · Oncology

Polyomavirus and related diseases

Polyomavirus and related diseases is a research topic within Oncology. Science Explorer counts 23k research works in it since 1950. 10.1% of them reached the world's top 10% most cited for their field and year.

This cluster of papers focuses on the association between polyomaviruses, particularly Merkel cell polyomavirus and JC virus, with the development of malignancies such as Merkel cell carcinoma and the manifestation of progressive multifocal leukoencephalopathy in immunocompromised individuals. It also explores the impact of immunosuppressive therapies, viral replication in renal transplant recipients, and the potential role of viral oncoproteins in promoting tumorigenesis.

  • Polyomavirus
  • Merkel Cell Carcinoma
  • Progressive Multifocal Leukoencephalopathy
  • Natalizumab
  • Renal Transplantation
  • T antigen mutations
  • Viral Oncoproteins
  • Immunosuppression
  • Viral Nephropathy
  • JC Virus
Research works
23k
fractional, since 1950
In the world top 10%
2.4k
per year above
Top-10% rate
10.1%
share of its works in the world top 10%
Growth, 2018-21 → 2022-25
-3%
the tick is no change
Largest producer
United States
45% of the 10 largest, 2022-now
Polyomavirus and related diseases

This ranks research output and citation impact. It says nothing about the quality of diagnosis, treatment or care.

Which countries lead Polyomavirus and related diseases research?

By volume, the United States and China publish the most (1.2k and 320 works in 2022-now).

By volume, 2022-now

  1. 1 United States 1.2k works
  2. 2 China 320 works
  3. 3 Japan 184 works
  4. 4 Italy 172 works
  5. 5 Germany 152 works
  6. 6 India 147 works
  7. 7 France 142 works
  8. 8 United Kingdom 120 works
  9. 9 Spain 107 works
  10. 10 Australia 79 works

How concentrated that is

The same countries as shares of everything the list above accounts for. A node where two countries do two thirds of the work and one spread evenly across twelve read alike as a ranking and not at all alike here.

United States: 45.4%China: 12.3%Japan: 7.1%Italy: 6.6%6 others listed: 28.7%45%largest
United States1,184 · 45.4%China320 · 12.3%Japan184 · 7.1%Italy172 · 6.6%6 others listed747 · 28.7%

Shares of the rows listed above, not of the whole node.

Which institutions lead Polyomavirus and related diseases research?

By volume in 2022-now, Harvard University publishes the most Polyomavirus and related diseases research, followed by National Institutes of Health and Mayo Clinic.

By volume, 2022-now

  1. 1 Harvard UniversityUnited States 50 works
  2. 2 National Institutes of HealthUnited States 31 works
  3. 3 Mayo ClinicUnited States 28 works
  4. 4 University of WashingtonUnited States 25 works
  5. 5 University of PennsylvaniaUnited States 23 works
  6. 6 The University of Texas MD Anderson Cancer CenterUnited States 22 works
  7. 7 Sun Yat-sen UniversityChina 19 works
  8. 8 Johns Hopkins UniversityUnited States 19 works
  9. 9 InsermFrance 19 works
  10. 10 Northwestern UniversityUnited States 18 works

Who are the leading researchers in Polyomavirus and related diseases?

The most-cited researchers publishing on Polyomavirus and related diseases include Hermann Brenner, Giuseppe Remuzzi and Matthias Egger.

  1. 1 Hermann Brenner Germany 343k citations
  2. 2 Giuseppe Remuzzi Italy 328k citations
  3. 3 Matthias Egger Switzerland 326k citations
  4. 4 Robert A. Weinberg United States 301k citations
  5. 5 Richard A. Gibbs United States 292k citations
  6. 6 Matthew M. Meyerson United States 280k citations

Ranked by citations received across their whole record, among researchers with at least three works on this topic.

What are the most cited papers in Polyomavirus and related diseases?

The most cited paper in Polyomavirus and related diseases is "Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review" (Rimda Wanchoo, Sabine Karam, Nupur N. Uppal et al., 2017), with 15,286 citations. Next come "Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures" (5,970) and "CLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S" (3,742).

Most cited papers
#PaperReleasedCitations
1 Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review Rimda Wanchoo, Sabine Karam, Nupur N. Uppal et al. · American Journal of Nephrology ReviewOpen access 2017 15,286
2 Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures Peter Pushko, Paul Pumpens, Elmars Grens · Intervirology Open access 2013 5,970
3 CLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S Harold Glucksberg, Rainer Storb, A Fefer et al. · Transplantation Oct 1974 3,742
4 Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma Huichen Feng, Masahiro Shuda, Yuan Chang et al. · Science Open access 17 Jan 2008 3,242
5 SV40-transformed simian cells support the replication of early SV40 mutants Yakov Gluzman · Cell 1981 2,472
All 99 most cited papers, with filters and sorting

Where is Polyomavirus and related diseases research done?

The largest centres of Polyomavirus and related diseases research in 2022-now are New York (United States), Beijing (China), Tokyo (Japan) and Paris (France). Among places with at least 20 works in it, it is an unusually large share of all research in Bethesda, Seattle and Cleveland.

Largest cities, 2022-now

  1. 1 New YorkUnited States 55 works
  2. 2 BeijingChina 51 works
  3. 3 TokyoJapan 51 works
  4. 4 ParisFrance 48 works
  5. 5 PhiladelphiaUnited States 48 works
  6. 6 SeattleUnited States 43 works
  7. 7 HoustonUnited States 42 works
  8. 8 BostonUnited States 42 works
  9. 9 LondonUnited Kingdom 41 works
  10. 10 RomeItaly 38 works

Where it is the local speciality

  1. BethesdaUS · 31.5 works7.4×
  2. SeattleUS · 42.6 works6.4×
  3. ClevelandUS · 28.7 works5.7×
← less than its size predicts1×more →

Location quotient: how much more of its research is in Polyomavirus and related diseases than the world average.

See Polyomavirus and related diseases on the map

Where is the best place to study Polyomavirus and related diseases?

Among universities, judged by research, Harvard University, University of Washington and Johns Hopkins University score highest, combining excellence, specialisation, size, growth and international reach. Research strength is one signal when choosing where to study; it does not measure teaching.

0%20%40%mean 18.85%fractional works in this field (log) →share of work in the world top 10% →Karolinska InstitutetJohns Hopkins Univer…Harvard UniversityUniversity of Washin…
above the meannear itbelow it

One dot per university in the first ten of the table below, at the default weights. The upper left is the interesting corner: small places doing unusually strong work.

Excellenceshare of its work in the world top 10%, 2022-now and all time averaged
40%
Specialisationhow much of its work is in this field, counted up to 10× the world share
10%
Sizeits output in this field, on a log scale
30%
Growthoutput growth, counted from -20% to +20%
10%
Internationalshare of its work with a co-author abroad
10%
Each slider sets a weight; the share it gets of the score is beside it.
#UniversityScoreTop 10%SpecialisationWorksGrowth
1Harvard UniversityUnited States 74.416.9%5.0×50 -0.5%
2University of WashingtonUnited States 65.714.4%7.2×26 +22.8%
3Johns Hopkins UniversityUnited States 63.723.5%4.0×19 +1.2%
4Karolinska InstitutetSweden 58.236.8%4.9×9 -43.5%
5Stanford UniversityUnited States 57.317.4%3.6×17 +9.6%
6University of PennsylvaniaUnited States 55.613.0%6.9×23 +2.5%
7Washington University in St. LouisUnited States 54.811.7%7.3×16 +20.4%
8Sichuan UniversityChina 51.026.5%1.5×10 +142.3%
9University of CincinnatiUnited States 50.115.7%6.9×13 -5.5%
10Medical University of ViennaAustria 48.612.6%12.8×13 +6.6%

Universities only. The score blends excellence (40%), size (30%), specialisation (10%), growth (10%), international reach (10%), 2022-now; growth compares 2018-21 with 2022-25 and counts up to +20%, since a jump from a small base is mostly noise.

Every institution in Polyomavirus and related diseases, country by country

Is Polyomavirus and related diseases research growing?

Output in 2022-2025 was 3% lower than in 2018-2021, peaking in 2020.

still counting19801990200020102020
grewheldshrank

The same series as a ribbon: one cell per year, darker for more. The line above answers how much; this answers when.

Its share of all research

Growing output can still be a shrinking share: all of science grows. This is Polyomavirus and related diseases as a percentage of every work published that year, 0.015% in 2024.

still counting0.020%0.040%0.060%Polyomavirus and related diseases0.015% in 202519801990200020102020

Fractional works of Polyomavirus and related diseases over all fractional works that year. How the balance of science has shifted.

How much of it reaches the world top 10%

Year by year.

still counting5%10%15%Polyomavirus and related diseases10.2% in 2025200020102020

Of each year's works in it, the share that reached the world's 10% most cited for their field and year. A field is the world for its own topics, so there is no other line to hold it against.

Which topics inside it are moving

Growth and decline on one axis around a shared zero. Two lists side by side hide the thing that matters: whether the growth dwarfs the decline, or the other way round.

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